HK1079547A1 - Cell growth inhibitors containing anti-glypican 3 antibody - Google Patents

Cell growth inhibitors containing anti-glypican 3 antibody

Info

Publication number
HK1079547A1
HK1079547A1 HK05111542A HK05111542A HK1079547A1 HK 1079547 A1 HK1079547 A1 HK 1079547A1 HK 05111542 A HK05111542 A HK 05111542A HK 05111542 A HK05111542 A HK 05111542A HK 1079547 A1 HK1079547 A1 HK 1079547A1
Authority
HK
Hong Kong
Prior art keywords
antibody
glypican
cell growth
containing anti
growth inhibitors
Prior art date
Application number
HK05111542A
Other languages
English (en)
Inventor
Tetsuo Nakamura
Masayuki Tsuchiya
Hiroyuki Aburatani
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of HK1079547A1 publication Critical patent/HK1079547A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3076—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734—Complement-dependent cytotoxicity [CDC]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
HK05111542A 2001-06-22 2005-12-15 Cell growth inhibitors containing anti-glypican 3 antibody HK1079547A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001189443 2001-06-22
PCT/JP2002/006237 WO2003000883A1 (en) 2001-06-22 2002-06-21 Cell proliferation inhibitors containing anti-glypican 3 antibody

Publications (1)

Publication Number Publication Date
HK1079547A1 true HK1079547A1 (en) 2006-04-07

Family

ID=19028362

Family Applications (2)

Application Number Title Priority Date Filing Date
HK05111542A HK1079547A1 (en) 2001-06-22 2005-12-15 Cell growth inhibitors containing anti-glypican 3 antibody
HK08112277.1A HK1120522A1 (en) 2001-06-22 2008-11-07 Cell growth inhibitors containing anti-glypican 3 antibody

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK08112277.1A HK1120522A1 (en) 2001-06-22 2008-11-07 Cell growth inhibitors containing anti-glypican 3 antibody

Country Status (15)

Country Link
US (3) US20040236080A1 (ko)
EP (3) EP1780273B1 (ko)
JP (7) JP4281869B2 (ko)
KR (3) KR20080077295A (ko)
CN (2) CN101240022B (ko)
AT (2) ATE407204T1 (ko)
AU (2) AU2002315857B2 (ko)
CA (1) CA2451493C (ko)
CY (1) CY1113854T1 (ko)
DE (2) DE60237929D1 (ko)
DK (2) DK1411118T3 (ko)
ES (3) ES2353335T3 (ko)
HK (2) HK1079547A1 (ko)
PT (2) PT1411118E (ko)
WO (1) WO2003000883A1 (ko)

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EP1411118A4 (en) 2005-01-26
AU2007201255B2 (en) 2010-03-11
EP1780273A1 (en) 2007-05-02
DK2208784T3 (da) 2013-03-18
CN1688692A (zh) 2005-10-26
PT1411118E (pt) 2008-12-09
DK1411118T3 (da) 2008-11-17
US20070172488A1 (en) 2007-07-26
AU2007201255A1 (en) 2007-04-19
EP1780273B1 (en) 2010-10-06
JP2005225892A (ja) 2005-08-25
HK1120522A1 (en) 2009-04-03
WO2003000883A1 (en) 2003-01-03
CA2451493A1 (en) 2003-01-03
ES2353335T3 (es) 2011-03-01
JP2008120828A (ja) 2008-05-29
JP2007238632A (ja) 2007-09-20
US8263077B2 (en) 2012-09-11
JP4347402B2 (ja) 2009-10-21
CY1113854T1 (el) 2016-07-27
CA2451493C (en) 2016-08-23
ES2312586T3 (es) 2009-03-01
ATE407204T1 (de) 2008-09-15
JP4281869B2 (ja) 2009-06-17
EP1411118A1 (en) 2004-04-21
US20040236080A1 (en) 2004-11-25
CN101240022A (zh) 2008-08-13
KR20080077295A (ko) 2008-08-21
US7744880B2 (en) 2010-06-29
CN101240022B (zh) 2012-07-18
US20110002922A1 (en) 2011-01-06
KR100877176B1 (ko) 2009-01-07
JP2007051159A (ja) 2007-03-01
KR20090107091A (ko) 2009-10-12
KR20040030699A (ko) 2004-04-09
EP2208784B1 (en) 2013-01-02
CN1314803C (zh) 2007-05-09
EP2208784A1 (en) 2010-07-21
JP5596935B2 (ja) 2014-09-24
KR100953520B1 (ko) 2010-04-21
DE60237929D1 (de) 2010-11-18
EP1411118B1 (en) 2008-09-03
AU2002315857B2 (en) 2007-07-26
JPWO2003000883A1 (ja) 2004-10-07
ATE483801T1 (de) 2010-10-15
DE60228721D1 (en) 2008-10-16
PT2208784E (pt) 2013-04-03
JP2009024020A (ja) 2009-02-05
JP2009161565A (ja) 2009-07-23
ES2399028T3 (es) 2013-03-25

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