JP2013520405A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2013520405A5 JP2013520405A5 JP2012553344A JP2012553344A JP2013520405A5 JP 2013520405 A5 JP2013520405 A5 JP 2013520405A5 JP 2012553344 A JP2012553344 A JP 2012553344A JP 2012553344 A JP2012553344 A JP 2012553344A JP 2013520405 A5 JP2013520405 A5 JP 2013520405A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- pharmaceutically acceptable
- corneal
- composition according
- tgf
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/709,895 US8158589B2 (en) | 2003-08-22 | 2010-02-22 | Peptides with the capacity to bind to transforming growth factor β1 (TGF-β1) |
| US12/709,895 | 2010-02-22 | ||
| PCT/EP2011/052543 WO2011101478A1 (en) | 2010-02-22 | 2011-02-21 | USE OF TRANSFORMING GROWTH FACTOR - BETA 1 (TGF-β1) INHIBITOR PEPTIDES FOR THE TREATMENT OF CORNEAL FIBROSIS AND/OR HAZE |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013520405A JP2013520405A (ja) | 2013-06-06 |
| JP2013520405A5 true JP2013520405A5 (enExample) | 2014-04-10 |
Family
ID=43757920
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012553344A Withdrawn JP2013520405A (ja) | 2010-02-22 | 2011-02-21 | 角膜の繊維症および／または濁りを治療するための、形質転換成長因子−β１（ＴＧＦ−β１）インヒビターペプチドの使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US8158589B2 (enExample) |
| EP (1) | EP2538962A1 (enExample) |
| JP (1) | JP2013520405A (enExample) |
| CN (1) | CN102791283A (enExample) |
| AU (1) | AU2011217181A1 (enExample) |
| BR (1) | BR112012020953A2 (enExample) |
| CA (1) | CA2790625A1 (enExample) |
| MX (1) | MX2012009748A (enExample) |
| RU (1) | RU2012140704A (enExample) |
| WO (1) | WO2011101478A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130158103A1 (en) * | 2011-11-23 | 2013-06-20 | The Curators Of The University Of Missouri | Method of Tissue-Selective Targeted Gene Transfer |
| ES2423382B1 (es) * | 2012-02-16 | 2014-07-15 | Consejo Superior De Investigaciones Científicas (Csic) | Inhibidor de la produccion de endoglina soluble y su aplicacion en patologias donde la endoglina soluble tiene un efecto patogenico |
| WO2013148155A1 (en) * | 2012-03-26 | 2013-10-03 | Digna Biotech Usa, Llc | Compositions and methods for the treatment of dry eye disease |
| WO2014028862A1 (en) | 2012-08-17 | 2014-02-20 | Cornell University | Use of dna in circulating exosomes as a diagnostic marker for metastasic disease |
| BR112016002015A2 (pt) * | 2013-07-30 | 2017-08-01 | Kyoto Prefectural Public Univ Corp | medicamentos terapêuticos para ecm em endotélio da córnea |
| CA2927898C (en) | 2013-10-31 | 2021-11-16 | Kyoto Prefectural Public University Corporation | Therapeutic drug for diseases related to endoplasmic reticulum cell death in corneal endothelium |
| US10813920B2 (en) | 2013-11-14 | 2020-10-27 | The Doshisha | Drug for treating corneal endothelium by promoting cell proliferation or inhibiting cell damage |
| EP3125907A4 (en) | 2014-04-01 | 2017-11-29 | Cornell University | Use of double-stranded dna in exosomes: a novel biomarker in cancer detection |
| WO2016057702A2 (en) | 2014-10-07 | 2016-04-14 | Cornell University | Methods for prognosing and preventing metastatic liver disease |
