DK3889145T3 - 8-cyano-5-piperidino-quinoliner som TLR7/8-antagonister og anvendelser deraf til behandling af immunsygdomme - Google Patents

8-cyano-5-piperidino-quinoliner som TLR7/8-antagonister og anvendelser deraf til behandling af immunsygdomme Download PDF

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Publication number
DK3889145T3
DK3889145T3 DK21172996.7T DK21172996T DK3889145T3 DK 3889145 T3 DK3889145 T3 DK 3889145T3 DK 21172996 T DK21172996 T DK 21172996T DK 3889145 T3 DK3889145 T3 DK 3889145T3
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tlr7
quinolines
piperidino
antagonists
cyano
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DK21172996.7T
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Danish (da)
English (en)
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Brian Sherer
Nadia Brugger
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Merck Patent Gmbh
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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DK21172996.7T 2015-12-17 2016-12-16 8-cyano-5-piperidino-quinoliner som TLR7/8-antagonister og anvendelser deraf til behandling af immunsygdomme DK3889145T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562268765P 2015-12-17 2015-12-17
US201662353603P 2016-06-23 2016-06-23
EP16840344.2A EP3390389B1 (en) 2015-12-17 2016-12-16 Polycyclic tlr7/8 antagonists and use thereof in the treatment of immune disorders

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DK3889145T3 true DK3889145T3 (da) 2024-03-18

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TWI808055B (zh) 2016-05-11 2023-07-11 美商滬亞生物國際有限公司 Hdac 抑制劑與 pd-1 抑制劑之組合治療
TWI794171B (zh) 2016-05-11 2023-03-01 美商滬亞生物國際有限公司 Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療
AU2017296392B2 (en) 2016-07-14 2020-09-24 Crinetics Pharmaceuticals, Inc. Somatostatin modulators and uses thereof
AU2017311047B2 (en) * 2016-08-08 2021-07-22 Merck Patent Gmbh TLR7/8 antagonists and uses thereof
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