ECSP17029371A - Dihidropirrolopiridinas inhibidoras de ror-gamma - Google Patents

Dihidropirrolopiridinas inhibidoras de ror-gamma

Info

Publication number
ECSP17029371A
ECSP17029371A ECIEPI201729371A ECPI201729371A ECSP17029371A EC SP17029371 A ECSP17029371 A EC SP17029371A EC IEPI201729371 A ECIEPI201729371 A EC IEPI201729371A EC PI201729371 A ECPI201729371 A EC PI201729371A EC SP17029371 A ECSP17029371 A EC SP17029371A
Authority
EC
Ecuador
Prior art keywords
dihydropyrrolopyridines
ror
gamma
inhibiting
attached
Prior art date
Application number
ECIEPI201729371A
Other languages
English (en)
Inventor
Chengguo Dong
Colin M Tice
Linghang Zhuang
Stephen D Lotesta
Yi Fan
Jing Yuan
Andrew Marcus
Suresh Singh
Lawrence Wayne Dillard
David A Claremon
Lanqi Jia
Wei Zhao
Yajun Zheng
Original Assignee
Vitae Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vitae Pharmaceuticals Inc filed Critical Vitae Pharmaceuticals Inc
Publication of ECSP17029371A publication Critical patent/ECSP17029371A/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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Abstract

se adjunta resumen
ECIEPI201729371A 2014-10-14 2017-05-12 Dihidropirrolopiridinas inhibidoras de ror-gamma ECSP17029371A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462063912P 2014-10-14 2014-10-14
US201462074406P 2014-11-03 2014-11-03

Publications (1)

Publication Number Publication Date
ECSP17029371A true ECSP17029371A (es) 2019-02-28

Family

ID=54352515

Family Applications (1)

Application Number Title Priority Date Filing Date
ECIEPI201729371A ECSP17029371A (es) 2014-10-14 2017-05-12 Dihidropirrolopiridinas inhibidoras de ror-gamma

Country Status (28)

Country Link
US (3) US9796710B2 (es)
EP (1) EP3207043B3 (es)
JP (1) JP6564029B2 (es)
KR (1) KR20170066628A (es)
CN (1) CN107074852B (es)
AU (1) AU2015333610B2 (es)
BR (1) BR112017007460A2 (es)
CA (1) CA2963140A1 (es)
CL (1) CL2017000902A1 (es)
CO (1) CO2017004525A2 (es)
CY (1) CY1121413T1 (es)
DK (1) DK3207043T6 (es)
EA (1) EA031967B1 (es)
EC (1) ECSP17029371A (es)
ES (1) ES2715458T7 (es)
HU (1) HUE042335T2 (es)
IL (1) IL251584B (es)
MX (1) MX371304B (es)
MY (1) MY182454A (es)
PH (1) PH12017500583A1 (es)
PL (1) PL3207043T6 (es)
PT (1) PT3207043T (es)
SG (1) SG11201702362SA (es)
SI (1) SI3207043T1 (es)
TW (1) TWI675032B (es)
UA (1) UA118989C2 (es)
WO (1) WO2016061160A1 (es)
ZA (1) ZA201702237B (es)

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MA41898A (fr) 2015-04-10 2018-02-13 Hoffmann La Roche Dérivés de quinazolinone bicyclique
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RU2746481C1 (ru) 2015-09-04 2021-04-14 Ф. Хоффманн-Ля Рош Аг Феноксиметильные производные
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TW202220968A (zh) * 2016-01-29 2022-06-01 美商維它藥物有限責任公司 ＲＯＲ－γ調節劑
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JP7090099B2 (ja) 2017-03-16 2022-06-23 エフ．ホフマン－ラ ロシュ アーゲー Ａｔｘインヒビターとしての新規二環式化合物
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JP2020142989A (ja) * 2017-06-21 2020-09-10 Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 イミダゾール誘導体及びそれを含有する医薬
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