FR11C0023I1 - - Google Patents

Info

Publication number
FR11C0023I1
FR11C0023I1 FR11C0023C FR11C0023I1 FR 11C0023 I1 FR11C0023 I1 FR 11C0023I1 FR 11C0023 C FR11C0023 C FR 11C0023C FR 11C0023 I1 FR11C0023 I1 FR 11C0023I1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
Other languages
French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of FR11C0023I1 publication Critical patent/FR11C0023I1/fr
Application granted granted Critical
Publication of FR11C0023I2 publication Critical patent/FR11C0023I2/fr
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR11C0023C 1996-06-04 2011-07-08 Derives de benzimidazole a activite antihistaminique Active FR11C0023I2 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09601236A ES2124167B1 (es) 1996-06-04 1996-06-04 Nuevos derivados del bencimidazol con actividad antihistaminica.

Publications (2)

Publication Number Publication Date
FR11C0023I1 true FR11C0023I1 (enExample) 2011-08-19
FR11C0023I2 FR11C0023I2 (fr) 2012-03-16

Family

ID=8295035

Family Applications (1)

Application Number Title Priority Date Filing Date
FR11C0023C Active FR11C0023I2 (fr) 1996-06-04 2011-07-08 Derives de benzimidazole a activite antihistaminique

Country Status (27)

