EE200300005A - Meetod konformse haiguse diagnoosimiseks või tuvastamiseks, selleks vajalik katsemenetlus, reaktiivikomplekt ning seade - Google Patents

Meetod konformse haiguse diagnoosimiseks või tuvastamiseks, selleks vajalik katsemenetlus, reaktiivikomplekt ning seade

Info

Publication number
EE200300005A
EE200300005A EEP200300005A EEP200300005A EE200300005A EE 200300005 A EE200300005 A EE 200300005A EE P200300005 A EEP200300005 A EE P200300005A EE P200300005 A EEP200300005 A EE P200300005A EE 200300005 A EE200300005 A EE 200300005A
Authority
EE
Estonia
Prior art keywords
diagnosis
detection
test procedure
reagent kit
required test
Prior art date
Application number
EEP200300005A
Other languages
English (en)
Inventor
Soto Claudio
Saborio Gabriella
Original Assignee
Applied Research Systems Ars Holding N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems Ars Holding N.V. filed Critical Applied Research Systems Ars Holding N.V.
Publication of EE200300005A publication Critical patent/EE200300005A/et
Publication of EE05675B1 publication Critical patent/EE05675B1/et

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2828—Prion diseases
EEP200300005A 2000-07-07 2001-06-13 Meetod konformse haiguse diagnoosimiseks v?i tuvastamiseks, selleks vajalik katsemenetlus, reaktiivikomplekt ning seade EE05675B1 (et)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP00114650 2000-07-07
EP00127892 2000-12-20
EP01102732 2001-02-07
PCT/GB2001/002584 WO2002004954A2 (en) 2000-07-07 2001-06-13 Early diagnosis of conformational diseases

Publications (2)

Publication Number Publication Date
EE200300005A true EE200300005A (et) 2004-08-16
EE05675B1 EE05675B1 (et) 2013-08-15

Family

ID=27223071

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200300005A EE05675B1 (et) 2000-07-07 2001-06-13 Meetod konformse haiguse diagnoosimiseks v?i tuvastamiseks, selleks vajalik katsemenetlus, reaktiivikomplekt ning seade

Country Status (31)

