IL52167A - Preparation of 2-(4-substituted piperazinyl)-4-amino-quinazoline derivatives and corresponding 2-halo intermediates therefor - Google Patents

Preparation of 2-(4-substituted piperazinyl)-4-amino-quinazoline derivatives and corresponding 2-halo intermediates therefor

Info

Publication number
IL52167A
IL52167A IL52167A IL5216777A IL52167A IL 52167 A IL52167 A IL 52167A IL 52167 A IL52167 A IL 52167A IL 5216777 A IL5216777 A IL 5216777A IL 52167 A IL52167 A IL 52167A
Authority
IL
Israel
Prior art keywords
amino
preparation
quinazoline derivatives
substituted piperazinyl
intermediates therefor
Prior art date
Application number
IL52167A
Other versions
IL52167A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL52167A0 publication Critical patent/IL52167A0/en
Publication of IL52167A publication Critical patent/IL52167A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IL52167A 1976-06-15 1977-05-25 Preparation of 2-(4-substituted piperazinyl)-4-amino-quinazoline derivatives and corresponding 2-halo intermediates therefor IL52167A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69620176A 1976-06-15 1976-06-15

Publications (2)

Publication Number Publication Date
IL52167A0 IL52167A0 (en) 1977-07-31
IL52167A true IL52167A (en) 1981-01-30

Family

ID=24796111

Family Applications (1)

Application Number Title Priority Date Filing Date
IL52167A IL52167A (en) 1976-06-15 1977-05-25 Preparation of 2-(4-substituted piperazinyl)-4-amino-quinazoline derivatives and corresponding 2-halo intermediates therefor

Country Status (34)

Country Link
JP (1) JPS52153985A (en)
AR (1) AR218251A1 (en)
AT (1) AT356115B (en)
BE (1) BE855656A (en)
BG (3) BG35748A3 (en)
CA (1) CA1068698A (en)
CH (3) CH638203A5 (en)
CS (1) CS202069B2 (en)
DD (1) DD131021A5 (en)
DE (1) DE2725019A1 (en)
DK (1) DK146625C (en)
EG (1) EG12922A (en)
ES (1) ES459364A1 (en)
FI (1) FI66853C (en)
FR (1) FR2355015A1 (en)
GB (1) GB1548856A (en)
GR (1) GR72288B (en)
HK (1) HK31481A (en)
HU (1) HU177883B (en)
IE (1) IE45423B1 (en)
IL (1) IL52167A (en)
LU (1) LU77530A1 (en)
MY (1) MY8100270A (en)
NL (1) NL172543C (en)
NO (1) NO147838C (en)
NZ (1) NZ184168A (en)
PH (1) PH22196A (en)
PL (3) PL111221B1 (en)
PT (1) PT66617B (en)
RO (3) RO77330A (en)
SE (2) SE435380B (en)
SU (2) SU1033002A3 (en)
YU (1) YU40164B (en)
ZA (1) ZA773014B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3346675A1 (en) * 1983-12-23 1985-07-04 Beiersdorf Ag, 2000 Hamburg SUBSTITUTED 1- (4-AMINO-6,7-DIALKOXY-CHINAZOLINYL) -4- CYCLOHEXENYL DERIVATIVES OF PIPERAZINE AND HOMOPIPERAZINE, METHODS FOR THE PRODUCTION THEREOF, AND THEIR USE, AND ITS RELATED PRODUCTS
AT384218B (en) * 1985-12-04 1987-10-12 Gerot Pharmazeutika METHOD FOR PRODUCING NEW CHINAZOLINE DERIVATIVES
CA2077252C (en) * 1992-08-31 2001-04-10 Khashayar Karimian Methods of making ureas and guanidines, and intermediates therefor
IL112249A (en) 1994-01-25 2001-11-25 Warner Lambert Co Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds
US5654307A (en) * 1994-01-25 1997-08-05 Warner-Lambert Company Bicyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
IL112248A0 (en) 1994-01-25 1995-03-30 Warner Lambert Co Tricyclic heteroaromatic compounds and pharmaceutical compositions containing them
US5932538A (en) * 1996-02-02 1999-08-03 Nitromed, Inc. Nitrosated and nitrosylated α-adrenergic receptor antagonist compounds, compositions and their uses

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3511836A (en) 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
US3669968A (en) 1970-05-21 1972-06-13 Pfizer Trialkoxy quinazolines
JPS536156B2 (en) * 1972-10-30 1978-03-04
US3935213A (en) 1973-12-05 1976-01-27 Pfizer Inc. Process for hypotensive 4-amino-2-(piperazin-1-yl) quinazoline derivatives
JPS50126682A (en) * 1974-03-25 1975-10-04

Also Published As

Publication number Publication date
NL172543B (en) 1983-04-18
FR2355015A1 (en) 1978-01-13
SE8107554L (en) 1981-12-16
SE450120B (en) 1987-06-09
FI66853C (en) 1984-12-10
EG12922A (en) 1980-03-31
RO73050A (en) 1981-08-30
NL7705939A (en) 1977-12-19
IE45423L (en) 1977-12-15
PH22196A (en) 1988-06-28
PL105558B1 (en) 1979-10-31
GR72288B (en) 1983-10-17
SU1033002A3 (en) 1983-07-30
CH638516A5 (en) 1983-09-30
LU77530A1 (en) 1979-03-26
BE855656A (en) 1977-12-14
BG35748A3 (en) 1984-06-15
HU177883B (en) 1982-01-28
NO147838C (en) 1983-06-22
RO77330A (en) 1981-06-22
ZA773014B (en) 1978-04-26
YU40164B (en) 1985-08-31
RO77308A (en) 1981-08-17
CH638203A5 (en) 1983-09-15
SE435380B (en) 1984-09-24
AR218251A1 (en) 1980-05-30
DD131021A5 (en) 1978-05-24
NZ184168A (en) 1979-08-31
PL198874A1 (en) 1978-04-10
YU132677A (en) 1982-08-31
PT66617A (en) 1977-06-01
DK240877A (en) 1977-12-16
NL172543C (en) 1983-09-16
PL111221B1 (en) 1980-08-30
ATA386977A (en) 1979-09-15
CS202069B2 (en) 1980-12-31
IL52167A0 (en) 1977-07-31
JPS52153985A (en) 1977-12-21
FR2355015B1 (en) 1981-07-24
CH638517A5 (en) 1983-09-30
JPS5543465B2 (en) 1980-11-06
DK146625C (en) 1984-06-04
AT356115B (en) 1980-04-10
BG35747A3 (en) 1984-06-15
SE7705745L (en) 1977-12-16
PL113012B1 (en) 1980-11-29
PT66617B (en) 1978-10-27
FI771741A7 (en) 1977-12-16
SU946402A3 (en) 1982-07-23
MY8100270A (en) 1981-12-31
NO147838B (en) 1983-03-14
CA1068698A (en) 1979-12-25
IE45423B1 (en) 1982-08-25
DK146625B (en) 1983-11-21
DE2725019A1 (en) 1977-12-22
ES459364A1 (en) 1978-03-16
AU2558377A (en) 1978-09-07
FI66853B (en) 1984-08-31
GB1548856A (en) 1979-07-18
NO771919L (en) 1977-12-16
HK31481A (en) 1981-07-10
BG35594A3 (en) 1984-05-15

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