DK478186A - Praeparat indeholdende et salt af metoprolol og med kontrolleret afgivelse af dette salt - Google Patents
Praeparat indeholdende et salt af metoprolol og med kontrolleret afgivelse af dette salt Download PDFInfo
- Publication number
- DK478186A DK478186A DK478186A DK478186A DK478186A DK 478186 A DK478186 A DK 478186A DK 478186 A DK478186 A DK 478186A DK 478186 A DK478186 A DK 478186A DK 478186 A DK478186 A DK 478186A
- Authority
- DK
- Denmark
- Prior art keywords
- salt
- metoprolol
- preparation containing
- controlled delivery
- beads
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Management, Administration, Business Operations System, And Electronic Commerce (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8504721 | 1985-10-11 | ||
SE8504721A SE455836B (sv) | 1985-10-11 | 1985-10-11 | Beredning med kontrollerad frisettning innehallande ett salt av metoprolol samt metod for framstellning av denna beredning |
Publications (4)
Publication Number | Publication Date |
---|---|
DK478186D0 DK478186D0 (da) | 1986-10-07 |
DK478186A true DK478186A (da) | 1987-04-12 |
DK165939B DK165939B (da) | 1993-02-15 |
DK165939C DK165939C (da) | 1993-07-05 |
Family
ID=20361706
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK478186A DK165939C (da) | 1985-10-11 | 1986-10-07 | Metropololpraeparat med styret, kontinuerlig afgivelse af det aktive stof, farmaceutisk praeparat indeholdende samme og fremgangsmaade til fremstilling af metropololpraeparatet samt anvendelse af metropololpraeparatet til fremstilling af et farmaceutisk praeparat til behandling af kardiovaskulaere lidelser |
Country Status (33)
Country | Link |
---|---|
US (1) | US4957745A (da) |
EP (1) | EP0220143B1 (da) |
JP (1) | JPH0759506B2 (da) |
KR (1) | KR940000100B1 (da) |
CN (1) | CN1023293C (da) |
AT (1) | ATE65391T1 (da) |
AU (1) | AU588630B2 (da) |
CY (1) | CY1616A (da) |
DD (1) | DD259789A5 (da) |
DE (2) | DE3680450D1 (da) |
DK (1) | DK165939C (da) |
DZ (1) | DZ994A1 (da) |
ES (1) | ES2003863B3 (da) |
FI (1) | FI88579C (da) |
GB (1) | GB2181348B (da) |
GR (2) | GR890300059T1 (da) |
HK (1) | HK101791A (da) |
HU (1) | HU197839B (da) |
IE (1) | IE59053B1 (da) |
IS (1) | IS1529B (da) |
LT (2) | LTIP1680A (da) |
LV (3) | LV10913B (da) |
NO (1) | NO172276C (da) |
NZ (1) | NZ217696A (da) |
PH (1) | PH22277A (da) |
PL (1) | PL261802A1 (da) |
PT (1) | PT83509B (da) |
RU (1) | RU2072840C1 (da) |
SE (1) | SE455836B (da) |
SG (1) | SG95291G (da) |
SU (1) | SU1760969A3 (da) |
UA (2) | UA26211A (da) |
ZA (1) | ZA869860B (da) |
Families Citing this family (61)
Publication number | Priority date | Publication date | Assignee | Title |
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SE8703881D0 (sv) * | 1987-10-08 | 1987-10-08 | Haessle Ab | New pharmaceutical preparation |
US4892739A (en) * | 1988-04-25 | 1990-01-09 | Ciba-Geigy Corporation | Osmotic continuous dispensing oral delivery system containing a pharmaceutically acceptable active agent having a improved core membrane adhesion properties |
US5268182A (en) * | 1988-06-24 | 1993-12-07 | Abbott Laboratories | Sustained-release drug dosage units of terazosin |
US5612059A (en) * | 1988-08-30 | 1997-03-18 | Pfizer Inc. | Use of asymmetric membranes in delivery devices |
