DK167117B1 - Aminoalkoholderivater og syreadditionssalte deraf samt en analogifremgangsmaade til deres fremstilling - Google Patents

Aminoalkoholderivater og syreadditionssalte deraf samt en analogifremgangsmaade til deres fremstilling Download PDF

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Publication number
DK167117B1
DK167117B1 DK439285A DK439285A DK167117B1 DK 167117 B1 DK167117 B1 DK 167117B1 DK 439285 A DK439285 A DK 439285A DK 439285 A DK439285 A DK 439285A DK 167117 B1 DK167117 B1 DK 167117B1
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Prior art keywords
compound
formula
irs
acid addition
methyl
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Application number
DK439285A
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Danish (da)
English (en)
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DK439285A (da
DK439285D0 (da
Inventor
Mitsuo Masaki
Haruhiko Shinozaki
Masaru Satoh
Naoya Moritoh
Koishi Hashimoto
Toshiro Kamishiro
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Nippon Chemiphar Co
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Application filed by Nippon Chemiphar Co filed Critical Nippon Chemiphar Co
Publication of DK439285D0 publication Critical patent/DK439285D0/da
Publication of DK439285A publication Critical patent/DK439285A/da
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Publication of DK167117B1 publication Critical patent/DK167117B1/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK439285A 1984-09-28 1985-09-27 Aminoalkoholderivater og syreadditionssalte deraf samt en analogifremgangsmaade til deres fremstilling DK167117B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP59203623A JPS6183147A (ja) 1984-09-28 1984-09-28 新規なアミノアルコール誘導体およびその製造法並びにそれを有効成分とするグルタミン酸遮断剤
JP20362384 1984-09-28

Publications (3)

Publication Number Publication Date
DK439285D0 DK439285D0 (da) 1985-09-27
DK439285A DK439285A (da) 1986-03-29
DK167117B1 true DK167117B1 (da) 1993-08-30

Family

ID=16477107

Family Applications (1)

Application Number Title Priority Date Filing Date
DK439285A DK167117B1 (da) 1984-09-28 1985-09-27 Aminoalkoholderivater og syreadditionssalte deraf samt en analogifremgangsmaade til deres fremstilling

Country Status (21)

Country Link
EP (1) EP0177245B1 (ru)
JP (1) JPS6183147A (ru)
KR (1) KR910002671B1 (ru)
AR (1) AR242776A1 (ru)
AT (1) ATE62480T1 (ru)
AU (1) AU578737B2 (ru)
BR (1) BR8504879A (ru)
CA (1) CA1260467A (ru)
CS (1) CS264332B2 (ru)
DE (1) DE3582466D1 (ru)
DK (1) DK167117B1 (ru)
ES (1) ES8706610A1 (ru)
HU (1) HU199774B (ru)
IN (1) IN162767B (ru)
MX (1) MX162733A (ru)
MY (1) MY102921A (ru)
NZ (1) NZ213628A (ru)
PH (1) PH21169A (ru)
RO (1) RO93388B (ru)
SU (1) SU1433409A3 (ru)
ZA (1) ZA857449B (ru)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5070196A (en) * 1986-02-01 1991-12-03 Nippon Chemiphar Co., Ltd. Alkylenediamine derivatives
DE3789395T2 (de) * 1986-02-01 1994-08-04 Nippon Chemiphar Co Alkylendiamin-Derivate.
JPH0314562A (ja) * 1988-04-11 1991-01-23 Nippon Chemiphar Co Ltd 新規なアルキレンジアミン誘導体およびグルタミン酸遮断剤
AU2159692A (en) * 1991-06-06 1993-01-12 G.D. Searle & Co. N-(arylethyl)-n-alkyl-2-(1-pyrrolidinyl)ethylamine derivatives for cns disorders
IT1271623B (it) * 1994-03-21 1997-06-04 Lifegroup Spa N-acilderivati di aminoalcoli con acidi monocarbossilici e bicarbossilici con attivita' neuroprotettiva nelle patologie neurologiche correlate ad eccitotossicita'
CA2231013A1 (en) * 1997-04-30 1998-10-30 Eli Lilly And Company Process for preparing benzoic acid derivative intermediates and benzothiophene pharmaceuticals
DE10251170A1 (de) * 2002-10-31 2004-05-13 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
US20040127733A1 (en) 2002-10-31 2004-07-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg New beta-agonists, processes for preparing them and their use as pharmaceutical compositions
DE102004021779A1 (de) 2004-04-30 2005-11-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
DE102005052127A1 (de) 2005-10-28 2007-05-03 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue indol-haltige Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2600217A (en) * 1948-06-22 1952-06-10 American Cyanamid Co Diaryl-hydroxyalkyl-diamino compounds and preparation thereof
US3092636A (en) * 1959-10-21 1963-06-04 Upjohn Co Alpha-[2-(1-alkyleneimino) ethylamino]-alkanophenones and the corresponding alcohols
GB1200886A (en) * 1966-09-23 1970-08-05 Allen & Hanburys Ltd Phenylaminoethanol derivatives
US3517000A (en) * 1968-08-08 1970-06-23 American Home Prod Alpha-aminomethyl benzyl alcohols
FR2370472A2 (fr) * 1976-11-10 1978-06-09 Continental Pharma Amino-alcool heterocyclique, son sel et son procede de preparation
JPS6183170A (ja) * 1984-09-28 1986-04-26 Nippon Chemiphar Co Ltd 新規な1,3−オキサゾリジン−2−オン誘導体およびその製造法

Also Published As

Publication number Publication date
ZA857449B (en) 1986-06-25
MX162733A (es) 1991-06-24
CS264332B2 (en) 1989-07-12
ES8706610A1 (es) 1987-07-01
ES547283A0 (es) 1987-07-01
CS690485A2 (en) 1988-11-15
JPS6183147A (ja) 1986-04-26
EP0177245A3 (en) 1987-07-01
EP0177245A2 (en) 1986-04-09
KR860002450A (ko) 1986-04-26
SU1433409A3 (ru) 1988-10-23
AU4768985A (en) 1986-04-10
PH21169A (en) 1987-08-07
BR8504879A (pt) 1986-07-22
AU578737B2 (en) 1988-11-03
ATE62480T1 (de) 1991-04-15
DK439285A (da) 1986-03-29
HU199774B (en) 1990-03-28
EP0177245B1 (en) 1991-04-10
CA1260467A (en) 1989-09-26
MY102921A (en) 1993-03-31
AR242776A1 (es) 1993-05-31
RO93388B (ro) 1988-01-03
NZ213628A (en) 1989-03-29
JPH0517900B2 (ru) 1993-03-10
KR910002671B1 (ko) 1991-05-03
RO93388A (ro) 1987-12-31
IN162767B (ru) 1988-07-09
DK439285D0 (da) 1985-09-27
HUT40613A (en) 1987-01-28
DE3582466D1 (de) 1991-05-16

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed