EA200000274A2 - Способы получения и промежуточные соединения для получения противораковых соединений - Google Patents
Способы получения и промежуточные соединения для получения противораковых соединенийInfo
- Publication number
- EA200000274A2 EA200000274A2 EA200000274A EA200000274A EA200000274A2 EA 200000274 A2 EA200000274 A2 EA 200000274A2 EA 200000274 A EA200000274 A EA 200000274A EA 200000274 A EA200000274 A EA 200000274A EA 200000274 A2 EA200000274 A2 EA 200000274A2
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- obtaining
- compounds
- methods
- tray
- intermediate connections
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/94—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
- C22B—PRODUCTION AND REFINING OF METALS; PRETREATMENT OF RAW MATERIALS
- C22B15/00—Obtaining copper
- C22B15/0002—Preliminary treatment
- C22B15/0004—Preliminary treatment without modification of the copper constituent
-
- C—CHEMISTRY; METALLURGY
- C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
- C22B—PRODUCTION AND REFINING OF METALS; PRETREATMENT OF RAW MATERIALS
- C22B15/00—Obtaining copper
- C22B15/0063—Hydrometallurgy
- C22B15/0065—Leaching or slurrying
- C22B15/0067—Leaching or slurrying with acids or salts thereof
- C22B15/0071—Leaching or slurrying with acids or salts thereof containing sulfur
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P10/00—Technologies related to metal processing
- Y02P10/20—Recycling
Abstract
Данное изобретение относится к способам получения и промежуточным соединениям для получения соединений формулы 1и их фармацевтически приемлемых солей и сольватов, а также родственным по структуре соединениям, где R, Rи Rопределены как указано в описании. Вышеназванные соединения применимы при лечении заболеваний с гиперпролиферацией, таких как разновидности рака у млекопитающих.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12707299P | 1999-03-31 | 1999-03-31 |
Publications (3)
Publication Number | Publication Date |
---|---|
EA200000274A2 true EA200000274A2 (ru) | 2000-10-30 |
EA200000274A3 EA200000274A3 (ru) | 2003-02-27 |
EA004654B1 EA004654B1 (ru) | 2004-06-24 |
Family
ID=22428179
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200201244A EA005561B1 (ru) | 1999-03-31 | 2000-03-30 | Способ получения промежуточных соединений, применимых для получения противораковых соединений |
EA200000274A EA004654B1 (ru) | 1999-03-31 | 2000-03-30 | Способы получения и промежуточные соединения для получения противораковых соединений |
EA200201245A EA005892B1 (ru) | 1999-03-31 | 2000-03-30 | Способ получения противораковых соединений |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200201244A EA005561B1 (ru) | 1999-03-31 | 2000-03-30 | Способ получения промежуточных соединений, применимых для получения противораковых соединений |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200201245A EA005892B1 (ru) | 1999-03-31 | 2000-03-30 | Способ получения противораковых соединений |
Country Status (50)
Families Citing this family (68)
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CN104706637A (zh) | 2006-05-18 | 2015-06-17 | 卫材R&D管理有限公司 | 针对甲状腺癌的抗肿瘤剂 |
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US20090124642A1 (en) * | 2007-08-23 | 2009-05-14 | Augusto Canavesi | Crystalline forms of Erlotinib HCI and formulations thereof |
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KR101506062B1 (ko) * | 2008-01-29 | 2015-03-25 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 혈관 저해 물질과 탁산의 병용 |
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CN102267952B (zh) * | 2011-06-21 | 2013-12-11 | 天津市汉康医药生物技术有限公司 | 喹唑啉类化合物、其制备方法和用途 |
CN103420924B (zh) * | 2012-05-25 | 2016-08-31 | 浙江九洲药业股份有限公司 | 一种盐酸埃罗替尼晶型a的制备方法 |