US5084287A (en) * | 1990-03-15 | 1992-01-28 | Warner-Lambert Company | Pharmaceutically useful micropellets with a drug-coated core and controlled-release polymeric coat |
EP0542926B1 (en) * | 1990-08-07 | 1995-02-15 | Pfizer Inc. | Use of interfacially-polymerized membranes in delivery devices |
AU660984B2 (en) * | 1991-03-18 | 1995-07-13 | Sepracor, Inc. | Composition and method containing optically pure (S) metoprolol |
ES2073301T3 (es) * | 1991-05-20 | 1995-08-01 | Marion Laboratories Inc | Composicion multi-capa de liberacion controlada. |
IT1252185B (it) * | 1991-12-11 | 1995-06-05 | Therapicon Srl | Preparazioni farmaceutiche a liberazione programmata |
US7740881B1 (en) | 1993-07-01 | 2010-06-22 | Purdue Pharma Lp | Method of treating humans with opioid formulations having extended controlled release |
US5399358A (en) * | 1993-11-12 | 1995-03-21 | Edward Mendell Co., Inc. | Sustained release formulations for 24 hour release of metroprolol |
US8071128B2 (en) | 1996-06-14 | 2011-12-06 | Kyowa Hakko Kirin Co., Ltd. | Intrabuccally rapidly disintegrating tablet and a production method of the tablets |
SE9702338D0 (sv) * | 1997-06-18 | 1997-06-18 | Astra Ab | An analytical method and industrial process including the same |
SE9802537D0 (sv) * | 1998-07-13 | 1998-07-13 | Astra Ab | Method for controlling a coating process |
EP1117384A1 (en) * | 1998-10-01 | 2001-07-25 | Elan Pharma International Limited | Controlled release nanoparticulate compositions |
US8236352B2 (en) | 1998-10-01 | 2012-08-07 | Alkermes Pharma Ireland Limited | Glipizide compositions |
US8293277B2 (en) | 1998-10-01 | 2012-10-23 | Alkermes Pharma Ireland Limited | Controlled-release nanoparticulate compositions |
DE19848651C1 (de) * | 1998-10-22 | 2000-01-27 | Porsche Ag | Tülle für ein Kabelbündel |
ES2197600T3 (es) | 1999-01-29 | 2004-01-01 | Disphar International B.V. | Composiciones farmaceuticas. |
FR2802424B1 (fr) * | 1999-12-17 | 2002-02-15 | Adir | Comprime matriciel permettant la liberation prolongee de trimetazidine apres administration par voie orale |
US7198795B2 (en) | 2000-09-21 | 2007-04-03 | Elan Pharma International Ltd. | In vitro methods for evaluating the in vivo effectiveness of dosage forms of microparticulate of nanoparticulate active agent compositions |
GB0025208D0 (en) | 2000-10-13 | 2000-11-29 | Euro Celtique Sa | Delayed release pharmaceutical formulations |
SE0100200D0 (sv) * | 2001-01-24 | 2001-01-24 | Astrazeneca Ab | New film coating |
US20040105886A1 (en) * | 2001-02-16 | 2004-06-03 | Chih-Ming Chen | Divalproex sodium tablets |
US6610326B2 (en) | 2001-02-16 | 2003-08-26 | Andrx Corporation | Divalproex sodium tablets |
SE0100824D0 (sv) * | 2001-03-09 | 2001-03-09 | Astrazeneca Ab | Method III to obtain microparticles |
US9358214B2 (en) | 2001-10-04 | 2016-06-07 | Adare Pharmaceuticals, Inc. | Timed, sustained release systems for propranolol |
CA2435729C (en) * | 2001-12-19 | 2005-12-13 | Astrazeneca Ab | New film coating |
PT1471887E (pt) | 2002-02-04 | 2010-07-16 | Elan Pharma Int Ltd | Composiães de nanopartculas com lisozima como um estabilizador superficial |
EP1499295A4 (en) * | 2002-04-05 | 2006-04-05 | Penwest Pharmaceuticals Co | EXTENDED RELEASE METOPROLOL FORMULATIONS |
SE0201110D0 (sv) * | 2002-04-12 | 2002-04-12 | Astrazeneca Ab | New film coating |
