NO147838C - INTERMEDIATE FOR USE IN PREPARATION OF THE HYPOTENSIVE AGENT 2- (4- (2-FUROYL) PIPERAZIN-1-YL) -4-AMINO-6,7-DIMETOXYKINAZOLINE - Google Patents

INTERMEDIATE FOR USE IN PREPARATION OF THE HYPOTENSIVE AGENT 2- (4- (2-FUROYL) PIPERAZIN-1-YL) -4-AMINO-6,7-DIMETOXYKINAZOLINE

Info

Publication number
NO147838C
NO147838C NO771919A NO771919A NO147838C NO 147838 C NO147838 C NO 147838C NO 771919 A NO771919 A NO 771919A NO 771919 A NO771919 A NO 771919A NO 147838 C NO147838 C NO 147838C
Authority
NO
Norway
Prior art keywords
dimetoxykinazoline
furoyl
piperazin
amino
preparation
Prior art date
Application number
NO771919A
Other languages
Norwegian (no)
Other versions
NO147838B (en
NO771919L (en
Inventor
Philip Dietrich Hammen
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO771919L publication Critical patent/NO771919L/en
Publication of NO147838B publication Critical patent/NO147838B/en
Publication of NO147838C publication Critical patent/NO147838C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NO771919A 1976-06-15 1977-06-01 INTERMEDIATE FOR USE IN PREPARATION OF THE HYPOTENSIVE AGENT 2- (4- (2-FUROYL) PIPERAZIN-1-YL) -4-AMINO-6,7-DIMETOXYKINAZOLINE NO147838C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69620176A 1976-06-15 1976-06-15

Publications (3)

Publication Number Publication Date
NO771919L NO771919L (en) 1977-12-16
NO147838B NO147838B (en) 1983-03-14
NO147838C true NO147838C (en) 1983-06-22

Family

ID=24796111

Family Applications (1)

Application Number Title Priority Date Filing Date
NO771919A NO147838C (en) 1976-06-15 1977-06-01 INTERMEDIATE FOR USE IN PREPARATION OF THE HYPOTENSIVE AGENT 2- (4- (2-FUROYL) PIPERAZIN-1-YL) -4-AMINO-6,7-DIMETOXYKINAZOLINE

Country Status (34)

Country Link
JP (1) JPS52153985A (en)
AR (1) AR218251A1 (en)
AT (1) AT356115B (en)
BE (1) BE855656A (en)
BG (3) BG35748A3 (en)
CA (1) CA1068698A (en)
CH (3) CH638203A5 (en)
CS (1) CS202069B2 (en)
DD (1) DD131021A5 (en)
DE (1) DE2725019A1 (en)
DK (1) DK146625C (en)
EG (1) EG12922A (en)
ES (1) ES459364A1 (en)
FI (1) FI66853C (en)
FR (1) FR2355015A1 (en)
GB (1) GB1548856A (en)
GR (1) GR72288B (en)
HK (1) HK31481A (en)
HU (1) HU177883B (en)
IE (1) IE45423B1 (en)
IL (1) IL52167A (en)
LU (1) LU77530A1 (en)
MY (1) MY8100270A (en)
NL (1) NL172543C (en)
NO (1) NO147838C (en)
NZ (1) NZ184168A (en)
PH (1) PH22196A (en)
PL (3) PL105558B1 (en)
PT (1) PT66617B (en)
RO (3) RO77308A (en)
SE (2) SE435380B (en)
SU (2) SU1033002A3 (en)
YU (1) YU40164B (en)
ZA (1) ZA773014B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3346675A1 (en) * 1983-12-23 1985-07-04 Beiersdorf Ag, 2000 Hamburg SUBSTITUTED 1- (4-AMINO-6,7-DIALKOXY-CHINAZOLINYL) -4- CYCLOHEXENYL DERIVATIVES OF PIPERAZINE AND HOMOPIPERAZINE, METHODS FOR THE PRODUCTION THEREOF, AND THEIR USE, AND ITS RELATED PRODUCTS
AT384218B (en) * 1985-12-04 1987-10-12 Gerot Pharmazeutika METHOD FOR PRODUCING NEW CHINAZOLINE DERIVATIVES
CA2077252C (en) * 1992-08-31 2001-04-10 Khashayar Karimian Methods of making ureas and guanidines, and intermediates therefor
US5679683A (en) * 1994-01-25 1997-10-21 Warner-Lambert Company Tricyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
IL112249A (en) 1994-01-25 2001-11-25 Warner Lambert Co Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds
IL112248A0 (en) 1994-01-25 1995-03-30 Warner Lambert Co Tricyclic heteroaromatic compounds and pharmaceutical compositions containing them
US5932538A (en) * 1996-02-02 1999-08-03 Nitromed, Inc. Nitrosated and nitrosylated α-adrenergic receptor antagonist compounds, compositions and their uses