Country Link
US (1) US7351526B2 (et)
EP (2) EP1712920B1 (et)
JP (1) JP4790966B2 (et)
KR (1) KR100764981B1 (et)
CN (1) CN1221807C (et)
AR (1) AR029583A1 (et)
AT (2) ATE426816T1 (et)
AU (2) AU6408901A (et)
BG (1) BG66272B1 (et)
BR (1) BRPI0112262B8 (et)
CA (1) CA2413078C (et)
CY (1) CY1109106T1 (et)
CZ (1) CZ304365B6 (et)
DE (2) DE60121958T2 (et)
DK (2) DK1712920T3 (et)
EA (1) EA007391B1 (et)
EE (1) EE05675B1 (et)
ES (2) ES2264691T3 (et)
HK (1) HK1058065A1 (et)
HR (1) HRP20030033B1 (et)
HU (1) HU228813B1 (et)
IL (2) IL153824A0 (et)
MX (1) MXPA03000226A (et)
NO (1) NO331624B1 (et)
NZ (1) NZ523213A (et)
PL (1) PL211154B1 (et)
PT (2) PT1299729E (et)
RS (1) RS51523B (et)
SI (2) SI1299729T1 (et)
SK (1) SK287768B6 (et)
WO (1) WO2002004954A2 (et)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002073210A1 (de) * 2001-03-13 2002-09-19 Manfred Eigen Verfahren zur verstärkung der bildung von aggregaten aus proteinuntereinheiten
US20050026165A1 (en) 2001-05-31 2005-02-03 Cindy Orser Detection of conformationally altered proteins and prions
CA2448981C (en) 2001-05-31 2014-03-18 Arete Associates Misfolded protein sensor method
EP1636592B1 (en) * 2003-06-19 2012-12-19 Merck Serono SA Use of prion conversion modulating agents
DE10328125A1 (de) * 2003-06-23 2005-01-13 Roche Diagnostics Gmbh Nachweis von Protease-resistentem Prion-Protein nach spontaner Transformationsreaktion
DE10328830A1 (de) * 2003-06-26 2005-01-20 Roche Diagnostics Gmbh Nachweis von Protease-resistentem Prion-Protein nach asymmetrischer Interaktion
WO2005010533A2 (en) * 2003-07-31 2005-02-03 Hadasit Medical Research Services & Development Ltd. Methods and kits for the detection of prion diseases
NZ580256A (en) 2003-08-13 2011-07-29 Novartis Vaccines & Diagnostic Prion-specific peptide reagents comprising the sequence KKRPKPGG
US20060057671A1 (en) * 2004-09-10 2006-03-16 Orser Cindy S Immobilized probes and methods of detecting conformationally altered prion proteins
JP4568840B2 (ja) * 2004-12-28 2010-10-27 国立大学法人金沢大学 アルツハイマー病の検査方法
US8372593B2 (en) * 2005-02-15 2013-02-12 Adlyfe, Inc. Method for detecting misfolded proteins and prions
WO2006113915A2 (en) * 2005-04-20 2006-10-26 Board Of Regents, The University Of Texas System Ultrasensitive detection of prions by automated protein misfolding cyclic amplification
EP1731911A1 (fr) * 2005-06-07 2006-12-13 Institut National De La Sante Et De La Recherche Medicale (Inserm) Procédé utile pour la détection d'encéphalopathies
DE102005031429A1 (de) * 2005-07-04 2007-01-11 Heinrich-Heine-Universität Düsseldorf Verfahren zur selektiven Bestimmung pathologischer Proteinablagerungen
EP1931695B1 (en) 2005-09-09 2013-04-10 Novartis AG Prion-specific peptoid reagents
US20070281367A1 (en) 2006-05-03 2007-12-06 Applera Corporation Methods, Compositions, and Kits for Quantitating Antibodies
WO2008013859A2 (en) 2006-07-28 2008-01-31 Adlyfe, Inc. Peptide probes for diagnostics and therapeutics
EP2074222A4 (en) * 2006-09-06 2010-03-03 Univ Texas METHODS AND COMPOSITIONS FOR DETECTION OF PROTEIN FOLDING DISORDERS
WO2009015091A1 (en) * 2007-07-20 2009-01-29 The Government of the United States of America as represented by the Secretary of the Detection of infectious prion protein by seeded conversion of recombinant prion protein
FR2929290B1 (fr) * 2008-03-27 2010-05-07 Lfb Biotechnologies Methode de detection et/ou de titrage in vitro d'un agent transmissible non conventionnel
US20110124843A1 (en) 2008-05-28 2011-05-26 Incorporated Administrative Agency National Agriculture And Food Research Organization Method for efficiently amplifying abnormal prion protein derived from bse
JP5209711B2 (ja) 2008-05-28 2013-06-12 独立行政法人農業・食品産業技術総合研究機構 羊スクレイピー由来異常プリオン蛋白質の効率的増幅方法
ITMI20081052A1 (it) * 2008-06-10 2009-12-11 Univ Milano Bicocca Liposomi in grado di legare efficacemente il peptide beta-amiloide
FR2935711A1 (fr) * 2008-09-05 2010-03-12 Lfb Biotechnologies Clone cellulaire stable exprimant un prion
EP2496947A1 (en) * 2009-11-04 2012-09-12 Novartis AG Positively charged species as binding reagents in the separation of protein aggregates from monomers
US10215763B2 (en) * 2010-05-18 2019-02-26 Board Of Regents Of The University Of Texas System Methods for estimating prion concentration in fluids and tissue by quantitative PMCA
IT1405762B1 (it) 2010-11-25 2014-01-24 Icgeb Proteine ricombinanti con attivita' di inattivazione selettiva di proteine bersaglio
AU2012207454B2 (en) * 2011-01-18 2016-11-17 Prionics Ag Methods for amplification and detection of prions
FR2973114A1 (fr) 2011-03-21 2012-09-28 Ets Francais Du Sang Nanobilles recouvertes de plasminogene comme support direct d'amplification cyclique de la proteine prion prpsc
WO2013056841A1 (en) 2011-10-19 2013-04-25 Inra (Institut National De La Recherche Agronomique) A method for diagnosing tse
WO2015160007A1 (ko) * 2014-04-17 2015-10-22 한림대학교 산학협력단 극미량 병원성 프리온 단백질 검출방법 및 장치
WO2016040903A1 (en) 2014-09-11 2016-03-17 Board Of Regents Of The University Of Texas System Detection of misfolded amyloid beta protein
KR102448128B1 (ko) 2014-09-11 2022-09-27 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 미스폴딩된 단백질의 검출
WO2016040905A1 (en) 2014-09-11 2016-03-17 Board Of Regents Of The University Of Texas System Detection of misfolded alpha synuclein protein
US10359434B2 (en) 2014-10-22 2019-07-23 Colorado State University Research Foundation In vitro detection of prions in blood
WO2016149537A1 (en) 2015-03-17 2016-09-22 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Bank vole prion protein as a broad-spectrum substrate for rt-quic-based detection and discrimination of prion strains
BR112019024138A2 (pt) 2017-05-16 2020-06-02 Amprion, Inc. Método para determinar uma presença ou ausência em uma amostra de um primeiro agregado de proteínas mal enoveladas
US20190353669A1 (en) * 2018-05-16 2019-11-21 Amprion, Inc. Detection of Brain Injury or Neurological Disease using Tau Protein
US11598783B1 (en) 2019-10-23 2023-03-07 Colorado State University Research Foundation In vitro detection of prions
WO2021198098A1 (en) 2020-04-03 2021-10-07 Universität Zürich Improved method of detecting biomarkers in a biological sample

