US8568766B2
(en)
*
|
2000-08-24 |
2013-10-29 |
Gattadahalli M. Anantharamaiah |
Peptides and peptide mimetics to treat pathologies associated with eye disease
|
US7199102B2
(en)
*
|
2000-08-24 |
2007-04-03 |
The Regents Of The University Of California |
Orally administered peptides synergize statin activity
|
US7723303B2
(en)
*
|
2000-08-24 |
2010-05-25 |
The Regents Of The University Of California |
Peptides and peptide mimetics to treat pathologies characterized by an inflammatory response
|
US20060148725A1
(en)
*
|
2001-12-21 |
2006-07-06 |
The Miriam Hospital |
Selective 11beta HSD inhibitors and methods of use thereof
|
US20030148987A1
(en)
*
|
2001-12-21 |
2003-08-07 |
Morris David J. |
Selective 11beta-HSD inhibitors and methods of use thereof
|
NZ534757A
(en)
|
2002-03-12 |
2006-07-28 |
Merck & Co Inc |
Substituted amides
|
AR040241A1
(es)
*
|
2002-06-10 |
2005-03-23 |
Merck & Co Inc |
Inhibidores de la 11-beta-hidroxiesteroide deshidrogrenasa 1 para el tratamiento de la diabetes obesidad y dislipidemia
|
JO2397B1
(en)
*
|
2002-12-20 |
2007-06-17 |
ميرك شارب اند دوم كوربوريشن |
Terazol derivatives as beta-hydroxy steroid dihydrogenase-1 inhibitors
|
US8293751B2
(en)
|
2003-01-14 |
2012-10-23 |
Arena Pharmaceuticals, Inc. |
1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia
|
MY142651A
(en)
*
|
2003-03-18 |
2010-12-15 |
Merck Sharp & Dohme |
Biaryl substituted triazoles as sodium channel blockers
|
US20060183897A1
(en)
*
|
2003-03-18 |
2006-08-17 |
Chakravarty Prasun K |
Biaryl substituted triazoles as sodium channel blockers
|
WO2004097002A2
(en)
*
|
2003-04-29 |
2004-11-11 |
The Miriam Hospital |
SELECTIVE TESTICULAR 11β-HSD INHIBITORS AND METHODS OF USE THEREOF
|
CN1795181A
(zh)
*
|
2003-05-29 |
2006-06-28 |
麦克公司 |
用作11β-羟基类固醇脱氢酶-1抑制剂的三唑衍生物
|
EP1644375A2
(en)
|
2003-07-14 |
2006-04-12 |
Arena Pharmaceuticals, Inc. |
Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto
|
JP2007533625A
(ja)
|
2003-09-22 |
2007-11-22 |
バイオネットワークス ゲゼルシャフト ミット ベシュレンクテル ハフツング |
炎症性及び/又は免疫媒介性の骨量減少の予防及び治療
|
US8415354B2
(en)
|
2004-04-29 |
2013-04-09 |
Abbott Laboratories |
Methods of use of inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
|
US20100222316A1
(en)
*
|
2004-04-29 |
2010-09-02 |
Abbott Laboratories |
Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
|
US7880001B2
(en)
*
|
2004-04-29 |
2011-02-01 |
Abbott Laboratories |
Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme
|
WO2005113513A2
(en)
|
2004-05-12 |
2005-12-01 |
Chemocentryx |
Aryl sulfonamides
|
DE602005022089D1
(de)
*
|
2004-08-06 |
2010-08-12 |
Merck Sharp & Dohme |
Sulfonylverbindungen als hemmer von 11-beta-hydroxysteroiddehydrogenase-1
|
AU2005273986A1
(en)
*
|
2004-08-10 |
2006-02-23 |
Incyte Corporation |
Amido compounds and their use as pharmaceuticals
|
GB0418877D0
(en)
*
|
2004-08-24 |
2004-09-29 |
Univ Edinburgh |
Heart
|
US7776897B2
(en)
*
|
2004-09-16 |
2010-08-17 |
Astellas Pharma Inc. |
Triazole derivative or salt thereof
|
AU2005287004B2
(en)
*
|
2004-09-16 |
2011-03-17 |
The Regents Of The University Of California |
G-type peptides and other agents to ameliorate atherosclerosis and other pathologies
|
JP2008522980A
(ja)
|
2004-12-06 |
