DK146625C - 2-halogen-4-(beskyttet-amino)quinazolinderivater til anvendelse som mellemprodukter ved fremstilling af 2-(4-(2-furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazolin - Google Patents

2-halogen-4-(beskyttet-amino)quinazolinderivater til anvendelse som mellemprodukter ved fremstilling af 2-(4-(2-furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazolin

Info

Publication number
DK146625C
DK146625C DK240877A DK240877A DK146625C DK 146625 C DK146625 C DK 146625C DK 240877 A DK240877 A DK 240877A DK 240877 A DK240877 A DK 240877A DK 146625 C DK146625 C DK 146625C
Authority
DK
Denmark
Prior art keywords
amino
dimethoxyquinazine
furoyl
piperazin
intermediates
Prior art date
Application number
DK240877A
Other languages
English (en)
Other versions
DK240877A (da
DK146625B (da
Inventor
Philip Dietrich Hammen
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK240877A publication Critical patent/DK240877A/da
Priority to DK441580A priority Critical patent/DK146510C/da
Publication of DK146625B publication Critical patent/DK146625B/da
Application granted granted Critical
Publication of DK146625C publication Critical patent/DK146625C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK240877A 1976-06-15 1977-06-01 2-halogen-4-(beskyttet-amino)quinazolinderivater til anvendelse som mellemprodukter ved fremstilling af 2-(4-(2-furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazolin DK146625C (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK441580A DK146510C (da) 1976-06-15 1980-10-17 2-(4-(2-furoyl)piperazin-1-yl)-4-phthalimido-6,7-dimethoxyquinazolin til anvendelse som mellemprodukt ved fremstilling af 2-(4-(2-furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazolin

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69620176A 1976-06-15 1976-06-15
US69620176 1976-06-15

Publications (3)

Publication Number Publication Date
DK240877A DK240877A (da) 1977-12-16
DK146625B DK146625B (da) 1983-11-21
DK146625C true DK146625C (da) 1984-06-04

Family

ID=24796111

Family Applications (1)

Application Number Title Priority Date Filing Date
DK240877A DK146625C (da) 1976-06-15 1977-06-01 2-halogen-4-(beskyttet-amino)quinazolinderivater til anvendelse som mellemprodukter ved fremstilling af 2-(4-(2-furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazolin

Country Status (34)

Country Link
JP (1) JPS52153985A (da)
AR (1) AR218251A1 (da)
AT (1) AT356115B (da)
BE (1) BE855656A (da)
BG (3) BG35748A3 (da)
CA (1) CA1068698A (da)
CH (3) CH638203A5 (da)
CS (1) CS202069B2 (da)
DD (1) DD131021A5 (da)
DE (1) DE2725019A1 (da)
DK (1) DK146625C (da)
EG (1) EG12922A (da)
ES (1) ES459364A1 (da)
FI (1) FI66853C (da)
FR (1) FR2355015A1 (da)
GB (1) GB1548856A (da)
GR (1) GR72288B (da)
HK (1) HK31481A (da)
HU (1) HU177883B (da)
IE (1) IE45423B1 (da)
IL (1) IL52167A (da)
LU (1) LU77530A1 (da)
MY (1) MY8100270A (da)
NL (1) NL172543C (da)
NO (1) NO147838C (da)
NZ (1) NZ184168A (da)
PH (1) PH22196A (da)
PL (3) PL111221B1 (da)
PT (1) PT66617B (da)
RO (3) RO77330A (da)
SE (2) SE435380B (da)
SU (2) SU1033002A3 (da)
YU (1) YU40164B (da)
ZA (1) ZA773014B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3346675A1 (de) * 1983-12-23 1985-07-04 Beiersdorf Ag, 2000 Hamburg Substituierte 1-(4-amino-6,7-dialkoxy-chinazolinyl)-4- cyclohexenyl-derivate des piperazins und homopiperazins, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen und zwischenprodukte
AT384218B (de) * 1985-12-04 1987-10-12 Gerot Pharmazeutika Verfahren zur herstellung von neuen chinazolin-derivaten
CA2077252C (en) * 1992-08-31 2001-04-10 Khashayar Karimian Methods of making ureas and guanidines, and intermediates therefor
US5679683A (en) * 1994-01-25 1997-10-21 Warner-Lambert Company Tricyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
IL112249A (en) 1994-01-25 2001-11-25 Warner Lambert Co Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds
IL112248A0 (en) 1994-01-25 1995-03-30 Warner Lambert Co Tricyclic heteroaromatic compounds and pharmaceutical compositions containing them
US5932538A (en) * 1996-02-02 1999-08-03 Nitromed, Inc. Nitrosated and nitrosylated α-adrenergic receptor antagonist compounds, compositions and their uses

