FI66853C - Mellanprodukt foer anvaendning vid framstaellning av hypotensivt 2-(4-(2-furoyl)piperazin-1-yl)-6,7-dimetoxikinazolin - Google Patents

Mellanprodukt foer anvaendning vid framstaellning av hypotensivt 2-(4-(2-furoyl)piperazin-1-yl)-6,7-dimetoxikinazolin Download PDF

Info

Publication number
FI66853C
FI66853C FI771741A FI771741A FI66853C FI 66853 C FI66853 C FI 66853C FI 771741 A FI771741 A FI 771741A FI 771741 A FI771741 A FI 771741A FI 66853 C FI66853 C FI 66853C
Authority
FI
Finland
Prior art keywords
formula
compound
reaction
furoyl
piperazin
Prior art date
Application number
FI771741A
Other languages
English (en)
Finnish (fi)
Other versions
FI66853B (fi
FI771741A (xx
Inventor
Philip Dietrich Hammen
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI771741A publication Critical patent/FI771741A/fi
Application granted granted Critical
Publication of FI66853B publication Critical patent/FI66853B/fi
Publication of FI66853C publication Critical patent/FI66853C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI771741A 1976-06-15 1977-06-01 Mellanprodukt foer anvaendning vid framstaellning av hypotensivt 2-(4-(2-furoyl)piperazin-1-yl)-6,7-dimetoxikinazolin FI66853C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69620176A 1976-06-15 1976-06-15
US69620176 1976-06-15

Publications (3)

Publication Number Publication Date
FI771741A FI771741A (xx) 1977-12-16
FI66853B FI66853B (fi) 1984-08-31
FI66853C true FI66853C (fi) 1984-12-10

Family

ID=24796111

Family Applications (1)

Application Number Title Priority Date Filing Date
FI771741A FI66853C (fi) 1976-06-15 1977-06-01 Mellanprodukt foer anvaendning vid framstaellning av hypotensivt 2-(4-(2-furoyl)piperazin-1-yl)-6,7-dimetoxikinazolin

Country Status (34)

Country Link
JP (1) JPS52153985A (xx)
AR (1) AR218251A1 (xx)
AT (1) AT356115B (xx)
BE (1) BE855656A (xx)
BG (3) BG35747A3 (xx)
CA (1) CA1068698A (xx)
CH (3) CH638203A5 (xx)
CS (1) CS202069B2 (xx)
DD (1) DD131021A5 (xx)
DE (1) DE2725019A1 (xx)
DK (1) DK146625C (xx)
EG (1) EG12922A (xx)
ES (1) ES459364A1 (xx)
FI (1) FI66853C (xx)
FR (1) FR2355015A1 (xx)
GB (1) GB1548856A (xx)
GR (1) GR72288B (xx)
HK (1) HK31481A (xx)
HU (1) HU177883B (xx)
IE (1) IE45423B1 (xx)
IL (1) IL52167A (xx)
LU (1) LU77530A1 (xx)
MY (1) MY8100270A (xx)
NL (1) NL172543C (xx)
NO (1) NO147838C (xx)
NZ (1) NZ184168A (xx)
PH (1) PH22196A (xx)
PL (3) PL111221B1 (xx)
PT (1) PT66617B (xx)
RO (3) RO77330A (xx)
SE (2) SE435380B (xx)
SU (2) SU1033002A3 (xx)
YU (1) YU40164B (xx)
ZA (1) ZA773014B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3346675A1 (de) * 1983-12-23 1985-07-04 Beiersdorf Ag, 2000 Hamburg Substituierte 1-(4-amino-6,7-dialkoxy-chinazolinyl)-4- cyclohexenyl-derivate des piperazins und homopiperazins, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen und zwischenprodukte
AT384218B (de) * 1985-12-04 1987-10-12 Gerot Pharmazeutika Verfahren zur herstellung von neuen chinazolin-derivaten
CA2077252C (en) * 1992-08-31 2001-04-10 Khashayar Karimian Methods of making ureas and guanidines, and intermediates therefor
IL112249A (en) 1994-01-25 2001-11-25 Warner Lambert Co Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds
US5654307A (en) * 1994-01-25 1997-08-05 Warner-Lambert Company Bicyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
IL112248A0 (en) 1994-01-25 1995-03-30 Warner Lambert Co Tricyclic heteroaromatic compounds and pharmaceutical compositions containing them
US5932538A (en) * 1996-02-02 1999-08-03 Nitromed, Inc. Nitrosated and nitrosylated α-adrenergic receptor antagonist compounds, compositions and their uses

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3511836A (en) 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
US3669968A (en) 1970-05-21 1972-06-13 Pfizer Trialkoxy quinazolines
JPS4966691A (xx) * 1972-10-30 1974-06-27
US3935213A (en) 1973-12-05 1976-01-27 Pfizer Inc. Process for hypotensive 4-amino-2-(piperazin-1-yl) quinazoline derivatives
JPS50126682A (xx) * 1974-03-25 1975-10-04