2008-07-03 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
小血管の構造および機能を改善するための方法
|
DK1830869T3
(da)
|
2004-12-24 |
2013-08-26 |
Spinifex Pharm Pty Ltd |
Fremgangsmåde til behandling eller profylakse
|
US7511175B2
(en)
|
2005-01-05 |
2009-03-31 |
Abbott Laboratories |
Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
|
US20090192198A1
(en)
|
2005-01-05 |
2009-07-30 |
Abbott Laboratories |
Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
|
JP5133702B2
(ja)
*
|
2005-01-05 |
2013-01-30 |
アボット・ラボラトリーズ |
11−β−ヒドロキシステロイドデヒドロゲナーゼ1型酵素の阻害薬
|
US8198331B2
(en)
*
|
2005-01-05 |
2012-06-12 |
Abbott Laboratories |
Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
|
MY148521A
(en)
*
|
2005-01-10 |
2013-04-30 |
Arena Pharm Inc |
Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto
|
WO2006094633A1
(en)
*
|
2005-03-03 |
2006-09-14 |
F. Hoffman-La Roche Ag |
1- sulfonyl-pi perdine- 3 -carboxyl i c acid amide derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase for the treatment of type ii diabetes mellitus
|
US20100120789A1
(en)
*
|
2005-03-24 |
2010-05-13 |
Nigel Vicker |
Compound
|
GB0506133D0
(en)
*
|
2005-03-24 |
2005-05-04 |
Sterix Ltd |
Compound
|
JP5140577B2
(ja)
|
2005-03-31 |
2013-02-06 |
タケダ カリフォルニア インコーポレイテッド |
ヒドロキシステロイドデヒドロゲナーゼ阻害剤
|
PL1928840T3
(pl)
|
2005-04-05 |
2012-01-31 |
Hoffmann La Roche |
1H-pirazolo-4-karboksyamidy, ich wytwarzanie i ich zastosowanie jako inhibitory dehydrogenazy 11-beta-hydroksysteroidowej
|
WO2006132197A1
(ja)
*
|
2005-06-07 |
2006-12-14 |
Shionogi & Co., Ltd. |
I型11βヒドロキシステロイド脱水素酵素阻害活性を有するヘテロ環化合物
|
US7579360B2
(en)
|
2005-06-09 |
2009-08-25 |
Bristol-Myers Squibb Company |
Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
US7572807B2
(en)
|
2005-06-09 |
2009-08-11 |
Bristol-Myers Squibb Company |
Heteroaryl 11-beta-hydroxysteroid dehydrogenase type I inhibitors
|
WO2006134604A1
(en)
*
|
2005-06-15 |
2006-12-21 |
Hetero Drugs Limited |
Combination composition of cholesterol absorption inhibitor and 3-hydroxy-3-methylglutaryl-coenzyme a (hmg-coa) reductase inhibitor
|
US7622492B2
(en)
|
2005-08-31 |
2009-11-24 |
Hoffmann-La Roche Inc. |
Pyrazolones as inhibitors of 11β-hydroxysteroid dehydrogenase
|
RU2008116844A
(ru)
|
2005-09-29 |
2009-11-10 |
Мерк энд Ко., Инк. (US) |
Ацилированные производные спиропиперидина как модуляторы рецептора меланокортина-4
|
BRPI0617501A2
(pt)
*
|
2005-10-20 |
2011-07-26 |
Merck & Co Inc |
composto ou um sal ou solvato farmaceuticamente aceitÁvel do mesmo, composiÇço farmacÊutica, e, uso de um composto
|
JP2009523727A
(ja)
*
|
2006-01-13 |
2009-06-25 |
メルク エンド カムパニー インコーポレーテッド |
11−ベータ−ヒドロキシステロイドデヒドロゲナーゼ−1のインヒビターとしてのトリアゾール誘導体
|
AU2007207055B2
(en)
|
2006-01-18 |
2011-06-02 |
F. Hoffmann-La Roche Ag |
Thiazoles as 11 beta-HSD1 inhibitors
|
WO2007088895A1
(ja)
*
|
2006-01-31 |
2007-08-09 |
Mochida Pharmaceutical Co., Ltd. |
3-アリールアミノ-1,2,4-トリアゾール誘導体
|
US20090082367A1
(en)
*
|
2006-03-16 |
2009-03-26 |
Astellas Pharma Inc. |
Triazole derivative or a salt thereof
|
AU2007229322B2
(en)
|
2006-03-20 |
2012-04-05 |
Novartis Ag |
Method of treatment or prophylaxis inflammatory pain
|
JP5240775B2
(ja)
|
2006-03-30 |
2013-07-17 |
塩野義製薬株式会社 |
I型11βヒドロキシステロイド脱水素酵素阻害活性を有するイソキサゾール誘導体およびイソチアゾール誘導体
|
