ME00205B - HUMANA ANTI-IFN-γ NEUTRALIŠUĆA ANTITELA KAO SELEKTIVNI INHIBITORI IFN-γ PUTA - Google Patents

HUMANA ANTI-IFN-γ NEUTRALIŠUĆA ANTITELA KAO SELEKTIVNI INHIBITORI IFN-γ PUTA

Info

Publication number
ME00205B
ME00205B MEP-2008-303A MEP2008303A ME00205B ME 00205 B ME00205 B ME 00205B ME P2008303 A MEP2008303 A ME P2008303A ME 00205 B ME00205 B ME 00205B
Authority
ME
Montenegro
Prior art keywords
ifn
neutralizing antibodies
human anti
selective
pathway inhibitors
Prior art date
Application number
MEP-2008-303A
Other languages
English (en)
French (fr)
Inventor
Yue Sheng Li
Andrew A Welcher
Hilary T Chute
Haichun Huang
Original Assignee
Medarex Llc
Squibb & Sons Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medarex Llc, Squibb & Sons Llc filed Critical Medarex Llc
Publication of ME00205B publication Critical patent/ME00205B/me

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/249—Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P5/16—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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Abstract

Predmetni pronalazak obezbeđuje antitela koja interaguju ili se vezuju za interferongama (IFN-y), kao i postupke za lečenje oboljenja koja su posredovana IFN-y, putem primenefarmaceutski efikasne količine antitela za IFN-y. Takođe su obezbeđeni i postupci zadetekciju količine IFN-g u uzorku, korišćenjem antitela za IFN-y.
MEP-2008-303A 2002-10-16 2003-10-16 HUMANA ANTI-IFN-γ NEUTRALIŠUĆA ANTITELA KAO SELEKTIVNI INHIBITORI IFN-γ PUTA ME00205B (me)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US41905702P 2002-10-16 2002-10-16
US47924103P 2003-06-17 2003-06-17
EP10075518.0A EP2298811B8 (en) 2002-10-16 2003-10-16 Human anti-IFN-gamma neutralizing antibodies as selective IFN-gamma pathway inhibitors
PCT/US2003/032871 WO2004035747A2 (en) 2002-10-16 2003-10-16 Human anti-ifn-ϝ neutralizing antibodies as selective ifn-ϝ pathway inhibitors

Publications (1)

Publication Number Publication Date
ME00205B true ME00205B (me) 2011-02-10

Family

ID=32110210

Family Applications (2)

Application Number Title Priority Date Filing Date
MEP-303/08A MEP30308A (en) 2002-10-16 2003-10-16 HUMAN ANTI-IFN-gamma NEUTRALIZING ANTIBODIES AS SELECTIVE IFN-gamma PATHWAY INHIBITORS
MEP-2008-303A ME00205B (me) 2002-10-16 2003-10-16 HUMANA ANTI-IFN-γ NEUTRALIŠUĆA ANTITELA KAO SELEKTIVNI INHIBITORI IFN-γ PUTA

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MEP-303/08A MEP30308A (en) 2002-10-16 2003-10-16 HUMAN ANTI-IFN-gamma NEUTRALIZING ANTIBODIES AS SELECTIVE IFN-gamma PATHWAY INHIBITORS

Country Status (27)

Country Link
US (5) US7335743B2 (me)
EP (2) EP1578936B1 (me)
JP (2) JP4252061B2 (me)
KR (1) KR100816124B1 (me)
CN (1) CN1820026B (me)
AT (1) ATE520416T1 (me)
AU (2) AU2003285874A1 (me)
BR (1) BR0315161A (me)
CA (1) CA2501653C (me)
CY (1) CY1111812T1 (me)
DK (1) DK1578936T3 (me)
EA (1) EA011876B1 (me)
EG (1) EG26731A (me)
ES (1) ES2370473T3 (me)
HK (1) HK1084689A1 (me)
IL (1) IL167436A (me)
ME (2) MEP30308A (me)
MX (1) MXPA05003907A (me)
NO (1) NO336802B1 (me)
NZ (1) NZ538893A (me)
PL (1) PL377338A1 (me)
PT (1) PT1578936E (me)
RS (1) RS52690B (me)
SG (1) SG155054A1 (me)
SI (1) SI1578936T1 (me)
WO (2) WO2004034988A2 (me)
ZA (1) ZA200503821B (me)

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