GT201100023A - Anticuerpos neutralizantes del virus anti - influenza a y usos de los mismos - Google Patents
Anticuerpos neutralizantes del virus anti - influenza a y usos de los mismosInfo
- Publication number
- GT201100023A GT201100023A GT201100023A GT201100023A GT201100023A GT 201100023 A GT201100023 A GT 201100023A GT 201100023 A GT201100023 A GT 201100023A GT 201100023 A GT201100023 A GT 201100023A GT 201100023 A GT201100023 A GT 201100023A
- Authority
- GT
- Guatemala
- Prior art keywords
- antibodies
- influenza
- same
- neutralizing antibodies
- subtipe
- Prior art date
Links
- 241000700605 Viruses Species 0.000 title 1
- 206010022000 influenza Diseases 0.000 title 1
- 230000003472 neutralizing effect Effects 0.000 title 1
- 102000008394 Immunoglobulin Fragments Human genes 0.000 abstract 2
- 108010021625 Immunoglobulin Fragments Proteins 0.000 abstract 2
- 241001500351 Influenzavirus A Species 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 210000004180 plasmocyte Anatomy 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 238000010187 selection method Methods 0.000 abstract 1
- 241000712461 unidentified influenza virus Species 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1018—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8383808P | 2008-07-25 | 2008-07-25 | |
| US18158209P | 2009-05-27 | 2009-05-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GT201100023A true GT201100023A (es) | 2013-12-10 |
Family
ID=41570664
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GT201100023A GT201100023A (es) | 2008-07-25 | 2011-01-21 | Anticuerpos neutralizantes del virus anti - influenza a y usos de los mismos |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US8685402B2 (OSRAM) |
| EP (2) | EP2313433A2 (OSRAM) |
| JP (3) | JP5607620B2 (OSRAM) |
| KR (2) | KR20110049802A (OSRAM) |
| CN (2) | CN102216327A (OSRAM) |
| AU (2) | AU2009275226B2 (OSRAM) |
| BR (1) | BRPI0911699B8 (OSRAM) |
| CA (2) | CA2731686C (OSRAM) |
| CO (1) | CO6341572A2 (OSRAM) |
| CR (2) | CR20110079A (OSRAM) |
| EC (1) | ECSP11010823A (OSRAM) |
| ES (1) | ES2662519T3 (OSRAM) |
| GT (1) | GT201100023A (OSRAM) |
| IL (2) | IL210772A0 (OSRAM) |
| MA (1) | MA32577B1 (OSRAM) |
| MX (2) | MX2011000767A (OSRAM) |
| NZ (2) | NZ590891A (OSRAM) |
| RU (1) | RU2553325C2 (OSRAM) |
| WO (2) | WO2010010467A2 (OSRAM) |
| ZA (2) | ZA201101113B (OSRAM) |
Families Citing this family (78)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3524619A1 (en) | 2007-12-06 | 2019-08-14 | Dana-Farber Cancer Institute, Inc. | Antibodies against influenza virus and methods of use thereof |
| RU2553325C2 (ru) * | 2008-07-25 | 2015-06-10 | Институт Фо Ресёч Ин Биомедицин | Нейтрализующие антитела против вируса гриппа а и их использование |
| US8871207B2 (en) | 2008-07-25 | 2014-10-28 | Humabs, LLC | Neutralizing anti-influenza A virus antibodies and uses thereof |
| EP2545074A4 (en) * | 2010-03-08 | 2014-01-08 | Celltrion Inc | HUMAN MONOCLONAL ANTIBODIES MADE FROM HUMAN B-CELLS WITH NEUTRALIZING EFFECT AGAINST INFLUENZA A-VIRUS |
| CN106397584A (zh) * | 2010-06-17 | 2017-02-15 | 特瑞利斯生物科学有限责任公司 | 可用于被动流感免疫的抗体 |
