EG24081A - 4-Substituted-9-deoxo-9a-aza-9a-homerythromycin derivatives - Google Patents

4-Substituted-9-deoxo-9a-aza-9a-homerythromycin derivatives

Info

Publication number
EG24081A
EG24081A EG64098A EG64098A EG24081A EG 24081 A EG24081 A EG 24081A EG 64098 A EG64098 A EG 64098A EG 64098 A EG64098 A EG 64098A EG 24081 A EG24081 A EG 24081A
Authority
EG
Egypt
Prior art keywords
homerythromycin
deoxo
aza
derivatives
substituted
Prior art date
Application number
EG64098A
Other languages
English (en)
Inventor
Brians S Bronk
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21959336&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EG24081(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Application granted granted Critical
Publication of EG24081A publication Critical patent/EG24081A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
EG64098A 1997-06-11 1998-06-09 4-Substituted-9-deoxo-9a-aza-9a-homerythromycin derivatives EG24081A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4934897P 1997-06-11 1997-06-11

Publications (1)

Publication Number Publication Date
EG24081A true EG24081A (en) 2008-05-11

Family

ID=21959336

Family Applications (1)

Application Number Title Priority Date Filing Date
EG64098A EG24081A (en) 1997-06-11 1998-06-09 4-Substituted-9-deoxo-9a-aza-9a-homerythromycin derivatives

Country Status (49)

Country Link
US (4) US6420536B1 (cg-RX-API-DMAC10.html)
EP (1) EP0988310B9 (cg-RX-API-DMAC10.html)
JP (2) JP3315704B2 (cg-RX-API-DMAC10.html)
KR (1) KR100396168B1 (cg-RX-API-DMAC10.html)
CN (4) CN1172947C (cg-RX-API-DMAC10.html)
AP (1) AP1231A (cg-RX-API-DMAC10.html)
AR (1) AR013086A1 (cg-RX-API-DMAC10.html)
AT (1) ATE251173T1 (cg-RX-API-DMAC10.html)
AU (1) AU749816B2 (cg-RX-API-DMAC10.html)
BG (1) BG64391B1 (cg-RX-API-DMAC10.html)
BR (1) BRPI9810519B8 (cg-RX-API-DMAC10.html)
CA (1) CA2293823C (cg-RX-API-DMAC10.html)
CO (1) CO4950611A1 (cg-RX-API-DMAC10.html)
CZ (1) CZ298556B6 (cg-RX-API-DMAC10.html)
DE (2) DE122004000018I2 (cg-RX-API-DMAC10.html)
DK (1) DK0988310T3 (cg-RX-API-DMAC10.html)
DZ (1) DZ2514A1 (cg-RX-API-DMAC10.html)
EA (1) EA002441B1 (cg-RX-API-DMAC10.html)
EG (1) EG24081A (cg-RX-API-DMAC10.html)
ES (1) ES2205487T3 (cg-RX-API-DMAC10.html)
FR (1) FR04C0013I2 (cg-RX-API-DMAC10.html)
GT (1) GT199800077A (cg-RX-API-DMAC10.html)
HN (1) HN1998000086A (cg-RX-API-DMAC10.html)
HR (1) HRP980314B1 (cg-RX-API-DMAC10.html)
HU (2) HU228005B1 (cg-RX-API-DMAC10.html)
ID (1) ID22992A (cg-RX-API-DMAC10.html)
IL (1) IL132809A0 (cg-RX-API-DMAC10.html)
IS (1) IS1998B (cg-RX-API-DMAC10.html)
LU (1) LU91076I9 (cg-RX-API-DMAC10.html)
MA (1) MA24564A1 (cg-RX-API-DMAC10.html)
ME (1) ME00876B (cg-RX-API-DMAC10.html)
MY (1) MY123354A (cg-RX-API-DMAC10.html)
NL (1) NL300150I2 (cg-RX-API-DMAC10.html)
NO (1) NO316911B1 (cg-RX-API-DMAC10.html)
NZ (2) NZ514871A (cg-RX-API-DMAC10.html)
OA (1) OA11224A (cg-RX-API-DMAC10.html)
PA (1) PA8452201A1 (cg-RX-API-DMAC10.html)
PE (1) PE79699A1 (cg-RX-API-DMAC10.html)
PL (1) PL191601B1 (cg-RX-API-DMAC10.html)
PT (1) PT988310E (cg-RX-API-DMAC10.html)
RS (1) RS49675B (cg-RX-API-DMAC10.html)
SI (1) SI0988310T1 (cg-RX-API-DMAC10.html)
SK (1) SK284171B6 (cg-RX-API-DMAC10.html)
TN (1) TNSN98082A1 (cg-RX-API-DMAC10.html)
TW (1) TW472060B (cg-RX-API-DMAC10.html)
UA (1) UA67744C2 (cg-RX-API-DMAC10.html)
UY (1) UY25040A1 (cg-RX-API-DMAC10.html)
WO (1) WO1998056802A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA985017B (cg-RX-API-DMAC10.html)

