FI68398C - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara tetrazolylalkoxikarbostyrilderivat - Google Patents

Foerfarande foer framstaellning av nya terapeutiskt anvaendbara tetrazolylalkoxikarbostyrilderivat Download PDF

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Publication number
FI68398C
FI68398C FI792699A FI792699A FI68398C FI 68398 C FI68398 C FI 68398C FI 792699 A FI792699 A FI 792699A FI 792699 A FI792699 A FI 792699A FI 68398 C FI68398 C FI 68398C
Authority
FI
Finland
Prior art keywords
group
carbostyril
formula
colorless
reaction
Prior art date
Application number
FI792699A
Other languages
English (en)
Finnish (fi)
Other versions
FI68398B (fi
FI792699A (fi
Inventor
Takao Nishi
Kazuyuki Nakagawa
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=14470137&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI68398(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of FI792699A publication Critical patent/FI792699A/fi
Publication of FI68398B publication Critical patent/FI68398B/fi
Application granted granted Critical
Publication of FI68398C publication Critical patent/FI68398C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI792699A 1978-09-01 1979-08-30 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara tetrazolylalkoxikarbostyrilderivat FI68398C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10786978A JPS5535019A (en) 1978-09-01 1978-09-01 Carbostyryl derivative
JP10786978 1978-09-01

Publications (3)

Publication Number Publication Date
FI792699A FI792699A (fi) 1980-03-02
FI68398B FI68398B (fi) 1985-05-31
FI68398C true FI68398C (fi) 1985-09-10

Family

ID=14470137

Family Applications (1)

Application Number Title Priority Date Filing Date
FI792699A FI68398C (fi) 1978-09-01 1979-08-30 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara tetrazolylalkoxikarbostyrilderivat

Country Status (23)