| US9534042B2 (en) * | 2010-09-03 | 2017-01-03 | Fujita Health University | Influenza virus-neutralizing antibody and screening method therefor |
| WO2012045001A2 (en) * | 2010-09-30 | 2012-04-05 | Vanderbilt University | Influenza virus antibodies and immunogens and uses therefor |
| WO2012145572A1 (en) | 2011-04-20 | 2012-10-26 | The Trustees Of The University Of Pennsylvania | Regimens and compositions for aav-mediated passive immunization of airborne pathogens |
| US8961978B2 (en) | 2011-07-14 | 2015-02-24 | Crucell Holland B.V. | Human binding molecules capable of neutralizing influenza A viruses of phylogenetic group 1 and phylogenetic group 2 and influenza B viruses |
| CN107417789A (zh) * | 2011-07-18 | 2017-12-01 | 生物医学学会 | 中和抗甲型流感病毒抗体及其用途 |
| MX352338B (es) * | 2011-07-18 | 2017-11-17 | Inst Res Biomedicine | Anticuerpos neutralizantes del virus de la influenza a y usos de estos. |
| EP2739312B1 (en) * | 2011-08-03 | 2017-10-04 | Children's Medical Center Corporation | A broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza hemagglutinin |
| EP2748184A1 (en) | 2011-08-27 | 2014-07-02 | Universität Zürich | Multi-strain-reactive antibodies for therapy and diagnosis of influenza |
| EA026527B1 (ru) * | 2011-09-30 | 2017-04-28 | Селлтрион Инк. | Связующая молекула, обладающая нейтрализующей активностью в отношении вируса гриппа а, полученная из в-клеток человека |
| EP2768858B1 (en) * | 2011-10-18 | 2018-08-01 | Emory University | Antibodies directed against influenza |
| KR20130059721A (ko) * | 2011-11-29 | 2013-06-07 | (주)셀트리온 | 인간 ｂ 세포에서 생산된 인플루엔자 ａ 바이러스 중화 활성을 가지는 결합 분자 |
| SG11201402780UA (en) | 2011-12-02 | 2014-10-30 | Aimm Therapeutics Bv | Influenza a virus specific antibodies |
| CA2861515A1 (en) * | 2011-12-05 | 2013-06-13 | Trellis Bioscience, Llc | Antibodies useful in passive influenza immunization |
| ES2564138T3 (es) * | 2011-12-12 | 2016-03-18 | Novartis Ag | Ensayo para Hemaglutinina del virus de la influenza |
| KR101749316B1 (ko) | 2011-12-15 | 2017-06-21 | (주) 에이프로젠 | Ｈ１ｎ１―감염된 환자들로부터 유도된 매우 잠재력 있는 넓은-스펙트럼 중화 단일클론 항체 및 이를 포함하는 바이러스의 치료용 조성물 |
| RU2502745C2 (ru) * | 2011-12-30 | 2013-12-27 | Общество с ограниченной ответственностью "Технофарма" | Наноантитело "anti-flu", рекомбинантные вирусные векторы и фармацевтические композиции для профилактики и терапии гриппа типа а |
| US8834881B2 (en) * | 2012-03-08 | 2014-09-16 | Crucell Holland B.V. | Human binding molecules capable of binding to and neutralizing influenza B viruses and uses thereof |
| US9969794B2 (en) | 2012-05-10 | 2018-05-15 | Visterra, Inc. | HA binding agents |
| US9683030B2 (en) | 2012-05-10 | 2017-06-20 | Massachusetts Institute Of Technology | Agents for influenza neutralization |
| CN103665155B (zh) * | 2012-09-14 | 2016-07-06 | 中国科学院上海生命科学研究院 | 一种抗流感病毒广谱中和性的中和分子1f2 |
| CN103665156B (zh) * | 2012-09-14 | 2016-08-03 | 中国科学院上海生命科学研究院 | 一种抗流感病毒广谱中和性的结合分子3e1 |
| CN103665157B (zh) * | 2012-09-14 | 2016-06-29 | 中国科学院上海生命科学研究院 | 一种抗流感病毒广谱中和性的中和分子1c4 |
| CN103665154B (zh) * | 2012-09-14 | 2016-08-03 | 中国科学院上海生命科学研究院 | 一种抗流感病毒广谱中和性的中和分子3c4 |