PE20080251A1
(es)
|
2006-05-04 |
2008-04-25 |
Boehringer Ingelheim Int |
Usos de inhibidores de dpp iv
|
PL2046762T3
(pl)
*
|
2006-07-14 |
2011-07-29 |
Chemocentryx Inc |
Triazolilofenylobenzenosulfonamidy
|
US7718683B2
(en)
|
2006-07-14 |
2010-05-18 |
Chemocentryx, Inc. |
Triazolyl phenyl benzenesulfonamides
|
EP2049515B1
(en)
|
2006-07-14 |
2011-01-26 |
ChemoCentryx, Inc. |
Triazolyl pyridyl benzenesulfonamides as ccr2 or ccr9 modulators for the treatment of atherosclerosis
|
WO2008017381A1
(de)
|
2006-08-08 |
2008-02-14 |
Sanofi-Aventis |
Arylaminoaryl-alkyl-substituierte imidazolidin-2,4-dione, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und ihre verwendung
|
EP2698157B1
(en)
|
2006-09-22 |
2015-05-20 |
Merck Sharp & Dohme Corp. |
Method of treatment using fatty acid synthesis inhibitors
|
DE102006058207A1
(de)
*
|
2006-12-11 |
2008-06-19 |
Universitätsklinikum Schleswig-Holstein |
Verfahren zur Herstellung spezifischer Inhibitoren der 11beta-Hydroxysteroid-Dehydrogenase Typ 1 mit Nor-Oleanan- oder Nor-Ursan-Grundgerüsten
|
DE102007005045B4
(de)
|
2007-01-26 |
2008-12-18 |
Sanofi-Aventis |
Phenothiazin Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
US8106086B2
(en)
|
2007-04-02 |
2012-01-31 |
Msd K.K. |
Indoledione derivative
|
AR066063A1
(es)
*
|
2007-04-18 |
2009-07-22 |
Merck & Co Inc |
Derivados de triazol que son antagonistas de smo
|
US7776877B2
(en)
|
2007-06-22 |
2010-08-17 |
Chemocentryx, Inc. |
N-(2-(hetaryl)aryl) arylsulfonamides and N-(2-(hetaryl) hetaryl arylsulfonamides
|
EP2025674A1
(de)
|
2007-08-15 |
2009-02-18 |
sanofi-aventis |
Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
JP5736098B2
(ja)
|
2007-08-21 |
2015-06-17 |
アッヴィ・インコーポレイテッド |
中枢神経系障害を治療するための医薬組成物
|
WO2009032693A2
(en)
*
|
2007-08-28 |
2009-03-12 |
Uab Research Foundation |
Synthetic apolipoprotein e mimicking polypeptides and methods of use
|
AU2008296487A1
(en)
|
2007-08-28 |
2009-03-12 |
The Uab Research Foundation |
Synthetic apolipoprotein E mimicking polypeptides and methods of use
|
US8119658B2
(en)
|
2007-10-01 |
2012-02-21 |
Bristol-Myers Squibb Company |
Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
TWI465439B
(zh)
|
2008-07-03 |
2014-12-21 |
Astellas Pharma Inc |
三氮唑衍生物或其鹽
|
US8470841B2
(en)
|
2008-07-09 |
2013-06-25 |
Sanofi |
Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
|
WO2010051236A1
(en)
|
2008-10-30 |
2010-05-06 |
Merck Sharp & Dohme Corp. |
Isonicotinamide orexin receptor antagonists
|
JO2870B1
(en)
|
2008-11-13 |
2015-03-15 |
ميرك شارب اند دوهم كورب |
Amino Tetra Hydro Pirans as Inhibitors of Peptide Dipeptide IV for the Treatment or Prevention of Diabetes
|
AU2009314200B2
(en)
|
2008-11-17 |
2011-11-17 |
Merck Sharp & Dohme Corp. |
Substituted bicyclic amines for the treatment of diabetes
|
WO2010068601A1
(en)
|
2008-12-08 |
2010-06-17 |
Sanofi-Aventis |
A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
|
CA2745882A1
(en)
*
|
2008-12-12 |
2011-06-06 |
Merck Sharp & Dohme Corp. |
Novel crystalline forms of an inhibitor of 11-beta-hydroxysteroid dehydrogenase type 1
|
ES2350077B1
(es)
|
2009-06-04 |
2011-11-04 |
Laboratorios Salvat, S.A. |
Compuestos inhibidores de 11beta-hidroxiesteroide deshidrogenasa de tipo 1.
