YU40202A - Novi derivati tiazolidindiona kao antidijabetički agensi - Google Patents
Novi derivati tiazolidindiona kao antidijabetički agensiInfo
- Publication number
- YU40202A YU40202A YU40202A YUP40202A YU40202A YU 40202 A YU40202 A YU 40202A YU 40202 A YU40202 A YU 40202A YU P40202 A YUP40202 A YU P40202A YU 40202 A YU40202 A YU 40202A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- antidiabetic agents
- thiazolidinedione derivatives
- antidiabetic
- utilization
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Oncology (AREA)
- Emergency Medicine (AREA)
- Communicable Diseases (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Dati pronalazak se odnosi na jedinjenja opšte formule (I), na njihove moguće farmaceutski prihvatljive soli i tautomerne oblike. Dati pronalazak se takodje odnosi na postupak za njihovu proizvodnju i na njihovu upotrebu kao antidijabetika i hipoglikemičnih agenasa, samih ili u kombinaciji sa ostalim antidijabetičkim agensima, kao što su sulfoniluree ili biguanidi, kao i za lečenje komplikacija povezanih sa otpornošću na insulin, kao što je hipertenzija, hiperurikemija ili ostala kardiovaskularna, metabolička, endokrina stanja, ili ostala stanja povezana sa dijabetesom.[The invention relates to compounds of general formula (I), to their possible pharmaceutically acceptable salts and tautomeric forms. The invention also relates to a method for obtaining said compounds and to their utilization as antidiabetic and hypolipidemic agents, by themselves or combined with other antidiabetic agents such as sulfonylureas or biguanides, as well as to their utilization in the treatment of complications associated with insulin resistance such as hypertension, hyperuricemia or other cardiovascular, metabolic and endocrine disorders or other disorders associated with diabetes.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES009902533A ES2156574B1 (es) | 1999-11-18 | 1999-11-18 | Nuevos derivados de tiazolidindiona como agentes antidiabeticos |
Publications (1)
Publication Number | Publication Date |
---|---|
YU40202A true YU40202A (sh) | 2006-01-16 |
Family
ID=8310628
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU40202A YU40202A (sh) | 1999-11-18 | 2000-11-15 | Novi derivati tiazolidindiona kao antidijabetički agensi |
Country Status (37)
Country | Link |
---|---|
US (1) | US7001910B1 (sh) |
EP (1) | EP1231211B1 (sh) |
JP (1) | JP2003514817A (sh) |
KR (1) | KR100518110B1 (sh) |
CN (1) | CN1159314C (sh) |
AP (1) | AP1330A (sh) |
AR (1) | AR031080A1 (sh) |
AT (1) | ATE241622T1 (sh) |
AU (1) | AU770045B2 (sh) |
BG (1) | BG106699A (sh) |
BR (1) | BR0015613A (sh) |
CA (1) | CA2391913A1 (sh) |
CO (1) | CO5261560A1 (sh) |
CR (1) | CR6640A (sh) |
CZ (1) | CZ20021654A3 (sh) |
DE (1) | DE60003072T2 (sh) |
DK (1) | DK1231211T3 (sh) |
EA (1) | EA004301B1 (sh) |
EE (1) | EE200200254A (sh) |
ES (2) | ES2156574B1 (sh) |
GE (1) | GEP20043240B (sh) |
HR (1) | HRP20020426A2 (sh) |
HU (1) | HUP0203478A2 (sh) |
IL (1) | IL149634A0 (sh) |
IS (1) | IS2014B (sh) |
MA (1) | MA26844A1 (sh) |
MX (1) | MXPA02005011A (sh) |
NO (2) | NO20022336L (sh) |
NZ (1) | NZ519264A (sh) |
OA (1) | OA12089A (sh) |
PE (1) | PE20010858A1 (sh) |
PL (1) | PL354877A1 (sh) |
PT (1) | PT1231211E (sh) |
SK (1) | SK6752002A3 (sh) |
WO (1) | WO2001036416A1 (sh) |
YU (1) | YU40202A (sh) |
ZA (1) | ZA200203906B (sh) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2174748B1 (es) * | 2001-01-31 | 2003-09-16 | Vita Lab | Nueva sal de tiazolidindiona y sus polimorfos como agentes antidiabeticos y procedimiento para la obtencion de los mismos. |
KR100450700B1 (ko) * | 2002-03-22 | 2004-10-01 | 주식회사종근당 | 티아졸리딘디온 유도체 화합물 및 이를 함유하는 약제학적조성물 |
US7713983B2 (en) | 2003-03-03 | 2010-05-11 | Vertex Pharmaceuticals Incorporated | Quinazolines useful as modulators of ion channels |
CL2004000409A1 (es) * | 2003-03-03 | 2005-01-07 | Vertex Pharma | Compuestos derivados de 2-(cilo sustituido)-1-(amino u oxi sustituido)-quinazolina, inhibidores de canales ionicos de sodio y calcio dependientes de voltaje; composicion farmaceutica; y uso del compuesto en el tratamiento de dolor agudo, cronico, neu |