| BR112015010817A8 (pt) | 2012-11-13 | 2018-01-23 | Genentech Inc | anticorpos anti-hemaglutinina isolado, método de tratamento, inibição ou prevenção de infecções, composição, composição farmacêutica, ácido nucleico isolado, célula hospedeira, método de produção de anticorpos e uso do anticorpo anti-hemaglutinina |
| JP6595448B2 (ja) | 2013-03-14 | 2019-10-23 | コントラフェクト コーポレイション | 治療効率の増強のために鼻腔内送達する中和抗体に基づく組成物および方法 |
| KR20140118682A (ko) * | 2013-03-29 | 2014-10-08 | (주)셀트리온 | 2 이상의 인플루엔자 ａ 바이러스 중화 결합 분자를 포함하는 조성물 |
| US9650434B2 (en) | 2013-04-02 | 2017-05-16 | Xiamen University | Broad-spectrum monoclonal antibody recognizing HA1 domain of hemagglutinin of influenza virus |
| RS60938B1 (sr) * | 2013-10-02 | 2020-11-30 | Medimmune Llc | Neutrališuća antitela na grip a i njihova upotreba |
| EP3070167A4 (en) * | 2013-11-06 | 2017-06-07 | Osaka University | Antibody having broad neutralizing activity in group 1 influenza a virus |
| US10639370B2 (en) | 2014-02-04 | 2020-05-05 | Contrafect Corporation | Antibodies useful in passive influenza immunization, and compositions, combinations and methods for use thereof |
| RU2720282C1 (ru) | 2014-02-04 | 2020-04-28 | Контрафект Корпорейшн | Антитела, подходящие для пассивной иммунизации против гриппа, и их композиции, комбинации и способы применения |
| CN110642944B (zh) * | 2014-03-07 | 2021-06-11 | 神州细胞工程有限公司 | 一种中和人感染h7n9甲型流感病毒的抗体及其用途 |
| PT3142750T (pt) | 2014-05-13 | 2020-09-22 | Univ Pennsylvania | Composições que compreendem aav expressando construções de anticorpos duplos e suas utilizações |
| US10077309B2 (en) * | 2014-07-14 | 2018-09-18 | The Penn State Research Foundation | Compositions and methods for targeting of the surfactant protein A receptor |
| WO2016011035A2 (en) | 2014-07-15 | 2016-01-21 | Medlmmune, Llc | Neutralizing anti-influenza b antibodies and uses thereof |
| WO2016010160A1 (ja) * | 2014-07-18 | 2016-01-21 | 国立感染症研究所長が代表する日本国 | 抗インフルエンザウイルス抗体及びその利用 |
| WO2016089181A1 (ko) * | 2014-12-05 | 2016-06-09 | (주)셀트리온 | 1 이상의 인플루엔자 바이러스 중화 결합 분자를 포함하는 애주번트 조성물 및 이를 포함하는 백신 조성물 |
| US20180008702A1 (en) | 2014-12-05 | 2018-01-11 | Celltrion Inc. | Adjuvant composition containing at least one influenza virus neutralizing and binding molecule and vaccine composition containing same |
| TWI702229B (zh) | 2014-12-19 | 2020-08-21 | 美商再生元醫藥公司 | 流行性感冒病毒血球凝集素之人類抗體 |
| MA48852A (fr) | 2015-05-13 | 2020-04-01 | Univ Pennsylvania | Expression médiée par aav d'anticorps anti-grippaux et leurs procédés d'utilisation |
| PT3303384T (pt) | 2015-06-01 | 2021-10-14 | Medimmune Llc | Moléculas de ligação neutralizantes anti-influenza e suas utilizações |
| WO2017083627A1 (en) | 2015-11-13 | 2017-05-18 | Visterra, Inc. | Compositions and methods for treating and preventing influenza |
| IL304940A (en) | 2016-01-13 | 2023-10-01 | Medimmune Llc | A method for treating type A influenza |
| CN109195629A (zh) | 2016-02-24 | 2019-01-11 | 威特拉公司 | 流行性感冒抗体分子制剂 |
| KR102037041B1 (ko) * | 2016-08-10 | 2019-10-29 | (주)셀트리온 | 항-인플루엔자 바이러스 항체의 안정한 액체 약제학적 제제 |
| JP2017086068A (ja) * | 2016-10-31 | 2017-05-25 | インスティテュート・フォー・リサーチ・イン・バイオメディシンＩｎｓｔｉｔｕｔｅ Ｆｏｒ Ｒｅｓｅａｒｃｈ Ｉｎ Ｂｉｏｍｅｄｉｃｉｎｅ | Ａ型インフルエンザウイルス中和抗体及びその使用法 |