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ATE315042T1 (de) * 1999-08-24 2006-02-15 Abbott Lab 9a-azalide mit antibakterieller wirkung
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ATE429921T1 (de) * 2005-01-14 2009-05-15 Glaxosmithkline Zagreb 9a-carbamoyl- und thiocarbamoylazalide mit antimalariawirkung
US9453042B2 (en) * 2007-10-25 2016-09-27 Cempra Pharmaceuticals, Inc. Process for the preparation of macrolide antibacterial agents
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CN102724874B (zh) 2009-09-10 2018-06-01 森普拉制药公司 治疗疟疾、结核病和mac疾病的方法
PL2550286T3 (pl) 2010-03-22 2016-07-29 Cempra Pharmaceuticals Inc Krystaliczne postaci makrolidu i ich zastosowanie
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WO2012051126A2 (en) * 2010-10-10 2012-04-19 Synovo Gmbh Anti-inflammatory macrolides
CN102993250B (zh) * 2011-07-06 2016-02-10 洛阳惠中兽药有限公司 C-3取代的-9-脱氧-9a-氮杂-9a-高红霉素a衍生物
CN102260306B (zh) * 2011-07-22 2012-07-18 山东鲁抗舍里乐药业有限公司 一种制备泰拉霉素的方法
WO2013013834A1 (en) 2011-07-27 2013-01-31 Farma Grs, D.O.O. New crystalline forms of tulathromycin
SG11201405895UA (en) 2012-03-27 2014-10-30 Cempra Pharmaceuticals Inc Parenteral formulations for administering macrolide antibiotics
CN102786569B (zh) * 2012-09-07 2016-12-07 安徽中升药业有限公司 泰拉霉素中间体及其制备方法与泰拉霉素的制备方法
RU2015138796A (ru) 2013-03-14 2017-04-19 Семпра Фармасьютикалс, Инк. Способы и составы для лечения респираторных заболеваний
HK1218864A1 (zh) 2013-03-15 2017-03-17 森普拉制药公司 用於制备大环内酯抗菌剂的收敛方法
WO2015014907A1 (en) * 2013-07-31 2015-02-05 Farma Grs, D.O.O. Process for preparation of tulathromycin
CN103497227B (zh) * 2013-09-13 2015-09-30 青岛科技大学 一种泰拉菌素中间体的制备方法
CN104725446B (zh) * 2015-03-26 2017-10-27 宁夏泰瑞制药股份有限公司 一种从泰拉霉素粗品中分离泰拉霉素a和泰拉霉素b的方法
CN104861018A (zh) * 2015-06-17 2015-08-26 瑞普（天津）生物药业有限公司 一种泰拉菌素的制备方法
CN105646617A (zh) * 2016-01-21 2016-06-08 杭州海尔希畜牧科技有限公司 一种制备泰拉霉素的方法
FR3048612B1 (fr) * 2016-03-14 2020-10-02 Septeos Tulathromycine potentialisee
CN106046077B (zh) * 2016-08-04 2019-07-26 湖北美天生物科技股份有限公司 一种泰拉霉素a的合成方法
CN108003207B (zh) * 2017-12-19 2019-05-10 海门慧聚药业有限公司 制备泰拉霉素的方法
CN111087433B (zh) * 2018-10-23 2023-03-21 湖北美天生物科技股份有限公司 一种泰拉霉素中间体的制备方法

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UA70972C2 (uk) 1998-11-20 2004-11-15 Пфайзер Продактс Інк. 13-членні азаліди і їх застосування як антибіотиків