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5262332A (en) * 1989-04-05 1993-11-16 Brigham And Women's Hospital Diagnostic method for Alzheimer's disease: examination of non-neural tissue
US5616871A (en) * 1995-09-28 1997-04-01 Drummond Scientific Company Pipet gun assembly
US5750361A (en) * 1995-11-02 1998-05-12 The Regents Of The University Of California Formation and use of prion protein (PRP) complexes
EP0934531B1 (en) 1996-10-15 2004-08-04 D-Gen Limited Diagnosis of spongiform encephalopathy
CA2376914A1 (en) * 1999-06-29 2001-01-04 Mcgill University Prion protein binding proteins and uses thereof
WO2001046714A1 (en) * 1999-12-10 2001-06-28 Misonix Incorporated Ultrasonic horn assembly
WO2006113915A2 (en) * 2005-04-20 2006-10-26 Board Of Regents, The University Of Texas System Ultrasensitive detection of prions by automated protein misfolding cyclic amplification

Also Published As

Publication number Publication date
US7351526B2 (en) 2008-04-01
SI1712920T1 (sl) 2009-10-31
NZ523213A (en) 2005-01-28
ATE426816T1 (de) 2009-04-15
EA200300126A1 (ru) 2003-06-26
DK1712920T3 (da) 2009-05-11
CZ200336A3 (cs) 2003-06-18
CA2413078A1 (en) 2002-01-17
ATE335204T1 (de) 2006-08-15
AU2001264089B2 (en) 2006-03-30
EE05675B1 (et) 2013-08-15
CN1449497A (zh) 2003-10-15
SK18582002A3 (sk) 2003-05-02
CN1221807C (zh) 2005-10-05
BG66272B1 (bg) 2012-11-30
BRPI0112262B8 (pt) 2021-07-27
CY1109106T1 (el) 2014-07-02
SK287768B6 (sk) 2011-09-05
DE60138146D1 (de) 2009-05-07
HRP20030033B1 (en) 2008-04-30
MXPA03000226A (es) 2004-05-21
HUP0301020A3 (en) 2010-03-29
EP1712920A1 (en) 2006-10-18
IL153824A (en) 2010-02-17
KR100764981B1 (ko) 2007-10-09
CZ304365B6 (cs) 2014-04-02
HRP20030033A2 (en) 2004-02-29
PL360397A1 (en) 2004-09-06
ES2264691T3 (es) 2007-01-16
RS51523B (sr) 2011-06-30
SI1299729T1 (sl) 2006-10-31
KR20030036257A (ko) 2003-05-09
NO20030059D0 (no) 2003-01-06
NO331624B1 (no) 2012-02-06
BR0112262A (pt) 2003-05-20
ES2322660T3 (es) 2009-06-24
CA2413078C (en) 2010-08-03
JP2004503748A (ja) 2004-02-05
DE60121958T2 (de) 2007-02-01
JP4790966B2 (ja) 2011-10-12
YU101202A (sh) 2006-01-16
EP1299729B1 (en) 2006-08-02
EP1712920B1 (en) 2009-03-25
BG107498A (bg) 2003-11-28
PL211154B1 (pl) 2012-04-30
EP1299729A2 (en) 2003-04-09
BRPI0112262B1 (pt) 2016-08-09
WO2002004954A2 (en) 2002-01-17
HU228813B1 (en) 2013-05-28
AU6408901A (en) 2002-01-21
IL153824A0 (en) 2003-07-31
DK1299729T3 (da) 2006-12-04
HK1058065A1 (en) 2004-04-30
PT1712920E (pt) 2009-04-09
US20050064505A1 (en) 2005-03-24
DE60121958D1 (de) 2006-09-14
PT1299729E (pt) 2006-10-31
EA007391B1 (ru) 2006-10-27
HUP0301020A2 (hu) 2003-07-28
AR029583A1 (es) 2003-07-02
NO20030059L (no) 2003-03-07
WO2002004954A3 (en) 2002-10-24