| RU2656142C1 (ru) * | 2016-12-30 | 2018-05-31 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) | РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК pBiPr-ABIgA1FI6-ht ДЛЯ ПОЛУЧЕНИЯ РЕКОМБИНАНТНОГО ИММУНОГЛОБУЛИНА А ИЗОТИПА IGA1 |
| RU2671477C2 (ru) * | 2016-12-30 | 2018-10-31 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) | РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК pBiPr-ABIgA2m1F16-ht ДЛЯ ПОЛУЧЕНИЯ РЕКОМБИНАНТНОГО ИММУНОГЛОБУЛИНА А ИЗОТИПА IGA2m1 |
| RU2664184C2 (ru) * | 2016-12-30 | 2018-08-15 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) | РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК pBiPr-ABIgA1FI6-Intht ДЛЯ ПОЛУЧЕНИЯ РЕКОМБИНАНТНОГО ИММУНОГЛОБУЛИНА А ИЗОТИПА IgA1 |
| JOP20190200A1 (ar) | 2017-02-28 | 2019-08-27 | Univ Pennsylvania | تركيبات نافعة في معالجة ضمور العضل النخاعي |
| WO2018160582A1 (en) | 2017-02-28 | 2018-09-07 | The Trustees Of The University Of Pennsylvania | Adeno-associated virus (aav) clade f vector and uses therefor |
| WO2018160573A1 (en) | 2017-02-28 | 2018-09-07 | The Trustees Of The University Of Pennsylvania | Influenza vaccines based on aav vectors |
| JP7403733B2 (ja) | 2017-09-04 | 2023-12-25 | 国立感染症研究所長 | インフルエンザｈａスプリットワクチンの製造方法 |
| BR112020005166A2 (pt) | 2017-09-18 | 2020-09-24 | Amyris, Inc. | métodos para integração genômica para células hospedeiras de kluyveromyces |
| US11390874B2 (en) * | 2017-09-18 | 2022-07-19 | Amyris, Inc. | Methods for genomic integration in pichia and other host cells |
| CN109988236B (zh) * | 2017-12-30 | 2022-04-01 | 中国科学院天津工业生物技术研究所 | 一种流感病毒抗体的应用 |
| BR112020014343A2 (pt) * | 2018-01-23 | 2020-12-08 | Janssen Vaccines & Prevention B.V. | Vacinas contra o vírus da influenza e seus usos |
| JP6622825B2 (ja) * | 2018-01-25 | 2019-12-18 | インスティテュート・フォー・リサーチ・イン・バイオメディシンＩｎｓｔｉｔｕｔｅ Ｆｏｒ Ｒｅｓｅａｒｃｈ Ｉｎ Ｂｉｏｍｅｄｉｃｉｎｅ | Ａ型インフルエンザウイルス中和抗体及びその使用法 |
| US11780907B2 (en) | 2018-01-26 | 2023-10-10 | Regeneron Pharmaceuticals, Inc. | Human antibodies to influenza hemagglutinin |
| IL280332B2 (en) | 2018-07-23 | 2025-05-01 | Japan As Represented By Director General Of Nat Institute Of Infectious Diseases | A preparation containing influenza vaccine |
| EP3917564A4 (en) | 2019-02-01 | 2022-12-21 | NovaRock Biotherapeutics, Ltd. | ANTI-CLAUDINE 18 ANTIBODIES AND THEIR METHODS OF USE |
| JP7545955B2 (ja) | 2019-03-04 | 2024-09-05 | 国立感染症研究所長 | インフルエンザｈａスプリットワクチンの製造方法 |
| CA3132521A1 (en) | 2019-03-25 | 2020-10-01 | Visterra, Inc. | Compositions and methods for treating and preventing influenza |
| JP2020048568A (ja) * | 2019-11-22 | 2020-04-02 | インスティテュート・フォー・リサーチ・イン・バイオメディシンＩｎｓｔｉｔｕｔｅ Ｆｏｒ Ｒｅｓｅａｒｃｈ Ｉｎ Ｂｉｏｍｅｄｉｃｉｎｅ | Ａ型インフルエンザウイルス中和抗体及びその使用法 |
| WO2021119467A1 (en) | 2019-12-11 | 2021-06-17 | Visterra, Inc. | Compositions and methods for treating and preventing influenza |
| WO2021201677A1 (en) | 2020-04-01 | 2021-10-07 | Kiadis Pharma Intellectual Property B.V. | Compositions and methods targeting influenza |
| CN111825763B (zh) * | 2020-07-15 | 2022-04-19 | 扬州大学 | 流感病毒ha蛋白茎部特异性单克隆抗体及其制备方法和应用 |
| CN114181303B (zh) * | 2020-09-14 | 2022-12-23 | 东莞市朋志生物科技有限公司 | 抗甲型流感病毒的抗体和试剂盒 |
| US20240024507A1 (en) | 2020-12-01 | 2024-01-25 | The Trustees Of The University Of Pennsylvania | Novel compositions with tissue-specific targeting motifs and compositions containing same |