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3511836A (en) 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
US3669968A (en) 1970-05-21 1972-06-13 Pfizer Trialkoxy quinazolines
JPS4966691A (da) * 1972-10-30 1974-06-27
US3935213A (en) 1973-12-05 1976-01-27 Pfizer Inc. Process for hypotensive 4-amino-2-(piperazin-1-yl) quinazoline derivatives
JPS50126682A (da) * 1974-03-25 1975-10-04

Also Published As

Publication number Publication date
JPS5543465B2 (da) 1980-11-06
PT66617B (en) 1978-10-27
SU946402A3 (ru) 1982-07-23
CH638203A5 (en) 1983-09-15
CS202069B2 (en) 1980-12-31
PL105558B1 (pl) 1979-10-31
NZ184168A (en) 1979-08-31
FR2355015A1 (fr) 1978-01-13
YU40164B (en) 1985-08-31
PL198874A1 (pl) 1978-04-10
LU77530A1 (fr) 1979-03-26
EG12922A (en) 1980-03-31
RO77308A (ro) 1981-08-17
DD131021A5 (de) 1978-05-24
HU177883B (en) 1982-01-28
PL111221B1 (en) 1980-08-30
AT356115B (de) 1980-04-10
BE855656A (fr) 1977-12-14
NO147838B (no) 1983-03-14
CH638517A5 (en) 1983-09-30
SE435380B (sv) 1984-09-24
FR2355015B1 (da) 1981-07-24
DK240877A (da) 1977-12-16
GB1548856A (en) 1979-07-18
NO771919L (no) 1977-12-16
CH638516A5 (en) 1983-09-30
HK31481A (en) 1981-07-10
MY8100270A (en) 1981-12-31
IE45423B1 (en) 1982-08-25
IL52167A (en) 1981-01-30
ATA386977A (de) 1979-09-15
DE2725019A1 (de) 1977-12-22
PH22196A (en) 1988-06-28
FI771741A (da) 1977-12-16
SE8107554L (sv) 1981-12-16
ZA773014B (en) 1978-04-26
AR218251A1 (es) 1980-05-30
PL113012B1 (en) 1980-11-29
SE7705745L (sv) 1977-12-16
YU132677A (en) 1982-08-31
NL7705939A (nl) 1977-12-19
BG35594A3 (en) 1984-05-15
IE45423L (en) 1977-12-15
NO147838C (no) 1983-06-22
RO73050A (ro) 1981-08-30
NL172543C (nl) 1983-09-16
FI66853C (fi) 1984-12-10
SU1033002A3 (ru) 1983-07-30
GR72288B (da) 1983-10-17
NL172543B (nl) 1983-04-18
ES459364A1 (es) 1978-03-16
AU2558377A (en) 1978-09-07
JPS52153985A (en) 1977-12-21
CA1068698A (en) 1979-12-25
DK146625B (da) 1983-11-21
PT66617A (en) 1977-06-01
RO77330A (ro) 1981-06-22
BG35747A3 (en) 1984-06-15
FI66853B (fi) 1984-08-31
IL52167A0 (en) 1977-07-31
BG35748A3 (en) 1984-06-15
SE450120B (sv) 1987-06-09

