ES2007625A6 - Un procedimiento para la produccion de una proteina para huesos y cartilagos. - Google Patents
Un procedimiento para la produccion de una proteina para huesos y cartilagos.Info
- Publication number
- ES2007625A6 ES2007625A6 ES8701909A ES8701909A ES2007625A6 ES 2007625 A6 ES2007625 A6 ES 2007625A6 ES 8701909 A ES8701909 A ES 8701909A ES 8701909 A ES8701909 A ES 8701909A ES 2007625 A6 ES2007625 A6 ES 2007625A6
- Authority
- ES
- Spain
- Prior art keywords
- osteoinductive compositions
- novel osteoinductive
- novel
- compositions
- bone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title 1
- 230000002138 osteoinductive effect Effects 0.000 title 1
- 210000000988 bone and bone Anatomy 0.000 abstract 2
- 241000283690 Bos taurus Species 0.000 abstract 1
- 230000007547 defect Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000003239 periodontal effect Effects 0.000 abstract 1
- 238000010188 recombinant method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/043—Mixtures of macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Toxicology (AREA)
- Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Indole Compounds (AREA)
- Materials For Medical Uses (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Photoreceptors In Electrophotography (AREA)
- Medicinal Preparation (AREA)
- Compounds Of Unknown Constitution (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88077686A | 1986-07-01 | 1986-07-01 | |
| US94333286A | 1986-12-17 | 1986-12-17 | |
| US2828587A | 1987-03-20 | 1987-03-20 | |
| US07/031,346 US4877864A (en) | 1987-03-26 | 1987-03-26 | Osteoinductive factors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2007625A6 true ES2007625A6 (es) | 1989-07-01 |
Family
ID=27487661
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8701909A Expired ES2007625A6 (es) | 1986-07-01 | 1987-06-30 | Un procedimiento para la produccion de una proteina para huesos y cartilagos. |
Country Status (18)
| Country | Link |
|---|---|
| EP (3) | EP0688869B1 (enExample) |
| JP (3) | JP2713715B2 (enExample) |
| AT (3) | ATE419349T1 (enExample) |
| AU (1) | AU613314B2 (enExample) |
| CA (1) | CA1341212C (enExample) |
| DE (4) | DE10399007I2 (enExample) |
| DK (2) | DK172275B1 (enExample) |
| ES (1) | ES2007625A6 (enExample) |
| GR (1) | GR871028B (enExample) |
| IE (1) | IE75881B1 (enExample) |
| IL (1) | IL83003A (enExample) |
| LU (1) | LU91005I2 (enExample) |
| MX (1) | MX170919B (enExample) |
| MY (1) | MY102505A (enExample) |
| NL (1) | NL300116I2 (enExample) |
| NZ (1) | NZ220894A (enExample) |
| PT (1) | PT85225B (enExample) |
| WO (1) | WO1988000205A1 (enExample) |
Families Citing this family (131)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5106748A (en) * | 1986-07-01 | 1992-04-21 | Genetics Institute, Inc. | Dna sequences encoding 5 proteins |
| IL83003A (en) * | 1986-07-01 | 1995-07-31 | Genetics Inst | Osteoinductive factors |
| US6150328A (en) * | 1986-07-01 | 2000-11-21 | Genetics Institute, Inc. | BMP products |
| US6020313A (en) * | 1987-10-09 | 2000-02-01 | University Of Kansas | Method for inducing bone formation using an extract of human osteosarcoma cell line SAOS-2 |
| US5035901A (en) * | 1987-10-09 | 1991-07-30 | University Of Kansas | Bone inducing agent from a human osteosarcoma cell line |
| US4975526A (en) * | 1989-02-23 | 1990-12-04 | Creative Biomolecules, Inc. | Bone collagen matrix for zenogenic implants |
| US5258494A (en) | 1988-04-08 | 1993-11-02 | Stryker Corporation | Osteogenic proteins |
| US5354557A (en) * | 1988-04-08 | 1994-10-11 | Stryker Corporation | Osteogenic devices |
| US5324819A (en) * | 1988-04-08 | 1994-06-28 | Stryker Corporation | Osteogenic proteins |