| MX2023012643A (es) | 2021-04-27 | 2024-01-05 | Generation Bio Co | Vectores de adn no virales que expresan anticuerpos terapéuticos y usos de estos. |
| KR20240161965A (ko) | 2022-03-14 | 2024-11-13 | 제너레이션 바이오 컴퍼니 | 이종 프라임 부스트 백신 조성물 및 사용 방법 |
| KR20240088574A (ko) | 2022-11-21 | 2024-06-20 | (주)샤페론 | 인플루엔자 바이러스에 대한 단일 도메인 항체 및 이의 용도 |
| CN119930806B (zh) * | 2025-01-21 | 2025-12-02 | 中国医学科学院病原生物学研究所 | 一种甲型流感病毒中和抗体及其应用 |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US630064A (en) * | 1899-02-10 | 1899-08-01 | William Martindale | Safety-hook. |
| NL154600B (nl) * | 1971-02-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen. |
| US3817837A (en) * | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
| US3766162A (en) | 1971-08-24 | 1973-10-16 | Hoffmann La Roche | Barbituric acid antigens and antibodies specific therefor |
| US4179337A (en) * | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| US4233402A (en) | 1978-04-05 | 1980-11-11 | Syva Company | Reagents and method employing channeling |
| JPS5896026A (ja) | 1981-10-30 | 1983-06-07 | Nippon Chemiphar Co Ltd | 新規ウロキナ−ゼ誘導体およびその製造法ならびにそれを含有する血栓溶解剤 |
| EP0098110B1 (en) | 1982-06-24 | 1989-10-18 | NIHON CHEMICAL RESEARCH KABUSHIKI KAISHA also known as JAPAN CHEMICAL RESEARCH CO., LTD | Long-acting composition |
| US5807715A (en) * | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| US4766106A (en) * | 1985-06-26 | 1988-08-23 | Cetus Corporation | Solubilization of proteins for pharmaceutical compositions using polymer conjugation |
| US4676980A (en) | 1985-09-23 | 1987-06-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target specific cross-linked heteroantibodies |
| US4831175A (en) | 1986-09-05 | 1989-05-16 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Backbone polysubstituted chelates for forming a metal chelate-protein conjugate |
| RU2031941C1 (ru) * | 1991-03-14 | 1995-03-27 | Научно-исследовательский институт гриппа РАМН | Штамм вируса гриппа а(нini) для получения живой гриппозной интраназальной вакцины для взрослых и детей |
| US5595721A (en) | 1993-09-16 | 1997-01-21 | Coulter Pharmaceutical, Inc. | Radioimmunotherapy of lymphoma using anti-CD20 |
| ES2176484T3 (es) * | 1995-08-18 | 2002-12-01 | Morphosys Ag | Bancos de proteinas/(poli)peptidos. |
| US6300104B1 (en) * | 1997-06-19 | 2001-10-09 | The Regents Of The University Of California | Secretory immunoglobulin produced by single cells and methods for making and using same |
| MY133346A (en) | 1999-03-01 | 2007-11-30 | Biogen Inc | Kit for radiolabeling ligands with yttrium-90 |
| US20020102208A1 (en) | 1999-03-01 | 2002-08-01 | Paul Chinn | Radiolabeling kit and binding assay |
| JP4656478B2 (ja) * | 2000-02-22 | 2011-03-23 | 株式会社医学生物学研究所 | 抗体ライブラリー |
| AU2003251809A1 (en) | 2002-07-11 | 2004-02-02 | The General Hospital Corporation | Polynucleotide and polypeptide fat metabolism regulators and uses thereof |
| CN1756562A (zh) * | 2003-03-07 | 2006-04-05 | 麦克公司 | 流感病毒疫苗 |
| CN103446582A (zh) | 2003-08-11 | 2013-12-18 | 财团法人阪大微生物病研究会 | 包含诱导粘膜免疫的佐剂的新型疫苗 |