Similar Documents

Publication Publication Date Title
DK95678A (da) Tetrahydrofuranetherderivater fremgangsmaade til fremtilling deraf samt deres anvendelse som herbicider
NZ183450A (en) Preparation of the crystalline -form of 2-(4-(2-foroyl)-piperazin-1-yl)-4-amino-6,7-dimethoxy-quinazdine hydrochloride
DK300578A (da) 2-(eller 4-) amino-alkylthiopyrimidiner som herbicider
DK146625C (da) 2-halogen-4-(beskyttet-amino)quinazolinderivater til anvendelse som mellemprodukter ved fremstilling af 2-(4-(2-furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazolin
DK140695B (da) Analogifremgangsmaade til fremstilling af 2,4-diamo-6,7-dimethoxyquinazolinderivater eller syreadditionssalte heraf
AR219173A1 (es) Procedimiento para la preparacion de 4-(2-hidroxi-3-(amino)propoxi)-2-bencimidazolinonas
AR213659A1 (es) Procedimiento para la preparacion de 2-(4-(aroil o heteroaroil)-piperazin-1-il)-4-amino-6,7-dimetoxiquinazolinas
DK158352C (da) Fremgangsmaade til fremstilling af 6,7-dimethoxy-4-amino-2-(4-(2-furoyl)-1-piperazinyl)kinazolinhydrochlorid
DK437287D0 (da) 2,3-dihydrofuranderivater, deres fremstilling og deres anvendelse som mellemprodukter til fremstilling af tetrahydrofuranderivater
DK146510C (da) 2-(4-(2-furoyl)piperazin-1-yl)-4-phthalimido-6,7-dimethoxyquinazolin til anvendelse som mellemprodukt ved fremstilling af 2-(4-(2-furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazolin
DK160548C (da) 4-hydroxymethyl-2-pyrrolidinoner til anvendelse som mellemprodukter ved fremstilling af 4-(4-disubstitueret piperidinylmethyl)-3,3-diphenyl-2-pyrrolidinoner
DK422879A (da) Fremgangsmaade til fremstilling af n-(1-methyl-2-pyrrolidinylmethyl)-2,3-dimethoxy-5-methylsulfamoyl-benzamid eller derivater deraf
DK122960B (da) Quinazolinderivater til anvendelse som mellemprodukter ved fremstillingen af 1,4-benzodiazepin-4-oxider.
DK45579A (da) Spiro-derivater af 3-(3,5-dihalogenphenyl)-oxazoldin-2,4-dioner fremgangsmaade til fremstilling deraf samt deres anvendelse som fungcider
DK558277A (da) Fremgangsmaade til fremstilling af 6,7-dimethoxy4-amino-2-(4-(2-furoyl)-1-piperazinyl) quinazolin med blodtrykssaenkende virkning
DK142575C (da) 4-hydroxyindazolderivater til anvendelse som mellemprodukter til fremstilling af indazolyl-(4)-oxy-propanolaminderivater med beta-receptorblokerende virkning
DK145822C (da) 3,4-dimethoxy-6-(4-(2-furoyl)-1-piperazinylthiocarbamido)benzonitril til anvendelse som mellemprodukt ved fremstillingen af 6,7-dimethoxy-4-amino-2-(4-(2-furoyl)-1-piperazinyl)quinazolin
NO148415C (no) Mellomprodukt for anvendelse ved fremstilling av n-(2-amino-3,5-dibrombenzyl)-n-metylcykloheksylamin
DK397480A (da) I furoylgruppen halogen-substituerede 2-(4-(2-furoyl) piperazin-1-yl)-4-amin-6,7-dimethoxyquinazoliner til brug som mellemprodukter ved fremstilling af 2-(4-(2-furoyl)-piperazin-1-yl)4-amino-6,7-dimethoxyquinazolin
IL52394A0 (en) The preparation of 2-(4-(2-furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline
DK92375A (da) Fremgangsmade til fremstilling af substituerede benzamider eller syreadditionssalte, kvaternere ammoniumsalte eller optisk aktive derivater deraf
DK145718C (da) Dibromforbindelse til anvendelse som mellemprodukt ved fremstilling af n-(2-amino-3,5-dibrombenzyl)-n-metylcyclohexylamin
DK597188A (da) 9,10-dihydroxy-perhydroisoquinolinderivater til anvendelse som mellemprodukt ved fremstilling af 14-hydroxymorphinanderivater
DK374484A (da) 1,4-dihydropyridinderivater til anvendelse som mellemprodukter ved fremstilling af farmaceutisk aktive 1,4-dihydropyridinderivater
DK146763C (da) Analogifremgangsmaade til fremstilling af 1-substituerede 4-(1,2-diphenylethyl)piperazinderivater

Legal Events

Date Code Title Description
PBP Patent lapsed