DK2835131T3 - Casein kinase 1 delta inhibitors (CK1 delta) - Google Patents

Casein kinase 1 delta inhibitors (CK1 delta) Download PDF

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Publication number
DK2835131T3
DK2835131T3 DK14190691.7T DK14190691T DK2835131T3 DK 2835131 T3 DK2835131 T3 DK 2835131T3 DK 14190691 T DK14190691 T DK 14190691T DK 2835131 T3 DK2835131 T3 DK 2835131T3
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Prior art keywords
alkyl
compound
tau
disease
dementia
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DK14190691.7T
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Danish (da)
English (en)
Inventor
Joseph M Sheridan
Jonathan R Heal
William D O Hamilton
Ian Pike
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Electrophoretics Ltd
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Priority claimed from GBGB1021161.3A external-priority patent/GB201021161D0/en
Priority claimed from GBGB1109162.6A external-priority patent/GB201109162D0/en
Application filed by Electrophoretics Ltd filed Critical Electrophoretics Ltd
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Publication of DK2835131T3 publication Critical patent/DK2835131T3/en

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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
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