US8367111B2 (en) | 2002-12-31 | 2013-02-05 | Aptalis Pharmatech, Inc. | Extended release dosage forms of propranolol hydrochloride |
US7217300B2 (en) | 2003-06-27 | 2007-05-15 | Delphi Technologies, Inc. | Method and apparatus for gasketing a fuel cell |
US7314640B2 (en) * | 2003-07-11 | 2008-01-01 | Mongkol Sriwongjanya | Formulation and process for drug loaded cores |
US20050032879A1 (en) * | 2003-08-07 | 2005-02-10 | Temple Okarter | Formulations and use of a beta-blocker and an ACE-inhibitor for the treatment of cardiovascular diseases |
MXPA06009054A (es) * | 2004-02-11 | 2007-04-16 | Athpharma Ltd | Composiciones cronoterapeuticas y metodos de su uso. |
US20060105044A1 (en) | 2004-05-20 | 2006-05-18 | Singh Bramah N | Sustained release formulations of sotalol |
US8747895B2 (en) | 2004-09-13 | 2014-06-10 | Aptalis Pharmatech, Inc. | Orally disintegrating tablets of atomoxetine |
US9884014B2 (en) | 2004-10-12 | 2018-02-06 | Adare Pharmaceuticals, Inc. | Taste-masked pharmaceutical compositions |
NZ589750A (en) | 2004-10-21 | 2012-07-27 | Aptalis Pharmatech Inc | Taste-masked pharmaceutical compositions with gastrosoluble pore-formers |
US9161918B2 (en) | 2005-05-02 | 2015-10-20 | Adare Pharmaceuticals, Inc. | Timed, pulsatile release systems |
EP1898886B1 (en) | 2005-07-01 | 2019-09-04 | Rubicon Research Pvt Ltd. | Novel sustained release dosage form |
US20070009589A1 (en) * | 2005-07-07 | 2007-01-11 | Kandarapu Raghupathi | Extended release compositions |
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US20070053983A1 (en) * | 2005-09-06 | 2007-03-08 | Girish Jain | Extended release compositions of metoprolol succinate |
US20070092573A1 (en) * | 2005-10-24 | 2007-04-26 | Laxminarayan Joshi | Stabilized extended release pharmaceutical compositions comprising a beta-adrenoreceptor antagonist |
DE102005060393A1 (de) | 2005-12-16 | 2007-06-21 | Add Advanced Drug Delivery Technologies Ltd. | Orales Präparat mit kontrollierter Freisetzung |
US8691272B2 (en) * | 2005-12-30 | 2014-04-08 | Intelgenx Corp. | Multilayer tablet |
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NZ574427A (en) * | 2006-07-28 | 2011-11-25 | Zaklady Farmaceutyczne Polpharma S A | Extended release pharmaceutical formulation of metoprolol and process for its preparation |
US20080107726A1 (en) * | 2006-11-01 | 2008-05-08 | Pramod Kharwade | Compositions comprising beta-adrenergic receptor antagonists and diuretics |
US20080187579A1 (en) * | 2007-02-01 | 2008-08-07 | Pavan Bhat | Extended-release dosage form |
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ATE533475T1 (de) * | 2009-04-03 | 2011-12-15 | Zaklady Farmaceutyczne Polpharma Sa | Pharmazeutische zusammensetzung mit verlängerter freisetzung mit metoprololsuccinat |
ES2668203T3 (es) | 2009-12-02 | 2018-05-17 | Adare Pharmaceuticals S.R.L. | Microcápsulas de fexofenadina y composiciones que las contienen |
US20110136815A1 (en) | 2009-12-08 | 2011-06-09 | Horst Zerbe | Solid oral film dosage forms and methods for making same |
US10610528B2 (en) | 2009-12-08 | 2020-04-07 | Intelgenx Corp. | Solid oral film dosage forms and methods for making same |
CN102670539A (zh) * | 2011-03-14 | 2012-09-19 | 北京天衡药物研究院 | 琥珀酸美托洛尔渗透泵控释片 |
CN105007902A (zh) | 2013-02-13 | 2015-10-28 | 赢创罗姆有限公司 | 包含大量的两种丸粒的多颗粒药物组合物 |
