SG11201402780UA - Influenza a virus specific antibodies - Google Patents

Influenza a virus specific antibodies

Info

Publication number
SG11201402780UA
SG11201402780UA SG11201402780UA SG11201402780UA SG11201402780UA SG 11201402780U A SG11201402780U A SG 11201402780UA SG 11201402780U A SG11201402780U A SG 11201402780UA SG 11201402780U A SG11201402780U A SG 11201402780UA SG 11201402780U A SG11201402780U A SG 11201402780UA
Authority
SG
Singapore
Prior art keywords
influenza
specific antibodies
virus specific
virus
antibodies
Prior art date
Application number
SG11201402780UA
Inventor
Hergen Spits
Tim Beaumont
Mark Jeroen Kwakkenbos
Arjen Quirinus Bakker
Original Assignee
Aimm Therapeutics Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aimm Therapeutics Bv filed Critical Aimm Therapeutics Bv
Publication of SG11201402780UA publication Critical patent/SG11201402780UA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1018Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
SG11201402780UA 2011-12-02 2012-12-03 Influenza a virus specific antibodies SG11201402780UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11191783 2011-12-02
PCT/NL2012/050851 WO2013081463A2 (en) 2011-12-02 2012-12-03 Influenza a virus specific antibodies

Publications (1)

Publication Number Publication Date
SG11201402780UA true SG11201402780UA (en) 2014-10-30

Family

ID=47297373

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201402780UA SG11201402780UA (en) 2011-12-02 2012-12-03 Influenza a virus specific antibodies

Country Status (8)

Country Link
US (2) US9718874B2 (en)
EP (1) EP2785737A2 (en)
JP (1) JP6325451B2 (en)
KR (1) KR20140112495A (en)
AU (3) AU2012346669B2 (en)
CA (1) CA2892992A1 (en)
SG (1) SG11201402780UA (en)
WO (1) WO2013081463A2 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007067032A1 (en) 2005-12-09 2007-06-14 Academisch Medisch Cemtrum Bij De Universiteit Van Amsterdam Means and methods for influencing the stability of cells
AU2006323315B2 (en) 2005-12-09 2014-02-20 Academisch Medisch Centrum Bij De Universiteit Van Amsterdam Means and methods for influencing the stability of antibody producing cells
DK2454283T3 (en) 2009-07-15 2018-05-07 Aimm Therapeutics Bv METHODS AND PROCEDURES FOR MANUFACTURING HIGH EFFICIENCY ANTIBODIES
PL2646466T3 (en) 2010-12-02 2017-09-29 Aimm Therapeutics B.V. Means and methods for producing high affinity antibodies
US9969794B2 (en) 2012-05-10 2018-05-15 Visterra, Inc. HA binding agents
BR112016014072B1 (en) 2013-12-17 2023-12-26 Kling Biotherapeutics B.V. ISOLATED, SYNTHETIC OR RECOMBINANT HUMAN ANTIBODY, OR A FUNCTIONAL PART THEREOF, ISOLATED NUCLEIC ACID MOLECULE, VECTOR, COMPOSITION, USE OF AN ANTIBODY OR FUNCTIONAL PART, OR A NUCLEIC ACID MOLECULE OR A VECTOR, AND, METHODS FOR PRODUCING AN ANTIBODY OR FUNCTIONAL PART, AND TO DETERMINE WHETHER AML CELLS OR LYMPHOMA CELLS OR MULTIPLE MYELOMA CELLS OR NON-HODGKIN LYMPHOMA B CELLS ARE PRESENT IN A SAMPLE
US10611829B2 (en) 2014-01-31 2020-04-07 Aimm Therapeutics B.V. Means and methods for producing stable antibodies
KR101582490B1 (en) * 2014-04-14 2016-01-19 아이디바이오 주식회사 Novel virus vaccine to form cross-protection against multiple subtypes of influenza viruses
TWI702229B (en) 2014-12-19 2020-08-21 美商再生元醫藥公司 Human antibodies to influenza hemagglutinin
WO2016209079A1 (en) 2015-06-24 2016-12-29 Aimm Therapeutics B.V. Aml antigens and uses thereof
EP3374390A1 (en) 2015-11-13 2018-09-19 Visterra, Inc. Compositions and methods for treating and preventing influenza
CN106928350B (en) * 2015-12-30 2020-11-03 中国科学院天津工业生物技术研究所 Influenza virus antibody, preparation method and application thereof
US11781112B2 (en) 2016-03-06 2023-10-10 Kareem Thomas Robinson Method of generating antigen-specific immunological memory in a subject that rejects classical vaccines
WO2019067884A1 (en) * 2017-09-28 2019-04-04 The Children's Medical Center Corporation Molecular grafting of complex, broadly neutralizing antibody epitopes
CA3088194A1 (en) 2018-01-26 2019-08-01 Regeneron Pharmaceuticals, Inc. Human antibodies to influenza hemagglutinin
CN113924147A (en) 2019-03-25 2022-01-11 威特拉公司 Compositions and methods for treating and preventing influenza
MX2022008391A (en) 2020-01-10 2022-09-29 Kling Biotherapeutics B V Epithelial cadherin-specific antibodies.
CN111298101B (en) * 2020-02-21 2023-05-30 佛山科学技术学院 Application of antibacterial peptide PG-1 in inhibiting avian influenza virus
JP2023540373A (en) * 2020-09-08 2023-09-22 ノヴェルジェン カンパニー リミテッド Antiviral composition against influenza A virus