|
WO2011011506A1
(en)
|
2009-07-23 |
2011-01-27 |
Schering Corporation |
Spirocyclic oxazepine compounds as stearoyl-coenzyme a delta-9 desaturase inhibitors
|
CA2768577A1
(en)
|
2009-07-23 |
2011-01-27 |
Schering Corporation |
Benzo-fused oxazepine compounds as stearoyl-coenzyme a delta-9 desaturase inhibitors
|
WO2011019538A1
(en)
|
2009-08-13 |
2011-02-17 |
Merck Sharp & Dohme Corp. |
Substituted cyclopropyl compounds, compositions containing such compounds and methods of treatment
|
CA2771278A1
(en)
|
2009-08-26 |
2011-03-03 |
Sanofi |
Novel crystalline heteroaromatic fluoroglycoside hydrates, pharmaceuticals comprising these compounds and their use
|
WO2011028455A1
(en)
|
2009-09-02 |
2011-03-10 |
Merck Sharp & Dohme Corp. |
Aminotetrahydropyrans as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
|
CN108558740B
(zh)
|
2010-01-27 |
2021-10-19 |
艾尼纳制药公司 |
S1p1受体调节剂及其盐的制备方法
|
US8853212B2
(en)
|
2010-02-22 |
2014-10-07 |
Merck Sharp & Dohme Corp |
Substituted aminotetrahydrothiopyrans and derivatives thereof as dipeptidyl peptidase-IV inhibitors for the treatment of diabetes
|
WO2011107494A1
(de)
|
2010-03-03 |
2011-09-09 |
Sanofi |
Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
|
JP5655633B2
(ja)
|
2010-03-04 |
2015-01-21 |
セントラル硝子株式会社 |
パーフルオロアルカンスルフィン酸塩の製造方法
|
US8980929B2
(en)
|
2010-05-21 |
2015-03-17 |
Merck Sharp & Dohme Corp. |
Substituted seven-membered heterocyclic compounds as dipeptidyl peptidase-iv inhibitors for the treatment of diabetes
|
EP2582709B1
(de)
|
2010-06-18 |
2018-01-24 |
Sanofi |
Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
|
US8530413B2
(en)
|
2010-06-21 |
2013-09-10 |
Sanofi |
Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
|
TW201215388A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Sa |
(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
|
TW201221505A
(en)
|
2010-07-05 |
2012-06-01 |
Sanofi Sa |
Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
|
TW201215387A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Aventis |
Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
|
US8742110B2
(en)
|
2010-08-18 |
2014-06-03 |
Merck Sharp & Dohme Corp. |
Spiroxazolidinone compounds
|
UA112418C2
(uk)
|
2010-09-07 |
2016-09-12 |
Астеллас Фарма Інк. |
Терапевтичний болезаспокійливий засіб
|
AU2011305525B2
(en)
|
2010-09-22 |
2016-08-18 |
Arena Pharmaceuticals, Inc. |
Modulators of the GPR119 receptor and the treatment of disorders related thereto
|
EP2683699B1
(de)
|
2011-03-08 |
2015-06-24 |
Sanofi |
Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
EP2683703B1
(de)
|
2011-03-08 |
2015-05-27 |
Sanofi |
Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
WO2012120054A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
EP2683704B1
(de)
|
2011-03-08 |
2014-12-17 |
Sanofi |
Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
EP2683702B1
(de)
|
2011-03-08 |
2014-12-24 |
Sanofi |
Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
US8809325B2
(en)
|
2011-03-08 |
2014-08-19 |
Sanofi |
Benzyl-oxathiazine derivatives substituted with adamantane and noradamantane, medicaments containing said compounds and use thereof
|
US8901114B2
(en)
|
2011-03-08 |
2014-12-02 |
Sanofi |
Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof
|
US8871758B2
