AT356108B - Verfahren zum herstellen von neuen spiro- piperidinverbindungen - Google Patents

Verfahren zum herstellen von neuen spiro- piperidinverbindungen

Info

Publication number
AT356108B
AT356108B AT388878A AT388878A AT356108B AT 356108 B AT356108 B AT 356108B AT 388878 A AT388878 A AT 388878A AT 388878 A AT388878 A AT 388878A AT 356108 B AT356108 B AT 356108B
Authority
AT
Austria
Prior art keywords
producing new
spiropiperidine compounds
spiropiperidine
compounds
producing
Prior art date
Application number
AT388878A
Other languages
English (en)
Other versions
ATA388878A (de
Original Assignee
Sumitomo Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co filed Critical Sumitomo Chemical Co
Publication of ATA388878A publication Critical patent/ATA388878A/de
Application granted granted Critical
Publication of AT356108B publication Critical patent/AT356108B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AT388878A 1978-02-13 1978-05-29 Verfahren zum herstellen von neuen spiro- piperidinverbindungen AT356108B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1577878A JPS54109983A (en) 1978-02-13 1978-02-13 Novel spiroamine derivative and its preparation

Publications (2)

Publication Number Publication Date
ATA388878A ATA388878A (de) 1979-09-15
AT356108B true AT356108B (de) 1980-04-10

Family

ID=11898262

Family Applications (1)

Application Number Title Priority Date Filing Date
AT388878A AT356108B (de) 1978-02-13 1978-05-29 Verfahren zum herstellen von neuen spiro- piperidinverbindungen

Country Status (13)