| WO2006124269A2 (en) | 2005-05-16 | 2006-11-23 | Amgen Fremont Inc. | Human monoclonal antibodies that bind to very late antigen-1 for the treatment of inflammation and other disorders |
| EP1957530A2 (en) | 2005-10-21 | 2008-08-20 | Novartis AG | Human antibodies against il13 and therapeutic uses |
| TWI477602B (zh) | 2006-02-09 | 2015-03-21 | Educational Foundation Jichi Medical Univ | Novel viral vector |
| US20080014205A1 (en) * | 2006-05-15 | 2008-01-17 | Lawrence Horowitz | Neutralizing Antibodies to Influenza Viruses |
| EA017203B1 (ru) * | 2006-09-07 | 2012-10-30 | Круселл Холланд Б.В. | Связывающие молекулы человека, способные нейтрализовать вирус гриппа h5n1, и их применение |
| PL2069403T3 (pl) | 2006-10-02 | 2015-08-31 | Regeneron Pharma | Przeciwciała ludzkie o wysokim powinowactwie wobec receptora ludzkiej IL-4 |
| JP5601836B2 (ja) | 2006-11-08 | 2014-10-08 | マクロジェニックス ウエスト， インコーポレイテッド | Ｔｅｓ７およびｔｅｓ７に結合する抗体 |
| EP1925318A1 (en) * | 2006-11-20 | 2008-05-28 | Paul-Ehrlich-Institut | Recombinant modified vaccinia virus Ankara (MVA)-based vaccine for the avian flu |
| NO347649B1 (no) * | 2006-12-14 | 2024-02-12 | Regeneron Pharma | Humant antistoff eller antistoff fragment som spesifikt binder human deltaliknende ligand 4 (hDII4), nukleinsyremolekyl som koder for slike og vektor og vert-vektorsystemer, samt fremgangsmåte for fremstilling, sammensetning og anvendelse. |
| GB0700133D0 (en) | 2007-01-04 | 2007-02-14 | Humabs Llc | Human cytomegalovirus neutralising antibodies and use thereof |
| EP2125886A2 (en) | 2007-03-13 | 2009-12-02 | Humabs LLC | Antibodies against h5n1 strains of influenza a virus |
| ITTO20080204A1 (it) | 2008-03-17 | 2009-09-18 | Pomona Biotechnologies Llc | Anticorpi monoclonali atti a reagire con una pluralita di sottotipi del virus influenzale a |
| US8871207B2 (en) * | 2008-07-25 | 2014-10-28 | Humabs, LLC | Neutralizing anti-influenza A virus antibodies and uses thereof |
| RU2553325C2 (ru) | 2008-07-25 | 2015-06-10 | Институт Фо Ресёч Ин Биомедицин | Нейтрализующие антитела против вируса гриппа а и их использование |
-
2009
- 2009-07-27 RU RU2011105062/10A patent/RU2553325C2/ru active
- 2009-07-27 NZ NZ590891A patent/NZ590891A/xx not_active IP Right Cessation
- 2009-07-27 CA CA2731686A patent/CA2731686C/en active Active
- 2009-07-27 CN CN2009801329884A patent/CN102216327A/zh active Pending
- 2009-07-27 US US12/509,835 patent/US8685402B2/en active Active
- 2009-07-27 NZ NZ590890A patent/NZ590890A/xx not_active IP Right Cessation
- 2009-07-27 CN CN200980132989.9A patent/CN102164613B/zh active Active
- 2009-07-27 WO PCT/IB2009/006623 patent/WO2010010467A2/en not_active Ceased
- 2009-07-27 EP EP09759983A patent/EP2313433A2/en not_active Withdrawn
- 2009-07-27 AU AU2009275226A patent/AU2009275226B2/en active Active
- 2009-07-27 KR KR1020117003495A patent/KR20110049802A/ko not_active Withdrawn
- 2009-07-27 JP JP2011519252A patent/JP5607620B2/ja active Active
- 2009-07-27 KR KR1020117003526A patent/KR101732056B1/ko active Active
- 2009-07-27 MX MX2011000767A patent/MX2011000767A/es active IP Right Grant
- 2009-07-27 BR BRPI0911699A patent/BRPI0911699B8/pt active IP Right Grant
- 2009-07-27 JP JP2011519253A patent/JP2011528902A/ja active Pending
