AT364363B - Verfahren zum herstellen neuer tetrazolylalkoxycarbostyrilderivate - Google Patents

Verfahren zum herstellen neuer tetrazolylalkoxycarbostyrilderivate

Info

Publication number
AT364363B
AT364363B AT0584579A AT584579A AT364363B AT 364363 B AT364363 B AT 364363B AT 0584579 A AT0584579 A AT 0584579A AT 584579 A AT584579 A AT 584579A AT 364363 B AT364363 B AT 364363B
Authority
AT
Austria
Prior art keywords
alkoxycarbostyrile
tetrazolyl
derivatives
producing new
producing
Prior art date
Application number
AT0584579A
Other languages
English (en)
Other versions
ATA584579A (de
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=14470137&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AT364363(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of ATA584579A publication Critical patent/ATA584579A/de
Application granted granted Critical
Publication of AT364363B publication Critical patent/AT364363B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
AT0584579A 1978-09-01 1979-09-03 Verfahren zum herstellen neuer tetrazolylalkoxycarbostyrilderivate AT364363B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10786978A JPS5535019A (en) 1978-09-01 1978-09-01 Carbostyryl derivative

Publications (2)

Publication Number Publication Date
ATA584579A ATA584579A (de) 1981-03-15
AT364363B true AT364363B (de) 1981-10-12

Family

ID=14470137

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0584579A AT364363B (de) 1978-09-01 1979-09-03 Verfahren zum herstellen neuer tetrazolylalkoxycarbostyrilderivate

Country Status (23)

Country Link
US (1) US4277479A (de)
JP (1) JPS5535019A (de)
AR (1) AR229342A1 (de)
AT (1) AT364363B (de)
AU (1) AU538410B2 (de)
BE (1) BE878548A (de)
CA (1) CA1139761A (de)
CH (1) CH641799A5 (de)
DE (1) DE2934747A1 (de)
DK (1) DK158788C (de)
ES (1) ES483792A1 (de)
FI (1) FI68398C (de)
FR (1) FR2434809A1 (de)
GB (1) GB2033893B (de)
IT (1) IT1119929B (de)
MX (1) MX6749E (de)
NL (1) NL183888C (de)
NO (1) NO153177C (de)
PH (1) PH18452A (de)
PT (1) PT70136A (de)
SE (1) SE432252B (de)
SU (1) SU1064868A3 (de)
ZA (1) ZA794627B (de)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
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US4803162A (en) * 1984-05-15 1989-02-07 Fluorodiagnostic Limited Partners Composition, article and process for detecting a microorganism
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JPH0681752B2 (ja) * 1986-04-02 1994-10-19 大塚製薬株式会社 カルボスチリル誘導体
KR940000785B1 (ko) * 1986-04-02 1994-01-31 오오쓰까세이야꾸 가부시끼가이샤 카르보스티릴 유도체 및 그의 염의 제조 방법
DK167187A (da) * 1986-04-02 1987-10-03 Otsuka Pharma Co Ltd Carbostyrilderivater og salte deraf, fremgangsmaade til fremstilling af saadanne forbindelser og laegemiddel indeholdende disse
JP2753622B2 (ja) 1988-05-02 1998-05-20 大塚製薬株式会社 カルボスチリル誘導体
US5064837A (en) * 1989-11-13 1991-11-12 Schering Corporation 3-substituted-1-aryl-2(h)-quinolones and their pharmaceutical compositions
EP0463173B1 (de) * 1990-01-08 1994-12-07 Otsuka Pharmaceutical Co., Ltd. Zusammensetzung eines haartonikums sowie eines haarpflegemittels
TW201305B (de) * 1991-04-03 1993-03-01 Otsuka Pharma Co Ltd
KR930702307A (ko) * 1991-08-23 1993-09-08 오오쓰까 아끼히꼬 카르보스티릴 유도체 및 혈소판 응집 억제제
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US6187790B1 (en) 1999-03-04 2001-02-13 Neal R. Cutler Use of cilostazol for treatment of sexual dysfunction
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US6515128B2 (en) 2000-03-20 2003-02-04 Teva Pharmaceutical Industries Ltd. Processes for preparing cilostazol
KR20030024865A (ko) * 2000-08-14 2003-03-26 테바 파마슈티컬 인더스트리즈 리미티드 실로스타졸을 제조하는 방법
US6458804B1 (en) 2001-01-26 2002-10-01 R.T. Alamo Venturesi, Llc Methods for the treatment of central nervous system disorders in certain patient groups
US6451813B1 (en) 2001-01-26 2002-09-17 R. T. Alamo Ventures I, Llc Treatment of gastroparesis in certain patient groups
US20050101631A1 (en) * 2002-08-01 2005-05-12 Otsuka Pharmaceuticals Company Process for producing carbostyril derivatives
US7399864B2 (en) * 2001-05-02 2008-07-15 Otsuka Pharmaceutical Co., Ltd. Process for producing carbostyril derivatives
JP2003063965A (ja) * 2001-06-13 2003-03-05 Otsuka Pharmaceut Factory Inc 注射用シロスタゾール水性製剤
US6596871B2 (en) * 2001-06-29 2003-07-22 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1h-tetraol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
AU2002322456A1 (en) * 2001-06-29 2003-03-03 Aaipharma, Inc. Polymorphic forms of 6-(4-(1-cyclohexyl-1h-tetrazol-5-yl)butoxy)-3, 4-dihydro-2(1h)-quinolinone
US6531603B1 (en) * 2001-06-29 2003-03-11 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6657061B2 (en) * 2001-06-29 2003-12-02 Grayson Walker Stowell Polymorphic forms of 6-[4-1(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6660864B2 (en) * 2001-06-29 2003-12-09 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6573382B2 (en) * 2001-06-29 2003-06-03 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6388080B1 (en) 2001-06-29 2002-05-14 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
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US6743806B2 (en) * 2002-10-23 2004-06-01 Otsuka Pharmaceutical Company, Limited Active oxygen scavenger
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
TWI323660B (en) * 2003-02-25 2010-04-21 Otsuka Pharma Co Ltd Pten inhibitor or maxi-k channels opener
ITMI20031670A1 (it) * 2003-08-26 2005-02-27 Dinamite Dipharma S P A In Forma A Bbreviata Diph Processo per la preparazione di cilostazolo e di suoi intermedi.
IL167483A (en) * 2004-03-16 2011-04-28 Chemagis Ltd Process for obtaining highly pure cilostazol
US20050255155A1 (en) * 2004-05-11 2005-11-17 Glenmark Pharmaceuticals Limited Modified release cilostazol compositions
EP1802304A1 (de) * 2004-09-17 2007-07-04 Ranbaxy Laboratories Limited Pharmazeutische zusammensetzung mit cilostazol auf der basis von teilchen mit einer grösse von weniger als 50 mikrometern
CN100462360C (zh) * 2005-08-15 2009-02-18 上海立科药物化学有限公司 N-环己基-5-(4-氯丁基)-1h-四氮唑的合成方法
DK1942895T3 (da) 2005-09-15 2012-03-05 Otsuka Pharma Co Ltd Kombinationslægemiddel indeholdende probucol og et tetrazolylalkoxy-dihydrocarbostyrilderivat med superoxidhæmmende virkninger
US20070105898A1 (en) * 2005-11-09 2007-05-10 Apotex Pharmachem Inc. Process for the production of cilostazol
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US8349817B2 (en) * 2007-04-25 2013-01-08 Concert Pharmaceuticals, Inc. Analogues of cilostazol
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FI58329C (fi) * 1974-11-08 1981-01-12 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av i 8-staellning substituerade 5-(3'-alkylamino-2'-hydroxi)propoxi-3,4-dihydrokarbostyrilderivat
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JPS5430183A (en) * 1977-08-10 1979-03-06 Otsuka Pharmaceut Co Ltd 3,4-dihydrocarbostyril derivative