(en)
|
2011-03-08 |
2014-10-28 |
Sanofi |
Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
|
EP2683701B1
(de)
|
2011-03-08 |
2014-12-24 |
Sanofi |
Mit benzyl- oder heteromethylengruppen substituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
AU2012240122B2
(en)
|
2011-04-08 |
2016-08-25 |
Merck Sharp & Dohme Corp. |
Substituted cyclopropyl compounds, compositions containing such compounds and methods of treatment
|
US20140088124A1
(en)
|
2011-06-02 |
2014-03-27 |
Robert J. DeVita |
Imidazole derivatives
|
JP2014517036A
(ja)
|
2011-06-16 |
2014-07-17 |
メルク・シャープ・アンド・ドーム・コーポレーション |
置換シクロプロピル化合物、そのような化合物を含有する組成物および治療方法
|
WO2013037390A1
(en)
|
2011-09-12 |
2013-03-21 |
Sanofi |
6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
WO2013045413A1
(en)
|
2011-09-27 |
2013-04-04 |
Sanofi |
6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
US9422266B2
(en)
|
2011-09-30 |
2016-08-23 |
Merck Sharp & Dohme Corp. |
Substituted cyclopropyl compounds, compositions containing such compounds and methods of treatment
|
AR088352A1
(es)
|
2011-10-19 |
2014-05-28 |
Merck Sharp & Dohme |
Antagonistas del receptor de 2-piridiloxi-4-nitrilo orexina
|
WO2013062838A1
(en)
|
2011-10-24 |
2013-05-02 |
Merck Sharp & Dohme Corp. |
Substituted piperidinyl compounds useful as gpr119 agonists
|
WO2013068328A1
(en)
|
2011-11-07 |
2013-05-16 |
Intervet International B.V. |
Bicyclo [2.2.2] octan-1-ylcarboxylic acid compounds as dgat-1 inhibitors
|
WO2013068439A1
(en)
|
2011-11-09 |
2013-05-16 |
Intervet International B.V. |
4-amino-5-oxo-7,8-dihydropyrimido[5, 4 -f] [1, 4] oxazepine compounds as dgat1 inhibitors
|
WO2013074388A1
(en)
|
2011-11-15 |
2013-05-23 |
Merck Sharp & Dohme Corp. |
Substituted cyclopropyl compounds useful as gpr119 agonists
|
US9073930B2
(en)
|
2012-02-17 |
2015-07-07 |
Merck Sharp & Dohme |
Dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
|
IN2014DN09640A
(es)
|
2012-04-16 |
2015-07-31 |
Kaneq Pharma Inc |
|
EP2874622A4
(en)
|
2012-07-23 |
2015-12-30 |
Merck Sharp & Dohme |
TREATMENT OF DIABETES WITH DIPEPTIDYLPEPTIDASE IV INHIBITORS
|
WO2015089809A1
(en)
|
2013-12-19 |
2015-06-25 |
Merck Sharp & Dohme Corp. |
Antidiabetic substituted heteroaryl compounds
|
EP3097101B1
(en)
|
2014-01-24 |
2020-12-23 |
Merck Sharp & Dohme Corp. |
Isoquinoline derivatives as mgat2 inhibitors
|
WO2015176267A1
(en)
|
2014-05-22 |
2015-11-26 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
EP3177282B1
(en)
|
2014-08-08 |
2021-10-06 |
Merck Sharp & Dohme Corp. |
Antidiabetic bicyclic compounds
|
EP3177285B1
(en)
|
2014-08-08 |
2020-09-23 |
Merck Sharp & Dohme Corp. |
[5,6]-fused bicyclic antidiabetic compounds
|
EP3177287B1
(en)
|
2014-08-08 |
2022-02-23 |
Merck Sharp & Dohme Corp. |
Antidiabetic bicyclic compounds
|
EA201790914A1
(ru)
|
2014-10-24 |
2017-08-31 |
Мерк Шарп И Доум Корп. |
Коагонисты рецепторов глюкагона и glp-1
|
WO2016112075A1
(en)
|
2015-01-06 |
2016-07-14 |
Arena Pharmaceuticals, Inc. |
Methods of treating conditions related to the s1p1 receptor
|
BR112017027656B1
(pt)
|
2015-06-22 |
2023-12-05 |
Arena Pharmaceuticals, Inc. |
Hábito cristalino de placa livre de sal de l-arginina de ácido (r)-2-(7-(4- ciclopentil-3-(trifluorometil)benzilóxi)- 1,2,3,4-tetra-hidrociclo-penta[b]indol-3- il)acético, composição farmacêutica que o compreende, seus usos e método de preparação do mesmo