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3511836A (en) 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
US3669968A (en) 1970-05-21 1972-06-13 Pfizer Trialkoxy quinazolines
JPS536156B2 (en) * 1972-10-30 1978-03-04
US3935213A (en) 1973-12-05 1976-01-27 Pfizer Inc. Process for hypotensive 4-amino-2-(piperazin-1-yl) quinazoline derivatives
JPS50126682A (en) * 1974-03-25 1975-10-04

Also Published As

Publication number Publication date
FI66853B (en) 1984-08-31
SU946402A3 (en) 1982-07-23
RO77330A (en) 1981-06-22
FI771741A (en) 1977-12-16
EG12922A (en) 1980-03-31
FI66853C (en) 1984-12-10
ATA386977A (en) 1979-09-15
NL172543C (en) 1983-09-16
IE45423B1 (en) 1982-08-25
FR2355015A1 (en) 1978-01-13
NL172543B (en) 1983-04-18
GR72288B (en) 1983-10-17
CS202069B2 (en) 1980-12-31
DK240877A (en) 1977-12-16
PH22196A (en) 1988-06-28
LU77530A1 (en) 1979-03-26
IL52167A0 (en) 1977-07-31
SE435380B (en) 1984-09-24
PL198874A1 (en) 1978-04-10
RO73050A (en) 1981-08-30
DE2725019A1 (en) 1977-12-22
PL113012B1 (en) 1980-11-29
BG35748A3 (en) 1984-06-15
CA1068698A (en) 1979-12-25
CH638203A5 (en) 1983-09-15
SE8107554L (en) 1981-12-16
JPS52153985A (en) 1977-12-21
SE7705745L (en) 1977-12-16
NO147838B (en) 1983-03-14
PL111221B1 (en) 1980-08-30
BE855656A (en) 1977-12-14
DD131021A5 (en) 1978-05-24
GB1548856A (en) 1979-07-18
DK146625B (en) 1983-11-21
AU2558377A (en) 1978-09-07
IE45423L (en) 1977-12-15
HK31481A (en) 1981-07-10
SU1033002A3 (en) 1983-07-30
HU177883B (en) 1982-01-28
NZ184168A (en) 1979-08-31
NO771919L (en) 1977-12-16
SE450120B (en) 1987-06-09
CH638516A5 (en) 1983-09-30
RO77308A (en) 1981-08-17
JPS5543465B2 (en) 1980-11-06
YU40164B (en) 1985-08-31
IL52167A (en) 1981-01-30
ZA773014B (en) 1978-04-26
YU132677A (en) 1982-08-31
ES459364A1 (en) 1978-03-16
AT356115B (en) 1980-04-10
CH638517A5 (en) 1983-09-30
NL7705939A (en) 1977-12-19
PL105558B1 (en) 1979-10-31
BG35747A3 (en) 1984-06-15
PT66617B (en) 1978-10-27
PT66617A (en) 1977-06-01
AR218251A1 (en) 1980-05-30
DK146625C (en) 1984-06-04
MY8100270A (en) 1981-12-31
BG35594A3 (en) 1984-05-15
FR2355015B1 (en) 1981-07-24

