AR211006A1 - Procedimiento para preparar nuevos derivados de la 2-hidroxi-4-flourobutiprofenona depresores del sistema nervioso central. - Google Patents
Procedimiento para preparar nuevos derivados de la 2-hidroxi-4-flourobutiprofenona depresores del sistema nervioso central.Info
- Publication number
- AR211006A1 AR211006A1 AR262454A AR26245476A AR211006A1 AR 211006 A1 AR211006 A1 AR 211006A1 AR 262454 A AR262454 A AR 262454A AR 26245476 A AR26245476 A AR 26245476A AR 211006 A1 AR211006 A1 AR 211006A1
- Authority
- AR
- Argentina
- Prior art keywords
- flourobutiprofenone
- depressors
- hydroxy
- procedure
- nervous system
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
- C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP50027489A JPS51125239A (en) | 1975-03-05 | 1975-03-05 | Process for preparing new bytyrophenone derivatives |
| JP50138836A JPS596304B2 (ja) | 1975-11-18 | 1975-11-18 | シンキナブチロフエノンユウドウタイノセイホウ |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR211006A1 true AR211006A1 (es) | 1977-10-14 |
Family
ID=26365419
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR262454A AR211006A1 (es) | 1975-03-05 | 1976-03-05 | Procedimiento para preparar nuevos derivados de la 2-hidroxi-4-flourobutiprofenona depresores del sistema nervioso central. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4235914A (es) |
| AR (1) | AR211006A1 (es) |
| AT (1) | AT346341B (es) |
| AU (1) | AU503943B2 (es) |
| BE (1) | BE839097A (es) |
| CA (1) | CA1077039A (es) |
| CH (1) | CH611598A5 (es) |
| CS (1) | CS188131B2 (es) |
| DD (1) | DD124116A5 (es) |
| DE (1) | DE2608801A1 (es) |
| DK (1) | DK93976A (es) |
| ES (1) | ES445775A1 (es) |
| FI (1) | FI60390C (es) |
| FR (1) | FR2302728A1 (es) |
| GB (1) | GB1506805A (es) |
| HU (1) | HU175175B (es) |
| MX (1) | MX3392E (es) |
| NL (1) | NL7602370A (es) |
| PL (1) | PL106528B1 (es) |
| SE (1) | SE7602049L (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4894461A (en) * | 1981-04-27 | 1990-01-16 | Hoechst-Roussel Pharmaceuticals, Inc. | 3-(γ-chloropropyl)-6-fluoro-1,2-benzisoxazole |
| US4396770A (en) * | 1982-04-09 | 1983-08-02 | Hoechst-Roussel Pharmaceuticals Inc. | 1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-hydroxy-4-phenylpiperidines |
| US4390544A (en) * | 1982-04-09 | 1983-06-28 | Hoechst-Roussel Pharmaceuticals Inc. | {1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(2-oxo-1-benzimidazolinyl}p |
| US4610988A (en) * | 1982-04-09 | 1986-09-09 | Hoechst-Roussel Pharmaceuticals Inc. | 1-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines useful for alleviating pain |
| US4536578A (en) * | 1982-04-09 | 1985-08-20 | Hoechst-Roussel Pharmaceuticals Inc. | 1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines |
| US4374245A (en) * | 1982-04-09 | 1983-02-15 | Hoechst-Roussel Pharmaceuticals Inc. | 8-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one |
| IL66866A (en) * | 1982-04-09 | 1987-08-31 | Hoechst Roussel Pharma | 1-(3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl)-4-(substituted)-piperazines and-piperidines,a process for the preparation thereof,and pharmaceutical compositions containing them |