Country Link
US (1) US5877187A (enExample)
EP (1) EP0818454B1 (enExample)
JP (1) JP4218991B2 (enExample)
CN (1) CN1105716C (enExample)
AR (1) AR008386A1 (enExample)
AT (1) ATE264317T1 (enExample)
AU (1) AU725700B2 (enExample)
BR (1) BR9703276A (enExample)
CA (1) CA2206754C (enExample)
CZ (1) CZ289278B6 (enExample)
DE (2) DE69728608T2 (enExample)
DK (1) DK0818454T3 (enExample)
ES (1) ES2124167B1 (enExample)
FR (1) FR11C0023I2 (enExample)
HR (1) HRP970307B1 (enExample)
HU (1) HU227598B1 (enExample)
IN (1) IN186319B (enExample)
LU (1) LU91798I2 (enExample)
MX (1) MXPA97004127A (enExample)
NO (2) NO313195B1 (enExample)
PL (1) PL188908B1 (enExample)
PT (1) PT818454E (enExample)
RU (1) RU2182150C2 (enExample)
SI (1) SI0818454T1 (enExample)
TR (1) TR199700464A3 (enExample)
TW (1) TW438794B (enExample)
ZA (1) ZA974893B (enExample)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK20182000A3 (sk) 1998-07-01 2001-08-06 Takeda Chemical Industries, Ltd. Činidlo regulujúce funkciu receptora súvisiaceho s retinoidmi
ATE259789T1 (de) 1998-11-27 2004-03-15 Abbott Gmbh & Co Kg Substituierte benzimidazole und ihre verwendung als parp inhibitoren
ES2151442B1 (es) * 1999-01-11 2001-07-01 Espanola Prod Quimicos Nuevo derivado del bencenoetanol.
US6826561B2 (en) 2000-05-22 2004-11-30 Broadcom Corporation Method and apparatus for performing a binary search on an expanded tree
DK1505066T3 (da) * 2002-04-19 2007-03-19 Faes Farma Sa Polymorf af 4-[2-[4-[1-(2-ethoxyethyl)-1H-benzimidazol-2-IL]-1-piperidinyl]ethyl]-alfa,alfa-dimethylbenzeneddikesyre
RU2288917C2 (ru) * 2002-04-19 2006-12-10 Фаэс Фарма, С.А. Полиморф 4-[2-[4-[1-(2-этоксиэтил)-1h-бензимидазол-2-ил]-1-пиперидинил]этил]-альфа, альфа-диметилбензолуксусной кислоты, способ его получения, фармацевтический препарат на его основе и его применение
KR101052433B1 (ko) * 2002-06-13 2011-07-29 버텍스 파마슈티칼스 인코포레이티드 자이라제 및/또는 토포이소머라제 ⅳ 억제제로서의 2-우레이도-6-헤테로아릴-3ｈ-벤조이미다졸-4-카복실산 유도체 및 이를 포함하는 세균 감염 치료용 약제학적 조성물
US20070188330A1 (en) * 2006-01-24 2007-08-16 Morhard Robert C System and method for detecting, monitoring, tracking and identifying explosive materials using ID marks
US7247623B2 (en) * 2005-08-19 2007-07-24 Inspire Pharmaceuticals, Inc. Method of treating dry eye disease with non-drying antihistamines
US8367704B2 (en) * 2008-02-12 2013-02-05 Yuhan Corporation Process for preparation of 2-methyl-2′ phenylpropionic acid derivatives and novel intermediate compounds
JP2010013472A (ja) * 2009-09-09 2010-01-21 Faes Farma Sa ４−［２−［１−（２−エトキシエチル）−１Ｈ−ベンズイミダゾール−２−イル］−１−ピペリジニル］エチル］−α，α−ジメチルベンゼノ酢酸の多形体
CN102675101B (zh) * 2012-05-16 2014-01-29 王蕾 2-(4-卤乙基)苯基-2-甲基丙酸酯的制备方法及合成比拉斯汀的方法
CZ307500B6 (cs) 2012-08-15 2018-10-24 Zentiva, K.S. Způsob přípravy derivátu 2-methyl-2´-fenylpropionové kyseliny využívající nové intermediáty
US20140271504A1 (en) * 2013-03-15 2014-09-18 Hercules Incorporated Composition and method of producing personal care compositions with improved deposition properties
CN103214455B (zh) * 2013-03-30 2018-08-31 北京万全德众医药生物技术有限公司 一种比拉斯汀的制备方法
CN103214454A (zh) * 2013-03-30 2013-07-24 北京万全德众医药生物技术有限公司 一种比拉斯汀晶型及制备方法
WO2014188453A2 (en) * 2013-05-24 2014-11-27 Msn Laboratories Private Limited Novel process for the preparation of 2-[4-(2-{4-[1-(2-ethoxyethyl)-1h-benzimidazol-2-yl]-1-piperidinyl}ethyl) phenyl]-2-methylpropanoic acid
CN103351380B (zh) * 2013-06-30 2019-01-22 北京万全德众医药生物技术有限公司 一种制备比拉斯汀的方法
CN104447683A (zh) * 2013-09-12 2015-03-25 天津市汉康医药生物技术有限公司 一种稳定的比拉斯汀化合物
CN103896915A (zh) * 2014-04-01 2014-07-02 中国药科大学 苯并咪唑类衍生物、其制备方法及其在医药上的应用
EP3040334A1 (en) 2014-12-29 2016-07-06 Faes Farma, S.A. New benzimidazole derivatives as antihistamine agents
CN106349214B (zh) * 2015-07-13 2020-11-03 南京长澳医药科技有限公司 一种比拉斯汀杂质的制备方法
KR102657147B1 (ko) * 2015-07-24 2024-04-12 울퀴마, 에스. 에이. 빌라스틴의 결정형 및 그의 제조 방법
CN105272977A (zh) * 2015-09-19 2016-01-27 万全万特制药江苏有限公司 一种制备比拉斯汀中间体的方法
EP3170817A1 (en) 2015-11-20 2017-05-24 Faes Farma, S.A. Co-crystals of benzimidazole compounds
EP3170816A1 (en) 2015-11-20 2017-05-24 Faes Farma, S.A. Supersaturated compositions of benzimidazole compounds
WO2017167949A1 (en) 2016-04-01 2017-10-05 Krka, D.D., Novo Mesto Crystalline forms of bilastine
EP3452462A4 (en) * 2016-05-05 2019-10-23 MSN Laboratories Private Limited, R&D Center Solid state forms of 2-[4-(2-{4-[1-(2-ethoxyethyl)-1h-benzimidazol-2-yl]-1-piperidinyl}ethyl)phenyl]-2-methylpropanoic acid and process for preparation thereof
CN107365298A (zh) * 2017-03-14 2017-11-21 罗欣生物科技（上海）有限公司 一种2‑甲基‑2’‑苯基丙酸衍生物的制备方法
CN109456316A (zh) * 2017-09-06 2019-03-12 万全万特制药江苏有限公司 一种比拉斯汀杂质的制备方法
EP3453384B1 (en) 2017-09-07 2020-05-27 Alfred E. Tiefenbacher (GmbH & Co. KG) Pharmaceutical tablet composition comprising bilastine
US11642309B2 (en) 2017-10-16 2023-05-09 Faes Farma, S.A. Aqueous compositions comprising bilastine and mometasone
ES2835287T3 (es) 2017-12-18 2021-06-22 Tiefenbacher Alfred E Gmbh & Co Kg Composición farmacéutica de comprimido que comprende la forma polimórfica 3 de bilastina y aluminometasilicato de magnesio
ES2773756R1 (es) 2017-12-18 2021-04-12 Tiefenbacher Alfred E Gmbh & Co Kg Composición farmacéutica en comprimido que comprende la forma 3 de bilastina y una carga soluble en agua
AU2019209214B2 (en) 2018-01-18 2023-11-23 Faes Farma, S.A. Ophthalmic compositions comprising bilastine, a beta-cyclodextrin and at least one gelling agent
CN109081827A (zh) * 2018-11-06 2018-12-25 北京天弘天达医药科技股份有限公司 一种比拉斯汀的制备方法及应用
EP3725298A1 (en) 2019-04-16 2020-10-21 Faes Farma, S.A. Stable and preserved pharmaceutical compositions of bilastine
PE20231844A1 (es) 2020-07-30 2023-11-21 Faes Farma Sa Sistema de liberacion de farmacos descongestivos y bilastina
CN112110893A (zh) * 2020-10-28 2020-12-22 山东齐环医药科技有限公司 一种比拉斯汀的制备方法
US20230414597A1 (en) 2020-11-18 2023-12-28 BioPharma Synergies, S. L. Orodispersible powder composition comprising an antihistamine compound
WO2022135863A1 (en) 2020-12-23 2022-06-30 Biohorm, S.L. A non-micronized bilastine composition
WO2023156559A1 (en) 2022-02-17 2023-08-24 Faes Farma, S.A. Bilastine composition for once-daily parenteral administration
WO2024224326A1 (en) * 2023-04-27 2024-10-31 Leiutis Pharmaceuticals Llp Liquid parenteral formulations of bilastine
WO2024224308A1 (en) * 2023-04-27 2024-10-31 Leiutis Pharmaceuticals Llp Liquid parenteral formulations of bilastine free of cyclodextrins

