SE7805949L - Spiroaminderivat och forfarande for framstellning derav och anvendning derav - Google Patents
Spiroaminderivat och forfarande for framstellning derav och anvendning deravInfo
- Publication number
- SE7805949L SE7805949L SE7805949A SE7805949A SE7805949L SE 7805949 L SE7805949 L SE 7805949L SE 7805949 A SE7805949 A SE 7805949A SE 7805949 A SE7805949 A SE 7805949A SE 7805949 L SE7805949 L SE 7805949L
- Authority
- SE
- Sweden
- Prior art keywords
- derivatives
- spiroamin
- procedures
- manufacture
- activity
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1577878A JPS54109983A (en) | 1978-02-13 | 1978-02-13 | Novel spiroamine derivative and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
SE7805949L true SE7805949L (sv) | 1979-08-14 |
Family
ID=11898262
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7805949A SE7805949L (sv) | 1978-02-13 | 1978-05-24 | Spiroaminderivat och forfarande for framstellning derav och anvendning derav |
Country Status (13)
Country | Link |
---|---|
US (1) | US4233307A (xx) |
JP (1) | JPS54109983A (xx) |
AT (1) | AT356108B (xx) |
AU (1) | AU511735B2 (xx) |
BE (1) | BE867517A (xx) |
CA (1) | CA1092106A (xx) |
CH (1) | CH635841A5 (xx) |
DE (1) | DE2822227A1 (xx) |
ES (1) | ES470155A1 (xx) |
FR (1) | FR2442845A1 (xx) |
IT (1) | IT7849577A0 (xx) |
NL (1) | NL7805814A (xx) |
SE (1) | SE7805949L (xx) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4337260A (en) * | 1981-09-10 | 1982-06-29 | Yoshitomi Pharmaceutical Industries, Ltd. | Imidazopyridine-spiro-piperidine compounds |
IL96507A0 (en) * | 1989-12-08 | 1991-08-16 | Merck & Co Inc | Nitrogen-containing spirocycles and pharmaceutical compositions containing them |
CA2163995A1 (en) * | 1993-06-07 | 1994-12-22 | Malcolm Maccoss | Spiro-substituted azacycles as neurokinin antagonists |
FR2724170B1 (fr) * | 1994-09-02 | 1997-05-30 | Cemaf | Nouveaux derives de spiro(indole-pyrrolidine) agonistes de la melatonine, leur procede de preparation et leur utilisation a titre de medicament |
CN1047386C (zh) * | 1994-04-07 | 1999-12-15 | 西玛夫公司 | 新型褪黑激素拮抗物螺旋[吲哚吡咯烷丁]衍生物,其制备方法及其作为药物产品的用途 |
US5607936A (en) * | 1994-09-30 | 1997-03-04 | Merck & Co., Inc. | Substituted aryl piperazines as neurokinin antagonists |
US5962462A (en) * | 1996-12-13 | 1999-10-05 | Merck & Co., Inc. | Spiro-substituted azacycles as modulators of chemokine receptor activity |
US6013652A (en) * | 1997-12-04 | 2000-01-11 | Merck & Co., Inc. | Spiro-substituted azacycles as neurokinin antagonists |
PL352911A1 (en) * | 1999-07-21 | 2003-09-22 | Astrazeneca Ab | New compounds |
GB0213715D0 (en) * | 2002-06-14 | 2002-07-24 | Syngenta Ltd | Chemical compounds |
MXPA05002622A (es) * | 2002-09-09 | 2005-09-08 | Johnson & Johnson | Derivados de 1,3,8,-triazaespiro [4.5]decan-4-ona sustituidos con hidroxialquilo utiles para el tratamiento de desordenes mediados por el receptor opioide huerfano. |
NZ553202A (en) | 2004-08-19 | 2010-12-24 | Vertex Pharma | Modulators of muscarinic receptors |
US7786141B2 (en) | 2004-08-19 | 2010-08-31 | Vertex Pharmaceuticals Incorporated | Dihydrospiroindene modulators of muscarinic receptors |
CN101155587A (zh) * | 2004-11-29 | 2008-04-02 | 弗特克斯药品有限公司 | 毒蕈碱受体调节剂 |
JP2008542375A (ja) * | 2005-06-02 | 2008-11-27 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | Orl−1受容体モジュレーターとして有用な新規3−スピロ環式インドリル誘導体 |