| US11971402B2 (en) | 2015-04-24 | 2024-04-30 | Cornell University | Methods and reagents for determination and treatment of organotropic metastasis |
| CN108368043B (zh) * | 2015-10-27 | 2022-11-29 | 台北医学大学 | 用于治疗及/或预防纤维化疾病的吲哚啉衍生物 |
| CA3008113A1 (en) | 2015-12-24 | 2017-06-29 | The Doshisha | Drug for treating or preventing disorder caused by tgf-.beta. signals, and application thereof |
| CN117535350A (zh) * | 2016-05-20 | 2024-02-09 | 哈佛学院董事及会员团体 | 年龄相关疾病和病症的基因治疗方法 |
| CA3070938A1 (en) | 2017-07-26 | 2019-01-31 | The Doshisha | Drug for treating or preventing disorder caused by tgf-.beta. signalling, and application thereof |
| WO2019234221A1 (en) | 2018-06-08 | 2019-12-12 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for stratification and treatment of a patient suffering from chronic lymphocytic leukemia |
| GB201908012D0 (en) * | 2019-06-05 | 2019-07-17 | Io Biotech Aps | TGF-Beta vaccine |
| RU2700941C1 (ru) * | 2019-07-05 | 2019-09-24 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр реабилитации и курортологии" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ РК" Минздрава России) | Способ предупреждения развития помутнения роговицы при ее механических травмах |
| RU2701178C1 (ru) * | 2019-07-10 | 2019-09-25 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр реабилитации и курортологии" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ РК" Минздрава России) | Способ ускорения заживления роговицы при ее механических травмах |
| CN110483648A (zh) * | 2019-08-27 | 2019-11-22 | 南京安吉生物科技有限公司 | 一种融合多肽及其应用 |
| CN110862434B (zh) * | 2019-10-28 | 2021-07-06 | 中山大学 | 一种可促进TGF-β1蛋白靶向降解的化合物及其制备方法与应用 |
| JP2020073483A (ja) * | 2019-10-30 | 2020-05-14 | 京都府公立大学法人 | 角膜内皮ｅｃｍ治療薬 |
| EP4269429A4 (en) * | 2020-12-23 | 2025-07-30 | Korea Inst Sci & Tech | NEW PEPTIDE CAPABLE OF INHIBITING TGF-BETA SIGNALING AND ITS UTILIZATION |
| CN115040535B (zh) * | 2022-08-15 | 2022-12-16 | 华南理工大学 | 硫酸化透明质酸在制备预防角膜纤维化、角膜瘢痕滴眼液中的应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4550022A (en) | 1981-10-05 | 1985-10-29 | Alcon Laboratories, Inc. | Tissue irrigating solution |
| JPH08151396A (ja) | 1994-11-28 | 1996-06-11 | Teijin Ltd | Ｈｌａ結合性オリゴペプチド及びそれを含有する免疫調節剤 |
| WO1998024466A1 (en) * | 1996-12-05 | 1998-06-11 | Alcon Laboratories, Inc. | THE USE OF INHIBITORS OF TGF-β'S FUNCTIONS TO AMELIORATE OCULAR PATHOLOGY |
| US6660843B1 (en) | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
| ES2146552B1 (es) * | 1998-11-24 | 2001-04-16 | Inst Cientifico Tecnol Navarra | Peptidos inhibidores de tgf/31 |
| US6399107B1 (en) | 1998-12-22 | 2002-06-04 | Alcon Laboratories, Inc. | Use of inhibitors of gag synthesis for the treatment of corneal haze |
| AU2002215334B2 (en) | 2000-10-13 | 2005-11-10 | The Johns Hopkins University | Plasminogen activator to prevent corneal and subepithelial haze after laser vision correction surgery |
| ES2304069B1 (es) | 2003-08-22 | 2009-08-12 | Proyecto De Biomedicina Cima, S.L. | Peptidos con capacidad de unirse al factor transformante de crecimiento beta 1 (tgf-b1). |
| WO2007048857A1 (es) | 2005-10-24 | 2007-05-03 | Proyecto De Biomedicina Cima, S.L. | USO DE PÉPTIDOS INHIBIDORES DE TGF- βl EN LA PREPARACIÓN DE UN AGENTE MODULADOR DE LA RESPUESTA INMUNE |
