IL150678A0 - Herpes virus strains - Google Patents
Herpes virus strainsInfo
- Publication number
- IL150678A0 IL150678A0 IL15067801A IL15067801A IL150678A0 IL 150678 A0 IL150678 A0 IL 150678A0 IL 15067801 A IL15067801 A IL 15067801A IL 15067801 A IL15067801 A IL 15067801A IL 150678 A0 IL150678 A0 IL 150678A0
- Authority
- IL
- Israel
- Prior art keywords
- hsv1
- strain
- hsv
- herpes virus
- virus strains
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
- A61K35/763—Herpes virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C12N15/869—Herpesviral vectors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16033—Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16632—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16641—Use of virus, viral particle or viral elements as a vector
- C12N2710/16643—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0001475A GB0001475D0 (en) | 2000-01-21 | 2000-01-21 | Virus strains |
GB0002854A GB0002854D0 (en) | 2000-02-08 | 2000-02-08 | Virus strains |
GB0100288A GB0100288D0 (en) | 2001-01-05 | 2001-01-05 | Virus strains |
GB0100430A GB0100430D0 (en) | 2001-01-06 | 2001-01-06 | Virus strains |
PCT/GB2001/000225 WO2001053505A2 (en) | 2000-01-21 | 2001-01-22 | Herpes virus strains for gene therapy |
Publications (1)
Publication Number | Publication Date |
---|---|
IL150678A0 true IL150678A0 (en) | 2003-02-12 |
Family
ID=27447756
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15067701A IL150677A0 (en) | 2000-01-21 | 2001-01-22 | Virus strains |
IL15067801A IL150678A0 (en) | 2000-01-21 | 2001-01-22 | Herpes virus strains |
IL150677A IL150677A (en) | 2000-01-21 | 2002-07-10 | Virus strains |
IL150678A IL150678A (en) | 2000-01-21 | 2002-07-10 | Herpes virus strains |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15067701A IL150677A0 (en) | 2000-01-21 | 2001-01-22 | Virus strains |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL150677A IL150677A (en) | 2000-01-21 | 2002-07-10 | Virus strains |
IL150678A IL150678A (en) | 2000-01-21 | 2002-07-10 | Herpes virus strains |
Country Status (22)
Country | Link |
---|---|
US (12) | US7063835B2 (xx) |
EP (4) | EP1568779A1 (xx) |
JP (6) | JP4810042B2 (xx) |
KR (2) | KR100768408B1 (xx) |
CN (2) | CN1418255A (xx) |
AT (2) | ATE312189T1 (xx) |
AU (2) | AU2695101A (xx) |
BE (1) | BE2016C033I2 (xx) |
BR (3) | BRPI0107736B8 (xx) |
CA (2) | CA2398335C (xx) |
CY (2) | CY2016021I1 (xx) |
DE (2) | DE60115600T2 (xx) |
DK (2) | DK1252323T3 (xx) |
ES (2) | ES2233600T5 (xx) |
FR (1) | FR16C0026I2 (xx) |
GB (2) | GB2375113B (xx) |
HK (2) | HK1047451B (xx) |
IL (4) | IL150677A0 (xx) |
LU (2) | LU93101I2 (xx) |
NL (2) | NL300820I2 (xx) |
PT (1) | PT1252322E (xx) |
WO (2) | WO2001053505A2 (xx) |
Families Citing this family (175)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AUPQ425699A0 (en) | 1999-11-25 | 1999-12-23 | University Of Newcastle Research Associates Limited, The | A method of treating a malignancy in a subject and a pharmaceutical composition for use in same |
AU2695101A (en) * | 2000-01-21 | 2001-07-31 | Biovex Ltd | Virus strains |
US20050267061A1 (en) * | 2004-04-08 | 2005-12-01 | Sangamo Biosciences, Inc. | Methods and compositions for treating neuropathic and neurodegenerative conditions |
