FR21C1018I2 - Dispersion solide de la forme amorphe de (r)-1(2,2-difluorobenzo(d)(1,3)dioxol-5-yl)-n-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-méthylpropane-2-yl)-1h-indol-5-yl)-cyclopropanecarboxamide - Google Patents
Dispersion solide de la forme amorphe de (r)-1(2,2-difluorobenzo(d)(1,3)dioxol-5-yl)-n-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-méthylpropane-2-yl)-1h-indol-5-yl)-cyclopropanecarboxamideInfo
- Publication number
- FR21C1018I2 FR21C1018I2 FR21C1018C FR21C1018C FR21C1018I2 FR 21C1018 I2 FR21C1018 I2 FR 21C1018I2 FR 21C1018 C FR21C1018 C FR 21C1018C FR 21C1018 C FR21C1018 C FR 21C1018C FR 21C1018 I2 FR21C1018 I2 FR 21C1018I2
- Authority
- FR
- France
- Prior art keywords
- difluorobenzo
- cyclopropanecarboxamide
- dioxol
- dihydroxypropyl
- methylpropane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
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Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31737610P | 2010-03-25 | 2010-03-25 | |
US31995310P | 2010-04-01 | 2010-04-01 | |
US32156110P | 2010-04-07 | 2010-04-07 | |
US32163610P | 2010-04-07 | 2010-04-07 | |
PCT/US2011/030032 WO2011119984A1 (fr) | 2010-03-25 | 2011-03-25 | Formes solides de (r)-1(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-n-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-méthylpropan-2-yl)-1h-indol-5-yl)cyclopropanecarboxamide |
EP11713134.2A EP2563778B1 (fr) | 2010-03-25 | 2011-03-25 | Forme cristalline de (r)-1(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-n-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-méthylpropan-2-yl)-1h-indol-5-yl)cyclopropanecarboxamide |
Publications (2)
Publication Number | Publication Date |
---|---|
FR21C1018I1 FR21C1018I1 (fr) | 2021-07-02 |
FR21C1018I2 true FR21C1018I2 (fr) | 2023-02-17 |
Family
ID=43903962
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR21C1018C Active FR21C1018I2 (fr) | 2010-03-25 | 2021-05-14 | Dispersion solide de la forme amorphe de (r)-1(2,2-difluorobenzo(d)(1,3)dioxol-5-yl)-n-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-méthylpropane-2-yl)-1h-indol-5-yl)-cyclopropanecarboxamide |
Country Status (24)
Country | Link |
---|---|
US (1) | US20110251253A1 (fr) |
EP (5) | EP2563778B1 (fr) |
JP (5) | JP5734410B2 (fr) |
CN (3) | CN109081804B (fr) |
AU (3) | AU2011230508B2 (fr) |
BR (1) | BR112012024338B1 (fr) |
CA (2) | CA3016080C (fr) |
CY (2) | CY1123794T1 (fr) |
DK (1) | DK2826776T3 (fr) |
ES (4) | ES2951520T3 (fr) |
FR (1) | FR21C1018I2 (fr) |
HR (2) | HRP20230661T1 (fr) |
HU (3) | HUE052759T2 (fr) |
IL (4) | IL222117B (fr) |
LT (2) | LT2826776T (fr) |
MX (3) | MX370904B (fr) |
NO (1) | NO2021021I1 (fr) |
NZ (3) | NZ602665A (fr) |
PL (2) | PL2826776T3 (fr) |
PT (1) | PT2826776T (fr) |
RS (1) | RS61314B1 (fr) |
RU (2) | RU2711481C2 (fr) |
SI (1) | SI2826776T1 (fr) |
WO (1) | WO2011119984A1 (fr) |
Families Citing this family (102)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100074949A1 (en) | 2008-08-13 | 2010-03-25 | William Rowe | Pharmaceutical composition and administration thereof |
KR20060088537A (ko) | 2003-09-06 | 2006-08-04 | 버텍스 파마슈티칼스 인코포레이티드 | Atp-결합 카세트 수송체의 조절자 |
US7977322B2 (en) | 2004-08-20 | 2011-07-12 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
PL1773816T3 (pl) | 2004-06-24 | 2015-06-30 | Vertex Pharma | Modulatory transporterów posiadających kasetę wiążącą ATP |
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