IT1231727B - Peptidi utili per la determinazione e la purificazione di anticorpi anti gamma interferone. - Google Patents

Peptidi utili per la determinazione e la purificazione di anticorpi anti gamma interferone.

Info

Publication number
IT1231727B
IT1231727B IT8921517A IT2151789A IT1231727B IT 1231727 B IT1231727 B IT 1231727B IT 8921517 A IT8921517 A IT 8921517A IT 2151789 A IT2151789 A IT 2151789A IT 1231727 B IT1231727 B IT 1231727B
Authority
IT
Italy
Prior art keywords
interferone
antibodies
purification
determination
range
Prior art date
Application number
IT8921517A
Other languages
English (en)
Other versions
IT8921517A0 (it
Inventor
Enrico Savoldi
Original Assignee
Enrico Savoldi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Enrico Savoldi filed Critical Enrico Savoldi
Priority to IT8921517A priority Critical patent/IT1231727B/it
Publication of IT8921517A0 publication Critical patent/IT8921517A0/it
Priority to AT9090912151T priority patent/ATE104990T1/de
Priority to PCT/EP1990/001293 priority patent/WO1991002005A1/en
Priority to DE69008535T priority patent/DE69008535T2/de
Priority to EP90912151A priority patent/EP0485471B1/en
Priority to JP2511587A priority patent/JPH05500360A/ja
Priority to AU61766/90A priority patent/AU6176690A/en
Application granted granted Critical
Publication of IT1231727B publication Critical patent/IT1231727B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/249—Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/57—IFN-gamma
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Transplantation (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT8921517A 1989-08-11 1989-08-11 Peptidi utili per la determinazione e la purificazione di anticorpi anti gamma interferone. IT1231727B (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IT8921517A IT1231727B (it) 1989-08-11 1989-08-11 Peptidi utili per la determinazione e la purificazione di anticorpi anti gamma interferone.
AT9090912151T ATE104990T1 (de) 1989-08-11 1990-08-08 Humane antigammainterferonantikoerper, welche detektiert und geklaert sind mit verwendung von synthetischen peptiden.
PCT/EP1990/001293 WO1991002005A1 (en) 1989-08-11 1990-08-08 Natural human anti-gamma interferon antibodies detected and purified by synthetic peptides
DE69008535T DE69008535T2 (de) 1989-08-11 1990-08-08 Humane antigammainterferonantikörper, welche detektiert und geklärt sind mit verwendung von synthetischen peptiden.
EP90912151A EP0485471B1 (en) 1989-08-11 1990-08-08 Natural human anti-gamma interferon antibodies detected and purified by synthetic peptides
JP2511587A JPH05500360A (ja) 1989-08-11 1990-08-08 合成ペプチドによって検出、精製された天然ヒト抗ガンマインターフェロン抗体
AU61766/90A AU6176690A (en) 1989-08-11 1990-08-08 Natural human anti-gamma interferon antibodies detected and purified by synthetic peptides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8921517A IT1231727B (it) 1989-08-11 1989-08-11 Peptidi utili per la determinazione e la purificazione di anticorpi anti gamma interferone.

Publications (2)

Publication Number Publication Date
IT8921517A0 IT8921517A0 (it) 1989-08-11
IT1231727B true IT1231727B (it) 1991-12-21

Family

ID=11182983

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8921517A IT1231727B (it) 1989-08-11 1989-08-11 Peptidi utili per la determinazione e la purificazione di anticorpi anti gamma interferone.

Country Status (6)

Country Link
EP (1) EP0485471B1 (it)
JP (1) JPH05500360A (it)
AU (1) AU6176690A (it)
DE (1) DE69008535T2 (it)
IT (1) IT1231727B (it)
WO (1) WO1991002005A1 (it)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
DE69115917T2 (de) * 1990-09-27 1996-05-23 Schering Corp Humane gammainterferonantagonisten
US5888511A (en) * 1993-02-26 1999-03-30 Advanced Biotherapy Concepts, Inc. Treatment of autoimmune diseases, including AIDS
DK96493D0 (da) * 1993-08-26 1993-08-26 Mouritsen Og Elsner Aps Fremgangsmaade til at inducere antistofresponser mod selvproteiner og autovaccine fremstillet ved fremgangsmaaden
US20020025316A1 (en) 1995-08-18 2002-02-28 Ferguson Mark Williams James Pharmaceutical composition containing inhibitors of interferon-gamma
GB2304342A (en) * 1995-08-18 1997-03-19 Univ Manchester Pharmaceutical comprising either an inhibitor or a stimulator of interferon gamma
CA2353520C (en) 1998-12-09 2006-04-25 Protein Design Labs, Inc. Animal model for psoriasis for the prevention and treatment of psoriasis in humans
US7084257B2 (en) 2001-10-05 2006-08-01 Amgen Inc. Fully human antibody Fab fragments with human interferon-gamma neutralizing activity
AU2003285874A1 (en) * 2002-10-16 2004-05-04 Amgen Inc. HUMAN ANTI-IFN-Gamma NEUTRALIZING ANTIBODIES AS SELECTIVE IFN-Gamma PATHWAY INHIBITORS
EP1560595A4 (en) * 2002-10-17 2005-12-28 Amgen Inc HUMAN GAMMA INTERFERON NEUTRALIZING FAB FRAGMENTS OF FULL HUMAN ANTIBODY
WO2022005408A1 (en) * 2020-06-29 2022-01-06 Mahidol University Immunochromatographic method and kit for detecting anti-interferon gamma antibody
CN116769026A (zh) * 2023-05-11 2023-09-19 广州医科大学附属第一医院 一种抗IFN-γ自身抗体的纯化工艺及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4681848A (en) * 1982-09-22 1987-07-21 Takeda Chemical Industries, Ltd. Novel peptide and use thereof
US4599306A (en) * 1983-04-15 1986-07-08 Amgen Monoclonal antibodies which specifically bind to human immune interferon
US4473555A (en) * 1983-10-17 1984-09-25 Syntex (U.S.A.) Inc. Nona- and dodecapeptides for augmenting natural killer cell activity
DE3426077A1 (de) * 1984-07-14 1986-01-23 Dr. Karl Thomae Gmbh, 7950 Biberach Monoklonale antikoerper gegen humanes ifn-(gamma), diese antikoerper produzierende hybridzellinien, verwendung der neuen antikoerper und verfahren zu deren herstellung
NL8700927A (nl) * 1987-04-16 1988-11-16 Stichting Rega V Z W Anti-interferon-gamma-antilichamen; en hun therapeutische toepassing.
CA1335792C (en) * 1987-08-18 1995-06-06 Chaim O. Jacob Method and dosage form using an antagonist to gamma interferon to control mhc-associated autoimmune disease

Also Published As

Publication number Publication date
DE69008535D1 (de) 1994-06-01
AU6176690A (en) 1991-03-11
DE69008535T2 (de) 1994-12-15
EP0485471A1 (en) 1992-05-20
IT8921517A0 (it) 1989-08-11
JPH05500360A (ja) 1993-01-28
EP0485471B1 (en) 1994-04-27
WO1991002005A1 (en) 1991-02-21

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970828