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001062907A1 (en) 2000-02-22 2001-08-30 Medical & Biological Laboratories Co., Ltd. Antibody library
AU2003225976A1 (en) 2002-03-26 2003-10-13 Centocor, Inc. Anti-tnf antibodies, compositions, methods and uses
AU2006323315B2 (en) 2005-12-09 2014-02-20 Academisch Medisch Centrum Bij De Universiteit Van Amsterdam Means and methods for influencing the stability of antibody producing cells
MX2009002174A (en) * 2006-09-07 2009-03-12 Crucell Holland Bv Human binding molecules capable of neutralizing influenza virus h5n1 and uses thereof.
RU2448979C2 (en) 2006-12-14 2012-04-27 Ридженерон Фармасьютикалз, Инк. Human antibodies to delta-like human ligand-4
ITTO20080204A1 (en) * 2008-03-17 2009-09-18 Pomona Biotechnologies Llc MONOCLONAL ANTIBODIES ACTIONS TO REACT WITH A PLURALITY OF SUBTIPS OF THE INFLUENTIAL VIRUS A
US8871207B2 (en) 2008-07-25 2014-10-28 Humabs, LLC Neutralizing anti-influenza A virus antibodies and uses thereof
CN102216327A (en) 2008-07-25 2011-10-12 生物医学研究所 Neutralizing anti-influenza a virus antibodies and uses thereof
WO2010087994A2 (en) 2009-01-30 2010-08-05 Whitehead Institute For Biomedical Research Methods for ligation and uses thereof
ES2934102T3 (en) * 2009-05-11 2023-02-16 Janssen Vaccines & Prevention Bv Human binding molecules that can neutralize the H3N2 influenza virus and uses thereof
EP2435475B1 (en) 2009-05-26 2018-10-17 Icahn School of Medicine at Mount Sinai Monoclonal antibodies against influenza virus generated by cyclical administration and uses thereof
CA2849668A1 (en) 2010-03-08 2011-09-15 Celltrion, Inc. Human monoclonal antibodies derived from human b cells and having neutralizing activity against influenza a viruses
EA029198B1 (en) 2010-03-26 2018-02-28 Помона Ричерка С.Р.Л. FULL-LENGTH IMMUNOGLOBULINS OF THE IgG ISOTYPE CAPABLE OF RECOGNIZING A HETEROSUBTYPE NEUTRALIZING EPITOPE ON THE HEMAGGLUTININ STEM REGION AND THEIR USE AS ANTI-INFLUENZA MEDICAMENT

Also Published As

Publication number Publication date
JP6325451B2 (en) 2018-05-16
US20150010566A1 (en) 2015-01-08
KR20140112495A (en) 2014-09-23
US20170313766A1 (en) 2017-11-02
CA2892992A1 (en) 2013-06-06
US9718874B2 (en) 2017-08-01
AU2021245146A1 (en) 2021-10-21
WO2013081463A2 (en) 2013-06-06
AU2017216562A1 (en) 2017-09-07
WO2013081463A3 (en) 2013-11-14
JP2015506668A (en) 2015-03-05
EP2785737A2 (en) 2014-10-08
AU2012346669A1 (en) 2014-07-24
AU2012346669B2 (en) 2017-08-31

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