EA018110B1 - Пептиды с пониженным уровнем образования димеров - Google Patents
Пептиды с пониженным уровнем образования димеров Download PDFInfo
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- EA018110B1 EA018110B1 EA201070270A EA201070270A EA018110B1 EA 018110 B1 EA018110 B1 EA 018110B1 EA 201070270 A EA201070270 A EA 201070270A EA 201070270 A EA201070270 A EA 201070270A EA 018110 B1 EA018110 B1 EA 018110B1
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- peptide
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- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
- C07K14/43531—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from mites
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- C07K16/16—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from plants
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56977—HLA or MHC typing
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- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
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- C—CHEMISTRY; METALLURGY
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- C07K2319/00—Fusion polypeptide
Landscapes
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- Life Sciences & Earth Sciences (AREA)
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Applications Claiming Priority (4)
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| GB0715949A GB0715949D0 (en) | 2007-08-15 | 2007-08-15 | Peptide with improved solubility |
| GB0716224A GB0716224D0 (en) | 2007-08-20 | 2007-08-20 | Peptides for vaccine |
| GB0723337A GB0723337D0 (en) | 2007-11-28 | 2007-11-28 | Peptide with reduced dimer formation |
| PCT/GB2008/002779 WO2009022155A2 (en) | 2007-08-15 | 2008-08-15 | Peptide with reduced dimer formation |
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| EA201070270A1 EA201070270A1 (ru) | 2010-08-30 |
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| EA201070270A EA018110B1 (ru) | 2007-08-15 | 2008-08-15 | Пептиды с пониженным уровнем образования димеров |
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| GB0710529D0 (en) | 2007-06-01 | 2007-07-11 | Circassia Ltd | Vaccine |
| WO2009022155A2 (en) | 2007-08-15 | 2009-02-19 | Circassia Limited | Peptide with reduced dimer formation |
| US8821887B2 (en) | 2008-08-15 | 2014-09-02 | Circassia Limited | T-cell antigen peptide from allergen for stimulation of IL-10 production |
| DK2153841T4 (en) * | 2008-08-15 | 2016-02-15 | Circassia Ltd | Vaccine comprising Amb a 1 peptides for use in the treatment of ambrosieallergi |
| GB0821806D0 (en) * | 2008-11-28 | 2009-01-07 | Circassia Ltd | Compositions with reduced dimer formation |
| BRPI1008802A2 (pt) * | 2009-02-05 | 2016-03-08 | Circassia Ltd | composição, vetor e formulação farmacêutica para o uso na prevenção ou tratamento de alergia a pólen de grama por tolerização, produto, e, método in vitro para determinar se as células t reconhecem uma composição |
| KR101488902B1 (ko) * | 2009-10-08 | 2015-02-03 | 주식회사이언메딕스 | 실내 공기유래 세포밖 소포체를 포함하는 조성물 및 이의 용도 |
| WO2011085783A1 (de) * | 2010-01-14 | 2011-07-21 | Merck Patent Gmbh | VARIANTEN DER GRUPPE 5-ALLERGENE DER SÜßGRÄSER MIT REDUZIERTER ALLERGENITÄT DURCH MUTAGENESE VON PROLINRESTEN |
| GB201002559D0 (en) * | 2010-02-15 | 2010-03-31 | Circassia Ltd | Birch peptides for vaccine |
| WO2011151449A1 (en) * | 2010-06-03 | 2011-12-08 | Alk-Abelló A/S | Pharmaceutical product comprising mite allergen extract(s) and a method for the manufacture thereof |
| EP2982684A1 (en) * | 2010-09-24 | 2016-02-10 | Maria R. Diaz-Torres | Peptides deriving from Alternaria Alternata major allergen Alt a 1 |
| EP2460824A1 (en) * | 2010-12-01 | 2012-06-06 | Biomay Ag | Hypoallergenic polypeptides for the treatment of house dust mite allergy |
| CN118078979A (zh) | 2011-04-29 | 2024-05-28 | 西莱克塔生物科技公司 | 用于降低针对治疗性蛋白的免疫应答的致耐受性合成纳米载体 |
