DK1578936T3 - Humane anti-IFN-gamma-neutraliserende antistoffer som selektive inhibitorer af IFN-gamma-vejen - Google Patents

Humane anti-IFN-gamma-neutraliserende antistoffer som selektive inhibitorer af IFN-gamma-vejen

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Publication number
DK1578936T3
DK1578936T3 DK03777635.8T DK03777635T DK1578936T3 DK 1578936 T3 DK1578936 T3 DK 1578936T3 DK 03777635 T DK03777635 T DK 03777635T DK 1578936 T3 DK1578936 T3 DK 1578936T3
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DK
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Prior art keywords
ifn
gamma
neutralizing antibodies
human anti
selective inhibitors
Prior art date
Application number
DK03777635.8T
Other languages
English (en)
Inventor
Andrew A Welcher
Hilary T Chute
Yue-Sheng Li
Haichun Huang
Original Assignee
Amgen Inc
Medarex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc, Medarex Inc filed Critical Amgen Inc
Application granted granted Critical
Publication of DK1578936T3 publication Critical patent/DK1578936T3/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/249—Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P5/40—Mineralocorticosteroids, e.g. aldosterone; Drugs increasing or potentiating the activity of mineralocorticosteroids
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Endocrinology (AREA)
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  • Urology & Nephrology (AREA)
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  • Biomedical Technology (AREA)
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  • Tropical Medicine & Parasitology (AREA)
DK03777635.8T 2002-10-16 2003-10-16 Humane anti-IFN-gamma-neutraliserende antistoffer som selektive inhibitorer af IFN-gamma-vejen DK1578936T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41905702P 2002-10-16 2002-10-16
US47924103P 2003-06-17 2003-06-17
PCT/US2003/032871 WO2004035747A2 (en) 2002-10-16 2003-10-16 Human anti-ifn-ϝ neutralizing antibodies as selective ifn-ϝ pathway inhibitors

Publications (1)

Publication Number Publication Date
DK1578936T3 true DK1578936T3 (da) 2011-12-05

Family

ID=32110210

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DK03777635.8T DK1578936T3 (da) 2002-10-16 2003-10-16 Humane anti-IFN-gamma-neutraliserende antistoffer som selektive inhibitorer af IFN-gamma-vejen

Country Status (27)

Country Link
US (5) US7335743B2 (da)
EP (2) EP1578936B1 (da)
JP (2) JP4252061B2 (da)
KR (1) KR100816124B1 (da)
CN (1) CN1820026B (da)
AT (1) ATE520416T1 (da)
AU (2) AU2003285874A1 (da)
BR (1) BR0315161A (da)
CA (1) CA2501653C (da)
CY (1) CY1111812T1 (da)
DK (1) DK1578936T3 (da)
EA (1) EA011876B1 (da)
EG (1) EG26731A (da)
ES (1) ES2370473T3 (da)
HK (1) HK1084689A1 (da)
IL (1) IL167436A (da)
ME (2) MEP30308A (da)
MX (1) MXPA05003907A (da)
NO (1) NO336802B1 (da)
NZ (1) NZ538893A (da)
PL (1) PL377338A1 (da)
PT (1) PT1578936E (da)
RS (1) RS52690B (da)
SG (1) SG155054A1 (da)
SI (1) SI1578936T1 (da)
WO (2) WO2004034988A2 (da)
ZA (1) ZA200503821B (da)

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