| US7582609B2 (en) * | 2006-03-01 | 2009-09-01 | Digna Biotech, S.L. | Method for the treatment of skin fibrosis and suitable compositions for such treatment |
-
2010
- 2010-02-22 US US12/709,895 patent/US8158589B2/en not_active Expired - Fee Related
-
2011
- 2011-02-21 MX MX2012009748A patent/MX2012009748A/es not_active Application Discontinuation
- 2011-02-21 WO PCT/EP2011/052543 patent/WO2011101478A1/en not_active Ceased
- 2011-02-21 JP JP2012553344A patent/JP2013520405A/ja not_active Withdrawn
- 2011-02-21 CA CA2790625A patent/CA2790625A1/en not_active Abandoned
- 2011-02-21 EP EP11704455A patent/EP2538962A1/en not_active Withdrawn
- 2011-02-21 US US13/580,103 patent/US20120315256A1/en not_active Abandoned
- 2011-02-21 AU AU2011217181A patent/AU2011217181A1/en not_active Abandoned
- 2011-02-21 BR BR112012020953A patent/BR112012020953A2/pt not_active IP Right Cessation
- 2011-02-21 RU RU2012140704/15A patent/RU2012140704A/ru not_active Application Discontinuation
- 2011-02-21 CN CN2011800104876A patent/CN102791283A/zh active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2013520405A5 (enExample) | ||
| JP2015517488A5 (enExample) | ||
| AU2018201997B2 (en) | Peptides which inhibit activated receptors and their use in cosmetic or pharmaceutical compositions | |
| RU2012140704A (ru) | Способ профилактики и/или лечения фиброза и/или помутнения роговицы (варианты), способ получения фармацевтической композиции для профилактики и/или лечения фиброза и/или помутнения роговицы и глазная фармацевтическая композиция | |
| MX2017004592A (es) | Formulaciones farmaceuticas para la administracion oral de farmacos peptidicos o proteinicos. | |
| EA201270221A1 (ru) | Лечение болезни крона с применением лаквинимода | |
| JP2013542247A5 (enExample) | ||
| WO2013101897A3 (en) | Improved compositions and methods for delivery of omeprazole plus acetylsalicylic acid | |
| EA201592250A1 (ru) | Пиразолопирролидиновые производные и их применение в лечение заболеваний | |
| JP2015518818A5 (enExample) | ||
| NZ600544A (en) | Compositions and methods for the treatment of angiogenesis-related eye diseases | |
| WO2014205229A8 (en) | Use of high dose pridopidine for treating huntington's disease | |
| EA201592256A1 (ru) | Производные имидазопирролидинона и их применение при лечении заболеваний | |
| EA201690287A1 (ru) | 1,4-дизамещенные аналоги пиридазин хинолина и способы лечения состояний, связанных с smn-дефицитом | |
| JP2011516477A5 (enExample) | ||
| NZ714963A (en) | Compositions and methods for treating anemia | |
| BR112015010396A2 (pt) | terapia de combinação | |
| HK1198869A1 (en) | Combination treatments for hepatitis c | |
| IL292465B2 (en) | Neuroactive compounds and methods of use thereof | |
| HRP20171648T1 (hr) | Supstituirani piperidil-etil-pirimidin kao inhibitor grelin-o-acil-transferaze | |
| ME02405B (me) | Spojevi pirazola као inhibitori sglt1 | |
| EA201400064A1 (ru) | Офтальмологическая фармацевтическая композиция для местного применения, которая содержит регорафениб | |
| JP2016512247A5 (enExample) | ||
| EA201490573A1 (ru) | Соединение бензотиазолона | |
| EA201591653A1 (ru) | Композиции для лечения глазных расстройств с применением дипиридамола |