| US4458075A (en) * | 1982-04-09 | 1984-07-03 | Hoechst-Roussel Pharmaceuticals Inc. | 6-Fluoro-3-[3-(1-heterocyclo)propyl]-1,2-benzisoxazoles |
| US4609658A (en) * | 1982-04-09 | 1986-09-02 | Hoechst-Roussel Pharmaceuticals Inc. | 1-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted) piperazines useful for reducing blood pressure |
| US4420485A (en) * | 1982-09-29 | 1983-12-13 | Hoechst-Roussel Pharmaceuticals Inc. | 1'-[3-(1,2-Benzisoxazol-3-yl) proply]spiro[benzofuran-2(3H),3' or 4'-piperidines or 3'-pyrrolidines] |
| KR910006138B1 (ko) * | 1986-09-30 | 1991-08-16 | 에자이 가부시끼가이샤 | 환상아민 유도체 |
| EP0661266A1 (en) * | 1993-12-27 | 1995-07-05 | Toa Eiyo Ltd. | Substituted cyclic amine compounds as 5HT2 antagonists |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3799932A (en) * | 1970-03-20 | 1974-03-26 | Sumitomo Chemical Co | Gamma-piperidinobutyrophenones |
| JPS4718878U (es) * | 1971-04-05 | 1972-11-02 | ||
| JPS5755714B2 (es) * | 1972-03-18 | 1982-11-25 |
-
1976
- 1976-02-19 FI FI760415A patent/FI60390C/fi not_active IP Right Cessation
- 1976-02-20 SE SE7602049A patent/SE7602049L/xx not_active Application Discontinuation
- 1976-02-27 CS CS761296A patent/CS188131B2/cs unknown
- 1976-03-02 GB GB8171/76A patent/GB1506805A/en not_active Expired
- 1976-03-02 BE BE164777A patent/BE839097A/xx not_active IP Right Cessation
- 1976-03-02 CA CA246,882A patent/CA1077039A/en not_active Expired
- 1976-03-03 AT AT155776A patent/AT346341B/de not_active IP Right Cessation
- 1976-03-03 FR FR7606032A patent/FR2302728A1/fr active Granted
- 1976-03-03 DE DE19762608801 patent/DE2608801A1/de not_active Withdrawn
- 1976-03-03 CH CH265176A patent/CH611598A5/xx not_active IP Right Cessation
- 1976-03-04 ES ES445775A patent/ES445775A1/es not_active Expired
- 1976-03-04 DK DK93976*#A patent/DK93976A/da not_active Application Discontinuation
- 1976-03-04 MX MX000037U patent/MX3392E/es unknown
- 1976-03-05 AU AU11730/76A patent/AU503943B2/en not_active Ceased
- 1976-03-05 HU HU76SU911A patent/HU175175B/hu unknown
- 1976-03-05 AR AR262454A patent/AR211006A1/es active
- 1976-03-05 NL NL7602370A patent/NL7602370A/xx not_active Application Discontinuation
- 1976-03-05 DD DD191722A patent/DD124116A5/xx unknown
- 1976-03-05 PL PL1976187731A patent/PL106528B1/pl unknown
-
1978
- 1978-10-17 US US05/952,104 patent/US4235914A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| FR2302728B1 (es) | 1979-10-05 |
| DE2608801A1 (de) | 1976-09-16 |
| HU175175B (hu) | 1980-05-28 |
| CS188131B2 (en) | 1979-02-28 |
| AT346341B (de) | 1978-11-10 |
| CA1077039A (en) | 1980-05-06 |
| PL106528B1 (pl) | 1979-12-31 |
| MX3392E (es) | 1980-10-28 |
| NL7602370A (nl) | 1976-09-07 |
| FI60390B (fi) | 1981-09-30 |
| FI60390C (fi) | 1982-01-11 |
| GB1506805A (en) | 1978-04-12 |
| DD124116A5 (es) | 1977-02-02 |
| DK93976A (da) | 1976-09-06 |
| ATA155776A (de) | 1978-03-15 |
| FR2302728A1 (fr) | 1976-10-01 |
| AU503943B2 (en) | 1979-09-27 |
| ES445775A1 (es) | 1977-10-16 |
| US4235914A (en) | 1980-11-25 |
| BE839097A (fr) | 1976-09-02 |
| FI760415A (es) | 1976-09-06 |
| AU1173076A (en) | 1977-09-08 |
| CH611598A5 (es) | 1979-06-15 |
| SE7602049L (sv) | 1976-09-06 |
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