ES2204888T3 - Isociclos y heterociclos imidazo-condensados como antagonistas de angiotensina ii. - Google Patents

Isociclos y heterociclos imidazo-condensados como antagonistas de angiotensina ii.

Info

Publication number
ES2204888T3
ES2204888T3 ES92115500T ES92115500T ES2204888T3 ES 2204888 T3 ES2204888 T3 ES 2204888T3 ES 92115500 T ES92115500 T ES 92115500T ES 92115500 T ES92115500 T ES 92115500T ES 2204888 T3 ES2204888 T3 ES 2204888T3
Authority
ES
Spain
Prior art keywords
methyl
compound
ethyl
solution
mmol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92115500T
Other languages
English (en)
Spanish (es)
Inventor
Holger Dr. Heitsch
Adalbert Dr. Wagner
Heinz-Werner Dr. Kleemann
Hermann Dr. Gerhards
Bernward Prof. Dr. Scholkens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19914131325 external-priority patent/DE4131325A1/de
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2204888T3 publication Critical patent/ES2204888T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyridine Compounds (AREA)
  • Detergent Compositions (AREA)
  • Lubricants (AREA)
ES92115500T 1991-09-14 1992-09-10 Isociclos y heterociclos imidazo-condensados como antagonistas de angiotensina ii. Expired - Lifetime ES2204888T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE4130659 1991-09-14
DE4130659 1991-09-14
DE4131325 1991-09-20
DE19914131325 DE4131325A1 (de) 1991-09-20 1991-09-20 Imidazo-annellierte iso und heterocyclen, verfahren zu deren herstellung, sie enthaltende mittel und ihre verwendung

Publications (1)

Publication Number Publication Date
ES2204888T3 true ES2204888T3 (es) 2004-05-01

Family

ID=25907347

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92115500T Expired - Lifetime ES2204888T3 (es) 1991-09-14 1992-09-10 Isociclos y heterociclos imidazo-condensados como antagonistas de angiotensina ii.

Country Status (22)

Country Link
US (2) US5444068A (show.php)
EP (1) EP0533058B1 (show.php)
JP (1) JP3459659B2 (show.php)
KR (1) KR930006020A (show.php)
CN (1) CN1070646A (show.php)
AT (1) ATE247644T1 (show.php)
AU (1) AU659485B2 (show.php)
BR (1) BR9203543A (show.php)
CA (1) CA2078058A1 (show.php)
CZ (1) CZ280492A3 (show.php)
DE (1) DE59209986D1 (show.php)
DK (1) DK0533058T3 (show.php)
ES (1) ES2204888T3 (show.php)
FI (1) FI924054L (show.php)
HU (1) HUT62892A (show.php)
IL (1) IL103141A0 (show.php)
NO (1) NO300326B1 (show.php)
NZ (1) NZ244303A (show.php)
PL (1) PL171766B1 (show.php)
PT (1) PT533058E (show.php)
RU (1) RU2076105C1 (show.php)
TW (1) TW300219B (show.php)

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Also Published As

Publication number Publication date
BR9203543A (pt) 1993-04-13
IL103141A0 (en) 1993-02-21
AU659485B2 (en) 1995-05-18
DE59209986D1 (de) 2003-09-25
FI924054A7 (fi) 1993-03-15
NO923535L (no) 1993-03-15
PT533058E (pt) 2004-01-30
PL171766B1 (pl) 1997-06-30
NZ244303A (en) 1995-12-21
HU9202931D0 (en) 1992-11-30
FI924054A0 (fi) 1992-09-10
TW300219B (show.php) 1997-03-11
NO923535D0 (no) 1992-09-11
US5444068A (en) 1995-08-22
NO300326B1 (no) 1997-05-12
ATE247644T1 (de) 2003-09-15
CN1070646A (zh) 1993-04-07
EP0533058B1 (de) 2003-08-20
DK0533058T3 (da) 2003-11-24
JPH05262742A (ja) 1993-10-12
PL295911A1 (en) 1993-03-22
KR930006020A (ko) 1993-04-20
JP3459659B2 (ja) 2003-10-20
CZ280492A3 (en) 1993-04-14
HUT62892A (en) 1993-06-28
EP0533058A1 (de) 1993-03-24
RU2076105C1 (ru) 1997-03-27
CA2078058A1 (en) 1993-03-15
AU2353392A (en) 1993-03-18
FI924054L (fi) 1993-03-15
US5635525A (en) 1997-06-03

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