LT2826776T - (r)-1(2,2-difluorbenzo(d)(1,3)dioksol-5-il)-n-(1-(2,3-dihidroksipropil)-6-fluor-2-(1-hidroksi-2-metilpropan-2-il)-1h-indol-5-il)-ciklopropankarboksamido kieta amorfinės formos dispersija - Google Patents

(r)-1(2,2-difluorbenzo(d)(1,3)dioksol-5-il)-n-(1-(2,3-dihidroksipropil)-6-fluor-2-(1-hidroksi-2-metilpropan-2-il)-1h-indol-5-il)-ciklopropankarboksamido kieta amorfinės formos dispersija

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Publication number
LT2826776T
LT2826776T LTEP14172991.3T LT14172991T LT2826776T LT 2826776 T LT2826776 T LT 2826776T LT 14172991 T LT14172991 T LT 14172991T LT 2826776 T LT2826776 T LT 2826776T
Authority
LT
Lithuania
Prior art keywords
difluorobenzo
cyclopropanecarboxamide
methylpropan
dioxol
dihydroxypropyl
Prior art date
Application number
LTEP14172991.3T
Other languages
English (en)
Inventor
Ali Keshavarz-Shokri
Beili Zhang
Tim Edward Alcacio
Elaine Chungmin Lee
Yuegang Zhang
Mariusz Krawiec
Original Assignee
Vertex Pharmaceuticals Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharmaceuticals Incorporated filed Critical Vertex Pharmaceuticals Incorporated
Publication of LT2826776T publication Critical patent/LT2826776T/lt

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    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
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LTEP14172991.3T 2010-03-25 2011-03-25 (r)-1(2,2-difluorbenzo(d)(1,3)dioksol-5-il)-n-(1-(2,3-dihidroksipropil)-6-fluor-2-(1-hidroksi-2-metilpropan-2-il)-1h-indol-5-il)-ciklopropankarboksamido kieta amorfinės formos dispersija LT2826776T (lt)

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Application Number Priority Date Filing Date Title
US31737610P 2010-03-25 2010-03-25
US31995310P 2010-04-01 2010-04-01
US32163610P 2010-04-07 2010-04-07
US32156110P 2010-04-07 2010-04-07

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LT2826776T true LT2826776T (lt) 2021-01-11

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LTEP14172991.3T LT2826776T (lt) 2010-03-25 2011-03-25 (r)-1(2,2-difluorbenzo(d)(1,3)dioksol-5-il)-n-(1-(2,3-dihidroksipropil)-6-fluor-2-(1-hidroksi-2-metilpropan-2-il)-1h-indol-5-il)-ciklopropankarboksamido kieta amorfinės formos dispersija
LTPA2021508C LTPA2021508I1 (lt) 2010-03-25 2021-05-14

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US20100074949A1 (en) 2008-08-13 2010-03-25 William Rowe Pharmaceutical composition and administration thereof
KR20060088537A (ko) 2003-09-06 2006-08-04 버텍스 파마슈티칼스 인코포레이티드 Ａｔｐ-결합 카세트 수송체의 조절자
US7977322B2 (en) 2004-08-20 2011-07-12 Vertex Pharmaceuticals Incorporated Modulators of ATP-binding cassette transporters
NZ587551A (en) 2004-06-24 2012-01-12 Vertex Pharma 5-Amino-phenol derivatives such as 5-amino-2,4-di-tert-butyl-phenol
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AU2011230508B2 (en) 2016-04-28
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NZ602665A (en) 2014-10-31
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ES2951520T3 (es) 2023-10-23
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IL288388A (en) 2022-01-01
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RU2711481C2 (ru) 2020-01-17
AU2011230508A1 (en) 2012-10-18
ES2604105T3 (es) 2017-03-03
RS61314B1 (sr) 2021-02-26
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