DK3221457T3 - Fremgangsmåder og sammensætninger til targeteret genomisk modifikation ved anvendelse af parrede førings-rnaer - Google Patents

Fremgangsmåder og sammensætninger til targeteret genomisk modifikation ved anvendelse af parrede førings-rnaer Download PDF

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DK3221457T3
DK3221457T3 DK15804289.5T DK15804289T DK3221457T3 DK 3221457 T3 DK3221457 T3 DK 3221457T3 DK 15804289 T DK15804289 T DK 15804289T DK 3221457 T3 DK3221457 T3 DK 3221457T3
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rnaer
parented
route
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methods
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DK15804289.5T
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Andrew J Murphy
David Frendewey
Ka-Man Venus Lai
Wojtek Auerbach
Gustavo Droguett
Anthony Gagliardi
Vera Voronina
Lynn Macdonald
George D Yancopoulos
David M Valenzuela
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Regeneron Pharma
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    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
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    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPR]
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    • C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/16—Assays for determining copy number or wherein the copy number is of special importance

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DK15804289.5T 2014-11-21 2015-11-20 Fremgangsmåder og sammensætninger til targeteret genomisk modifikation ved anvendelse af parrede førings-rnaer DK3221457T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201462083005P 2014-11-21 2014-11-21
US201562182314P 2015-06-19 2015-06-19
US201562211421P 2015-08-28 2015-08-28
PCT/US2015/062023 WO2016081923A2 (en) 2014-11-21 2015-11-20 METHODS AND COMPOSITIONS FOR TARGETED GENETIC MODIFICATION USING PAIRED GUIDE RNAs

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DK3221457T3 true DK3221457T3 (da) 2019-06-03

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US (4) US10457960B2 (enExample)
EP (2) EP3221457B1 (enExample)
JP (2) JP6727199B2 (enExample)
KR (3) KR102531016B1 (enExample)
CN (2) CN107208078B (enExample)
AU (2) AU2015349692B2 (enExample)
BR (1) BR112017010547A2 (enExample)
CA (2) CA2968440A1 (enExample)
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DK (1) DK3221457T3 (enExample)
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HR (1) HRP20190949T1 (enExample)
HU (1) HUE044907T2 (enExample)
IL (3) IL283585B2 (enExample)
LT (1) LT3221457T (enExample)
MX (2) MX389266B (enExample)
NZ (1) NZ731962A (enExample)
PL (1) PL3221457T3 (enExample)
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RS (1) RS58893B1 (enExample)
RU (2) RU2020134412A (enExample)
SG (2) SG10201913829YA (enExample)
SI (1) SI3221457T1 (enExample)
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