WO2007028638A1 (en) * | 2005-09-09 | 2007-03-15 | Euro-Celtique S.A. | Fused and spirocycle compounds and the use thereof |
CA2634456A1 (en) * | 2005-12-22 | 2007-07-05 | Vertex Pharmaceuticals Incorporated | Modulators of muscarinic receptors |
NZ570497A (en) * | 2006-02-22 | 2011-09-30 | Vertex Pharma | Spiro condensed 4,4'-quinilino-piperidines derivatives as modulators of muscarinic receptors |
EP1988892A2 (en) * | 2006-02-22 | 2008-11-12 | Vertex Pharmaceuticals Incorporated | Modulators of muscarinic receptors |
AU2007269863A1 (en) * | 2006-06-29 | 2008-01-10 | Vertex Pharmaceuticals Incorporated | Modulators of muscarinic receptors |
CN101553231A (zh) * | 2006-08-15 | 2009-10-07 | 弗特克斯药品有限公司 | 毒蕈碱受体调节剂 |
CA2660974A1 (en) * | 2006-08-18 | 2008-02-21 | Vertex Pharmaceuticals Incorporated | Modulators of muscarinic receptors |
MX2009005641A (es) * | 2006-11-28 | 2009-06-05 | Janssen Pharmaceutica Nv | Sales de 3-(3-amino-2-(r)-hidroxi-propil)-1-(4-fluoro-fenil)-8-(8- metil-naftalen-1-ilmetil)-1,3,8-triaza-espiro[4,5]deca n-4-ona. |
MX2009011006A (es) * | 2007-04-09 | 2009-11-02 | Janssen Pharmaceutica Nv | Derivados de 1,3,8-trisustituido-1,3,8-triaza-espiro[4.5]decano-4- ona como ligandos del receptor de orl-1 para el tratamiento de ansiedad y depresion. |
WO2008142859A1 (ja) * | 2007-05-18 | 2008-11-27 | Kowa Company, Ltd. | 新規なスピロオキシインドール化合物及びこれを含有する医薬 |
WO2009045519A1 (en) | 2007-10-03 | 2009-04-09 | Vertex Pharmaceuticals Incorporated | Modulators of muscarinic receptors |
US11976067B2 (en) * | 2022-01-18 | 2024-05-07 | Maze Therapeutics, Inc. | APOL1 inhibitors and methods of use |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3299075A (en) * | 1964-03-12 | 1967-01-17 | Smith Kline French Lab | Spiro [3h-indole-3, 3'-pyrrolidine and piperidine] derivatives |
-
1978
- 1978-02-13 JP JP1577878A patent/JPS54109983A/ja active Pending
- 1978-05-16 AU AU36169/78A patent/AU511735B2/en not_active Expired
- 1978-05-22 DE DE19782822227 patent/DE2822227A1/de not_active Withdrawn
- 1978-05-24 ES ES470155A patent/ES470155A1/es not_active Expired
- 1978-05-24 CH CH566278A patent/CH635841A5/de not_active IP Right Cessation
- 1978-05-24 SE SE7805949A patent/SE7805949L/xx not_active Application Discontinuation
- 1978-05-25 FR FR7815606A patent/FR2442845A1/fr active Granted
- 1978-05-26 IT IT7849577A patent/IT7849577A0/it unknown
- 1978-05-26 BE BE188062A patent/BE867517A/xx not_active IP Right Cessation
- 1978-05-29 CA CA304,287A patent/CA1092106A/en not_active Expired
- 1978-05-29 AT AT388878A patent/AT356108B/de not_active IP Right Cessation
- 1978-05-29 NL NL7805814A patent/NL7805814A/xx not_active Application Discontinuation
- 1978-05-30 US US05/910,537 patent/US4233307A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU3616978A (en) | 1979-11-22 |
JPS54109983A (en) | 1979-08-29 |
FR2442845B1 (xx) | 1981-07-24 |
AT356108B (de) | 1980-04-10 |
NL7805814A (nl) | 1979-08-15 |
DE2822227A1 (de) | 1979-08-16 |
BE867517A (fr) | 1978-09-18 |
ES470155A1 (es) | 1979-01-01 |
FR2442845A1 (fr) | 1980-06-27 |
AU511735B2 (en) | 1980-09-04 |
ATA388878A (de) | 1979-09-15 |
IT7849577A0 (it) | 1978-05-26 |
CA1092106A (en) | 1980-12-23 |
CH635841A5 (de) | 1983-04-29 |
US4233307A (en) | 1980-11-11 |
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