| US6586388B2 (en) | 1988-04-08 | 2003-07-01 | Stryker Corporation | Method of using recombinant osteogenic protein to repair bone or cartilage defects |
| US5266683A (en) * | 1988-04-08 | 1993-11-30 | Stryker Corporation | Osteogenic proteins |
| US5344654A (en) * | 1988-04-08 | 1994-09-06 | Stryker Corporation | Prosthetic devices having enhanced osteogenic properties |
| US5108753A (en) * | 1988-04-08 | 1992-04-28 | Creative Biomolecules | Osteogenic devices |
| US5162114A (en) * | 1989-02-23 | 1992-11-10 | Stryker Corporation | Bone collagen matrix for xenogenic implants |
| US4968590A (en) * | 1988-04-08 | 1990-11-06 | Stryker Corporation | Osteogenic proteins and polypeptides |
| US5250302A (en) * | 1988-04-08 | 1993-10-05 | Stryker Corporation | Osteogenic devices |
| ATE142644T1 (de) * | 1988-04-08 | 1996-09-15 | Stryker Corp | Biosynthetische osteogene proteine und sie enthaltende osteogene vorrichtungen |
| EP0408649A4 (en) * | 1988-04-08 | 1991-11-27 | Genetics Institute, Inc. | Bone and cartilage inductive compositions |
| US6919308B2 (en) | 1988-04-08 | 2005-07-19 | Stryker Corporation | Osteogenic devices |
| US5670336A (en) * | 1988-04-08 | 1997-09-23 | Stryker Corporation | Method for recombinant production of osteogenic protein |
| US5106626A (en) * | 1988-10-11 | 1992-04-21 | International Genetic Engineering, Inc. | Osteogenic factors |
| US5284756A (en) * | 1988-10-11 | 1994-02-08 | Lynn Grinna | Heterodimeric osteogenic factor |
| US4915301A (en) * | 1988-11-15 | 1990-04-10 | International Flavors & Fragrances, Inc. | Container with sorbent member and microporous membrane for dispensing vapor from volatile liquid |
| DK0429570T3 (da) * | 1989-03-28 | 1998-04-27 | Genetics Inst | Osteoinducerende præparater |
| JP3504259B2 (ja) | 1989-03-28 | 2004-03-08 | ジェネティックス・インスチチュート・リミテッド・ライアビリティ・カンパニー | 骨誘導組成物 |
| JPH03151877A (ja) * | 1989-06-02 | 1991-06-28 | Chiron Corp | 骨カルシウム沈着因子 |
| CA2020729A1 (en) * | 1989-07-19 | 1991-01-20 | Michael C. Kiefer | Bone morphogenetic protein |
| CA2064878A1 (en) * | 1989-08-21 | 1991-02-22 | Hanne Bentz | Bone-specific protein |
| ATE140965T1 (de) * | 1989-09-06 | 1996-08-15 | Takeda Chemical Industries Ltd | Protein, dna und ihre verwendung |
| EP0448704B1 (en) * | 1989-10-17 | 1998-06-17 | Stryker Corporation | Osteogenic devices |
| US5168050A (en) * | 1990-05-24 | 1992-12-01 | Genentech, Inc. | Mammalian expression of the bone morphogenetic protein-2b using bmp2a/bmp2b fusion |
| US5645591A (en) | 1990-05-29 | 1997-07-08 | Stryker Corporation | Synthetic bone matrix |
| US5364839A (en) * | 1990-06-18 | 1994-11-15 | Genetics Institute, Inc. | Osteoinductive pharmaceutical formulations |
| ATE253589T1 (de) * | 1990-09-26 | 2003-11-15 | Inst Genetics Llc | Bmp-5-derivate |
| US5206023A (en) * | 1991-01-31 | 1993-04-27 | Robert F. Shaw | Method and compositions for the treatment and repair of defects or lesions in cartilage |
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| US20110224410A1 (en) | 2009-09-17 | 2011-09-15 | Hile David | Buffers for Controlling the pH of Bone Morphogenetic Proteins |
| CN102822197A (zh) | 2009-12-22 | 2012-12-12 | 史赛克公司 | 具有降低的免疫原性的bmp-7变体 |
| JP2020504748A (ja) | 2016-12-30 | 2020-02-13 | バイオジェンド セラピューティクス カンパニー リミテッド | 組換えポリペプチド、それらの組成物及び方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4619989A (en) * | 1981-05-05 | 1986-10-28 | The Regents Of The University Of Cal. | Bone morphogenetic protein composition |
| US4455256A (en) * | 1981-05-05 | 1984-06-19 | The Regents Of The University Of California | Bone morphogenetic protein |
| US4419446A (en) | 1980-12-31 | 1983-12-06 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant DNA process utilizing a papilloma virus DNA as a vector |
| US4434094A (en) * | 1983-04-12 | 1984-02-28 | Collagen Corporation | Partially purified osteogenic factor and process for preparing same from demineralized bone |