WO2014140867A2 (en) * | 2013-03-15 | 2014-09-18 | Cape Spear Pharmaceuticals, Ltd. | Compositions and methods for administration to subjects with dysphagia |
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PH18946A (en) * | 1983-04-21 | 1985-11-14 | Elan Corp Plc | Controlled absorption pharmaceutical composition |
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SE457505B (sv) * | 1984-01-10 | 1989-01-09 | Lejus Medical Ab | Laminatbelagd oral farmaceutisk komposition och foerfarande foer dess framstaellning |
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-
1985
- 1985-10-11 SE SE8504721A patent/SE455836B/sv not_active IP Right Cessation
-
1986
- 1986-09-09 ZA ZA869860A patent/ZA869860B/xx unknown
- 1986-09-18 IE IE249286A patent/IE59053B1/en not_active IP Right Cessation
- 1986-09-25 PH PH34289A patent/PH22277A/en unknown
- 1986-09-25 GB GB8623048A patent/GB2181348B/en not_active Expired
- 1986-09-26 NZ NZ217696A patent/NZ217696A/xx unknown
- 1986-09-26 AU AU63171/86A patent/AU588630B2/en not_active Expired
- 1986-10-02 AT AT86850330T patent/ATE65391T1/de not_active IP Right Cessation
- 1986-10-02 EP EP86850330A patent/EP0220143B1/en not_active Expired - Lifetime
- 1986-10-02 ES ES86850330T patent/ES2003863B3/es not_active Expired - Lifetime
- 1986-10-02 DE DE8686850330T patent/DE3680450D1/de not_active Expired - Lifetime
- 1986-10-02 DE DE198686850330T patent/DE220143T1/de active Pending
- 1986-10-07 DK DK478186A patent/DK165939C/da not_active IP Right Cessation
- 1986-10-07 NO NO863997A patent/NO172276C/no unknown
- 1986-10-08 DZ DZ860208A patent/DZ994A1/fr active
- 1986-10-09 JP JP61239424A patent/JPH0759506B2/ja not_active Expired - Lifetime
- 1986-10-09 PT PT83509A patent/PT83509B/pt unknown
- 1986-10-10 PL PL1986261802A patent/PL261802A1/xx unknown
- 1986-10-10 DD DD86295170A patent/DD259789A5/de unknown
- 1986-10-10 HU HU864249A patent/HU197839B/hu unknown
- 1986-10-10 IS IS3151A patent/IS1529B/is unknown
- 1986-10-10 FI FI864108A patent/FI88579C/fi not_active IP Right Cessation
- 1986-10-10 SU SU864028342A patent/SU1760969A3/ru active
- 1986-10-10 UA UA4028342A patent/UA26211A/uk unknown
- 1986-10-10 KR KR1019860008481A patent/KR940000100B1/ko not_active IP Right Cessation
- 1986-10-11 CN CN86106588A patent/CN1023293C/zh not_active Expired - Lifetime
-
1989
- 1989-02-14 US US07/310,489 patent/US4957745A/en not_active Expired - Lifetime
- 1989-06-22 GR GR89300059T patent/GR890300059T1/el unknown
-
1991
- 1991-08-19 GR GR91401214T patent/GR3002571T3/el unknown
- 1991-09-10 RU SU915001493A patent/RU2072840C1/ru active
- 1991-09-10 UA UA5001493A patent/UA39162C2/uk unknown
- 1991-11-08 SG SG952/91A patent/SG95291G/en unknown
- 1991-12-12 HK HK1017/91A patent/HK101791A/xx not_active IP Right Cessation
-
1992
- 1992-07-10 CY CY1616A patent/CY1616A/xx unknown
-
1993
- 1993-06-28 LV LVP-93-685A patent/LV10913B/en unknown
- 1993-06-30 LV LV930884A patent/LV10914A/xx unknown
- 1993-12-28 LT LTIP1680A patent/LTIP1680A/xx not_active Application Discontinuation
- 1993-12-28 LT LTIP1679A patent/LT3951B/lt not_active IP Right Cessation
-
1996
- 1996-07-17 LV LV960258A patent/LV5751B4/xx unknown
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Legal Events
Date | Code | Title | Description |
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PUP | Patent expired |