|
EP3359191A4
(en)
|
2015-10-05 |
2019-05-29 |
Merck Sharp & Dohme Corp. |
ANTIBODY-PEPTIDE CONJUGATES HAVING AGONIST ACTIVITY AT GLUCAGON AND PEPTIDE-1 RECEPTORS SIMILAR TO GLUCAGON
|
EP3235813A1
(en)
|
2016-04-19 |
2017-10-25 |
Cidqo 2012, S.L. |
Aza-tetra-cyclo derivatives
|
TW201808888A
(zh)
|
2016-05-05 |
2018-03-16 |
嘉來克生命科學有限責任公司 |
整合應激途徑之調節劑
|
TW201808903A
(zh)
|
2016-05-05 |
2018-03-16 |
嘉來克生命科學有限責任公司 |
整合應激途徑之調節劑
|
TW201808914A
(zh)
|
2016-05-05 |
2018-03-16 |
嘉來克生命科學有限責任公司 |
整合應激途徑之調節劑
|
WO2017205425A1
(en)
*
|
2016-05-24 |
2017-11-30 |
President And Fellows Of Harvard College |
Compounds for organic light emitting diode materials
|
WO2017201683A1
(en)
|
2016-05-25 |
2017-11-30 |
Merck Sharp & Dohme Corp. |
Substituted tetrahydroisoquinoline compounds useful as gpr120 agonists
|
WO2018034917A1
(en)
|
2016-08-15 |
2018-02-22 |
Merck Sharp & Dohme Corp. |
Compounds useful for altering the levels of bile acids for the treatment of diabetes and cardiometabolic disease
|
US10414774B2
(en)
|
2016-08-15 |
2019-09-17 |
Merck Sharp & Dohme Corp. |
Compound useful for altering the levels of bile acids for the treatment of diabetes and cardiometabolc disease
|
WO2018107415A1
(en)
|
2016-12-15 |
2018-06-21 |
Merck Sharp & Dohme Corp. |
Hydroxy isoxazole compounds useful as gpr120 agonists
|
AU2018220521A1
(en)
|
2017-02-16 |
2019-09-05 |
Arena Pharmaceuticals, Inc. |
Compounds and methods for treatment of primary biliary cholangitis
|
EP3665156A4
(en)
|
2017-08-09 |
2021-04-28 |
Denali Therapeutics Inc. |
COMPOUNDS, COMPOSITIONS, AND PROCEDURES
|
CN111094255B
(zh)
*
|
2017-09-14 |
2023-10-03 |
第一三共株式会社 |
具有环状结构的化合物
|
MX2020004537A
(es)
*
|
2017-11-02 |
2020-10-05 |
Calico Life Sciences Llc |
Moduladores de la vía integrada del estrés.
|
CN112166113A
(zh)
|
2017-11-02 |
2021-01-01 |
卡里科生命科学有限责任公司 |
整合应激通路的调节剂
|
US20210205277A1
(en)
*
|
2017-11-02 |
2021-07-08 |
Calico Life Sciences Llc |
Modulators of the integrated stress pathway
|
TWI832295B
(zh)
|
2018-10-11 |
2024-02-11 |
美商嘉來克生命科學有限責任公司 |
整合應激路徑之前藥調節劑
|
CR20210426A
(es)
|
2019-02-13 |
2021-09-30 |
Denali Therapeutics Inc |
Compuestos, composiciones y métodos
|
TW202045476A
(zh)
|
2019-02-13 |
2020-12-16 |
美商默沙東藥廠 |
5-烷基吡咯啶食慾素受體促效劑
|
WO2020205688A1
(en)
|
2019-04-04 |
2020-10-08 |
Merck Sharp & Dohme Corp. |
Inhibitors of histone deacetylase-3 useful for the treatment of cancer, inflammation, neurodegeneration diseases and diabetes
|
EP4010314B1
(en)
|
2019-08-08 |
2024-02-28 |
Merck Sharp & Dohme LLC |
Heteroaryl pyrrolidine and piperidine orexin receptor agonists
|
EP3842061A1
(en)
|
2019-12-23 |
2021-06-30 |
Merck Sharp & Dohme Corp. |
Stapled triazole co-agonists of the glucagon and glp-1 receptors
|
EP3842060A1
(en)
|
2019-12-23 |
2021-06-30 |
Merck Sharp & Dohme Corp. |
Stapled lactam co-agonists of the glucagon and glp-1 receptors
|
EP3842449A1
(en)
|
2019-12-23 |
2021-06-30 |
Merck Sharp & Dohme Corp. |
Stapled olefin co-agonists of the glucagon and glp-1 receptors
|
BR112023002957A2
(pt)
|
2020-08-18 |
2023-04-04 |
Merck Sharp & Dohme Llc |
Composto, composição farmacêutica, e, métodos para tratar narcolepsia e para tratar hipersonia em um sujeito mamífero
|