- 2009-07-27 ES ES09745097.7T patent/ES2662519T3/es active Active
- 2009-07-27 EP EP09745097.7A patent/EP2313112B1/en active Active
- 2009-07-27 CA CA2733218A patent/CA2733218A1/en not_active Abandoned
- 2009-07-27 WO PCT/IB2009/006616 patent/WO2010010466A2/en not_active Ceased
- 2009-07-27 MX MX2011000768A patent/MX2011000768A/es not_active Application Discontinuation
- 2009-07-27 AU AU2009275227A patent/AU2009275227A1/en not_active Abandoned
- 2009-07-27 US US12/509,731 patent/US9340603B2/en active Active
-
2011
- 2011-01-20 IL IL210772A patent/IL210772A0/en unknown
- 2011-01-20 IL IL210771A patent/IL210771A0/en unknown
- 2011-01-21 GT GT201100023A patent/GT201100023A/es unknown
- 2011-02-09 CO CO11015221A patent/CO6341572A2/es active IP Right Grant
- 2011-02-11 EC EC2011010823A patent/ECSP11010823A/es unknown
- 2011-02-11 ZA ZA2011/01113A patent/ZA201101113B/en unknown
- 2011-02-11 CR CR20110079A patent/CR20110079A/es unknown
- 2011-02-14 ZA ZA2011/01150A patent/ZA201101150B/en unknown
- 2011-02-14 CR CR20110084A patent/CR20110084A/es unknown
- 2011-02-22 MA MA33633A patent/MA32577B1/fr unknown
-
2014
- 2014-08-28 JP JP2014174221A patent/JP6022515B2/ja active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GT201100023A (es) | Anticuerpos neutralizantes del virus anti - influenza a y usos de los mismos | |
| CY1124043T1 (el) | Εξουδετερωτικα αντισωματα του ανθρωπινου ιου της ανοσοανεπαρκειας και μεθοδοι χρησης αυτων | |
| ECSP11010827A (es) | Citomegalovirus humano que neutraliza anticuerpos y su uso | |
| GT201200258A (es) | Composiciones de anticuerpos anti-factor de crecimiento nervioso (ngf) | |
| CR20130016A (es) | ANTICUERPOS PEPTIDICOS BETA AMILOIDE ANTI-N3pGlu Y USOS DE LOS MISMOS | |
| CO7151488A2 (es) | Anticuerpos de reacción cruzada anti-jagged1/jagged 2, anticuerpos anti-jagged activables y métodos de uso de los mismos | |
| MX352338B (es) | Anticuerpos neutralizantes del virus de la influenza a y usos de estos. | |
| EA201490288A1 (ru) | Связывающие молекулы человека, способные нейтрализовать вирусы гриппа a филогенетической группы 1 и филогенетической группы 2 и вирусы гриппа b | |
| CY1121673T1 (el) | Εξουδετερωση αντισωματων στις κυριες εξωτοξινες tcda και tcdb της λοιμωξης clostridium difficile | |
| AR090465A1 (es) | Formas solidas de un profarmaco de nucleotidos de tiofosforamidato | |
| EA201591191A1 (ru) | Антитела против ntb-a и связанные с ними композиции и способы | |
| MX2023004869A (es) | Anticuerpos contra sars-cov-2 y usos de los mismos. | |
| PE20141158A1 (es) | El anticuerpo neutralizador del receptor de prolactina mat3 y su uso terapeutico | |
| MX2014013678A (es) | Agentes para neutralizacion de influenza. | |
| ECSP13012481A (es) | Composiciones de anticuerpo anti-vegfr-3 | |
| HK1169126A (en) | Monoclonal antibodies against influenza virus generated by cyclical administration and uses thereof | |
| TN2011000028A1 (en) | Neutralizing anti-influenza a virus antibodies and uses therof | |
| CU20140006A7 (es) | Moléculas de enlace humanas capaces de neutralizar los virus de la influenza a del grupo filogenético 1 y grupo filogenético 2 y virus de la influenza b |