Also Published As

Publication number Publication date
AU538410B2 (en) 1984-08-16
DK363179A (da) 1980-03-02
US4277479A (en) 1981-07-07
NO792829L (no) 1980-03-04
IT7968748A0 (it) 1979-08-31
FI68398C (fi) 1985-09-10
NL183888C (nl) 1989-02-16
DE2934747A1 (de) 1980-03-13
SE432252B (sv) 1984-03-26
AR229342A1 (es) 1983-07-29
ES483792A1 (es) 1980-09-01
PT70136A (en) 1979-09-01
FI68398B (fi) 1985-05-31
CA1139761A (en) 1983-01-18
FR2434809B1 (de) 1982-09-17
PH18452A (en) 1985-07-18
NO153177C (no) 1986-01-29
DK158788B (da) 1990-07-16
SU1064868A3 (ru) 1983-12-30
NL7906523A (nl) 1980-03-04
ATA584579A (de) 1981-03-15
JPS5535019A (en) 1980-03-11
IT1119929B (it) 1986-03-19
JPS6155514B2 (de) 1986-11-28
GB2033893B (en) 1982-12-01
ZA794627B (en) 1980-08-27
FR2434809A1 (fr) 1980-03-28
GB2033893A (en) 1980-05-29
SE7907236L (sv) 1980-03-02
FI792699A (fi) 1980-03-02
MX6749E (es) 1986-06-25
NO153177B (no) 1985-10-21
DE2934747C2 (de) 1988-01-28
CH641799A5 (de) 1984-03-15
DK158788C (da) 1990-12-10
AU5039779A (en) 1980-03-06
BE878548A (fr) 1979-12-17

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