Country Link
US (1) US4233307A (de)
JP (1) JPS54109983A (de)
AT (1) AT356108B (de)
AU (1) AU511735B2 (de)
BE (1) BE867517A (de)
CA (1) CA1092106A (de)
CH (1) CH635841A5 (de)
DE (1) DE2822227A1 (de)
ES (1) ES470155A1 (de)
FR (1) FR2442845A1 (de)
IT (1) IT7849577A0 (de)
NL (1) NL7805814A (de)
SE (1) SE7805949L (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4337260A (en) * 1981-09-10 1982-06-29 Yoshitomi Pharmaceutical Industries, Ltd. Imidazopyridine-spiro-piperidine compounds
IL96507A0 (en) * 1989-12-08 1991-08-16 Merck & Co Inc Nitrogen-containing spirocycles and pharmaceutical compositions containing them
JPH08511522A (ja) * 1993-06-07 1996-12-03 メルク エンド カンパニー インコーポレーテッド ニューロキニンアンタゴニストとしてのスピロ置換アザ環
FR2724170B1 (fr) * 1994-09-02 1997-05-30 Cemaf Nouveaux derives de spiro(indole-pyrrolidine) agonistes de la melatonine, leur procede de preparation et leur utilisation a titre de medicament
EP0754183A1 (de) * 1994-04-07 1997-01-22 Cemaf Spiro [indole-pyrrolidin] derivate als melatonin agonisten,verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US5607936A (en) * 1994-09-30 1997-03-04 Merck & Co., Inc. Substituted aryl piperazines as neurokinin antagonists
US5962462A (en) * 1996-12-13 1999-10-05 Merck & Co., Inc. Spiro-substituted azacycles as modulators of chemokine receptor activity
US6013652A (en) * 1997-12-04 2000-01-11 Merck & Co., Inc. Spiro-substituted azacycles as neurokinin antagonists
SK822002A3 (en) * 1999-07-21 2002-09-10 Astrazeneca Ab New compounds
GB0213715D0 (en) 2002-06-14 2002-07-24 Syngenta Ltd Chemical compounds
EP1601674B1 (de) * 2002-09-09 2012-08-08 Janssen Pharmaceutica NV Hydroxyalkylsubstituierte 1,3,8-Triazaspiro[4.5]decan-4-on-Derivate zur Verwendung bei der Behandlung von Krankheiten, die mit dem ORL-1-Rezeptor in Zusammenhang stehen
JP2008510728A (ja) * 2004-08-19 2008-04-10 バーテックス ファーマシューティカルズ インコーポレイテッド ムスカリン受容体のモジュレーター
US7786141B2 (en) 2004-08-19 2010-08-31 Vertex Pharmaceuticals Incorporated Dihydrospiroindene modulators of muscarinic receptors
JP2008521825A (ja) * 2004-11-29 2008-06-26 バーテックス ファーマシューティカルズ インコーポレイテッド ムスカリン受容体のモジュレーター
AU2006252781A1 (en) * 2005-06-02 2006-12-07 Janssen Pharmaceutica, N.V. Novel 3-spirocyclic indolyl derivatives useful as ORL-1 receptor modulators
US8193208B2 (en) * 2005-09-09 2012-06-05 Purdue Pharma L.P. Fused and spirocycle compounds and the use thereof
CN101374519A (zh) * 2005-12-22 2009-02-25 弗特克斯药品有限公司 毒蕈碱性受体调节剂
JP2009527568A (ja) * 2006-02-22 2009-07-30 バーテックス ファーマシューティカルズ インコーポレイテッド ムスカリン受容体の調節剤
NZ570497A (en) * 2006-02-22 2011-09-30 Vertex Pharma Spiro condensed 4,4'-quinilino-piperidines derivatives as modulators of muscarinic receptors
EP2040706A2 (de) * 2006-06-29 2009-04-01 Vertex Pharmceuticals Incorporated Modulatoren muskarinischer rezeptoren
CN101553231A (zh) * 2006-08-15 2009-10-07 弗特克斯药品有限公司 毒蕈碱受体调节剂
JP2010501561A (ja) * 2006-08-18 2010-01-21 バーテックス ファーマシューティカルズ インコーポレイテッド ムスカリン受容体の調節剤
CN101622254B (zh) * 2006-11-28 2013-05-29 詹森药业有限公司 3-(3-氨基-2-(r)-羟基-丙基)-1-(4-氟-苯基)-8-(8-甲基-萘-1-基甲基)-1,3,8-三氮杂-螺[4.5]癸烷-4-酮的盐
CN101679430B (zh) * 2007-04-09 2013-12-25 詹森药业有限公司 用于治疗焦虑和抑郁症的作为orl-1受体的配体的1,3,8-三取代-1,3,8-三氮杂-螺[4.5]癸-4-酮衍生物
US20080306102A1 (en) * 2007-05-18 2008-12-11 Kowa Co., Ltd. Novel spirooxyindole compounds and drugs containing same
MX2010003373A (es) 2007-10-03 2010-04-30 Vertex Pharma Moduladores de receptores muscarinicos.
CA3248924A1 (en) * 2022-01-18 2023-07-27 Maze Therapeutics, Inc. APOL1 INHIBITORS AND METHODS OF USE
TW202510867A (zh) * 2023-07-17 2025-03-16 美商梅斯治療股份有限公司 Ａｐｏｌ１抑制劑及使用方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3299075A (en) * 1964-03-12 1967-01-17 Smith Kline French Lab Spiro [3h-indole-3, 3'-pyrrolidine and piperidine] derivatives

Also Published As

Publication number Publication date
ATA388878A (de) 1979-09-15
IT7849577A0 (it) 1978-05-26
DE2822227A1 (de) 1979-08-16
AU3616978A (en) 1979-11-22
SE7805949L (sv) 1979-08-14
JPS54109983A (en) 1979-08-29
CH635841A5 (de) 1983-04-29
FR2442845B1 (de) 1981-07-24
CA1092106A (en) 1980-12-23
BE867517A (fr) 1978-09-18
AU511735B2 (en) 1980-09-04
US4233307A (en) 1980-11-11
FR2442845A1 (fr) 1980-06-27
NL7805814A (nl) 1979-08-15
ES470155A1 (es) 1979-01-01

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
ELJ Ceased due to non-payment of the annual fee