ES2602051T3 - Anticuerpos biespecíficos contra CD3epsilon y BCMA - Google Patents
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- ES2602051T3 ES2602051T3 ES15179545.7T ES15179545T ES2602051T3 ES 2602051 T3 ES2602051 T3 ES 2602051T3 ES 15179545 T ES15179545 T ES 15179545T ES 2602051 T3 ES2602051 T3 ES 2602051T3
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3061—Blood cells
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
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- C—CHEMISTRY; METALLURGY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C—CHEMISTRY; METALLURGY
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/565—Complementarity determining region [CDR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
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- C—CHEMISTRY; METALLURGY
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
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- Cell Biology (AREA)
- Hematology (AREA)
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- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14179705.0A EP2982692A1 (en) | 2014-08-04 | 2014-08-04 | Bispecific antibodies against CD3epsilon and BCMA |
| EP14179705 | 2014-08-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2602051T3 true ES2602051T3 (es) | 2017-02-17 |
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| ES15179545.7T Active ES2602051T3 (es) | 2014-08-04 | 2015-08-03 | Anticuerpos biespecíficos contra CD3epsilon y BCMA |
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| EP (2) | EP2982692A1 (enExample) |
| JP (2) | JP6703520B2 (enExample) |
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| ES (1) | ES2602051T3 (enExample) |
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| SI (1) | SI2982694T1 (enExample) |
| SM (1) | SMT201600392B (enExample) |
| WO (1) | WO2016020332A1 (enExample) |
Families Citing this family (114)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090162359A1 (en) | 2007-12-21 | 2009-06-25 | Christian Klein | Bivalent, bispecific antibodies |
| WO2010115589A1 (en) | 2009-04-07 | 2010-10-14 | Roche Glycart Ag | Trivalent, bispecific antibodies |
| US9676845B2 (en) | 2009-06-16 | 2017-06-13 | Hoffmann-La Roche, Inc. | Bispecific antigen binding proteins |
| JP5764677B2 (ja) | 2011-02-28 | 2015-08-19 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | 抗原結合タンパク質 |
| CA2824824A1 (en) | 2011-02-28 | 2012-09-07 | F. Hoffmann-La Roche Ag | Monovalent antigen binding proteins |
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2014
- 2014-08-04 EP EP14179705.0A patent/EP2982692A1/en not_active Ceased
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2015
- 2015-08-03 AU AU2015299101A patent/AU2015299101B2/en active Active
- 2015-08-03 PT PT151795457T patent/PT2982694T/pt unknown
- 2015-08-03 LT LTEP15179545.7T patent/LT2982694T/lt unknown
- 2015-08-03 ME MEP-2016-205A patent/ME02533B/me unknown
- 2015-08-03 MA MA39266A patent/MA39266B1/fr unknown
- 2015-08-03 HU HUE15179545A patent/HUE031076T2/en unknown
- 2015-08-03 EP EP15179545.7A patent/EP2982694B1/en active Active
- 2015-08-03 JP JP2017505793A patent/JP6703520B2/ja active Active
- 2015-08-03 SI SI201530004A patent/SI2982694T1/sl unknown
- 2015-08-03 DK DK15179545.7T patent/DK2982694T3/en active
- 2015-08-03 PL PL15179545T patent/PL2982694T3/pl unknown
- 2015-08-03 ES ES15179545.7T patent/ES2602051T3/es active Active
- 2015-08-03 RS RS20160781A patent/RS55410B1/sr unknown
- 2015-08-03 SG SG11201700551TA patent/SG11201700551TA/en unknown
- 2015-08-03 CA CA2955685A patent/CA2955685C/en active Active
- 2015-08-03 US US15/501,620 patent/US10253104B2/en active Active
- 2015-08-03 WO PCT/EP2015/067841 patent/WO2016020332A1/en not_active Ceased
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2016
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- 2016-09-21 HR HRP20161211TT patent/HRP20161211T1/hr unknown
- 2016-10-31 SM SM201600392T patent/SMT201600392B/it unknown
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2020
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- 2020-11-20 AU AU2020273347A patent/AU2020273347A1/en not_active Abandoned
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| CA2955685A1 (en) | 2016-02-11 |
| SMT201600392B (it) | 2017-01-10 |
| CA2955685C (en) | 2023-09-19 |
| RS55410B1 (sr) | 2017-04-28 |
| MA39266B1 (fr) | 2017-01-31 |
| NZ728534A (en) | 2023-12-22 |
| US20170306036A1 (en) | 2017-10-26 |
| AU2015299101B2 (en) | 2020-08-27 |
| MA39266A (fr) | 2016-02-10 |
| HRP20161211T1 (hr) | 2016-11-18 |
| PL2982694T3 (pl) | 2017-02-28 |
| DK2982694T3 (en) | 2016-09-26 |
| HUE031076T2 (en) | 2017-06-28 |
| EP2982694A1 (en) | 2016-02-10 |
| ME02533B (me) | 2017-02-20 |
| HK1218299A1 (en) | 2017-02-10 |
| CY1118168T1 (el) | 2017-06-28 |
| LT2982694T (lt) | 2016-11-10 |
| EP2982692A1 (en) | 2016-02-10 |
| AU2015299101A1 (en) | 2017-02-16 |
| JP6703520B2 (ja) | 2020-06-03 |
| US10253104B2 (en) | 2019-04-09 |
| EP2982694B1 (en) | 2016-06-22 |
| SG11201700551TA (en) | 2017-02-27 |
| SI2982694T1 (sl) | 2017-01-31 |
| AU2020273347A1 (en) | 2020-12-17 |
| JP2020122013A (ja) | 2020-08-13 |
| WO2016020332A1 (en) | 2016-02-11 |
| JP2017532290A (ja) | 2017-11-02 |
| PT2982694T (pt) | 2016-09-29 |
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