| US4588684A (en) | 1983-04-26 | 1986-05-13 | Chiron Corporation | a-Factor and its processing signals |
| CA1229789A (en) * | 1983-06-06 | 1987-12-01 | David Baylink | Polypeptides exhibiting skeletal growth factor activity |
| US4795804A (en) * | 1983-08-16 | 1989-01-03 | The Regents Of The University Of California | Bone morphogenetic agents |
| NZ210699A (en) * | 1984-01-04 | 1989-06-28 | Int Genetic Eng | Isolation of an osteogenic protein of the p3 immunologically related family |
| DK518384A (da) | 1984-01-31 | 1985-07-01 | Idaho Res Found | Vektor til fremstilling af et gen-produkt i insektceller, fremgangsmaade til dens fremstilling samt dens anvendelse |
| US4608199A (en) * | 1984-03-20 | 1986-08-26 | Arnold Caplan | Bone protein purification process |
| IE60819B1 (en) | 1984-07-06 | 1994-08-10 | Sandoz Ltd | Lymphokine production and purification |
| DE3588058T3 (de) | 1984-07-16 | 2005-04-07 | Celtrix Pharmaceuticals, Inc., Palo Alto | Knorpel-induzierende Polypeptid-Faktoren aus Knochen |
| ATE78515T1 (de) | 1984-10-05 | 1992-08-15 | Genentech Inc | Dna, zellkulturen und verfahren zur sekretion von heterologen proteinen und periplasmische proteinrueckgewinnung. |
| US4563350A (en) * | 1984-10-24 | 1986-01-07 | Collagen Corporation | Inductive collagen based bone repair preparations |
| IL83003A (en) * | 1986-07-01 | 1995-07-31 | Genetics Inst | Osteoinductive factors |
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1987
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- 1987-06-29 IE IE173987A patent/IE75881B1/en not_active IP Right Cessation
- 1987-06-30 GR GR871028A patent/GR871028B/el unknown
- 1987-06-30 DE DE2003199007 patent/DE10399007I2/de active Active
- 1987-06-30 JP JP62504617A patent/JP2713715B2/ja not_active Expired - Lifetime
- 1987-06-30 EP EP95111771A patent/EP0688869B1/en not_active Expired - Lifetime
- 1987-06-30 MY MYPI87000921A patent/MY102505A/en unknown
- 1987-06-30 DE DE3752364T patent/DE3752364T2/de not_active Expired - Lifetime
- 1987-06-30 MX MX007140A patent/MX170919B/es unknown
- 1987-06-30 EP EP02014841A patent/EP1254956B1/en not_active Expired - Lifetime
- 1987-06-30 DE DE3751887T patent/DE3751887T2/de not_active Expired - Lifetime
- 1987-06-30 WO PCT/US1987/001537 patent/WO1988000205A1/en not_active Ceased
- 1987-06-30 ES ES8701909A patent/ES2007625A6/es not_active Expired
- 1987-06-30 AT AT02014841T patent/ATE419349T1/de not_active IP Right Cessation
- 1987-06-30 AU AU77835/87A patent/AU613314B2/en not_active Expired
- 1987-06-30 EP EP87905023A patent/EP0313578B1/en not_active Expired - Lifetime
- 1987-06-30 NZ NZ220894A patent/NZ220894A/xx unknown
- 1987-06-30 AT AT87905023T patent/ATE141928T1/de active
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- 1987-06-30 CA CA000540928A patent/CA1341212C/en not_active Expired - Fee Related
- 1987-06-30 DE DE3752393T patent/DE3752393D1/de not_active Expired - Lifetime
- 1987-07-01 PT PT85225A patent/PT85225B/pt unknown
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1988
- 1988-02-29 DK DK106288A patent/DK172275B1/da not_active IP Right Cessation
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1993
- 1993-06-01 JP JP5130389A patent/JP2729222B2/ja not_active Expired - Lifetime
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1997
- 1997-05-09 DK DK199700534A patent/DK172503B1/da not_active IP Right Cessation
- 1997-06-27 JP JP09171615A patent/JP3093682B2/ja not_active Expired - Lifetime
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2003
- 2003-01-29 LU LU91005C patent/LU91005I2/fr unknown
- 2003-02-24 NL NL300116C patent/NL300116I2/nl unknown
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