EE05675B1 - Meetod konformse haiguse diagnoosimiseks v?i tuvastamiseks, selleks vajalik katsemenetlus, reaktiivikomplekt ning seade - Google Patents

Meetod konformse haiguse diagnoosimiseks v?i tuvastamiseks, selleks vajalik katsemenetlus, reaktiivikomplekt ning seade

Info

Publication number
EE05675B1
EE05675B1 EEP200300005A EEP200300005A EE05675B1 EE 05675 B1 EE05675 B1 EE 05675B1 EE P200300005 A EEP200300005 A EE P200300005A EE P200300005 A EEP200300005 A EE P200300005A EE 05675 B1 EE05675 B1 EE 05675B1
Authority
EE
Estonia
Prior art keywords
diagnosis
detection
test procedure
reagent kit
required test
Prior art date
Application number
EEP200300005A
Other languages
English (en)
Inventor
Soto Claudio
Saborio Gabriella
Original Assignee
Applied Research Systems Ars Holding N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems Ars Holding N.V. filed Critical Applied Research Systems Ars Holding N.V.
Publication of EE200300005A publication Critical patent/EE200300005A/et
Publication of EE05675B1 publication Critical patent/EE05675B1/et

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2828—Prion diseases

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EEP200300005A 2000-07-07 2001-06-13 Meetod konformse haiguse diagnoosimiseks v?i tuvastamiseks, selleks vajalik katsemenetlus, reaktiivikomplekt ning seade EE05675B1 (et)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP00114650 2000-07-07
EP00127892 2000-12-20
EP01102732 2001-02-07
PCT/GB2001/002584 WO2002004954A2 (en) 2000-07-07 2001-06-13 Early diagnosis of conformational diseases

Publications (2)

Publication Number Publication Date
EE200300005A EE200300005A (et) 2004-08-16
EE05675B1 true EE05675B1 (et) 2013-08-15

Family

ID=27223071

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200300005A EE05675B1 (et) 2000-07-07 2001-06-13 Meetod konformse haiguse diagnoosimiseks v?i tuvastamiseks, selleks vajalik katsemenetlus, reaktiivikomplekt ning seade

Country Status (31)