Similar Documents

Publication Publication Date Title
EE200300005A (et) Meetod konformse haiguse diagnoosimiseks või tuvastamiseks, selleks vajalik katsemenetlus, reaktiivikomplekt ning seade
FI20011877A (fi) Menetelmä ja bioanturi analyysiä varten
DE60107322D1 (de) Apparat und Methode zur Normalisung biometrischer Bewertungsmasse
AU2002346484A1 (en) Method and apparatus for improving the accuracy of alternative site analyte concentration measurements
BR0318312A (pt) método de diagnóstico de doença dos pés e boca por infecção virótica e kit de diagnóstico de doença dos pés e boca por infecção virótica
FI990559A0 (fi) Näytteenkäsittelymenetelmä ja diagnostinen mittauslaite
NO20016364D0 (no) Fremgangsmåte og anordning for noninvasiv blodanalysemåling
ATE336942T1 (de) Vorrichtung zur entnahme biologischer flüssigkeiten und analytenmessung
PL355270A1 (en) Method of determining concentration of analyte in a sample as well as a measuring instrument and its associated apparatus for determining concentration of analyte in a sample
ITRM20030386A0 (it) Metodo e test diagnostici basati sull'analisi citofluorimetrica dei linfociti t antigene-specifici.
DE60133982D1 (de) Biosensor und verfahren zum analysieren von blutkomponenten
EP1291643A4 (en) METHOD AND APPARATUS FOR MEASURING FLUORESCENCE, AND APPARATUS FOR EVALUATING SAMPLE USING MEASURING APPARATUS
EP1450668A4 (en) METHOD AND APPARATUS FOR DETECTING NEUROMUSCULAR DISEASES BY ANALYSIS OF DISEASE-SPECIFIC EVOCATED NEUROMUSCULAR ANSWER
ZA200700525B (en) Enriched antibody for detecting mycobacterial infection, methods of use and diagnostic test employing same
FR2810444B1 (fr) Dispositif de collimation, appareil de radiologie, kit de test et procede de test d'un appareil de radiologie
AU2003289853A8 (en) Methods, device and instrument for detection of analytes
DE19983966T1 (de) Immunodiagnostisches Testverfahren für eine Tierkrankheit
DE60037595D1 (de) Vorrichtung zur zerstörungsfreien prüfung
FI20015015A (fi) Menetelmä ja laitteisto analyyttien kvalitatiiviseksi ja kvantitatiiviseksi osoittamiseksi
WO2006055422A3 (en) Sampling device and methods
DE60118533D1 (de) Labormikrochipvorrichtung und Verfahren für chemische Analyse
DE50211292D1 (de) Untersuchungsvorrichtung und verfahren zum untersuchen chemischer und/oder biologischer proben
ITMI20001002A0 (it) Metodo e apparecchiatura per la diagnosi precoce di tumori vescicali su campioni di urina
EA200100544A1 (ru) Способ экспресс-диагностики физиологического состояния биологического объекта и устройство для его осуществления
NO20030259D0 (no) Deteksjonsmetode for endometrial status ved anvendelse av tester brukt på endometrial menstruasjonsvev

Legal Events

Date Code Title Description
GB1A Change in the ownership or in the address of the owner
HC1A Change of owner name