SE8107554L - Nya substituerade dimetoxikinazolinderivat - Google Patents

Nya substituerade dimetoxikinazolinderivat

Info

Publication number
SE8107554L
SE8107554L SE8107554A SE8107554A SE8107554L SE 8107554 L SE8107554 L SE 8107554L SE 8107554 A SE8107554 A SE 8107554A SE 8107554 A SE8107554 A SE 8107554A SE 8107554 L SE8107554 L SE 8107554L
Authority
SE
Sweden
Prior art keywords
carbon atoms
dimetoxicinazoline
derivatives
dimethoxyquinazoline
compounds
Prior art date
Application number
SE8107554A
Other languages
English (en)
Other versions
SE450120B (sv
Inventor
P D Hammen
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of SE8107554L publication Critical patent/SE8107554L/sv
Publication of SE450120B publication Critical patent/SE450120B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Claims (1)

1. RATHNTKRAV 1, Intermediatfbrening for anvEndning yid framstEllning ay ett hYPotensivt medal, som her formeln vari X Er klor eller brom, R3 Er vate och R4 Er -000cH2c6H4 -00126, -000R2, -CEO eller -COON eller R3 och R4 tillsammant med den kvaveatom vartill de Er banana bildar en ftalimidograPP; Rs Er vate, klor, brom, metyl, metoxi eller nitro cot R, Er alkyl med 1-4 kolatomer eller -C6R4R5, saint syraadditionssalter darav. —(11 /e----\ /N-R 2 vari R2 Er furoyl, kannetecknaddarav, att den har formeln CR30
SE8107554A 1976-06-15 1981-12-16 Nya dimetoxikinazolinderivat till anvendning for framstellning av 2(4-substituerade piperazin-1-yl)-4-amino-6,7-dimetoxikinazoliner SE450120B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69620176A 1976-06-15 1976-06-15

Publications (2)

Publication Number Publication Date
SE8107554L true SE8107554L (sv) 1981-12-16
SE450120B SE450120B (sv) 1987-06-09

Family

ID=24796111

Family Applications (2)

Application Number Title Priority Date Filing Date
SE7705745A SE435380B (sv) 1976-06-15 1977-05-16 Forfarande for framstellning av kinazolinforeningar
SE8107554A SE450120B (sv) 1976-06-15 1981-12-16 Nya dimetoxikinazolinderivat till anvendning for framstellning av 2(4-substituerade piperazin-1-yl)-4-amino-6,7-dimetoxikinazoliner

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SE7705745A SE435380B (sv) 1976-06-15 1977-05-16 Forfarande for framstellning av kinazolinforeningar

Country Status (34)

Country Link
JP (1) JPS52153985A (sv)
AR (1) AR218251A1 (sv)
AT (1) AT356115B (sv)
BE (1) BE855656A (sv)
BG (3) BG35748A3 (sv)
CA (1) CA1068698A (sv)
CH (3) CH638203A5 (sv)
CS (1) CS202069B2 (sv)
DD (1) DD131021A5 (sv)
DE (1) DE2725019A1 (sv)
DK (1) DK146625C (sv)
EG (1) EG12922A (sv)
ES (1) ES459364A1 (sv)
FI (1) FI66853C (sv)
FR (1) FR2355015A1 (sv)
GB (1) GB1548856A (sv)
GR (1) GR72288B (sv)
HK (1) HK31481A (sv)
HU (1) HU177883B (sv)
IE (1) IE45423B1 (sv)
IL (1) IL52167A (sv)
LU (1) LU77530A1 (sv)
MY (1) MY8100270A (sv)
NL (1) NL172543C (sv)
NO (1) NO147838C (sv)
NZ (1) NZ184168A (sv)
PH (1) PH22196A (sv)
PL (3) PL111221B1 (sv)
PT (1) PT66617B (sv)
RO (3) RO77330A (sv)
SE (2) SE435380B (sv)
SU (2) SU1033002A3 (sv)
YU (1) YU40164B (sv)
ZA (1) ZA773014B (sv)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3346675A1 (de) * 1983-12-23 1985-07-04 Beiersdorf Ag, 2000 Hamburg Substituierte 1-(4-amino-6,7-dialkoxy-chinazolinyl)-4- cyclohexenyl-derivate des piperazins und homopiperazins, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen und zwischenprodukte
AT384218B (de) * 1985-12-04 1987-10-12 Gerot Pharmazeutika Verfahren zur herstellung von neuen chinazolin-derivaten
CA2077252C (en) * 1992-08-31 2001-04-10 Khashayar Karimian Methods of making ureas and guanidines, and intermediates therefor
US5679683A (en) * 1994-01-25 1997-10-21 Warner-Lambert Company Tricyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
IL112249A (en) 1994-01-25 2001-11-25 Warner Lambert Co Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds
IL112248A0 (en) 1994-01-25 1995-03-30 Warner Lambert Co Tricyclic heteroaromatic compounds and pharmaceutical compositions containing them
US5932538A (en) * 1996-02-02 1999-08-03 Nitromed, Inc. Nitrosated and nitrosylated α-adrenergic receptor antagonist compounds, compositions and their uses

