HK1051708A1 - Process for the preparation of dihydroxy esters and derivatives thereof - Google Patents

Process for the preparation of dihydroxy esters and derivatives thereof

Info

Publication number
HK1051708A1
HK1051708A1 HK03103991A HK03103991A HK1051708A1 HK 1051708 A1 HK1051708 A1 HK 1051708A1 HK 03103991 A HK03103991 A HK 03103991A HK 03103991 A HK03103991 A HK 03103991A HK 1051708 A1 HK1051708 A1 HK 1051708A1
Authority
HK
Hong Kong
Prior art keywords
derivatives
preparation
dihydroxy esters
dihydroxy
esters
Prior art date
Application number
HK03103991A
Other languages
English (en)
Inventor
Robert Antony Holt
Andrew John Blacker
Christopher David Reeve
Original Assignee
Astrazeneca Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Uk Ltd filed Critical Astrazeneca Uk Ltd
Publication of HK1051708A1 publication Critical patent/HK1051708A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/03—Preparation of carboxylic acid esters by reacting an ester group with a hydroxy group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/675—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids of saturated hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
HK03103991A 2000-05-09 2003-06-05 Process for the preparation of dihydroxy esters and derivatives thereof HK1051708A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0011120.3A GB0011120D0 (en) 2000-05-09 2000-05-09 Process
PCT/GB2001/001915 WO2001085975A1 (en) 2000-05-09 2001-05-01 Process for the preparation of dihydroxy esters and derivatives thereof

Publications (1)

Publication Number Publication Date
HK1051708A1 true HK1051708A1 (en) 2003-08-15

Family

ID=9891211

Family Applications (3)

Application Number Title Priority Date Filing Date
HK03103991A HK1051708A1 (en) 2000-05-09 2003-06-05 Process for the preparation of dihydroxy esters and derivatives thereof
HK06110633A HK1090090A1 (en) 2000-05-09 2006-09-22 Process for the preparation of dihydroxy esters and derivatives thereof
HK07101586.1A HK1096998A1 (en) 2000-05-09 2007-02-09 Process for the preparation of dihydroxy esters and derivatives thereof

Family Applications After (2)

Application Number Title Priority Date Filing Date
HK06110633A HK1090090A1 (en) 2000-05-09 2006-09-22 Process for the preparation of dihydroxy esters and derivatives thereof
HK07101586.1A HK1096998A1 (en) 2000-05-09 2007-02-09 Process for the preparation of dihydroxy esters and derivatives thereof

Country Status (34)

Country Link
US (4) US7157255B2 (uk)
EP (3) EP1282719B1 (uk)
JP (1) JP4733901B2 (uk)
KR (2) KR100914675B1 (uk)
CN (1) CN1196793C (uk)
AR (2) AR028074A1 (uk)
AT (3) ATE369437T1 (uk)
AU (2) AU2001252383B2 (uk)
BR (1) BR0110667A (uk)
CA (2) CA2408004C (uk)
CY (3) CY1105376T1 (uk)
CZ (3) CZ302632B6 (uk)
DE (3) DE60141424D1 (uk)
DK (3) DK1282719T3 (uk)
EE (1) EE05062B1 (uk)
ES (3) ES2264981T3 (uk)
GB (1) GB0011120D0 (uk)
HK (3) HK1051708A1 (uk)
HU (1) HUP0302216A3 (uk)
IL (4) IL152608A0 (uk)
IS (1) IS2290B (uk)
MX (1) MXPA02010955A (uk)
MY (1) MY127751A (uk)
NO (1) NO20025377L (uk)
NZ (1) NZ522407A (uk)
PL (3) PL208379B1 (uk)
PT (3) PT1282719E (uk)
RU (1) RU2266961C2 (uk)
SI (3) SI1657310T1 (uk)
SK (2) SK287524B6 (uk)
TW (1) TWI240753B (uk)
UA (1) UA73774C2 (uk)
WO (1) WO2001085975A1 (uk)
ZA (1) ZA200208937B (uk)

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CN102373250B (zh) * 2011-11-08 2012-08-22 张家港市信谊化工有限公司 阿伐他汀钙侧链中间体的制备方法
CN102618596A (zh) * 2012-03-20 2012-08-01 中国药科大学 一种非水相体系中生物转化制备关附庚素的方法
WO2014203045A1 (en) 2013-06-20 2014-12-24 Lupin Limited A novel, green and cost effective process for synthesis of tert-butyl (3r,5s)-6-oxo-3,5-dihydroxy-3,5-o-isopropylidene-hexanoate
CN105503816B (zh) * 2016-02-17 2018-02-13 中节能万润股份有限公司 一种固体(4R‑cis)‑6‑甲酰基‑2,2‑二甲基‑1,3‑二氧己环‑4‑乙酸叔丁酯的制备方法
CN108530416B (zh) * 2017-11-02 2020-05-12 江苏阿尔法药业有限公司 一种瑞舒伐他汀中间体的制备方法
CN109574830B (zh) * 2019-01-04 2021-04-13 浙江宏元药业股份有限公司 一种瑞舒伐他汀钙中间体及其制备方法和应用
KR102384854B1 (ko) 2021-06-15 2022-04-11 한대성 풀빅산 및 일라이트를 이용한 침대