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8904174D0 (en) * 1989-02-23 1989-04-05 British Bio Technology Compounds
EP0525129A4 (en) * 1990-04-13 1993-03-24 Smith-Kline Beecham Corporation Substituted benzimidazoles
ES2048109B1 (es) * 1992-07-20 1994-12-16 Espanola Prod Quimicos Procedimiento de preparacion de nuevos derivados piperidicos del bencimidazol.
PT815860E (pt) * 1992-08-03 2006-08-31 Sepracor Inc Carboxilato de terfenadina e tratamento de desordens alergicas.
KR100333790B1 (ko) * 1993-06-25 2002-11-04 메렐 파마슈티칼스 인크. 항히스타민성4-디페닐메틸/디페닐메톡시피페리딘유도체제조용신규중간체

Also Published As

Publication number Publication date
BR9703276A (pt) 2004-08-17
FR11C0023I2 (fr) 2012-03-16
PL188908B1 (pl) 2005-05-31
PL320358A1 (en) 1997-12-08
ATE264317T1 (de) 2004-04-15
NO972525L (no) 1997-12-05
TR199700464A2 (xx) 1997-12-21
RU2182150C2 (ru) 2002-05-10
MXPA97004127A (es) 2005-07-25
CZ289278B6 (cs) 2001-12-12
CA2206754A1 (en) 1997-12-04
EP0818454A1 (en) 1998-01-14
NO2011008I2 (no) 2012-05-14
ZA974893B (en) 1997-12-30
HU9700997D0 (en) 1997-07-28
DE122011000006I1 (de) 2011-06-16
DK0818454T3 (da) 2004-07-12
AR008386A1 (es) 2000-01-19
EP0818454B1 (en) 2004-04-14
DE69728608D1 (de) 2004-05-19
CA2206754C (en) 2007-01-23
HRP970307B1 (en) 2002-02-28
TR199700464A3 (tr) 1997-12-21
AU2467297A (en) 1997-12-11
SI0818454T1 (en) 2004-08-31
JP4218991B2 (ja) 2009-02-04
CZ172397A3 (en) 1997-12-17
HUP9700997A1 (hu) 1999-09-28
AU725700B2 (en) 2000-10-19
HRP970307A2 (en) 1998-04-30
LU91798I2 (fr) 2011-05-23
IN186319B (enExample) 2001-08-04
TW438794B (en) 2001-06-07
NO972525D0 (no) 1997-06-03
PT818454E (pt) 2004-08-31
US5877187A (en) 1999-03-02
CN1176964A (zh) 1998-03-25
HU227598B1 (en) 2011-09-28
ES2124167B1 (es) 1999-09-16
JPH1059961A (ja) 1998-03-03
DE69728608T2 (de) 2005-04-21
NO313195B1 (no) 2002-08-26
NO2011008I1 (no) 2011-06-06
CN1105716C (zh) 2003-04-16
ES2124167A1 (es) 1999-01-16

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