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CN103333124B (zh) * | 2013-05-28 | 2015-03-25 | 埃斯特维华义制药有限公司 | 一种制备盐酸厄洛替尼晶型f的方法 |
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2000
- 2000-03-03 YU YU13200A patent/YU13200A/sh unknown
- 2000-03-03 RS YUP-132/00A patent/RS49836B/sr unknown
- 2000-03-10 OA OA1200000071A patent/OA11335A/en unknown
- 2000-03-14 CR CR6165A patent/CR6165A/es unknown
- 2000-03-17 PA PA20008491901A patent/PA8491901A1/es unknown
- 2000-03-20 DK DK00302256T patent/DK1044969T3/da active
- 2000-03-20 EP EP00302256A patent/EP1044969B1/en not_active Expired - Lifetime
- 2000-03-20 AT AT00302256T patent/ATE348098T1/de not_active IP Right Cessation
- 2000-03-20 PT PT00302256T patent/PT1044969E/pt unknown
- 2000-03-20 ES ES00302256T patent/ES2278578T3/es not_active Expired - Lifetime
- 2000-03-20 DE DE60032275T patent/DE60032275T2/de not_active Expired - Lifetime
- 2000-03-21 IS IS5411A patent/IS2468B/is unknown
- 2000-03-22 CO CO00020444A patent/CO5160273A1/es unknown
- 2000-03-23 IL IL13524500A patent/IL135245A0/xx not_active IP Right Cessation
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- 2000-03-27 UA UA2000031727A patent/UA70928C2/ru unknown
- 2000-03-27 UA UA20040503766A patent/UA80955C2/uk unknown
- 2000-03-27 SK SK444-2000A patent/SK287339B6/sk not_active IP Right Cessation
- 2000-03-27 EG EG20000364A patent/EG22506A/xx active
- 2000-03-28 AU AU22620/00A patent/AU781402B2/en not_active Expired
- 2000-03-28 BG BG104278A patent/BG65194B1/bg unknown
- 2000-03-29 AP APAP/P/2000/001778A patent/AP1265A/en active
- 2000-03-29 CA CA002427221A patent/CA2427221C/en not_active Expired - Lifetime
- 2000-03-29 DZ DZ000059A patent/DZ3030A1/xx active
- 2000-03-29 TN TNTNSN00064A patent/TNSN00064A1/fr unknown
- 2000-03-29 MA MA25940A patent/MA25087A1/fr unknown
- 2000-03-29 AP APAP/P/2003/002757D patent/AP1655A/en active
- 2000-03-29 MY MYPI20001252A patent/MY136270A/en unknown
- 2000-03-29 AR ARP000101413A patent/AR018705A1/es active IP Right Grant
- 2000-03-29 ZA ZA200001586A patent/ZA200001586B/xx unknown
- 2000-03-29 JP JP2000091300A patent/JP3420549B2/ja not_active Expired - Lifetime
- 2000-03-29 UY UY26086A patent/UY26086A1/es not_active Application Discontinuation
- 2000-03-29 CA CA002302965A patent/CA2302965C/en not_active Expired - Lifetime
- 2000-03-30 NO NO20001648A patent/NO321952B1/no not_active IP Right Cessation
- 2000-03-30 CZ CZ20001155A patent/CZ299426B6/cs not_active IP Right Cessation
- 2000-03-30 PL PL00339330A patent/PL339330A1/xx not_active Application Discontinuation
- 2000-03-30 PE PE2000000277A patent/PE20001599A1/es not_active Application Discontinuation
- 2000-03-30 EA EA200201244A patent/EA005561B1/ru not_active IP Right Cessation
- 2000-03-30 GT GT200000037A patent/GT200000037A/es unknown
- 2000-03-30 EA EA200000274A patent/EA004654B1/ru not_active IP Right Cessation
- 2000-03-30 KR KR1020000016386A patent/KR100430210B1/ko active IP Right Grant
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- 2000-03-30 SV SV2000000047A patent/SV2002000047A/es not_active Application Discontinuation
- 2000-03-30 HU HU0001353A patent/HU227698B1/hu unknown
- 2000-03-30 EA EA200201245A patent/EA005892B1/ru not_active IP Right Cessation
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- 2000-03-30 US US09/538,635 patent/US6476040B1/en not_active Expired - Lifetime
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2001
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2002
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- 2002-12-12 JP JP2002360742A patent/JP4074509B2/ja not_active Expired - Lifetime
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