JP6727199B2 - ガイドｒｎａのペアを使用したターゲティングによる遺伝子改変の方法及び組成物 - Google Patents

ガイドｒｎａのペアを使用したターゲティングによる遺伝子改変の方法及び組成物 Download PDF

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JP6727199B2
JP6727199B2 JP2017527267A JP2017527267A JP6727199B2 JP 6727199 B2 JP6727199 B2 JP 6727199B2 JP 2017527267 A JP2017527267 A JP 2017527267A JP 2017527267 A JP2017527267 A JP 2017527267A JP 6727199 B2 JP6727199 B2 JP 6727199B2
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crispr rna
sequence
nucleic acid
rna recognition
cells
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JP2017535271A5 (enExample
JP2017535271A (ja
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アンドリュー ジェイ． マーフィー，
アンドリュー ジェイ． マーフィー，
デイビッド フレンドウェイ，
デイビッド フレンドウェイ，
カ−マン ビーナス ライ，
カ−マン ビーナス ライ，
ボイテック オーバッハ，
ボイテック オーバッハ，
グスターボ ドロゲット，
グスターボ ドロゲット，
アンソニー ガグリアルディ，
アンソニー ガグリアルディ，
デイビッド エム． バレンズエラ，
デイビッド エム． バレンズエラ，
ベラ ボロニナ，
ベラ ボロニナ，
リン マクドナルド，
リン マクドナルド，
ジョージ ディー． ヤンコポーロス，
ジョージ ディー． ヤンコポーロス，
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Regeneron Pharmaceuticals Inc
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Regeneron Pharmaceuticals Inc
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JP2017527267A 2014-11-21 2015-11-20 ガイドｒｎａのペアを使用したターゲティングによる遺伝子改変の方法及び組成物 Active JP6727199B2 (ja)

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Application Number Priority Date Filing Date Title
US201462083005P 2014-11-21 2014-11-21
US62/083,005 2014-11-21
US201562182314P 2015-06-19 2015-06-19
US62/182,314 2015-06-19
US201562211421P 2015-08-28 2015-08-28
US62/211,421 2015-08-28
PCT/US2015/062023 WO2016081923A2 (en) 2014-11-21 2015-11-20 METHODS AND COMPOSITIONS FOR TARGETED GENETIC MODIFICATION USING PAIRED GUIDE RNAs

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