NZ184168A - Preparation of 4-amino-(6,7-di-or 6,7,8-tri)-methoxy-2-(4-substituted piperazin-1-yl)-quinazolines and certain 4-substitutedamino quinazoline precursors thereto - Google Patents

Preparation of 4-amino-(6,7-di-or 6,7,8-tri)-methoxy-2-(4-substituted piperazin-1-yl)-quinazolines and certain 4-substitutedamino quinazoline precursors thereto

Info

Publication number
NZ184168A
NZ184168A NZ184168A NZ18416877A NZ184168A NZ 184168 A NZ184168 A NZ 184168A NZ 184168 A NZ184168 A NZ 184168A NZ 18416877 A NZ18416877 A NZ 18416877A NZ 184168 A NZ184168 A NZ 184168A
Authority
NZ
New Zealand
Prior art keywords
substitutedamino
quinazolines
quinazoline
precursors
methoxy
Prior art date
Application number
NZ184168A
Other languages
English (en)
Inventor
Pd Hammen
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NZ184168A publication Critical patent/NZ184168A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NZ184168A 1976-06-15 1977-05-20 Preparation of 4-amino-(6,7-di-or 6,7,8-tri)-methoxy-2-(4-substituted piperazin-1-yl)-quinazolines and certain 4-substitutedamino quinazoline precursors thereto NZ184168A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69620176A 1976-06-15 1976-06-15

Publications (1)

Publication Number Publication Date
NZ184168A true NZ184168A (en) 1979-08-31

Family

ID=24796111

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ184168A NZ184168A (en) 1976-06-15 1977-05-20 Preparation of 4-amino-(6,7-di-or 6,7,8-tri)-methoxy-2-(4-substituted piperazin-1-yl)-quinazolines and certain 4-substitutedamino quinazoline precursors thereto

Country Status (34)

Country Link
JP (1) JPS52153985A (da)
AR (1) AR218251A1 (da)
AT (1) AT356115B (da)
BE (1) BE855656A (da)
BG (3) BG35748A3 (da)
CA (1) CA1068698A (da)
CH (3) CH638203A5 (da)
CS (1) CS202069B2 (da)
DD (1) DD131021A5 (da)
DE (1) DE2725019A1 (da)
DK (1) DK146625C (da)
EG (1) EG12922A (da)
ES (1) ES459364A1 (da)
FI (1) FI66853C (da)
FR (1) FR2355015A1 (da)
GB (1) GB1548856A (da)
GR (1) GR72288B (da)
HK (1) HK31481A (da)
HU (1) HU177883B (da)
IE (1) IE45423B1 (da)
IL (1) IL52167A (da)
LU (1) LU77530A1 (da)
MY (1) MY8100270A (da)
NL (1) NL172543C (da)
NO (1) NO147838C (da)
NZ (1) NZ184168A (da)
PH (1) PH22196A (da)
PL (3) PL111221B1 (da)
PT (1) PT66617B (da)
RO (3) RO77330A (da)
SE (2) SE435380B (da)
SU (2) SU1033002A3 (da)
YU (1) YU40164B (da)
ZA (1) ZA773014B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3346675A1 (de) * 1983-12-23 1985-07-04 Beiersdorf Ag, 2000 Hamburg Substituierte 1-(4-amino-6,7-dialkoxy-chinazolinyl)-4- cyclohexenyl-derivate des piperazins und homopiperazins, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen und zwischenprodukte
AT384218B (de) * 1985-12-04 1987-10-12 Gerot Pharmazeutika Verfahren zur herstellung von neuen chinazolin-derivaten
CA2077252C (en) * 1992-08-31 2001-04-10 Khashayar Karimian Methods of making ureas and guanidines, and intermediates therefor
US5679683A (en) * 1994-01-25 1997-10-21 Warner-Lambert Company Tricyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
IL112249A (en) 1994-01-25 2001-11-25 Warner Lambert Co Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds
IL112248A0 (en) 1994-01-25 1995-03-30 Warner Lambert Co Tricyclic heteroaromatic compounds and pharmaceutical compositions containing them
US5932538A (en) * 1996-02-02 1999-08-03 Nitromed, Inc. Nitrosated and nitrosylated α-adrenergic receptor antagonist compounds, compositions and their uses

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3511836A (en) 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
US3669968A (en) 1970-05-21 1972-06-13 Pfizer Trialkoxy quinazolines
JPS4966691A (da) * 1972-10-30 1974-06-27
US3935213A (en) 1973-12-05 1976-01-27 Pfizer Inc. Process for hypotensive 4-amino-2-(piperazin-1-yl) quinazoline derivatives
JPS50126682A (da) * 1974-03-25 1975-10-04

Also Published As

Publication number Publication date
JPS5543465B2 (da) 1980-11-06
PT66617B (en) 1978-10-27
SU946402A3 (ru) 1982-07-23
CH638203A5 (en) 1983-09-15
CS202069B2 (en) 1980-12-31
PL105558B1 (pl) 1979-10-31
FR2355015A1 (fr) 1978-01-13
YU40164B (en) 1985-08-31
PL198874A1 (pl) 1978-04-10
LU77530A1 (fr) 1979-03-26
EG12922A (en) 1980-03-31
RO77308A (ro) 1981-08-17
DD131021A5 (de) 1978-05-24
HU177883B (en) 1982-01-28
PL111221B1 (en) 1980-08-30
AT356115B (de) 1980-04-10
BE855656A (fr) 1977-12-14
NO147838B (no) 1983-03-14
CH638517A5 (en) 1983-09-30
SE435380B (sv) 1984-09-24
FR2355015B1 (da) 1981-07-24
DK240877A (da) 1977-12-16
GB1548856A (en) 1979-07-18
NO771919L (no) 1977-12-16
CH638516A5 (en) 1983-09-30
HK31481A (en) 1981-07-10
MY8100270A (en) 1981-12-31
IE45423B1 (en) 1982-08-25
IL52167A (en) 1981-01-30
ATA386977A (de) 1979-09-15
DE2725019A1 (de) 1977-12-22
PH22196A (en) 1988-06-28
FI771741A (da) 1977-12-16
SE8107554L (sv) 1981-12-16
ZA773014B (en) 1978-04-26
AR218251A1 (es) 1980-05-30
PL113012B1 (en) 1980-11-29
SE7705745L (sv) 1977-12-16
YU132677A (en) 1982-08-31
NL7705939A (nl) 1977-12-19
BG35594A3 (en) 1984-05-15
IE45423L (en) 1977-12-15
NO147838C (no) 1983-06-22
RO73050A (ro) 1981-08-30
NL172543C (nl) 1983-09-16
FI66853C (fi) 1984-12-10
SU1033002A3 (ru) 1983-07-30
GR72288B (da) 1983-10-17
NL172543B (nl) 1983-04-18
ES459364A1 (es) 1978-03-16
AU2558377A (en) 1978-09-07
JPS52153985A (en) 1977-12-21
CA1068698A (en) 1979-12-25
DK146625B (da) 1983-11-21
PT66617A (en) 1977-06-01
RO77330A (ro) 1981-06-22
DK146625C (da) 1984-06-04
BG35747A3 (en) 1984-06-15
FI66853B (fi) 1984-08-31
IL52167A0 (en) 1977-07-31
BG35748A3 (en) 1984-06-15
SE450120B (sv) 1987-06-09

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