DK1578936T3 - Humane anti-IFN-gamma-neutraliserende antistoffer som selektive inhibitorer af IFN-gamma-vejen - Google Patents
Humane anti-IFN-gamma-neutraliserende antistoffer som selektive inhibitorer af IFN-gamma-vejenInfo
- Publication number
- DK1578936T3 DK1578936T3 DK03777635.8T DK03777635T DK1578936T3 DK 1578936 T3 DK1578936 T3 DK 1578936T3 DK 03777635 T DK03777635 T DK 03777635T DK 1578936 T3 DK1578936 T3 DK 1578936T3
- Authority
- DK
- Denmark
- Prior art keywords
- ifn
- gamma
- neutralizing antibodies
- human anti
- selective inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/249—Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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-
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Physical Education & Sports Medicine (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Neurology (AREA)
- Reproductive Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Gynecology & Obstetrics (AREA)
- Neurosurgery (AREA)
- Transplantation (AREA)
- Obesity (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41905702P | 2002-10-16 | 2002-10-16 | |
| US47924103P | 2003-06-17 | 2003-06-17 | |
| PCT/US2003/032871 WO2004035747A2 (en) | 2002-10-16 | 2003-10-16 | Human anti-ifn-ϝ neutralizing antibodies as selective ifn-ϝ pathway inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1578936T3 true DK1578936T3 (da) | 2011-12-05 |
Family
ID=32110210
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03777635.8T DK1578936T3 (da) | 2002-10-16 | 2003-10-16 | Humane anti-IFN-gamma-neutraliserende antistoffer som selektive inhibitorer af IFN-gamma-vejen |
Country Status (27)
| Country | Link |
|---|---|
| US (5) | US7335743B2 (da) |
| EP (2) | EP2298811B8 (da) |
| JP (2) | JP4252061B2 (da) |
| KR (1) | KR100816124B1 (da) |
| CN (1) | CN1820026B (da) |
| AT (1) | ATE520416T1 (da) |
| AU (2) | AU2003285874A1 (da) |
| BR (1) | BR0315161A (da) |
| CA (1) | CA2501653C (da) |
| CY (1) | CY1111812T1 (da) |
| DK (1) | DK1578936T3 (da) |
| EA (1) | EA011876B1 (da) |
| EG (1) | EG26731A (da) |
| ES (1) | ES2370473T3 (da) |
| HK (1) | HK1084689A1 (da) |
| IL (1) | IL167436A (da) |
| ME (2) | MEP30308A (da) |
| MX (1) | MXPA05003907A (da) |
| NO (1) | NO336802B1 (da) |
| NZ (1) | NZ538893A (da) |
| PL (1) | PL377338A1 (da) |
| PT (1) | PT1578936E (da) |
| RS (1) | RS52690B (da) |
| SG (1) | SG155054A1 (da) |
| SI (1) | SI1578936T1 (da) |
| WO (2) | WO2004034988A2 (da) |
| ZA (1) | ZA200503821B (da) |
Families Citing this family (124)
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|---|---|---|---|---|
| AU2003285874A1 (en) | 2002-10-16 | 2004-05-04 | Amgen Inc. | HUMAN ANTI-IFN-Gamma NEUTRALIZING ANTIBODIES AS SELECTIVE IFN-Gamma PATHWAY INHIBITORS |
| EA013118B1 (ru) | 2005-01-27 | 2010-02-26 | Новиммун С.А. | Антитела против интерферона-гамма и способы их применения |
| CA2607663C (en) * | 2005-05-19 | 2014-08-12 | Amgen Inc. | Compositions and methods for increasing the stability of antibodies |
| EA012801B1 (ru) | 2005-06-14 | 2009-12-30 | Эмджен Инк. | Самобуферирующиеся композиции белков |
| GB0704038D0 (en) * | 2007-03-02 | 2007-04-11 | Deepstream Technologies Ltd | Nulling current transformer |
| EP2197421A1 (en) * | 2007-08-31 | 2010-06-23 | Amgen, Inc | Solid-state protein formulation |
| ES2750254T3 (es) | 2007-09-27 | 2020-03-25 | Amgen Inc | Formulaciones farmacéuticas |
| EP3381445B1 (en) | 2007-11-15 | 2023-10-25 | Amgen Inc. | Aqueous formulation of antibody stablised by antioxidants for parenteral administration |
| WO2009134489A2 (en) * | 2008-02-01 | 2009-11-05 | Albany Medical College | Blockage of interferon-gamma for prevention of polymicrobial synergy |
| JP4954326B2 (ja) * | 2008-04-11 | 2012-06-13 | 中外製薬株式会社 | 複数分子の抗原に繰り返し結合する抗原結合分子 |
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| WO2011098518A2 (en) * | 2010-02-11 | 2011-08-18 | Ablynx Nv | Delivery of immunoglobulin variable domains and constructs thereof |
