FI3889145T3 - 8-syaani-5-piperidinokinoliineja TLR7/8-antagonisteina ja niiden käyttö immunologisten häiriöiden hoitoon - Google Patents

8-syaani-5-piperidinokinoliineja TLR7/8-antagonisteina ja niiden käyttö immunologisten häiriöiden hoitoon Download PDF

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Publication number
FI3889145T3
FI3889145T3 FIEP21172996.7T FI21172996T FI3889145T3 FI 3889145 T3 FI3889145 T3 FI 3889145T3 FI 21172996 T FI21172996 T FI 21172996T FI 3889145 T3 FI3889145 T3 FI 3889145T3
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disease
acceptable salt
compound
pharmaceutically acceptable
compound according
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FIEP21172996.7T
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English (en)
Finnish (fi)
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Brian Sherer
Nadia Brugger
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Merck Patent Gmbh
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
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FIEP21172996.7T 2015-12-17 2016-12-16 8-syaani-5-piperidinokinoliineja TLR7/8-antagonisteina ja niiden käyttö immunologisten häiriöiden hoitoon FI3889145T3 (fi)

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US201562268765P 2015-12-17 2015-12-17
US201662353603P 2016-06-23 2016-06-23

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MY196319A (en) 2015-12-17 2023-03-24 Merck Patent Gmbh Polycyclic TLR7/8 Antagonists and use Thereof in the Treatment of Immune Disorders
TWI794171B (zh) 2016-05-11 2023-03-01 美商滬亞生物國際有限公司 Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療
TWI808055B (zh) 2016-05-11 2023-07-11 美商滬亞生物國際有限公司 Hdac 抑制劑與 pd-1 抑制劑之組合治療
EP3484865B1 (en) 2016-07-14 2022-09-14 Crinetics Pharmaceuticals, Inc. Somatostatin modulators and uses thereof
CN109563075B (zh) 2016-08-08 2022-09-30 默克专利股份公司 Tlr7/8拮抗剂及其用途
FI3526323T3 (fi) 2016-10-14 2023-06-06 Prec Biosciences Inc Hepatiitti B -viruksen genomissa oleville tunnistussekvensseille spesifisiä muokattuja meganukleaaseja
WO2018089695A1 (en) * 2016-11-11 2018-05-17 Dynavax Technologies Corporation Toll-like receptor antagonist compounds and methods of use
CN118894840A (zh) * 2017-07-18 2024-11-05 默克专利股份公司 Tlr7/8拮抗剂及其用途
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