ATE508635T1 (de) | 2001-03-27 | 2011-05-15 | Catherex Inc | Virusvektoren und ihre verwendung bei therapeutischen methoden |
GB0203285D0 (en) * | 2002-02-12 | 2002-03-27 | Brown Susanne M | An herpes simplex virus complex |
JP2004099584A (ja) | 2002-05-02 | 2004-04-02 | Keio Gijuku | Hsvを用いた抗腫瘍剤 |
AU2002953436A0 (en) | 2002-12-18 | 2003-01-09 | The University Of Newcastle Research Associates Limited | A method of treating a malignancy in a subject via direct picornaviral-mediated oncolysis |
GB0317511D0 (en) * | 2003-07-25 | 2003-08-27 | Biovex Ltd | Viral vectors |
US7897146B2 (en) | 2003-11-17 | 2011-03-01 | Crusade Laboratories Limited | Treatment using herpes simplex virus |
US20070003520A1 (en) * | 2003-11-17 | 2007-01-04 | Brown Susanne M | Mutant viruses |
GB0326798D0 (en) * | 2003-11-17 | 2003-12-24 | Crusade Lab Ltd | Methods for generating mutant virus |
CA2563103C (en) * | 2004-03-31 | 2015-02-17 | Tomoki Todo | Enhancer of anticancer activity in viral therapy and method of preventing or treating cancer |
US9273326B2 (en) | 2004-04-30 | 2016-03-01 | The Brigham And Women's Hospital, Inc. | Tetracycline-regulated gene expression in HSV-1 vectors |
US10000757B2 (en) * | 2005-05-27 | 2018-06-19 | Ospedale San Raffaele S.R.L. | Gene vector |
US20080008686A1 (en) * | 2006-07-10 | 2008-01-10 | The Brigham And Women's Hospital, Inc. | Tetracycline repressor regulated oncolytic viruses |
US8450106B2 (en) * | 2007-10-17 | 2013-05-28 | The Ohio State University Research Foundation | Oncolytic virus |
US8313896B2 (en) * | 2008-04-04 | 2012-11-20 | The General Hospital Corporation | Oncolytic herpes simplex virus immunotherapy in the treatment of brain cancer |
CA2689707A1 (en) | 2009-11-16 | 2011-05-16 | Jean-Simon Diallo | Identification of the novel small molecule viral sensitizer vse1 using high-throughput screening |
CN102666843B (zh) | 2009-12-21 | 2014-10-22 | 布里格海姆妇女医院公司 | 单纯疱疹病毒疫苗 |
CN102146418B (zh) * | 2010-02-09 | 2014-01-15 | 武汉滨会生物科技有限公司 | 重组ⅱ型单纯疱疹病毒载体及其制备方法、重组病毒、药物组合物及应用 |
JPWO2011101912A1 (ja) * | 2010-02-19 | 2013-06-17 | 国立大学法人 東京大学 | 組み換えヘルペスウイルス及び組換えヘルペスウイルスを含む医薬組成物 |
EP2550298B1 (en) | 2010-03-23 | 2015-07-15 | The Regents of The University of California | Compositions and methods for self-adjuvanting vaccines against microbes and tumors |
US20130202639A1 (en) * | 2010-03-25 | 2013-08-08 | Konstantin G. Kousoulas | Synthetic Herpes Simplex Viruses for Treatment of Cancers |
US9428565B2 (en) | 2011-01-31 | 2016-08-30 | The General Hospital Corporation | Treatment and bioluminescent visualization using multimodal TRAIL molecules |
SI2753355T1 (sl) | 2011-09-08 | 2019-02-28 | New York University | Onkolitični virus herpesa simpleksa in njegove terapevtske uporabe |
WO2013052915A2 (en) | 2011-10-05 | 2013-04-11 | Genelux Corporation | Method for detecting replication or colonization of a biological therapeutic |
WO2013138522A2 (en) | 2012-03-16 | 2013-09-19 | Genelux Corporation | Methods for assessing effectiveness and monitoring oncolytic virus treatment |
US20130280170A1 (en) | 2012-04-20 | 2013-10-24 | Aladar A. Szalay | Imaging methods for oncolytic virus therapy |
WO2014018113A1 (en) | 2012-07-24 | 2014-01-30 | The General Hospital Corporation | Oncolytic virus therapy for resistant tumors |
EP2890720B1 (en) | 2012-08-30 | 2019-07-17 | The General Hospital Corporation | Compositions and methods for treating cancer |