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Also Published As

Publication number Publication date
JP4733901B2 (ja) 2011-07-27
ATE458823T1 (de) 2010-03-15
US20060194297A1 (en) 2006-08-31
US20100209984A1 (en) 2010-08-19
IL193405A0 (en) 2009-02-11
DE60141424D1 (de) 2010-04-08
GB0011120D0 (en) 2000-06-28
DE60120685T2 (de) 2007-06-14
UA73774C2 (en) 2005-09-15
CA2408004C (en) 2010-04-13
MY127751A (en) 2006-12-29
SK287524B6 (sk) 2011-01-04
ATE330020T1 (de) 2006-07-15
BR0110667A (pt) 2003-03-25
ES2289722T3 (es) 2008-02-01
US20080280336A1 (en) 2008-11-13
IS2290B (is) 2007-10-15
PL208359B1 (pl) 2011-04-29
JP2003532427A (ja) 2003-11-05
HUP0302216A2 (hu) 2003-10-28
PT1726658E (pt) 2010-04-15
IL193404A (en) 2010-04-29
DK1282719T3 (da) 2006-10-02
NO20025377L (no) 2003-01-07
AR070946A2 (es) 2010-05-19
PL208379B1 (pl) 2011-04-29
ATE369437T1 (de) 2007-08-15
PL208377B1 (pl) 2011-04-29
KR100914675B1 (ko) 2009-08-28
SK286746B6 (sk) 2009-04-06
PT1657310E (pt) 2007-09-26
ZA200208937B (en) 2003-08-28
CA2677945A1 (en) 2001-11-15
SI1726658T1 (sl) 2010-05-31
TWI240753B (en) 2005-10-01
US7157255B2 (en) 2007-01-02
NZ522407A (en) 2004-06-25
CY1105376T1 (el) 2010-04-28
EP1657310A1 (en) 2006-05-17
NO20025377D0 (no) 2002-11-08
US20030134900A1 (en) 2003-07-17
SK15892002A3 (sk) 2003-04-01
IL152608A (en) 2009-05-04
CZ302632B6 (cs) 2011-08-10
CA2408004A1 (en) 2001-11-15
CZ20023675A3 (cs) 2003-02-12
KR100996977B1 (ko) 2010-11-26
EP1282719A1 (en) 2003-02-12
PL359336A1 (en) 2004-08-23
DE60129865T2 (de) 2008-05-08
CY1109991T1 (el) 2014-09-10
HUP0302216A3 (en) 2011-03-28
DK1726658T3 (da) 2010-05-17
EP1726658A3 (en) 2008-12-24
SI1282719T1 (sl) 2006-10-31
EP1726658A2 (en) 2006-11-29
EE05062B1 (et) 2008-08-15
ES2340190T3 (es) 2010-05-31
IL152608A0 (en) 2003-06-24
CY1106910T1 (el) 2012-09-26
DE60129865D1 (de) 2007-09-20
KR20080042129A (ko) 2008-05-14
HK1090090A1 (en) 2006-12-15
HK1096998A1 (en) 2007-06-15
MXPA02010955A (es) 2003-05-27
PT1282719E (pt) 2006-09-29
US7888083B2 (en) 2011-02-15
IS6609A (is) 2002-11-07
AU2001252383B2 (en) 2005-04-14
US7416865B2 (en) 2008-08-26
WO2001085975A1 (en) 2001-11-15
AR028074A1 (es) 2003-04-23
CZ302674B6 (cs) 2011-08-24
RU2266961C2 (ru) 2005-12-27
AU5238301A (en) 2001-11-20
CN1196793C (zh) 2005-04-13
DE60120685D1 (de) 2006-07-27
ES2264981T3 (es) 2007-02-01
DK1657310T3 (da) 2007-10-29
IL193405A (en) 2010-04-29
EP1282719B1 (en) 2006-06-14
IL193404A0 (en) 2009-02-11
EP1657310B1 (en) 2007-08-08
EP1726658B1 (en) 2010-02-24
CZ302675B6 (cs) 2011-08-24
SI1657310T1 (sl) 2007-12-31
US7732171B2 (en) 2010-06-08
CN1440461A (zh) 2003-09-03
EE200200628A (et) 2004-04-15
KR20030032949A (ko) 2003-04-26

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