IT1119929B - Derivati del tetrazolil alcossi carbostirile e procedimento per la loro fabbricazione - Google Patents

Derivati del tetrazolil alcossi carbostirile e procedimento per la loro fabbricazione

Info

Publication number
IT1119929B
IT1119929B IT68748/79A IT6874879A IT1119929B IT 1119929 B IT1119929 B IT 1119929B IT 68748/79 A IT68748/79 A IT 68748/79A IT 6874879 A IT6874879 A IT 6874879A IT 1119929 B IT1119929 B IT 1119929B
Authority
IT
Italy
Prior art keywords
alcoss
carbostyrile
procedure
manufacture
tetrazolyl derivatives
Prior art date
Application number
IT68748/79A
Other languages
English (en)
Other versions
IT7968748A0 (it
Inventor
Nishi Takao
Nakagawa Kazuyuki
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=14470137&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IT1119929(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of IT7968748A0 publication Critical patent/IT7968748A0/it
Application granted granted Critical
Publication of IT1119929B publication Critical patent/IT1119929B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
IT68748/79A 1978-09-01 1979-08-31 Derivati del tetrazolil alcossi carbostirile e procedimento per la loro fabbricazione IT1119929B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10786978A JPS5535019A (en) 1978-09-01 1978-09-01 Carbostyryl derivative

Publications (2)

Publication Number Publication Date
IT7968748A0 IT7968748A0 (it) 1979-08-31
IT1119929B true IT1119929B (it) 1986-03-19

Family

ID=14470137

Family Applications (1)

Application Number Title Priority Date Filing Date
IT68748/79A IT1119929B (it) 1978-09-01 1979-08-31 Derivati del tetrazolil alcossi carbostirile e procedimento per la loro fabbricazione

Country Status (23)

Country Link
US (1) US4277479A (it)
JP (1) JPS5535019A (it)
AR (1) AR229342A1 (it)
AT (1) AT364363B (it)
AU (1) AU538410B2 (it)
BE (1) BE878548A (it)
CA (1) CA1139761A (it)
CH (1) CH641799A5 (it)
DE (1) DE2934747A1 (it)
DK (1) DK158788C (it)
ES (1) ES483792A1 (it)
FI (1) FI68398C (it)
FR (1) FR2434809A1 (it)
GB (1) GB2033893B (it)
IT (1) IT1119929B (it)
MX (1) MX6749E (it)
NL (1) NL183888C (it)
NO (1) NO153177C (it)
PH (1) PH18452A (it)
PT (1) PT70136A (it)
SE (1) SE432252B (it)
SU (1) SU1064868A3 (it)
ZA (1) ZA794627B (it)

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JP2753622B2 (ja) 1988-05-02 1998-05-20 大塚製薬株式会社 カルボスチリル誘導体
US5064837A (en) * 1989-11-13 1991-11-12 Schering Corporation 3-substituted-1-aryl-2(h)-quinolones and their pharmaceutical compositions
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US20030045547A1 (en) 2001-05-02 2003-03-06 Shinji Aki Process for producing carbostyril derivatives
JP4060523B2 (ja) * 1999-11-24 2008-03-12 大塚製薬株式会社 カルボスチリル誘導体の製造法
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US6458804B1 (en) 2001-01-26 2002-10-01 R.T. Alamo Venturesi, Llc Methods for the treatment of central nervous system disorders in certain patient groups
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US20050101631A1 (en) * 2002-08-01 2005-05-12 Otsuka Pharmaceuticals Company Process for producing carbostyril derivatives
US7399864B2 (en) * 2001-05-02 2008-07-15 Otsuka Pharmaceutical Co., Ltd. Process for producing carbostyril derivatives
JP2003063965A (ja) * 2001-06-13 2003-03-05 Otsuka Pharmaceut Factory Inc 注射用シロスタゾール水性製剤
US6573382B2 (en) * 2001-06-29 2003-06-03 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6596871B2 (en) * 2001-06-29 2003-07-22 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1h-tetraol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6657061B2 (en) * 2001-06-29 2003-12-02 Grayson Walker Stowell Polymorphic forms of 6-[4-1(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6388080B1 (en) 2001-06-29 2002-05-14 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6531603B1 (en) * 2001-06-29 2003-03-11 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
AU2002322456A1 (en) * 2001-06-29 2003-03-03 Aaipharma, Inc. Polymorphic forms of 6-(4-(1-cyclohexyl-1h-tetrazol-5-yl)butoxy)-3, 4-dihydro-2(1h)-quinolinone
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US6743806B2 (en) * 2002-10-23 2004-06-01 Otsuka Pharmaceutical Company, Limited Active oxygen scavenger
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ITMI20031670A1 (it) * 2003-08-26 2005-02-27 Dinamite Dipharma S P A In Forma A Bbreviata Diph Processo per la preparazione di cilostazolo e di suoi intermedi.
US7524960B2 (en) * 2004-03-16 2009-04-28 Chemagis Ltd. Highly pure cilostazol and an improved process for obtaining same
US20050255155A1 (en) * 2004-05-11 2005-11-17 Glenmark Pharmaceuticals Limited Modified release cilostazol compositions
US20080206348A1 (en) * 2004-09-17 2008-08-28 Deepak Murpani Cilostazol-Containing Pharmaceutical Composition Based On Particles Of Less Than 50 Micrometers
CN100462360C (zh) * 2005-08-15 2009-02-18 上海立科药物化学有限公司 N-环己基-5-(4-氯丁基)-1h-四氮唑的合成方法
PL1942895T3 (pl) 2005-09-15 2012-07-31 Otsuka Pharma Co Ltd Lek złożony zawierający probukol i pochodną tetrazoliloalkoksydihydrokarbostyrylu o działaniu hamującym nadtlenek
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TW200848041A (en) 2007-03-30 2008-12-16 Otsuka Pharma Co Ltd A medicament for treating schizophrenia comprising cilostazol
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Also Published As

Publication number Publication date
SE7907236L (sv) 1980-03-02
SU1064868A3 (ru) 1983-12-30
ES483792A1 (es) 1980-09-01
PT70136A (en) 1979-09-01
FI68398C (fi) 1985-09-10
MX6749E (es) 1986-06-25
NO153177B (no) 1985-10-21
NL183888C (nl) 1989-02-16
DK158788B (da) 1990-07-16
DE2934747C2 (it) 1988-01-28
AU538410B2 (en) 1984-08-16
AR229342A1 (es) 1983-07-29
DE2934747A1 (de) 1980-03-13
BE878548A (fr) 1979-12-17
AU5039779A (en) 1980-03-06
JPS5535019A (en) 1980-03-11
US4277479A (en) 1981-07-07
FR2434809B1 (it) 1982-09-17
FI68398B (fi) 1985-05-31
IT7968748A0 (it) 1979-08-31
AT364363B (de) 1981-10-12
ZA794627B (en) 1980-08-27
JPS6155514B2 (it) 1986-11-28
CA1139761A (en) 1983-01-18
NO792829L (no) 1980-03-04
DK158788C (da) 1990-12-10
ATA584579A (de) 1981-03-15
DK363179A (da) 1980-03-02
GB2033893B (en) 1982-12-01
GB2033893A (en) 1980-05-29
NL7906523A (nl) 1980-03-04
SE432252B (sv) 1984-03-26
NO153177C (no) 1986-01-29
FR2434809A1 (fr) 1980-03-28
CH641799A5 (de) 1984-03-15
FI792699A (fi) 1980-03-02
PH18452A (en) 1985-07-18

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Effective date: 19950831