Country Link
US (1) US7351526B2 (et)
EP (2) EP1299729B1 (et)
JP (1) JP4790966B2 (et)
KR (1) KR100764981B1 (et)
CN (1) CN1221807C (et)
AR (1) AR029583A1 (et)
AT (2) ATE426816T1 (et)
AU (2) AU6408901A (et)
BG (1) BG66272B1 (et)
BR (1) BRPI0112262B8 (et)
CA (1) CA2413078C (et)
CY (1) CY1109106T1 (et)
CZ (1) CZ304365B6 (et)
DE (2) DE60138146D1 (et)
DK (2) DK1712920T3 (et)
EA (1) EA007391B1 (et)
EE (1) EE05675B1 (et)
ES (2) ES2264691T3 (et)
HK (1) HK1058065A1 (et)
HR (1) HRP20030033B1 (et)
HU (1) HU228813B1 (et)
IL (2) IL153824A0 (et)
MX (1) MXPA03000226A (et)
NO (1) NO331624B1 (et)
NZ (1) NZ523213A (et)
PL (1) PL211154B1 (et)
PT (2) PT1299729E (et)
RS (1) RS51523B (et)
SI (2) SI1299729T1 (et)
SK (1) SK287768B6 (et)
WO (1) WO2002004954A2 (et)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1373904A1 (de) * 2001-03-13 2004-01-02 Eigen, Manfred, Prof. Dr. Verfahren zur verstärkung der bildung von aggregaten aus proteinuntereinheiten
US20050026165A1 (en) * 2001-05-31 2005-02-03 Cindy Orser Detection of conformationally altered proteins and prions
EP1395833B1 (en) * 2001-05-31 2013-02-27 Adlyfe, Inc. Misfolded protein sensor method
ES2401645T3 (es) * 2003-06-19 2013-04-23 Merck Serono Sa Uso de agentes moduladores de la conversión de priones
DE10328125A1 (de) * 2003-06-23 2005-01-13 Roche Diagnostics Gmbh Nachweis von Protease-resistentem Prion-Protein nach spontaner Transformationsreaktion
DE10328830A1 (de) * 2003-06-26 2005-01-20 Roche Diagnostics Gmbh Nachweis von Protease-resistentem Prion-Protein nach asymmetrischer Interaktion
US20070054322A1 (en) * 2003-07-31 2007-03-08 Hadasit Medical Research Services & Development Lt Methods and kits for the detection of prion diseases
JP4709149B2 (ja) 2003-08-13 2011-06-22 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド プリオン特異的ペプチド試薬
US20060057671A1 (en) * 2004-09-10 2006-03-16 Orser Cindy S Immobilized probes and methods of detecting conformationally altered prion proteins
JP4568840B2 (ja) * 2004-12-28 2010-10-27 国立大学法人金沢大学 アルツハイマー病の検査方法
ATE528649T1 (de) * 2005-02-15 2011-10-15 Adlyfe Inc Verfahren zum nachweis falsch gefalteter proteine und prionen
CN101218510A (zh) * 2005-04-20 2008-07-09 得克萨斯系统大学评议会 通过自动化的蛋白质错折叠循环扩增超灵敏检测朊病毒
EP1731911A1 (fr) * 2005-06-07 2006-12-13 Institut National De La Sante Et De La Recherche Medicale (Inserm) Procédé utile pour la détection d'encéphalopathies
DE102005031429A1 (de) * 2005-07-04 2007-01-11 Heinrich-Heine-Universität Düsseldorf Verfahren zur selektiven Bestimmung pathologischer Proteinablagerungen
NZ566020A (en) 2005-09-09 2012-08-31 Novartis Ag Prion-specific peptoid reagents
US20070281367A1 (en) 2006-05-03 2007-12-06 Applera Corporation Methods, Compositions, and Kits for Quantitating Antibodies
WO2008013859A2 (en) 2006-07-28 2008-01-31 Adlyfe, Inc. Peptide probes for diagnostics and therapeutics
WO2008030973A2 (en) * 2006-09-06 2008-03-13 The Board Of Regents Of The University Of Texas System Methods and compositions for the detection of protein folding disorders
EP2179293B1 (en) * 2007-07-20 2014-09-03 The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services Detection of infectious prion protein by seeded conversion of recombinant prion protein
FR2929290B1 (fr) * 2008-03-27 2010-05-07 Lfb Biotechnologies Methode de detection et/ou de titrage in vitro d'un agent transmissible non conventionnel
CA2725100C (en) 2008-05-28 2014-02-18 Incorporated Administrative Agency National Agriculture And Food Research Organization Method for efficiently amplifying abnormal prion protein derived from bse
EP2280028B1 (en) 2008-05-28 2013-03-27 Incorporated Administrative Agency National Agriculture and Food Research Organization Method for efficiently amplifying abnormal prion protein derived from sheep scrapie
ITMI20081052A1 (it) * 2008-06-10 2009-12-11 Univ Milano Bicocca Liposomi in grado di legare efficacemente il peptide beta-amiloide
FR2935711A1 (fr) * 2008-09-05 2010-03-12 Lfb Biotechnologies Clone cellulaire stable exprimant un prion
CA2779846A1 (en) * 2009-11-04 2011-05-12 Novartis Ag Positively charged species as binding reagents in the separation of protein aggregates from monomers
US10215763B2 (en) * 2010-05-18 2019-02-26 Board Of Regents Of The University Of Texas System Methods for estimating prion concentration in fluids and tissue by quantitative PMCA
US9910049B2 (en) 2014-09-11 2018-03-06 Amprion, Inc. Detection of misfolded amyloid beta protein
US10989718B2 (en) 2014-09-11 2021-04-27 Amprion, Inc. Detection of misfolded alpha synuclein protein
IT1405762B1 (it) 2010-11-25 2014-01-24 Icgeb Proteine ricombinanti con attivita' di inattivazione selettiva di proteine bersaglio
CN103460049B (zh) * 2011-01-18 2016-08-17 美国政府(由卫生和人类服务部的部长所代表) 扩增和检测朊病毒的方法
FR2973114A1 (fr) 2011-03-21 2012-09-28 Ets Francais Du Sang Nanobilles recouvertes de plasminogene comme support direct d'amplification cyclique de la proteine prion prpsc
WO2013056841A1 (en) 2011-10-19 2013-04-25 Inra (Institut National De La Recherche Agronomique) A method for diagnosing tse
WO2015160007A1 (ko) * 2014-04-17 2015-10-22 한림대학교 산학협력단 극미량 병원성 프리온 단백질 검출방법 및 장치
EP3191599B1 (en) 2014-09-11 2023-08-02 Board Of Regents Of the University Of Texas System Detection of misfolded proteins
US10359434B2 (en) 2014-10-22 2019-07-23 Colorado State University Research Foundation In vitro detection of prions in blood
WO2016149537A1 (en) 2015-03-17 2016-09-22 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Bank vole prion protein as a broad-spectrum substrate for rt-quic-based detection and discrimination of prion strains
KR20200007945A (ko) 2017-05-16 2020-01-22 암프리온, 인코퍼레이티드 미스폴딩된 타우 단백질의 검출
US20190353669A1 (en) * 2018-05-16 2019-11-21 Amprion, Inc. Detection of Brain Injury or Neurological Disease using Tau Protein
US11598783B1 (en) 2019-10-23 2023-03-07 Colorado State University Research Foundation In vitro detection of prions
WO2021198098A1 (en) 2020-04-03 2021-10-07 Universität Zürich Improved method of detecting biomarkers in a biological sample