Country Link
US (1) US4277479A (ru)
JP (1) JPS5535019A (ru)
AR (1) AR229342A1 (ru)
AT (1) AT364363B (ru)
AU (1) AU538410B2 (ru)
BE (1) BE878548A (ru)
CA (1) CA1139761A (ru)
CH (1) CH641799A5 (ru)
DE (1) DE2934747A1 (ru)
DK (1) DK158788C (ru)
ES (1) ES483792A1 (ru)
FI (1) FI68398C (ru)
FR (1) FR2434809A1 (ru)
GB (1) GB2033893B (ru)
IT (1) IT1119929B (ru)
MX (1) MX6749E (ru)
NL (1) NL183888C (ru)
NO (1) NO153177C (ru)
PH (1) PH18452A (ru)
PT (1) PT70136A (ru)
SE (1) SE432252B (ru)
SU (1) SU1064868A3 (ru)
ZA (1) ZA794627B (ru)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
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US4803162A (en) * 1984-05-15 1989-02-07 Fluorodiagnostic Limited Partners Composition, article and process for detecting a microorganism
ES8608874A1 (es) * 1984-05-29 1986-09-01 Pfizer Un procedimiento para la preparacion de una 2-(1h)-quinolona
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DK167187A (da) 1986-04-02 1987-10-03 Otsuka Pharma Co Ltd Carbostyrilderivater og salte deraf, fremgangsmaade til fremstilling af saadanne forbindelser og laegemiddel indeholdende disse
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JPH0681752B2 (ja) * 1986-04-02 1994-10-19 大塚製薬株式会社 カルボスチリル誘導体
JP2753622B2 (ja) 1988-05-02 1998-05-20 大塚製薬株式会社 カルボスチリル誘導体
US5064837A (en) * 1989-11-13 1991-11-12 Schering Corporation 3-substituted-1-aryl-2(h)-quinolones and their pharmaceutical compositions
JPH07100648B1 (ru) * 1990-01-08 1995-11-01
TW201305B (ru) * 1991-04-03 1993-03-01 Otsuka Pharma Co Ltd
CA2093633A1 (en) * 1991-08-23 1993-02-24 Seiji Sato Carbostyril derivative and platelets aggregation inhibitory agent
JPH0776521A (ja) * 1993-09-07 1995-03-20 Otsuka Pharmaceut Co Ltd 気道炎症抑制剤
US6187790B1 (en) 1999-03-04 2001-02-13 Neal R. Cutler Use of cilostazol for treatment of sexual dysfunction
JP4060523B2 (ja) * 1999-11-24 2008-03-12 大塚製薬株式会社 カルボスチリル誘導体の製造法
US20030045547A1 (en) * 2001-05-02 2003-03-06 Shinji Aki Process for producing carbostyril derivatives
WO2001070697A1 (en) * 2000-03-20 2001-09-27 Teva Pharmaceutical Industries Ltd. Processes for preparing 6-hydroxy-3,4-dihydroquinolinone, cilostazol and n-(4-methoxyphenyl)-3-chloropropionamide
US6515128B2 (en) 2000-03-20 2003-02-04 Teva Pharmaceutical Industries Ltd. Processes for preparing cilostazol
US6825214B2 (en) * 2000-08-14 2004-11-30 Teva Pharmaceutical Industries, Ltd. Substantially pure cilostazol and processes for making same
CN1469864A (zh) * 2000-08-14 2004-01-21 ������ҩ��ҵ���޹�˾ 制备西洛他唑的方法
US6451813B1 (en) 2001-01-26 2002-09-17 R. T. Alamo Ventures I, Llc Treatment of gastroparesis in certain patient groups
US6458804B1 (en) * 2001-01-26 2002-10-01 R.T. Alamo Venturesi, Llc Methods for the treatment of central nervous system disorders in certain patient groups
US7399864B2 (en) * 2001-05-02 2008-07-15 Otsuka Pharmaceutical Co., Ltd. Process for producing carbostyril derivatives
US20050101631A1 (en) * 2002-08-01 2005-05-12 Otsuka Pharmaceuticals Company Process for producing carbostyril derivatives
JP2003063965A (ja) * 2001-06-13 2003-03-05 Otsuka Pharmaceut Factory Inc 注射用シロスタゾール水性製剤
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US6657061B2 (en) * 2001-06-29 2003-12-02 Grayson Walker Stowell Polymorphic forms of 6-[4-1(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
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US20050255155A1 (en) * 2004-05-11 2005-11-17 Glenmark Pharmaceuticals Limited Modified release cilostazol compositions
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Also Published As

Publication number Publication date
AU5039779A (en) 1980-03-06
FI68398B (fi) 1985-05-31
NO153177C (no) 1986-01-29
DK158788B (da) 1990-07-16
AR229342A1 (es) 1983-07-29
JPS6155514B2 (ru) 1986-11-28
FI792699A (fi) 1980-03-02
SE432252B (sv) 1984-03-26
FR2434809A1 (fr) 1980-03-28
DE2934747C2 (ru) 1988-01-28
IT7968748A0 (it) 1979-08-31
US4277479A (en) 1981-07-07
ZA794627B (en) 1980-08-27
DK363179A (da) 1980-03-02
SU1064868A3 (ru) 1983-12-30
NO792829L (no) 1980-03-04
DE2934747A1 (de) 1980-03-13
NL7906523A (nl) 1980-03-04
AU538410B2 (en) 1984-08-16
ES483792A1 (es) 1980-09-01
CA1139761A (en) 1983-01-18
AT364363B (de) 1981-10-12
IT1119929B (it) 1986-03-19
ATA584579A (de) 1981-03-15
NL183888C (nl) 1989-02-16
JPS5535019A (en) 1980-03-11
FR2434809B1 (ru) 1982-09-17
DK158788C (da) 1990-12-10
PH18452A (en) 1985-07-18
PT70136A (en) 1979-09-01
SE7907236L (sv) 1980-03-02
GB2033893A (en) 1980-05-29
GB2033893B (en) 1982-12-01
MX6749E (es) 1986-06-25
NO153177B (no) 1985-10-21
CH641799A5 (de) 1984-03-15
BE878548A (fr) 1979-12-17

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MA Patent expired

Owner name: OTSUKA PHARMACEUTICAL CO., LTD.