Also Published As

Publication number Publication date
HK1068893A1 (en) 2005-07-29
OA11224A (en) 2003-07-16
FR04C0013I2 (cg-RX-API-DMAC10.html) 2005-10-21
EP0988310B9 (en) 2006-03-08
UY25040A1 (es) 2000-09-29
CN1566129A (zh) 2005-01-19
HN1998000086A (es) 1999-03-08
NO316911B1 (no) 2004-06-21
AU7347598A (en) 1998-12-30
IL132809A0 (en) 2001-03-19
TW472060B (en) 2002-01-11
KR20010013632A (ko) 2001-02-26
CN101691390A (zh) 2010-04-07
US6777393B2 (en) 2004-08-17
ES2205487T3 (es) 2004-05-01
BRPI9810519B8 (pt) 2022-11-16
ID22992A (id) 1999-12-23
ME00876B (me) 2012-06-20
DE122004000018I2 (de) 2011-01-13
BRPI9810519B1 (pt) 2012-02-22
US20040180842A1 (en) 2004-09-16
HRP980314A2 (en) 1999-04-30
DE122004000018I1 (de) 2004-09-30
NO996106L (no) 2000-02-10
UA67744C2 (uk) 2004-07-15
PA8452201A1 (es) 2000-05-24
JP2000514098A (ja) 2000-10-24
NO996106D0 (no) 1999-12-10
ZA985017B (en) 1999-12-17
AP9801255A0 (en) 1998-06-30
CA2293823C (en) 2004-02-17
US6936592B2 (en) 2005-08-30
BRPI9810519A (pt) 2000-09-19
PL191601B1 (pl) 2006-06-30
MA24564A1 (fr) 1998-12-31
CO4950611A1 (es) 2000-09-01
NL300150I1 (nl) 2004-08-02
HK1028048A1 (en) 2001-02-02
FR04C0013I1 (cg-RX-API-DMAC10.html) 2004-06-11
EA199901015A1 (ru) 2000-06-26
EP0988310B1 (en) 2003-10-01
LU91076I9 (en) 2018-07-02
DE69818665T2 (de) 2004-04-29
DZ2514A1 (fr) 2003-02-01
IS5252A (is) 1999-11-16
GT199800077A (es) 1999-12-02
CN1259136A (zh) 2000-07-05
NZ514871A (en) 2003-08-29
HUS1200028I1 (hu) 2016-08-29
US6420536B1 (en) 2002-07-16
IS1998B (is) 2005-03-15
TNSN98082A1 (fr) 2005-03-15
NZ500660A (en) 2002-03-01
CN1243766C (zh) 2006-03-01
PT988310E (pt) 2003-12-31
CZ442199A3 (cs) 2000-07-12
SI0988310T1 (en) 2004-02-29
KR100396168B1 (ko) 2003-08-27
JP2002316933A (ja) 2002-10-31
HUP0002209A2 (hu) 2000-12-28
CA2293823A1 (en) 1998-12-17
CN1793155A (zh) 2006-06-28
AR013086A1 (es) 2000-12-13
RS49675B (sr) 2007-11-15
SK168399A3 (en) 2000-11-07
AU749816B2 (en) 2002-07-04
ATE251173T1 (de) 2003-10-15
WO1998056802A1 (en) 1998-12-17
HUP0002209A3 (en) 2003-05-28
CZ298556B6 (cs) 2007-11-07
LU91076I2 (fr) 2004-07-05
EP0988310A1 (en) 2000-03-29
DK0988310T3 (da) 2003-12-15
HRP980314B1 (en) 2004-04-30
YU58699A (cg-RX-API-DMAC10.html) 2002-08-12
MY123354A (en) 2006-05-31
JP3315704B2 (ja) 2002-08-19
HU228005B1 (en) 2012-08-28
SK284171B6 (sk) 2004-10-05
NL300150I2 (nl) 2004-09-01
HK1088014A1 (zh) 2006-10-27
BG64391B1 (bg) 2004-12-30
EA002441B1 (ru) 2002-04-25
CN1793155B (zh) 2010-05-12
US20040023896A1 (en) 2004-02-05
AP1231A (en) 2003-12-11
PL337505A1 (en) 2000-08-28
BG103945A (en) 2000-07-31
PE79699A1 (es) 1999-08-25
DE69818665D1 (de) 2003-11-06
US20020061858A1 (en) 2002-05-23
CN1172947C (zh) 2004-10-27

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