| EP3299379A1 (en) * | 2011-06-15 | 2018-03-28 | ASIT BioTech S.A. | A method for the production of hydrolyzed allergens |
| CA2843274A1 (en) | 2011-07-29 | 2013-02-07 | Selecta Biosciences, Inc. | Synthetic nanocarriers that generate humoral and cytotoxic t lymphocyte (ctl) immune responses |
| GB201208293D0 (en) * | 2012-05-11 | 2012-06-20 | Circassia Ltd | Hydrochlorice salt of peptide |
| GB201209868D0 (en) * | 2012-06-01 | 2012-07-18 | Circassia Ltd | Alternaria peptides |
| GB201209862D0 (en) | 2012-06-01 | 2012-07-18 | Circassia Ltd | Cladosporium peptides |
| DK2914286T3 (da) | 2012-10-30 | 2021-11-08 | Aravax Pty Ltd | Hidtil ukendte immunterapeutiske molekyler og anvendelser deraf |
| US10434088B2 (en) | 2013-05-03 | 2019-10-08 | Selecta Biosciences, Inc. | Methods related to administering immunosuppressants and therapeutic macromolecules at a reduced pharmacodynamically effective dose |
| US20160130311A1 (en) * | 2013-06-05 | 2016-05-12 | Maria R. Diaz-Torres | T cell epitopes derived from alt a 1 or alt a 5 for the treatment of alternaria alternata allergy |
| HK1223019A1 (zh) * | 2013-06-06 | 2017-07-21 | Anergis Sa | 用於治疗室内尘蟎过敏的连续重叠肽 |
| JP7007534B2 (ja) * | 2013-09-25 | 2022-01-24 | アラヴァックス ピーティーワイ リミテッド | 新規免疫療法組成物およびその使用 |
| AU2014369866A1 (en) | 2013-12-23 | 2016-06-30 | Alk-Abello A/S | Peptide combinations and uses thereof in treating dust mite allergy |
| US9920101B2 (en) | 2014-03-31 | 2018-03-20 | Boehringer Ingelheim Vetmedica Gmbh | Modular antigen transportation molecules and uses therof |
| WO2016037165A1 (en) | 2014-09-07 | 2016-03-10 | Selecta Biosciences, Inc. | Methods and compositions for attenuating exon skipping anti-viral transfer vector immune responses |
| US11452774B2 (en) | 2015-02-20 | 2022-09-27 | The Board Of Trustees Of The Leland Stanford Junior University | Mixed allergen compositions and methods for using the same |
| US10149904B2 (en) | 2015-02-20 | 2018-12-11 | The Board Of Trusteees Of The Leland Stanford Junior University | Mixed allergen compositions and methods for using the same |
| US10166286B2 (en) | 2015-02-20 | 2019-01-01 | The Board Of Trustees Of The Leland Stanford Junior University | Mixed allergen compositions and methods for using the same |
| US10143742B2 (en) | 2015-02-20 | 2018-12-04 | The Board Of Trustees Of The Leland Stanford Junior University | Mixed allergen compositions and methods for using the same |
| JPWO2016159181A1 (ja) * | 2015-03-30 | 2018-02-22 | 国立大学法人大阪大学 | 免疫用ペプチド、免疫用ペプチドの製造方法、それを含む免疫疾患用医薬組成物、および免疫疾患の治療方法 |
| KR20180061338A (ko) * | 2015-09-30 | 2018-06-07 | 베링거잉겔하임베트메디카게엠베하 | 동물에서의 개선된 모듈러 항원 수송 분자 및 이의 용도 |
| KR101858840B1 (ko) | 2016-01-15 | 2018-05-16 | 단국대학교 천안캠퍼스 산학협력단 | 집먼지진드기 유래 알레르겐에 의한 과민반응 면역조절제 |
| CA3055936A1 (en) | 2017-03-11 | 2018-09-20 | Selecta Biosciences, Inc. | Methods and compositions related to combined treatment with anti-inflammatories and synthetic nanocarriers comprising an immunosuppressant |
| JP7300595B2 (ja) | 2017-07-18 | 2023-06-30 | ソシエテ・デ・プロデュイ・ネスレ・エス・アー | 混合アレルゲン組成物の製造方法 |
| RU2020111503A (ru) * | 2017-09-18 | 2021-10-20 | Сутро Биофарма, Инк. | Конъюгаты антитела к рецептору фолиевой кислоты альфа и их применение |
| CN108078891B (zh) * | 2017-12-28 | 2021-05-07 | 昆明赛诺制药股份有限公司 | 一种含美洲大蠊精提物的保湿修复洗面奶 |
| CN107970199B (zh) * | 2018-01-03 | 2021-05-07 | 昆明赛诺制药股份有限公司 | 一种含美洲大蠊精提物的牙膏 |
| BR112021014486A2 (pt) | 2019-01-23 | 2021-09-28 | Before Brands, Inc. | Métodos para preparar composições de alérgenos mistas |
| CN117362453B (zh) * | 2023-12-08 | 2024-02-27 | 山东硕景生物科技有限公司 | 一种Derf1重组抗原、其制备方法及应用 |
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| US5126399A (en) * | 1986-04-30 | 1992-06-30 | Board Of Regents, The University Of Texas System | Methods and compositions for the preparation and use of site-directed immunologic reagents |
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