US20050014732A1 (en) * | 2003-03-14 | 2005-01-20 | Pharmacia Corporation | Combination of an aldosterone receptor antagonist and an anti-diabetic agent |
US8283354B2 (en) | 2004-09-02 | 2012-10-09 | Vertex Pharmaceuticals Incorporated | Quinazolines useful as modulators of ion channels |
US7928107B2 (en) | 2004-09-02 | 2011-04-19 | Vertex Pharmaceuticals Incorporated | Quinazolines useful as modulators of ion channels |
CZ297347B6 (cs) * | 2004-09-21 | 2006-11-15 | Zentiva, A. S. | Zpusob prípravy rosiglitazonu |
JP5546372B2 (ja) * | 2010-06-30 | 2014-07-09 | 積水メディカル株式会社 | ベンジルヒダントイン化合物の製造法 |
WO2016184895A1 (en) | 2015-05-18 | 2016-11-24 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Means for detecting or measuring a biological activity of a botulinum toxin |
US10689374B1 (en) | 2019-07-12 | 2020-06-23 | United Arab Emirates University | Pyrimidine-thiazolidinone derivatives |
US10702525B1 (en) * | 2019-09-04 | 2020-07-07 | United Arab Emirates University | Pyrimidine derivatives as anti-diabetic agents |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR240698A1 (es) * | 1985-01-19 | 1990-09-28 | Takeda Chemical Industries Ltd | Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales |
SG59988A1 (en) * | 1987-09-04 | 1999-02-22 | Beecham Group Plc | Substituted thiazolidinedione derivatives |
GB9023583D0 (en) * | 1990-10-30 | 1990-12-12 | Beecham Group Plc | Novel compounds |
-
1999
- 1999-11-18 ES ES009902533A patent/ES2156574B1/es not_active Expired - Fee Related
-
2000
- 2000-11-06 AR ARP000105830A patent/AR031080A1/es unknown
- 2000-11-07 PE PE2000001189A patent/PE20010858A1/es not_active Application Discontinuation
- 2000-11-14 CO CO00086452A patent/CO5261560A1/es not_active Application Discontinuation
- 2000-11-15 AT AT00974559T patent/ATE241622T1/de not_active IP Right Cessation
- 2000-11-15 MX MXPA02005011A patent/MXPA02005011A/es active IP Right Grant
- 2000-11-15 CN CNB008166412A patent/CN1159314C/zh not_active Expired - Fee Related
- 2000-11-15 YU YU40202A patent/YU40202A/sh unknown
- 2000-11-15 DK DK00974559T patent/DK1231211T3/da active
- 2000-11-15 OA OA1200200148A patent/OA12089A/en unknown
- 2000-11-15 WO PCT/ES2000/000432 patent/WO2001036416A1/es not_active Application Discontinuation
- 2000-11-15 AU AU12815/01A patent/AU770045B2/en not_active Ceased
- 2000-11-15 IL IL14963400A patent/IL149634A0/xx unknown
- 2000-11-15 EP EP00974559A patent/EP1231211B1/en not_active Expired - Lifetime
- 2000-11-15 GE GEAP20006452A patent/GEP20043240B/en unknown
- 2000-11-15 PT PT00974559T patent/PT1231211E/pt unknown
- 2000-11-15 NZ NZ519264A patent/NZ519264A/en unknown
- 2000-11-15 BR BR0015613-2A patent/BR0015613A/pt not_active IP Right Cessation
- 2000-11-15 CZ CZ20021654A patent/CZ20021654A3/cs unknown
- 2000-11-15 CA CA002391913A patent/CA2391913A1/en not_active Abandoned
- 2000-11-15 KR KR10-2002-7006298A patent/KR100518110B1/ko not_active IP Right Cessation
- 2000-11-15 DE DE60003072T patent/DE60003072T2/de not_active Expired - Fee Related
- 2000-11-15 ES ES00974559T patent/ES2199878T3/es not_active Expired - Lifetime
- 2000-11-15 US US10/130,576 patent/US7001910B1/en not_active Expired - Fee Related
- 2000-11-15 EE EEP200200254A patent/EE200200254A/xx unknown
- 2000-11-15 AP APAP/P/2002/002512A patent/AP1330A/en active
- 2000-11-15 JP JP2001538905A patent/JP2003514817A/ja active Pending
- 2000-11-15 SK SK675-2002A patent/SK6752002A3/sk unknown
- 2000-11-15 EA EA200200470A patent/EA004301B1/ru not_active IP Right Cessation
- 2000-11-15 PL PL00354877A patent/PL354877A1/xx not_active IP Right Cessation
- 2000-11-15 HU HU0203478A patent/HUP0203478A2/hu unknown
-
2002
- 2002-05-14 BG BG106699A patent/BG106699A/bg unknown
- 2002-05-15 NO NO20022336A patent/NO20022336L/no not_active Application Discontinuation
- 2002-05-15 HR HR20020426A patent/HRP20020426A2/hr not_active Application Discontinuation
- 2002-05-15 MA MA26638A patent/MA26844A1/fr unknown
- 2002-05-15 IS IS6386A patent/IS2014B/is unknown
- 2002-05-15 CR CR6640A patent/CR6640A/es not_active Application Discontinuation
- 2002-05-16 NO NO20022379A patent/NO20022379D0/no unknown
- 2002-05-16 ZA ZA200203906A patent/ZA200203906B/en unknown
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