HU177883B - Process for preparing 2-/4-/2-furoyl/-piperazin-1-yl/-4-amino-6,7-dimethoxy-quinazoline - Google Patents

Process for preparing 2-/4-/2-furoyl/-piperazin-1-yl/-4-amino-6,7-dimethoxy-quinazoline

Info

Publication number
HU177883B
HU177883B HU77PI578A HUPI000578A HU177883B HU 177883 B HU177883 B HU 177883B HU 77PI578 A HU77PI578 A HU 77PI578A HU PI000578 A HUPI000578 A HU PI000578A HU 177883 B HU177883 B HU 177883B
Authority
HU
Hungary
Prior art keywords
furoyl
quinazoline
piperazin
dimethoxy
amino
Prior art date
Application number
HU77PI578A
Other languages
English (en)
Inventor
Philip D Hammen
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of HU177883B publication Critical patent/HU177883B/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HU77PI578A 1976-06-15 1977-06-14 Process for preparing 2-/4-/2-furoyl/-piperazin-1-yl/-4-amino-6,7-dimethoxy-quinazoline HU177883B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69620176A 1976-06-15 1976-06-15

Publications (1)

Publication Number Publication Date
HU177883B true HU177883B (en) 1982-01-28

Family

ID=24796111

Family Applications (1)

Application Number Title Priority Date Filing Date
HU77PI578A HU177883B (en) 1976-06-15 1977-06-14 Process for preparing 2-/4-/2-furoyl/-piperazin-1-yl/-4-amino-6,7-dimethoxy-quinazoline

Country Status (34)

Country Link
JP (1) JPS52153985A (hu)
AR (1) AR218251A1 (hu)
AT (1) AT356115B (hu)
BE (1) BE855656A (hu)
BG (3) BG35748A3 (hu)
CA (1) CA1068698A (hu)
CH (3) CH638203A5 (hu)
CS (1) CS202069B2 (hu)
DD (1) DD131021A5 (hu)
DE (1) DE2725019A1 (hu)
DK (1) DK146625C (hu)
EG (1) EG12922A (hu)
ES (1) ES459364A1 (hu)
FI (1) FI66853C (hu)
FR (1) FR2355015A1 (hu)
GB (1) GB1548856A (hu)
GR (1) GR72288B (hu)
HK (1) HK31481A (hu)
HU (1) HU177883B (hu)
IE (1) IE45423B1 (hu)
IL (1) IL52167A (hu)
LU (1) LU77530A1 (hu)
MY (1) MY8100270A (hu)
NL (1) NL172543C (hu)
NO (1) NO147838C (hu)
NZ (1) NZ184168A (hu)
PH (1) PH22196A (hu)
PL (3) PL111221B1 (hu)
PT (1) PT66617B (hu)
RO (3) RO77330A (hu)
SE (2) SE435380B (hu)
SU (2) SU1033002A3 (hu)
YU (1) YU40164B (hu)
ZA (1) ZA773014B (hu)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3346675A1 (de) * 1983-12-23 1985-07-04 Beiersdorf Ag, 2000 Hamburg Substituierte 1-(4-amino-6,7-dialkoxy-chinazolinyl)-4- cyclohexenyl-derivate des piperazins und homopiperazins, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen und zwischenprodukte
AT384218B (de) * 1985-12-04 1987-10-12 Gerot Pharmazeutika Verfahren zur herstellung von neuen chinazolin-derivaten
CA2077252C (en) * 1992-08-31 2001-04-10 Khashayar Karimian Methods of making ureas and guanidines, and intermediates therefor
US5679683A (en) * 1994-01-25 1997-10-21 Warner-Lambert Company Tricyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
IL112249A (en) 1994-01-25 2001-11-25 Warner Lambert Co Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds
IL112248A0 (en) 1994-01-25 1995-03-30 Warner Lambert Co Tricyclic heteroaromatic compounds and pharmaceutical compositions containing them
US5932538A (en) * 1996-02-02 1999-08-03 Nitromed, Inc. Nitrosated and nitrosylated α-adrenergic receptor antagonist compounds, compositions and their uses

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3511836A (en) 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
US3669968A (en) 1970-05-21 1972-06-13 Pfizer Trialkoxy quinazolines
JPS4966691A (hu) * 1972-10-30 1974-06-27
US3935213A (en) 1973-12-05 1976-01-27 Pfizer Inc. Process for hypotensive 4-amino-2-(piperazin-1-yl) quinazoline derivatives
JPS50126682A (hu) * 1974-03-25 1975-10-04

Also Published As

Publication number Publication date
JPS5543465B2 (hu) 1980-11-06
PT66617B (en) 1978-10-27
SU946402A3 (ru) 1982-07-23
CH638203A5 (en) 1983-09-15
CS202069B2 (en) 1980-12-31
PL105558B1 (pl) 1979-10-31
NZ184168A (en) 1979-08-31
FR2355015A1 (fr) 1978-01-13
YU40164B (en) 1985-08-31
PL198874A1 (pl) 1978-04-10
LU77530A1 (fr) 1979-03-26
EG12922A (en) 1980-03-31
RO77308A (ro) 1981-08-17
DD131021A5 (de) 1978-05-24
PL111221B1 (en) 1980-08-30
AT356115B (de) 1980-04-10
BE855656A (fr) 1977-12-14
NO147838B (no) 1983-03-14
CH638517A5 (en) 1983-09-30
SE435380B (sv) 1984-09-24
FR2355015B1 (hu) 1981-07-24
DK240877A (da) 1977-12-16
GB1548856A (en) 1979-07-18
NO771919L (no) 1977-12-16
CH638516A5 (en) 1983-09-30
HK31481A (en) 1981-07-10
MY8100270A (en) 1981-12-31
IE45423B1 (en) 1982-08-25
IL52167A (en) 1981-01-30
ATA386977A (de) 1979-09-15
DE2725019A1 (de) 1977-12-22
PH22196A (en) 1988-06-28
FI771741A (hu) 1977-12-16
SE8107554L (sv) 1981-12-16
ZA773014B (en) 1978-04-26
AR218251A1 (es) 1980-05-30
PL113012B1 (en) 1980-11-29
SE7705745L (sv) 1977-12-16
YU132677A (en) 1982-08-31
NL7705939A (nl) 1977-12-19
BG35594A3 (en) 1984-05-15
IE45423L (en) 1977-12-15
NO147838C (no) 1983-06-22
RO73050A (ro) 1981-08-30
NL172543C (nl) 1983-09-16
FI66853C (fi) 1984-12-10
SU1033002A3 (ru) 1983-07-30
GR72288B (hu) 1983-10-17
NL172543B (nl) 1983-04-18
ES459364A1 (es) 1978-03-16
AU2558377A (en) 1978-09-07
JPS52153985A (en) 1977-12-21
CA1068698A (en) 1979-12-25
DK146625B (da) 1983-11-21
PT66617A (en) 1977-06-01
RO77330A (ro) 1981-06-22
DK146625C (da) 1984-06-04
BG35747A3 (en) 1984-06-15
FI66853B (fi) 1984-08-31
IL52167A0 (en) 1977-07-31
BG35748A3 (en) 1984-06-15
SE450120B (sv) 1987-06-09

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee