EP0679380A1 - Dispositif de transfert et de prélèvement de fluides hors de bouteilles, poches ou récipients similaires dans un but médical - Google Patents

Dispositif de transfert et de prélèvement de fluides hors de bouteilles, poches ou récipients similaires dans un but médical Download PDF

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Publication number
EP0679380A1
EP0679380A1 EP19950250097 EP95250097A EP0679380A1 EP 0679380 A1 EP0679380 A1 EP 0679380A1 EP 19950250097 EP19950250097 EP 19950250097 EP 95250097 A EP95250097 A EP 95250097A EP 0679380 A1 EP0679380 A1 EP 0679380A1
Authority
EP
European Patent Office
Prior art keywords
rotationally symmetrical
piercing
flow channel
symmetrical body
filter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP19950250097
Other languages
German (de)
English (en)
Other versions
EP0679380B1 (fr
Inventor
Klaus Pfleiderer
Peter Heise
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CareMed Medical Produkte AG
Original Assignee
Care Med Vertrieb Med Lab GmbH
Care Med Vertrieb Med-Lab Produkte GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Care Med Vertrieb Med Lab GmbH, Care Med Vertrieb Med-Lab Produkte GmbH filed Critical Care Med Vertrieb Med Lab GmbH
Publication of EP0679380A1 publication Critical patent/EP0679380A1/fr
Application granted granted Critical
Publication of EP0679380B1 publication Critical patent/EP0679380B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2089—Containers or vials which are to be joined to each other in order to mix their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/201—Piercing means having one piercing end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/2013—Piercing means having two piercing ends
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2068—Venting means
    • A61J1/2072—Venting means for internal venting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2068—Venting means
    • A61J1/2075—Venting means for external venting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2079—Filtering means
    • A61J1/2082—Filtering means for gas filtration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2079—Filtering means
    • A61J1/2086—Filtering means for fluid filtration
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/794—With means for separating solid material from the fluid
    • Y10T137/8122—Planar strainer normal to flow path
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/8593—Systems
    • Y10T137/86292—System with plural openings, one a gas vent or access opening
    • Y10T137/86324—Tank with gas vent and inlet or outlet
    • Y10T137/86332—Vent and inlet or outlet in unitary mounting

Definitions

  • the invention relates to a device for transferring and removing liquids from bottles, bags or similar containers for medical purposes with practically on one axis, diagonally opposite piercing spikes, in each of which two flow channels are present. Such devices are also referred to as transfer spikes.
  • DE 3627231 A1 describes a transfer device for mixing medications located in different containers, consisting of two piercing spikes directed in opposite directions and connected to one another, each of which is provided with a continuous liquid channel and a ventilation channel, and which is characterized in that the Transfer device consists of two components that can be coupled to one another, each component being provided with a piercing mandrel and the liquid channels being connected to one another in the coupled state, while each ventilation channel ends in a ventilation opening with an interposed filter.
  • This device is not only complicated to manufacture and handle, but also has the disadvantage that two air filters are required. In addition, there is no possibility of keeping the remaining liquid to be used closed in the storage vessel.
  • DE 3820204 A1 describes a device for the filtered supply or removal of liquid into or from a container, in particular a bottle, in which separate chambers for the liquid channel and the air channel are arranged in a carrier plate, each containing filter elements.
  • the device has the disadvantage of complicated manufacture and handling.
  • This device is therefore only suitable as a removal and not as a transfer spike.
  • DE 4122221 A1 describes a transfer and removal spike in which a carrier plate is provided with piercing mandrels arranged diametrically to one another, through which two flow channels are guided, with which a shut-off element cooperates, which in an open position releases the flow through the flow channel and blocks the flow through the flow channel in a blocking position, a liquid removal channel in Flow connection with a portion of the flow channel open to an injection syringe arrives and the liquid removal channel opens into a connecting piece.
  • This device is not only complicated to manufacture, but also in terms of operation and functional reliability. Furthermore, massive tightness problems between the carrier plate and the shut-off element are to be expected during manufacture and handling. Here too, the bottle can only be sealed with the residual liquid at great expense.
  • DE 4010202 A1 describes a removal spike which consists of a carrier plate and a piercing mandrel, which forms a structural unit with a connecting piece and a filter element is welded to the carrier plate in the region of the inlet opening. With this device, only removal, but no transfer, is possible.
  • a device for transferring and removing liquids from bottles, bags or similar containers which not only allows two media to be mixed quickly, but also to store residual quantities and enables the targeted removal of partial quantities.
  • With regard to environmentally friendly production and disposal it should consist of as few and small components as possible with low weight.
  • the rotationally symmetrical bodies are U-shaped.
  • the U-shaped design is designed such that a cylindrical guide and seal is arranged on the larger diameter, while a conical guide and seal is arranged on the inside in the region of the smaller diameter.
  • an air filter known per se, circular or in another suitable form is advantageously arranged on the inner rotationally symmetrical body. Furthermore, it is advantageous that, in order to separate the two rotationally symmetrical bodies in the region of the smaller diameter, cams in connection with radially extending inclined planes are arranged with a rotation range of preferably 90 °. To additionally secure the connection of the two rotationally symmetrical bodies, two or more snap hooks distributed symmetrically on the circumference are arranged in the region of the larger diameter of the rotationally symmetrical body.
  • a liquid filter is advantageously accommodated in a filter housing, which consists of a lower part and an upper part.
  • the filter housing is connected to the lower attachment of the smaller rotationally symmetrical body via an upper part with a thread.
  • the filter housing is sealed off from the smaller, rotationally symmetrical body in the area of the liquid outlet, ie at the lower attachment by means of a conical sealing surface.
  • the lower part of the filter housing is connected directly to the smaller rotationally symmetrical body, e.g. glued or welded.
  • a threaded cam is provided at the end of the lower part, via which a conventional syringe or an infusion line can be attached or the holder of the protective cap is used for the closed storage of the residual liquid.
  • the protective cap serving to protect the piercing mandrel on a connecting part. After piercing, this protective cap is used to close the smaller rotationally symmetrical body or the lower part of the filter housing and thus to protect the liquid to be stored.
  • An advantageous variant of the invention consists in not only allowing the air exchange between the medical containers to take place via the flow channel with the air filter, but also directing it via a further flow channel.
  • the rotationally symmetrical bodies separated from each other by a rotating movement across the inclined plane.
  • the cam presses a cover with a plug into the further flow channel and thereby closes it airtight.
  • a check valve or another equivalent device can expediently be provided. It has proven to be an advantageous variant in the embodiment of the invention to provide the flow channel at the tip of the piercing mandrel with a capillary-like constriction. Instead of the constriction, a cap, a valve, a filter or another suitable device can also be used.
  • the solution according to the invention has a number of decisive advantages. It is thus possible to dissolve a mostly toxic dry substance with a liquid in a closed system without aerosols escaping into the environment and thus without any risk for the user or the patient. Aeration of the containers during the liquid transfer is possible in a simple manner. After mixing, the solution is drawn off by means of a syringe or an infusion line, possibly with an integrated drip chamber, after the smaller body has been separated from the larger, rotationally symmetrical body.
  • a particular advantage is that the two containers can be separated with a single movement and the container with the usable solution is thus available separately.
  • the device according to the invention is simple and inexpensive to manufacture. It has a small volume and thus generates little waste. It is also easy to handle, which is a great advantage in clinical operations. Due to the modular construction, a transfer set and a simple spike for withdrawing a solution from a container with a secure closure of the container and thus for safe storage of unnecessary solution quantities are possible with the invention. By rotating one of the two rotationally symmetrical bodies, the two containers can be separated quickly and easily. This simple and safe handling is made possible by the anti-twist protection of the spikes in the rubber-elastic plugs of the containers. The invention will be explained in more detail using an exemplary embodiment and the drawing.
  • FIG. 1 the overall view of the device according to the invention is shown.
  • the essential features of the invention become clear from the sectional illustration according to FIGS. 2 to 5a.
  • the two rotationally symmetrical bodies 3 and 4 which form a physical unit with the piercing mandrels 1 and 2, each adjoin two diametrically opposed piercing mandrels 1 and 2, which are generally rotationally symmetrical. Both rotationally symmetrical bodies 3 and 4 can be plugged into one another centrally.
  • the rotationally symmetrical body 4 engages over the rotationally symmetrical body 3. Both are U-shaped and are provided with an annular guide and seal 5 on the largest diameter. A conical guide and seal 6 are also provided at the opposite end of the two rotationally symmetrical bodies 3 and 4. With this construction, the two rotationally symmetrical bodies 3 and 4 are centered and sealed from one another. To the two rotationally symmetrical To be able to detach bodies 3 and 4 again, two to three threaded cams 7 are advantageously distributed around the circumference at the lower end of the smaller rotationally symmetrical body 3, which, when the two rotationally symmetrical bodies 3 and 4 are rotated, slide by preferably 90 ° over inclined planes 8 and thus generate a rotary stroke movement to separate the connection.
  • the rotatability is indicated by the arrow 9 in FIG. 2b.
  • Two flow channels 12a and 13a or 12b and 13b are respectively arranged in the piercing mandrels 1 and 2.
  • the arrangement of the flow channels 12a and 12b is such that they practically form an axial passage in the device according to the invention, so that, for. B. can get a liquid medium without additional flow resistance from the bottle 10 into the bottle 11.
  • bottles 10; 11 instead of the bottles 10; 11, other containers or syringes or infusion lines known for medical purposes can also be used.
  • the flow channels 13a and 13b are connected via an annular gap-shaped recess 14 formed between the rotationally symmetrical bodies 3 and 4
  • a cutout 15 for example a bore, is arranged at the end of the flow channel 13a perpendicular to the longitudinal axis, with the interposition of an air filter 16 known per se the recess 14 is connected.
  • An additional or alternative non-positive connection of the rotationally symmetrical bodies 3 and 4 is possible by means of snap hooks 17, which are arranged on the circumference of the larger rotationally symmetrical body 4 and overlap the circular surface of the rotationally symmetrical body 3 (cf. FIG. 3).
  • the protective caps 18 and 19 are provided with protective caps 18 and 19. While the protective cap 18 is discarded, the protective cap 19 is connected to the device according to the invention via a flexible connecting element 20. After separating the device according to the invention, the remaining solution can be stored in the bottle 11 with the protective cap 19 which is pushed over the threaded cams 7. Part of the solution can thus be removed at any time via a syringe 21.
  • these can expediently be oval or in another non-rotationally symmetrical shape or be provided with ribs 22 which are distributed along the circumference and extend in the longitudinal direction.
  • FIG. 1 Another advantageous embodiment of the device according to the invention which corresponds to the modular principle consists in the following. If after transferring the solvent from the bottle 10 into the bottle 11, the bottle 10 together with the larger rotationally symmetrical body 4 of is separated from the smaller rotationally symmetrical body 3, a filter housing is attached to the smaller rotationally symmetrical body 3 via the threaded cams 7 and a thread 26 located at the base.
  • the filter housing consists of an upper part 24 and a lower part 25 as well as a filter 23, which is known per se and arranged transversely to the flow direction.
  • the sealing surface 28 is produced by means of a conical extension which engages in the end of the smaller rotationally symmetrical body 3.
  • a syringe 21 can be attached via a threaded cam 27, which corresponds to the cam 7, and the content of the bottle 11 can be filtered out (see FIG. 5).
  • the modular principle which the invention follows in the design of its individual parts, enables a pure removal spike for the filtered removal of liquids from the smaller, rotationally symmetrical body 3 by direct attachment of the filter 23 in connection with the lower part 25 of the filter housing, for example by welding or to produce solutions for medical purposes (see FIG. 5a). It has been shown that the liquid transport from bottle 10 to bottle 11 is generally too slow when used as a transfer spike (see FIGS. 2 and 6a).
  • the reason for this is that the air exchange from the bottle 11 to the bottle 10 via the air filter 16 has too high a resistance at the relatively small pressure difference. Since the rotationally symmetrical bodies 3 and 4, due to the areal seals 5 and 6, do not allow any air exchange of the interior with the surroundings, the air exchange can expediently also take place in a different way than via the air filter 16 (see FIG. 2e).
  • the air from the bottle 11 not only enters the bottle 10 via the cutout 14, the air filter 16, the cutout 15 and the flow channel 13a, but can also travel directly from the cutout 14 via the cutout 29, the flow channel 30 to the cutout 15 and continue via flow channel 13a to bottle 10.
  • the rotationally symmetrical bodies 3 and 4 are separated from one another by a rotating movement over the inclined planes 8.
  • the cam 31 presses the cover 32 shut and the plug 33 closes the flow channel 30 in an airtight manner.
  • the rotary movement should cover an angle of preferably 30 ° to 45 °.
  • gas exchange can then only take place via the air filter 16.
  • another pluggable closure of the flow channel 30 is also possible, which can also be located at another location on the rotationally symmetrical body 3.
  • the Closure of the flow channel 30 via a check valve or another suitable measure.
  • a constriction 13a1 of one to ten millimeters in length and a diameter of preferably 0.2 to 0.6 millimeters has proven to be particularly advantageous.
  • a flap, a valve or another suitable device can also be used.

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Loading And Unloading Of Fuel Tanks Or Ships (AREA)
EP19950250097 1994-04-27 1995-04-26 Dispositif de transfert et de prélèvement de fluides hors de bouteilles, poches ou récipients similaires dans un but médical Expired - Lifetime EP0679380B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19944414697 DE4414697C2 (de) 1994-04-27 1994-04-27 Vorrichtung zum Transferieren und Entnehmen von Flüssigkeiten aus Flaschen, Beuteln oder ähnlichen Behältnissen für medizinische Zwecke
DE4414697 1994-04-27

Publications (2)

Publication Number Publication Date
EP0679380A1 true EP0679380A1 (fr) 1995-11-02
EP0679380B1 EP0679380B1 (fr) 1998-06-17

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EP19950250097 Expired - Lifetime EP0679380B1 (fr) 1994-04-27 1995-04-26 Dispositif de transfert et de prélèvement de fluides hors de bouteilles, poches ou récipients similaires dans un but médical

Country Status (4)

Country Link
US (1) US5636660A (fr)
EP (1) EP0679380B1 (fr)
DE (2) DE4414697C2 (fr)
ES (1) ES2120126T3 (fr)

Cited By (2)

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Publication number Priority date Publication date Assignee Title
FR2753624A1 (fr) * 1996-09-25 1998-03-27 Biodome Dispositif de connexion, en particulier entre un recipient avec bouchon perforable et une seringue
EP1498097A3 (fr) * 2003-07-17 2005-02-16 Nipro Corporation Aiguille de transfert

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IL114960A0 (en) * 1995-03-20 1995-12-08 Medimop Medical Projects Ltd Flow control device
SE509950C2 (sv) * 1995-05-02 1999-03-29 Carmel Pharma Ab Anordning för administrering av toxisk vätska
DE29520388U1 (de) * 1995-12-22 1997-04-24 Froer Werner Rohrförmiges Leitungsteil mit einem Schwimmerventil und Formwerkzeug zum Herstellen desselben
FR2783808B1 (fr) 1998-09-24 2000-12-08 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
DE19927201A1 (de) * 1999-06-15 2001-01-25 Schott Glas Spritze für medizinische Zwecke
FR2802183B1 (fr) * 1999-12-10 2002-02-22 Biodome Procede de fabrication d'un dispositif de connexion entre un recipient et un contenant, dispositif de connexion correspondant et ensemble pret a l'emploi comprenant un tel dispositif
US7799009B2 (en) * 2000-01-24 2010-09-21 Bracco Diagnostics Inc. Tabletop drug dispensing vial access adapter
US6544246B1 (en) 2000-01-24 2003-04-08 Bracco Diagnostics, Inc. Vial access adapter and vial combination
US6832994B2 (en) * 2000-01-24 2004-12-21 Bracco Diagnostics Inc. Table top drug dispensing vial access adapter
US6503240B1 (en) 2000-01-24 2003-01-07 Brocco Diagnostics, Inc. Vial access adapter
US6139534A (en) * 2000-01-24 2000-10-31 Bracco Diagnostics, Inc. Vial access adapter
DE20003058U1 (de) * 2000-02-19 2000-04-13 Braun Melsungen Ag Transfer- und Entnahmevorrichtung für medizinische Flüssigkeiten
FR2815328B1 (fr) * 2000-10-17 2002-12-20 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
US6558365B2 (en) * 2001-01-03 2003-05-06 Medimop Medical Projects, Ltd. Fluid transfer device
FR2821827B1 (fr) * 2001-03-07 2003-06-13 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
FR2836129B1 (fr) 2002-02-20 2004-04-02 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
US7121808B2 (en) * 2002-11-15 2006-10-17 Hill-Rom Services, Inc. High frequency air pulse generator
US6948522B2 (en) * 2003-06-06 2005-09-27 Baxter International Inc. Reconstitution device and method of use
IL161660A0 (en) 2004-04-29 2004-09-27 Medimop Medical Projects Ltd Liquid drug delivery device
US20080045919A1 (en) * 2004-12-23 2008-02-21 Bracco Research S.A. Liquid Transfer Device for Medical Dispensing Containers
WO2006076492A2 (fr) * 2005-01-13 2006-07-20 Whatman, Inc. Dispositif et procede de transfert et de reconstitution
ES2371557T3 (es) 2005-08-11 2012-01-05 Medimop Medical Projects Ltd. Dispositivos de transferencia de fármacos líquidos para un correcto ajuste a presión a prueba de fallos en viales medicinales.
EP1797919A1 (fr) * 2005-12-16 2007-06-20 Bracco Research S.A. Dispositif pour le transfert de liquides pour récipient de distribution de médicaments
NZ573048A (en) 2006-05-25 2011-08-26 Bayer Healthcare Llc Reconstitution device
IL182605A0 (en) 2007-04-17 2007-07-24 Medimop Medical Projects Ltd Fluid control device with manually depressed actuator
WO2009026443A2 (fr) * 2007-08-21 2009-02-26 Gilero, Llc Système d'accès à un flacon et d'injection
CN101918074B (zh) 2007-09-18 2013-02-27 麦迪麦珀医疗工程有限公司 药物混合及注射装置和药物混合方法
IL186290A0 (en) 2007-09-25 2008-01-20 Medimop Medical Projects Ltd Liquid drug delivery devices for use with syringe having widened distal tip
WO2009146088A1 (fr) * 2008-04-01 2009-12-03 Yukon Medical, Llc Dispositif de transfert de fluide à contenant double
DE102008020652A1 (de) * 2008-04-24 2009-12-31 Plümat Plate & Lübeck GmbH & Co. Durchstoßvorrichtung und Verfahren zum Entnehmen einer Flüssigkeit aus einem Beutel oder Zuführen einer Substanz in einen Beutel
USD641080S1 (en) 2009-03-31 2011-07-05 Medimop Medical Projects Ltd. Medical device having syringe port with locking mechanism
JP5685579B2 (ja) 2009-04-14 2015-03-18 ユーコン・メディカル，リミテッド・ライアビリティ・カンパニー 流体移送装置
USD616984S1 (en) 2009-07-02 2010-06-01 Medimop Medical Projects Ltd. Vial adapter having side windows
USD630732S1 (en) 2009-09-29 2011-01-11 Medimop Medical Projects Ltd. Vial adapter with female connector
IL201323A0 (en) 2009-10-01 2010-05-31 Medimop Medical Projects Ltd Fluid transfer device for assembling a vial with pre-attached female connector
IL202070A0 (en) 2009-11-12 2010-06-16 Medimop Medical Projects Ltd Inline liquid drug medical device
IL202069A0 (en) 2009-11-12 2010-06-16 Medimop Medical Projects Ltd Fluid transfer device with sealing arrangement
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BR112012021134B1 (pt) 2010-02-24 2020-01-21 Medimop Medical Projects Ltd conjunto de transferência de fluido para uso com um primeiro frasco e um segundo frasco para fins de reconstituição e administração de droga líquida
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FR2753624A1 (fr) * 1996-09-25 1998-03-27 Biodome Dispositif de connexion, en particulier entre un recipient avec bouchon perforable et une seringue
WO1998013006A1 (fr) * 1996-09-25 1998-04-02 Biodome Dispositif de connexion, en particulier entre un recipient avec bouchon perforable et une seringue
US6070623A (en) * 1996-09-25 2000-06-06 Biodome Connecting device, in particular between a receptacle with a stopper capable of being perforated and a syringe
EP1498097A3 (fr) * 2003-07-17 2005-02-16 Nipro Corporation Aiguille de transfert
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Also Published As

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US5636660A (en) 1997-06-10
ES2120126T3 (es) 1998-10-16
DE4414697C2 (de) 1998-06-18
EP0679380B1 (fr) 1998-06-17
DE59502557D1 (de) 1998-07-23
DE4414697A1 (de) 1995-11-02

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