HK1047297B - 疱疹病毒株 - Google Patents

疱疹病毒株 Download PDF

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Publication number
HK1047297B
HK1047297B HK02108740.4A HK02108740A HK1047297B HK 1047297 B HK1047297 B HK 1047297B HK 02108740 A HK02108740 A HK 02108740A HK 1047297 B HK1047297 B HK 1047297B
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HK
Hong Kong
Prior art keywords
hsv1
strain
hsv
herpes virus
virus strains
Prior art date
Application number
HK02108740.4A
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English (en)
Chinese (zh)
Other versions
HK1047297A1 (en
Inventor
Stuart Coffin Robert
Original Assignee
Biovex Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27447756&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1047297(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0001475A external-priority patent/GB0001475D0/en
Priority claimed from GB0002854A external-priority patent/GB0002854D0/en
Priority claimed from GB0100288A external-priority patent/GB0100288D0/en
Priority claimed from GB0100430A external-priority patent/GB0100430D0/en
Application filed by Biovex Limited filed Critical Biovex Limited
Publication of HK1047297A1 publication Critical patent/HK1047297A1/xx
Publication of HK1047297B publication Critical patent/HK1047297B/zh

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A61K35/763—Herpes virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C12N15/869—Herpesviral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55522—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
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    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16033—Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16632—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16641—Use of virus, viral particle or viral elements as a vector
    • C12N2710/16643—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK02108740.4A 2000-01-21 2001-01-22 疱疹病毒株 HK1047297B (zh)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
GB0001475A GB0001475D0 (en) 2000-01-21 2000-01-21 Virus strains
GB0001475 2000-01-21
GB0002854A GB0002854D0 (en) 2000-02-08 2000-02-08 Virus strains
GB0002854 2000-02-08
GB0100288A GB0100288D0 (en) 2001-01-05 2001-01-05 Virus strains
GB0100288 2001-01-05
GB0100430A GB0100430D0 (en) 2001-01-06 2001-01-06 Virus strains
GB0100430 2001-01-06
PCT/GB2001/000225 WO2001053505A2 (en) 2000-01-21 2001-01-22 Herpes virus strains for gene therapy

Publications (2)

Publication Number Publication Date
HK1047297A1 HK1047297A1 (en) 2003-02-14
HK1047297B true HK1047297B (zh) 2004-10-21

Family

ID=27447756

Family Applications (2)

Application Number Title Priority Date Filing Date
HK02108740.4A HK1047297B (zh) 2000-01-21 2001-01-22 疱疹病毒株
HK02108579.0A HK1047451B (zh) 2000-01-21 2001-01-22 一種改善的，腫瘤消解、非實驗室的hsv菌株及其在治療癌症方面的用途

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK02108579.0A HK1047451B (zh) 2000-01-21 2001-01-22 一種改善的，腫瘤消解、非實驗室的hsv菌株及其在治療癌症方面的用途

Country Status (22)

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US (12) US7223593B2 (enExample)
EP (4) EP1252323B1 (enExample)
JP (6) JP4921669B2 (enExample)
KR (2) KR100802403B1 (enExample)
CN (2) CN1250732C (enExample)
AT (2) ATE282708T1 (enExample)
AU (2) AU2695101A (enExample)
BE (1) BE2016C033I2 (enExample)
BR (3) BRPI0107736B8 (enExample)
CA (2) CA2398335C (enExample)
CY (2) CY2016021I2 (enExample)
DE (2) DE60115600T2 (enExample)
DK (2) DK1252322T4 (enExample)
ES (2) ES2233600T5 (enExample)
FR (1) FR16C0026I2 (enExample)
GB (2) GB2374873C (enExample)
HK (2) HK1047297B (enExample)
IL (4) IL150678A0 (enExample)
LU (2) LU93100I2 (enExample)
NL (2) NL300821I2 (enExample)
PT (1) PT1252322E (enExample)
WO (2) WO2001053506A2 (enExample)

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BRPI0107736B8 (pt) 2021-05-25
EP1252322A2 (en) 2002-10-30
NL300821I2 (enExample) 2016-10-27
ES2233600T5 (es) 2009-06-22
US20120321599A1 (en) 2012-12-20
GB2374873A (en) 2002-10-30
EP1252322B2 (en) 2009-03-04
CY2016021I1 (el) 2016-12-14
CA2398335A1 (en) 2001-07-26
US20150232812A1 (en) 2015-08-20
JP6424145B2 (ja) 2018-11-14
GB0219033D0 (en) 2002-09-25
CA2398335C (en) 2010-12-07
US20070003571A1 (en) 2007-01-04
BR0107736A (pt) 2002-11-19
CY2016020I2 (el) 2016-12-14
GB2375113A (en) 2002-11-06
JP2003520789A (ja) 2003-07-08
US7063835B2 (en) 2006-06-20
HK1047451B (zh) 2005-03-18
WO2001053506A3 (en) 2002-05-23
US7223593B2 (en) 2007-05-29
HK1047297A1 (en) 2003-02-14
IL150678A0 (en) 2003-02-12
US20200032218A1 (en) 2020-01-30
CY2016020I1 (el) 2016-12-14
IL150677A0 (en) 2003-02-12
AU2694701A (en) 2001-07-31
US20030113348A1 (en) 2003-06-19
LU93101I2 (fr) 2016-08-08
US20200032219A1 (en) 2020-01-30
DE60115600T2 (de) 2006-07-20
US10301600B2 (en) 2019-05-28
DK1252322T4 (da) 2009-06-08
JP6644378B2 (ja) 2020-02-12
ATE312189T1 (de) 2005-12-15
CY2016021I2 (el) 2016-12-14
GB2375113B (en) 2004-10-20
AU2001226951B8 (en) 2006-10-26
KR20030032913A (ko) 2003-04-26
PT1252322E (pt) 2005-03-31
EP1252323B1 (en) 2005-12-07
DE60107203D1 (de) 2004-12-23
JP2003520044A (ja) 2003-07-02
BR0107737A (pt) 2002-11-19
US20070264282A1 (en) 2007-11-15
BE2016C033I2 (enExample) 2020-05-20
EP2177619A1 (en) 2010-04-21
JP2019048864A (ja) 2019-03-28
DK1252322T3 (da) 2005-03-14
DE60107203T2 (de) 2005-12-01
JP4921669B2 (ja) 2012-04-25
DE60107203T3 (de) 2009-07-23
GB2374873C (en) 2011-07-27

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