EA201590451A1 (ru) * | 2012-08-30 | 2016-05-31 | Эмджен Инк. | Способ лечения меланомы с применением вируса простого герпеса и ингибитора иммунной контрольной точки |
US20140140959A1 (en) | 2012-10-05 | 2014-05-22 | Aladar A. Szalay | Energy Absorbing-Based Diagnostic and Therapeutic Methods Employing Nucleic Acid Molecules Encoding Chromophore-Producing Enzymes |
CN105637092B (zh) * | 2013-07-17 | 2021-06-11 | 匹兹堡大学-属高等教育联邦体系 | 用于有效基因递送应用的无毒hsv载体和用于其生产的补充细胞 |
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KR20180118249A (ko) | 2015-04-30 | 2018-10-30 | 싸이오서스 테라퓨틱스 엘티디. | B7 단백질을 암호화하는 종양세포붕괴 아데노바이러스 |
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WO2018022945A1 (en) | 2016-07-28 | 2018-02-01 | Alpine Immune Sciences, Inc. | Cd112 variant immunomodulatory proteins and uses thereof |
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- 2002-07-10 IL IL150678A patent/IL150678A/en not_active IP Right Cessation
- 2002-11-28 HK HK02108579.0A patent/HK1047451B/zh unknown
- 2002-11-30 HK HK02108740.4A patent/HK1047297B/zh unknown
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2006
- 2006-03-10 US US11/372,613 patent/US7537924B2/en not_active Expired - Lifetime
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2007
- 2007-04-23 US US11/738,807 patent/US8277818B2/en not_active Expired - Lifetime
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2009
- 2009-04-17 US US12/425,952 patent/US20090220460A1/en not_active Abandoned
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2011
- 2011-10-31 JP JP2011238257A patent/JP2012072156A/ja active Pending
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2012
- 2012-02-17 US US13/399,868 patent/US20120164108A1/en not_active Abandoned
- 2012-08-31 US US13/600,711 patent/US8680068B2/en not_active Expired - Fee Related
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2014
- 2014-02-06 US US14/174,521 patent/US20140154215A1/en not_active Abandoned
- 2014-02-07 US US14/175,855 patent/US10301600B2/en not_active Expired - Fee Related
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2015
- 2015-04-29 US US14/700,036 patent/US20150232812A1/en not_active Abandoned
- 2015-07-10 JP JP2015138227A patent/JP6424145B2/ja not_active Expired - Lifetime
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2016
- 2016-06-08 LU LU93101C patent/LU93101I2/fr unknown
- 2016-06-08 LU LU93100C patent/LU93100I2/fr unknown
- 2016-06-14 NL NL300820C patent/NL300820I2/nl unknown
- 2016-06-14 NL NL300821C patent/NL300821I2/nl unknown
- 2016-06-14 BE BE2016C033C patent/BE2016C033I2/fr unknown
- 2016-06-15 CY CY2016021C patent/CY2016021I1/el unknown
- 2016-06-15 FR FR16C0026C patent/FR16C0026I2/fr active Active
- 2016-06-15 CY CY2016020C patent/CY2016020I1/el unknown
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2017
- 2017-03-01 JP JP2017037827A patent/JP2017132779A/ja active Pending
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2018
- 2018-11-22 JP JP2018218735A patent/JP6644378B2/ja not_active Expired - Lifetime
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2019
- 2019-04-02 US US16/372,800 patent/US20200032218A1/en not_active Abandoned
- 2019-04-05 US US16/376,089 patent/US20200032219A1/en not_active Abandoned
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