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5262332A (en) 1989-04-05 1993-11-16 Brigham And Women's Hospital Diagnostic method for Alzheimer's disease: examination of non-neural tissue
US5616871A (en) * 1995-09-28 1997-04-01 Drummond Scientific Company Pipet gun assembly
US5750361A (en) * 1995-11-02 1998-05-12 The Regents Of The University Of California Formation and use of prion protein (PRP) complexes
WO1998016834A1 (en) 1996-10-15 1998-04-23 Imperial College Of Science, Technology And Medicine Diagnosis of spongiform encephalopathy
CA2376914A1 (en) 1999-06-29 2001-01-04 Mcgill University Prion protein binding proteins and uses thereof
WO2001046714A1 (en) * 1999-12-10 2001-06-28 Misonix Incorporated Ultrasonic horn assembly
CN101218510A (zh) * 2005-04-20 2008-07-09 得克萨斯系统大学评议会 通过自动化的蛋白质错折叠循环扩增超灵敏检测朊病毒

Also Published As

Publication number Publication date
HK1058065A1 (en) 2004-04-30
EP1299729A2 (en) 2003-04-09
SI1712920T1 (sl) 2009-10-31
WO2002004954A3 (en) 2002-10-24
EP1712920B1 (en) 2009-03-25
CZ200336A3 (cs) 2003-06-18
SI1299729T1 (sl) 2006-10-31
DE60138146D1 (de) 2009-05-07
HU228813B1 (en) 2013-05-28
EP1712920A1 (en) 2006-10-18
PL360397A1 (en) 2004-09-06
HRP20030033A2 (en) 2004-02-29
US7351526B2 (en) 2008-04-01
ES2264691T3 (es) 2007-01-16
CY1109106T1 (el) 2014-07-02
AU6408901A (en) 2002-01-21
PL211154B1 (pl) 2012-04-30
EP1299729B1 (en) 2006-08-02
BRPI0112262B1 (pt) 2016-08-09
HRP20030033B1 (en) 2008-04-30
JP4790966B2 (ja) 2011-10-12
DK1299729T3 (da) 2006-12-04
EA200300126A1 (ru) 2003-06-26
CN1221807C (zh) 2005-10-05
IL153824A0 (en) 2003-07-31
SK287768B6 (sk) 2011-09-05
ATE426816T1 (de) 2009-04-15
BRPI0112262B8 (pt) 2021-07-27
ATE335204T1 (de) 2006-08-15
KR100764981B1 (ko) 2007-10-09
IL153824A (en) 2010-02-17
AR029583A1 (es) 2003-07-02
DE60121958T2 (de) 2007-02-01
RS51523B (sr) 2011-06-30
DE60121958D1 (de) 2006-09-14
EE200300005A (et) 2004-08-16
BR0112262A (pt) 2003-05-20
WO2002004954A2 (en) 2002-01-17
ES2322660T3 (es) 2009-06-24
SK18582002A3 (sk) 2003-05-02
NZ523213A (en) 2005-01-28
CZ304365B6 (cs) 2014-04-02
PT1299729E (pt) 2006-10-31
NO20030059L (no) 2003-03-07
JP2004503748A (ja) 2004-02-05
YU101202A (sh) 2006-01-16
NO331624B1 (no) 2012-02-06
AU2001264089B2 (en) 2006-03-30
CA2413078A1 (en) 2002-01-17
BG107498A (bg) 2003-11-28
DK1712920T3 (da) 2009-05-11
US20050064505A1 (en) 2005-03-24
MXPA03000226A (es) 2004-05-21
HUP0301020A3 (en) 2010-03-29
PT1712920E (pt) 2009-04-09
KR20030036257A (ko) 2003-05-09
EA007391B1 (ru) 2006-10-27
HUP0301020A2 (hu) 2003-07-28
NO20030059D0 (no) 2003-01-06
CA2413078C (en) 2010-08-03
BG66272B1 (bg) 2012-11-30
CN1449497A (zh) 2003-10-15