Similar Documents

Publication Publication Date Title
AR214746A1 (en) PROCEDURE FOR THE PREPARATION OF 4- (3-AMINO-2-HYDROXY-PROPYLOXY) -BENZIMIDAZOL-2-ONAS AND 5- (3-AMINO-2-HYDROXY-PROPYLOXY) -1,2,3,4-TETRAHIDRO-2 , 3-DIOXO-QUINOXAZOLINES
NL7803312A (en) NEW 5- (4- (DIARYLMETHYL) -1-PIPERAZINYL ALKYL) - BENZIMIDAZOLE DERIVATIVES, AND THERAPEUTIC PREPARATIONS, CONTAINING SUCH DERIVATIVES.
NZ183450A (en) Preparation of the crystalline -form of 2-(4-(2-foroyl)-piperazin-1-yl)-4-amino-6,7-dimethoxy-quinazdine hydrochloride
NO800338L (en) PROCEDURE FOR THE PREPARATION OF NEW 4- (NAFTHYLMETHYL) PIPERIDE INGREDIATES.
NO770457L (en) PROCEDURES FOR THE PREPARATION OF CONDENSED PYRIMIDINE DERIVATIVES.
NO147838C (en) INTERMEDIATE FOR USE IN PREPARATION OF THE HYPOTENSIVE AGENT 2- (4- (2-FUROYL) PIPERAZIN-1-YL) -4-AMINO-6,7-DIMETOXYKINAZOLINE
NO142625C (en) ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE NEW PIPERAZINE DERIVATIVES
DK152120C (en) ANALOGY PROCEDURE FOR THE PREPARATION OF 4- (2-ACYLOXY-3-TERT.BUTYLAMINOPROPOXY) -INDEAL DERIVATIVES
AR213659A1 (en) PROCEDURE FOR THE PREPARATION OF 2- (4- (AROIL OR HETEROAROIL) -PIPERAZIN-1-IL) -4-AMINO-6,7-DIMETOXYQUINAZOLINES
NO154396C (en) ANALOGY PROCEDURE FOR THE PREPARATION OF NEW THERAPEUTICALLY ACTIVE HALOVINCAMON DERIVATIVES.
DK57778A (en) PROCEDURE FOR THE PREPARATION OF 1,3-DISUBSTITUTED URINE OR 2-THIORUINE
NO147306C (en) ANALOGY PROCEDURE FOR THE PREPARATION OF NEW PHARMACOLOGICALLY ACTIVE PIPERAZINE DERIVATIVES
DK158352C (en) PROCEDURE FOR PREPARING 6,7-DIMETHOXY-4-AMINO-2- (4- (2-FUROYL) -1-PIPERAZINYL) CHINAZOLINE HYDROCHLORIDE
NO802346L (en) PROCEDURE FOR THE PREPARATION OF 4- (Naphthalene oxide) -piperidine derivatives.
NO145239C (en) ANALOGY PROCEDURE FOR THE PREPARATION OF ANALGETIC ACTIVE 2,9-DIOXATRICYCLO (4.3.1.0 3.7) -DECANES
NO774262L (en) PROCEDURE FOR THE PREPARATION OF 6,7-DIMETHOXY-4-AMINO-2- (4- (2-FUROYL) -1-PIPERAZINYL) CHINAZOLINE WITH BLOOD PRESSURE-LOWING EFFECT
DK146510C (en) 2- (4- (2-FUROYL) PIPERAZIN-1-YL) -4-PHTHALIMIDO-6,7-DIMETHOXYQUINAZOLINE USED AS INTERMEDIATE IN THE PREPARATION OF 2- (4- (2-FUROYL) PIPERAZIN-1-YL) - 4-amino-6,7-dimethoxyquinazoline
IL52394A0 (en) The preparation of 2-(4-(2-furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline
NO774263L (en) INTERMEDIATE FOR THE PREPARATION OF 6,7-DIMETHOXY-4-AMINO-2- (4- (2-FUROYL) -1-PIPERAZINYL) KINAZOLINE WITH BLOOD PRESSURE-LOWING EFFECT
DK146763C (en) ANALOGY PROCEDURE FOR THE PREPARATION OF 1-SUBSTITUTED 4- (1,2-DIPHENYLETHYL) PIPERAZINE DERIVATIVES
NO773506L (en) PROCEDURES FOR THE PREPARATION OF N-6-CHLORNICOTINOYL-D, 1-HOMOCYSTEIN THIOLACTON
NO151826C (en) ANALOGY PROCEDURE FOR THE PREPARATION OF NEW, THERAPEUTICALLY ACTIVE 7-CHLORINE OR BROME-3,20-DIOXO-1,4-PREGNANCY AND-4 PREGNANCY
DK160987C (en) 9,10-DIHYDROXY-PERHYDROISOQUINOLINE DERIVATIVES USED AS INTERMEDIATE IN THE PREPARATION OF 14-HYDROXY-MORPHINANDER DERIVATIVES
AU492183B2 (en) Catalytic dehalogenation process for preparing 2-[4-(2-furoyl) piperazin-1-yl] -4-amino-6,7-dimethoxyquinazoline
IT7823513A0 (en) COPOLYESTERS, PROCEDURE FOR THEIR PREPARATION AND THEIR USE.