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3511836A (en) 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
US3669968A (en) 1970-05-21 1972-06-13 Pfizer Trialkoxy quinazolines
JPS4966691A (sv) * 1972-10-30 1974-06-27
US3935213A (en) 1973-12-05 1976-01-27 Pfizer Inc. Process for hypotensive 4-amino-2-(piperazin-1-yl) quinazoline derivatives
JPS50126682A (sv) * 1974-03-25 1975-10-04

Also Published As

Publication number Publication date
JPS5543465B2 (sv) 1980-11-06
PT66617B (en) 1978-10-27
SU946402A3 (ru) 1982-07-23
CH638203A5 (en) 1983-09-15
CS202069B2 (en) 1980-12-31
PL105558B1 (pl) 1979-10-31
NZ184168A (en) 1979-08-31
FR2355015A1 (fr) 1978-01-13
YU40164B (en) 1985-08-31
PL198874A1 (pl) 1978-04-10
LU77530A1 (fr) 1979-03-26
EG12922A (en) 1980-03-31
RO77308A (ro) 1981-08-17
DD131021A5 (de) 1978-05-24
HU177883B (en) 1982-01-28
PL111221B1 (en) 1980-08-30
AT356115B (de) 1980-04-10
BE855656A (fr) 1977-12-14
NO147838B (no) 1983-03-14
CH638517A5 (en) 1983-09-30
SE435380B (sv) 1984-09-24
FR2355015B1 (sv) 1981-07-24
DK240877A (da) 1977-12-16
GB1548856A (en) 1979-07-18
NO771919L (no) 1977-12-16
CH638516A5 (en) 1983-09-30
HK31481A (en) 1981-07-10
MY8100270A (en) 1981-12-31
IE45423B1 (en) 1982-08-25
IL52167A (en) 1981-01-30
ATA386977A (de) 1979-09-15
DE2725019A1 (de) 1977-12-22
PH22196A (en) 1988-06-28
FI771741A (sv) 1977-12-16
ZA773014B (en) 1978-04-26
AR218251A1 (es) 1980-05-30
PL113012B1 (en) 1980-11-29
SE7705745L (sv) 1977-12-16
YU132677A (en) 1982-08-31
NL7705939A (nl) 1977-12-19
BG35594A3 (en) 1984-05-15
IE45423L (en) 1977-12-15
NO147838C (no) 1983-06-22
RO73050A (ro) 1981-08-30
NL172543C (nl) 1983-09-16
FI66853C (fi) 1984-12-10
SU1033002A3 (ru) 1983-07-30
GR72288B (sv) 1983-10-17
NL172543B (nl) 1983-04-18
ES459364A1 (es) 1978-03-16
AU2558377A (en) 1978-09-07
JPS52153985A (en) 1977-12-21
CA1068698A (en) 1979-12-25
DK146625B (da) 1983-11-21
PT66617A (en) 1977-06-01
RO77330A (ro) 1981-06-22
DK146625C (da) 1984-06-04
BG35747A3 (en) 1984-06-15
FI66853B (fi) 1984-08-31
IL52167A0 (en) 1977-07-31
BG35748A3 (en) 1984-06-15
SE450120B (sv) 1987-06-09

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