Also Published As

Publication number Publication date
LU77530A1 (fr) 1979-03-26
SU946402A3 (ru) 1982-07-23
PL111221B1 (en) 1980-08-30
NO147838B (no) 1983-03-14
SU1033002A3 (ru) 1983-07-30
RO77308A (ro) 1981-08-17
SE450120B (sv) 1987-06-09
SE8107554L (sv) 1981-12-16
YU132677A (en) 1982-08-31
NL172543B (nl) 1983-04-18
FI66853B (fi) 1984-08-31
PL198874A1 (pl) 1978-04-10
CA1068698A (en) 1979-12-25
NL7705939A (nl) 1977-12-19
JPS52153985A (en) 1977-12-21
AU2558377A (en) 1978-09-07
PT66617A (en) 1977-06-01
ES459364A1 (es) 1978-03-16
BG35748A3 (en) 1984-06-15
SE7705745L (sv) 1977-12-16
FR2355015A1 (fr) 1978-01-13
PL113012B1 (en) 1980-11-29
DK240877A (da) 1977-12-16
FI771741A (xx) 1977-12-16
RO73050A (ro) 1981-08-30
CH638516A5 (en) 1983-09-30
CH638203A5 (en) 1983-09-15
DK146625B (da) 1983-11-21
FR2355015B1 (xx) 1981-07-24
NO147838C (no) 1983-06-22
NZ184168A (en) 1979-08-31
DK146625C (da) 1984-06-04
HK31481A (en) 1981-07-10
GB1548856A (en) 1979-07-18
IL52167A0 (en) 1977-07-31
MY8100270A (en) 1981-12-31
ZA773014B (en) 1978-04-26
IL52167A (en) 1981-01-30
GR72288B (xx) 1983-10-17
CS202069B2 (en) 1980-12-31
AR218251A1 (es) 1980-05-30
HU177883B (en) 1982-01-28
BG35594A3 (en) 1984-05-15
SE435380B (sv) 1984-09-24
ATA386977A (de) 1979-09-15
JPS5543465B2 (xx) 1980-11-06
YU40164B (en) 1985-08-31
PH22196A (en) 1988-06-28
BE855656A (fr) 1977-12-14
NO771919L (no) 1977-12-16
IE45423L (en) 1977-12-15
NL172543C (nl) 1983-09-16
IE45423B1 (en) 1982-08-25
BG35747A3 (en) 1984-06-15
PT66617B (en) 1978-10-27
RO77330A (ro) 1981-06-22
CH638517A5 (en) 1983-09-30
EG12922A (en) 1980-03-31
AT356115B (de) 1980-04-10
DE2725019A1 (de) 1977-12-22
PL105558B1 (pl) 1979-10-31
DD131021A5 (de) 1978-05-24

Similar Documents

Publication Publication Date Title
FI59799B (fi) Nytt foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-piperazin-1-yl)-kinazolin foer anvaendning som ett antihypertensivt medel
US5990311A (en) Process for preparation of pyrimidine derivatives
SK11982003A3 (sk) Spôsob výroby 4,6-diaminopyrimido[5,4-d]pyrimidínov a medziprodukty
FI66853C (fi) Mellanprodukt foer anvaendning vid framstaellning av hypotensivt 2-(4-(2-furoyl)piperazin-1-yl)-6,7-dimetoxikinazolin
AU644295B2 (en) 2-aminopyrimidine-4-carboxamide derivatives, their preparation and their use in therapeutics
US5391737A (en) Process for the preparation of 6,7-dichloro-1,5-dihydroimidazo[2,1-b]quinazolin-2[3H]-one
KR100573859B1 (ko) 9-[4-아세톡시-3-(아세톡시메틸)부트-1-일]-2-아미노푸린의제조방법
US4650892A (en) Process for the preparation of herbicidal sulfonamides
US4638075A (en) Herbicidal sulfonamides
SK282234B6 (sk) Spôsob výroby n-metyl-3-(1-metyl-4-piperidinyl)-1h-indol-5-etánsulfónamidu a medziprodukt
US20020061919A1 (en) Process for the preparation of 1,2,3,9-tetrahydro-9-methyl-3-{(2-methyl-1h-imidazol-1-yl)methyl}-4h-carbazol-4-one
US4217452A (en) Synthesis for the preparation of tetracyclic compounds
US5053513A (en) Method of reducing a carbonyl containing acridine
SU999967A3 (ru) Способ получени 6-N-замещенных 6-амино-3-пиридазинилгидразинов или их солей
EP0199485B1 (en) Intermediates and process
US4423219A (en) Production of purine derivatives and intermediates therefor
KR810000293B1 (ko) 치환아미노 퀴나졸린 유도체의 제조방법
FR2769912A1 (fr) Nouveaux derives de la 3-oxo- (2h)-1,2,4 triazine leur preparation et leur application en therapeutique humaine
KR100368895B1 (ko) 1,2,3,9-테트라하이드로-9-메틸-3-[(2-메틸-1ｈ-이미다졸-1-일)메틸]-4ｈ-카바졸-4-온의 제조방법
CS202071B2 (cs) Způsob přípravy 2-(4-substituovaných piperazin-1-yl)-4-amino-6,7- -dimethoxychinazolinů
HU198179B (en) Process for producing n-methyl-1-alkylthio-2-nitroethenamine derivatives
HU190728B (en) Process for preparing pyrazolo/3,4-b/quinoline derivatives
DK141626B (da) Fremgangsmåde til fremstilling af quinazoliner.
FI65999C (fi) Foerfarande foer framstaellning av 2-(4-(2-furoyl)piperazin-1-yl)-4-amino-6,7-dimetoxikinazolin och en mellanprodukt foer anvaendning vid foerfarandet
Barluenga et al. Synthesis of halogenated hydrazone derivatives and their applicability in the preparation of 4‐chloropyrazoles

Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: PFIZER INC.