Similar Documents

Publication Publication Date Title
EE05675B1 (et) Meetod konformse haiguse diagnoosimiseks v?i tuvastamiseks, selleks vajalik katsemenetlus, reaktiivikomplekt ning seade
ITRM20030386A0 (it) Metodo e test diagnostici basati sull'analisi citofluorimetrica dei linfociti t antigene-specifici.
FI20011877A (fi) Menetelmä ja bioanturi analyysiä varten
EE200300128A (et) Meetod allergeeniga seostuva immunoglobuliini detekteerimiseks proovis, patsiendi allergiate in vitro diagnoosimeetod, mikromaatrikskiip ja komplekt
DE602004018575D1 (de) Chirurgisches Ultraschallsystem und Probe
ATE514945T1 (de) Diagnoseverfahren für maul- und klauenseuche und diagnostischer kit
DE60043049D1 (de) Bluttestvorrichtung
DE60141171D1 (de) Klinische intelligente diagnostische vorrichtungen und verfahren
DE60223635D1 (de) Reagenzien, Verfahren und Vorrichtungen zum Nachweis von Analyten
DE60030756D1 (de) Körperflüssigkeitsmessinstrument und körperflüssigkeitsprobeentnahmegerät
DK1371984T3 (da) Chromatografisk assay-anordning og fremgangsmåde til detektion af tilstedeværelsen af en analyt i en helblodpröve
FI990559A0 (fi) Näytteenkäsittelymenetelmä ja diagnostinen mittauslaite
DE50202018D1 (de) Intrakorporale sonde zur analyse oder diagnose und/oder therapie
DE60133982D1 (de) Biosensor und verfahren zum analysieren von blutkomponenten
ZA200700525B (en) Enriched antibody for detecting mycobacterial infection, methods of use and diagnostic test employing same
FR2810444B1 (fr) Dispositif de collimation, appareil de radiologie, kit de test et procede de test d'un appareil de radiologie
AU2003289853A8 (en) Methods, device and instrument for detection of analytes
NO20012150L (no) Kvantitativt kjemisk analysemetode, anordning/innretning, samt anvendelse av nevnte metode og analysesett
DE19983966T1 (de) Immunodiagnostisches Testverfahren für eine Tierkrankheit
BR9917198B1 (pt) dispositivo de teste para detecção ou enumeração de microorganismos, e, processo para utilizar um dispositivo de teste.
DE60037595D1 (de) Vorrichtung zur zerstörungsfreien prüfung
WO2006055422A3 (en) Sampling device and methods
GB2361770B (en) Measuring and evaluating device for the analysis of gases
DE60118533D1 (de) Labormikrochipvorrichtung und Verfahren für chemische Analyse
FR2816058B1 (fr) Methode et dispositif de determination de la concentration de dioxines

Legal Events

Date Code Title Description
GB1A Change in the ownership or in the address of the owner
HC1A Change of owner name