DK3390632T3 - Fremgangsmåder og sammensætninger til polymerase ii (pol-ii)-baseret guide-rna-ekspression - Google Patents
Fremgangsmåder og sammensætninger til polymerase ii (pol-ii)-baseret guide-rna-ekspressionInfo
- Publication number
- DK3390632T3 DK3390632T3 DK16825944.8T DK16825944T DK3390632T3 DK 3390632 T3 DK3390632 T3 DK 3390632T3 DK 16825944 T DK16825944 T DK 16825944T DK 3390632 T3 DK3390632 T3 DK 3390632T3
- Authority
- DK
- Denmark
- Prior art keywords
- pol
- polymerase
- compositions
- methods
- guide rna
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/111—General methods applicable to biologically active non-coding nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/35—Nature of the modification
- C12N2310/351—Conjugate
- C12N2310/3519—Fusion with another nucleic acid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2330/00—Production
- C12N2330/50—Biochemical production, i.e. in a transformed host cell
- C12N2330/51—Specially adapted vectors
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Mycology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562269122P | 2015-12-18 | 2015-12-18 | |
| PCT/US2016/066772 WO2017106414A1 (en) | 2015-12-18 | 2016-12-15 | Methods and compositions for polymerase ii (pol-ii) based guide rna expression |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3390632T3 true DK3390632T3 (da) | 2025-12-01 |
Family
ID=57794349
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16825944.8T DK3390632T3 (da) | 2015-12-18 | 2016-12-15 | Fremgangsmåder og sammensætninger til polymerase ii (pol-ii)-baseret guide-rna-ekspression |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20200263165A1 (da) |
| EP (1) | EP3390632B1 (da) |
| JP (2) | JP2018537106A (da) |
| KR (1) | KR102698595B1 (da) |
| AU (1) | AU2016370726B2 (da) |
| CA (1) | CA3008010A1 (da) |
| DK (1) | DK3390632T3 (da) |
| FI (1) | FI3390632T3 (da) |
| MX (1) | MX2018007290A (da) |
| WO (1) | WO2017106414A1 (da) |
Families Citing this family (81)
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| WO2015048707A2 (en) * | 2013-09-30 | 2015-04-02 | Regents Of The University Of Minnesota | Conferring resistance to geminiviruses in plants using crispr/cas systems |
| EP3090044B1 (en) | 2013-12-26 | 2021-11-03 | The General Hospital Corporation | Multiplex guide rnas |
| US20170088845A1 (en) * | 2014-03-14 | 2017-03-30 | The Regents Of The University Of California | Vectors and methods for fungal genome engineering by crispr-cas9 |
| JP2017509350A (ja) * | 2014-04-03 | 2017-04-06 | マサチューセッツ インスティテュート オブ テクノロジー | ガイドrnaの生成のための方法および組成物 |
| WO2016110511A1 (en) * | 2015-01-06 | 2016-07-14 | Dsm Ip Assets B.V. | A crispr-cas system for a lipolytic yeast host cell |
-
2016
- 2016-12-15 DK DK16825944.8T patent/DK3390632T3/da active
- 2016-12-15 EP EP16825944.8A patent/EP3390632B1/en active Active
- 2016-12-15 FI FIEP16825944.8T patent/FI3390632T3/fi active
- 2016-12-15 WO PCT/US2016/066772 patent/WO2017106414A1/en not_active Ceased
- 2016-12-15 AU AU2016370726A patent/AU2016370726B2/en active Active
- 2016-12-15 KR KR1020187015753A patent/KR102698595B1/ko active Active
- 2016-12-15 US US16/061,521 patent/US20200263165A1/en not_active Abandoned
- 2016-12-15 CA CA3008010A patent/CA3008010A1/en active Pending
- 2016-12-15 JP JP2018530731A patent/JP2018537106A/ja active Pending
- 2016-12-15 MX MX2018007290A patent/MX2018007290A/es unknown
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2020
- 2020-12-28 JP JP2020219041A patent/JP7160891B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2018537106A (ja) | 2018-12-20 |
| WO2017106414A1 (en) | 2017-06-22 |
| FI3390632T3 (fi) | 2025-11-25 |
| JP2021058209A (ja) | 2021-04-15 |
| EP3390632A1 (en) | 2018-10-24 |
| KR20180086430A (ko) | 2018-07-31 |
| CA3008010A1 (en) | 2017-06-22 |
| EP3390632B1 (en) | 2025-09-10 |
| AU2016370726A1 (en) | 2018-05-10 |
| KR102698595B1 (ko) | 2024-08-23 |
| AU2016370726B2 (en) | 2022-12-08 |
| JP7160891B2 (ja) | 2022-10-25 |
| MX2018007290A (es) | 2019-01-10 |
| US20200263165A1 (en) | 2020-08-20 |
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