| ES2545411T5 (es) | 2010-06-07 | 2024-04-05 | Amgen Inc | Dispositivo de administración de fármaco |
| US20140093496A1 (en) | 2011-02-25 | 2014-04-03 | Chugai Seiyaku Kabushiki Kaisha | Fc-gamma-RIIb-SPECIFIC Fc ANTIBODY |
| US9480624B2 (en) | 2011-03-31 | 2016-11-01 | Amgen Inc. | Vial adapter and system |
| LT2699293T (lt) | 2011-04-20 | 2019-04-25 | Amgen Inc. | Automatinio purškimo prietaisas |
| KR102084171B1 (ko) | 2011-10-14 | 2020-04-14 | 암젠 인크 | 주사기 및 어셈블리 방법 |
| AU2012340624B2 (en) * | 2011-11-23 | 2017-08-24 | Amgen Inc. | Methods of treatment using an antibody against interferon gamma |
| UY35148A (es) | 2012-11-21 | 2014-05-30 | Amgen Inc | Immunoglobulinas heterodiméricas |
| SI3081249T1 (sl) | 2012-11-21 | 2021-03-31 | Amgen Inc. | Naprava za dajanje zdravila |
| US9708375B2 (en) | 2013-03-15 | 2017-07-18 | Amgen Inc. | Inhibitory polypeptides specific to WNT inhibitors |
| TWI639449B (zh) | 2013-03-15 | 2018-11-01 | 美商安美基公司 | 用於注射器之匣盒 |
| WO2014149357A1 (en) | 2013-03-22 | 2014-09-25 | Amgen Inc. | Injector and method of assembly |
| RU2539752C2 (ru) * | 2013-05-23 | 2015-01-27 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) | ГУМАНИЗИРОВАННОЕ АНТИТЕЛО И АНТИГЕНСВЯЗЫВАЮЩИЙ ФРАГМЕНТ (Fab), СВЯЗЫВАЮЩИЕСЯ С ИНТЕРФЕРОНОМ- γ ЧЕЛОВЕКА, ФРАГМЕНТЫ ДНК, КОДИРУЮЩИЕ УКАЗАННОЕ АНТИТЕЛО И АНТИГЕНСВЯЗЫВАЮЩИЙ ФРАГМЕНТ, КЛЕТКА, ТРАНСФОРМИРОВАННАЯ ФРАГМЕНТОМ ДНК, И СПОСОБ ПОЛУЧЕНИЯ УКАЗАННОГО АНТИТЕЛА И АНТИГЕНСВЯЗЫВАЮЩЕГО ФРАГМЕНТА |
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| JP6822843B2 (ja) | 2014-06-03 | 2021-01-27 | アムジエン・インコーポレーテツド | 薬物送達装置によって収集されたデータを遠隔で処理するためのシステム及び方法 |
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| KR102230549B1 (ko) | 2014-09-12 | 2021-03-22 | 삼성디스플레이 주식회사 | 접촉 감지 기능을 가진 광학계 및 이를 포함하는 표시 장치 |
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- 2003-10-16 ES ES03777635T patent/ES2370473T3/es not_active Expired - Lifetime
- 2003-10-16 ME MEP-2008-303A patent/ME00205B/me unknown
- 2003-10-16 PT PT03777635T patent/PT1578936E/pt unknown
- 2003-10-16 AT AT03777635T patent/ATE520416T1/de active
- 2003-10-16 MX MXPA05003907A patent/MXPA05003907A/es active IP Right Grant
- 2003-10-16 CA CA2501653A patent/CA2501653C/en not_active Expired - Fee Related
- 2003-10-16 CN CN2003801015432A patent/CN1820026B/zh not_active Expired - Fee Related
- 2003-10-16 WO PCT/US2003/032871 patent/WO2004035747A2/en active Search and Examination
- 2003-10-16 BR BR0315161-1A patent/BR0315161A/pt not_active Application Discontinuation
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2005
- 2005-03-15 IL IL167436A patent/IL167436A/en active IP Right Grant
- 2005-03-15 NO NO20051345A patent/NO336802B1/no not_active IP Right Cessation
- 2005-04-13 EG EGPCTNA2005000139A patent/EG26731A/en active
- 2005-05-12 ZA ZA200503821A patent/ZA200503821B/en unknown
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2006
- 2006-03-14 HK HK06103252.1A patent/HK1084689A1/xx not_active IP Right Cessation
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2007
- 2007-12-21 US US11/962,594 patent/US7790859B2/en not_active Expired - Lifetime
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2008
- 2008-10-14 JP JP2008265800A patent/JP2009082133A/ja active Pending
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2010
- 2010-07-06 US US12/831,087 patent/US8202976B2/en not_active Expired - Lifetime
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2011
- 2011-09-06 CY CY20111100852T patent/CY1111812T1/el unknown
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2012
- 2012-05-21 US US13/476,317 patent/US8529893B2/en not_active Expired - Lifetime
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2013
- 2013-08-13 US US13/966,185 patent/US8906371B2/en not_active Expired - Lifetime
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