DK1146049T3 - Fremgangsmåde til separering af dobbeltstrengede/enkeltstrengede nucleinsyrestrukturer - Google Patents

Fremgangsmåde til separering af dobbeltstrengede/enkeltstrengede nucleinsyrestrukturer

Info

Publication number
DK1146049T3
DK1146049T3 DK01113857T DK01113857T DK1146049T3 DK 1146049 T3 DK1146049 T3 DK 1146049T3 DK 01113857 T DK01113857 T DK 01113857T DK 01113857 T DK01113857 T DK 01113857T DK 1146049 T3 DK1146049 T3 DK 1146049T3
Authority
DK
Denmark
Prior art keywords
eluted
ghc
gtc
plus
ionic strength
Prior art date
Application number
DK01113857T
Other languages
English (en)
Inventor
Simone Gauch
Helge Bastian
Petra Feuser-Frank
Colpan Metin
Original Assignee
Qiagen Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6510036&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1146049(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Qiagen Gmbh filed Critical Qiagen Gmbh
Application granted granted Critical
Publication of DK1146049T3 publication Critical patent/DK1146049T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C12N15/101—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by chromatography, e.g. electrophoresis, ion-exchange, reverse phase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DK01113857T 1994-02-11 1995-02-08 Fremgangsmåde til separering af dobbeltstrengede/enkeltstrengede nucleinsyrestrukturer DK1146049T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4404361 1994-02-11

Publications (1)

Publication Number Publication Date
DK1146049T3 true DK1146049T3 (da) 2005-12-12

Family

ID=6510036

Family Applications (2)

Application Number Title Priority Date Filing Date
DK95909684T DK0743950T3 (da) 1994-02-11 1995-02-08 Fremgangsmåde til adskillelse af dobbeltstrengede/enkeltstrengede nukleinsyre-strukturer
DK01113857T DK1146049T3 (da) 1994-02-11 1995-02-08 Fremgangsmåde til separering af dobbeltstrengede/enkeltstrengede nucleinsyrestrukturer

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK95909684T DK0743950T3 (da) 1994-02-11 1995-02-08 Fremgangsmåde til adskillelse af dobbeltstrengede/enkeltstrengede nukleinsyre-strukturer

Country Status (7)

Country Link
US (3) US6180778B1 (da)
EP (2) EP1146049B1 (da)
JP (2) JP3256238B2 (da)
AT (2) ATE210671T1 (da)
DE (2) DE59509941D1 (da)
DK (2) DK0743950T3 (da)
WO (1) WO1995021849A1 (da)

Families Citing this family (134)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1146049B1 (de) * 1994-02-11 2005-08-17 Qiagen GmbH Verfahren zur Trennung von Doppelstrang/Einzelstrangnukleinsäurestrukturen
DE29601618U1 (de) * 1996-01-31 1996-07-04 InViTek GmbH, 13125 Berlin Vorrichtung zur gleichzeitigen multiplen Isolierung
AU1676597A (en) * 1996-02-14 1997-09-02 Amsterdam Support Diagnostics B.V. Separation of single stranded and double stranded nucleic acid materials
JP3943597B2 (ja) * 1996-02-14 2007-07-11 アクゾ・ノベル・エヌ・ベー 核酸物質の単離及び増幅
NL1002781C1 (nl) * 1996-04-03 1997-10-06 Amsterdam Support Diagnostics Isolatie en/of amplificatie van hepatitis-C-virus-(HCV) -nucleïnezuren uit monsters waarvan vermoed wordt dat zij HCV bevatten.
EP0814156B1 (en) * 1996-06-18 2003-03-05 The Institute Of Physical & Chemical Research Method for the purification of DNA
US6872527B2 (en) 1997-04-16 2005-03-29 Xtrana, Inc. Nucleic acid archiving
DE19746874A1 (de) 1997-10-23 1999-04-29 Qiagen Gmbh Verfahren zur Isolierung und Reinigung von Nukleinsäuren an hydrophoben Oberflächen - insbesondere unter Verwendung hydrophober Membranen
CA2313654A1 (en) * 1997-12-10 1999-06-17 Sierra Diagnostics, Inc. Methods and reagents for preservation of dna in bodily fluids
CA2319691C (en) * 1998-02-02 2012-12-18 Gentra Systems, Inc. Eluting reagents, methods and kits for isolating dna
US7078224B1 (en) * 1999-05-14 2006-07-18 Promega Corporation Cell concentration and lysate clearance using paramagnetic particles
EP0959141A2 (en) * 1998-05-20 1999-11-24 Hitachi, Ltd. Method of preparing nucleic acid sample for rare expressed genes and analysing method using the nucleic acid prepared thereby
EP0969090A1 (en) * 1998-05-27 2000-01-05 QIAGEN GmbH Rapid and simple process for isolation of circular nucleic acids
DE10031236A1 (de) 2000-06-27 2002-01-10 Qiagen Gmbh Verwendung von Carbonsäuren und anderen Additiven in Kombination mit kationischen Verbindungen zur Stabilisierung von Nukleinsäuren in biologischen Materialien
DE10033991A1 (de) * 2000-07-12 2002-01-24 Qiagen Gmbh Verfahren zur Isolierung von Nukleinsäuren
WO2002046398A2 (en) * 2000-11-06 2002-06-13 The University Of Houston System Nucleic acid separation using immobilized metal affinity chromatography
US20050032105A1 (en) 2001-10-12 2005-02-10 Bair Robert Jackson Compositions and methods for using a solid support to purify DNA
WO2003046146A2 (en) * 2001-11-28 2003-06-05 Applera Corporation Compositions and methods of selective nucleic acid isolation
WO2003095974A2 (en) * 2002-05-07 2003-11-20 Becton, Dickinson And Company Collection assembly
WO2004013279A2 (en) * 2002-05-14 2004-02-12 Fidelity Systems, Inc. Helix-hairpin-helix motifs to manipulate properties of dna processing enzymes
DE10222133A1 (de) * 2002-05-17 2003-12-04 Gl Biotech Gmbh Verfahren zur Nukleinsäure-Extraktion und Nukleinsäure-Reinigung
WO2004035170A2 (en) * 2002-10-18 2004-04-29 Promega Corporation Composition for separating molecules
AU2003291931A1 (en) † 2002-11-08 2004-06-07 Invitek Gesellschaft Fur Biotechnik And Biodesign Mbh Novel buffer formulations for isolating, purifying and recovering long-chain and short-chain nucleic acids
US20040121336A1 (en) * 2002-12-20 2004-06-24 Greenfield I Lawrence Method for generating multiple samples containing a predetermined amount of nucleic acid
JP3644641B2 (ja) * 2003-03-07 2005-05-11 株式会社日立ハイテクノロジーズ 核酸回収方法
US7267950B2 (en) * 2003-05-01 2007-09-11 Veridex, Lcc Rapid extraction of RNA from cells and tissues
JP4241183B2 (ja) * 2003-05-19 2009-03-18 株式会社日立ハイテクノロジーズ 核酸回収方法及び核酸回収キット
US8377715B2 (en) * 2003-07-14 2013-02-19 Phynexus, Inc. Method and device for sample preparation
US20050059024A1 (en) * 2003-07-25 2005-03-17 Ambion, Inc. Methods and compositions for isolating small RNA molecules
JP4871722B2 (ja) † 2003-07-25 2012-02-08 アプライド バイオシステムズ リミテッド ライアビリティー カンパニー 固定試料からｒｎａを調製するための方法および組成物
WO2005012487A2 (en) 2003-08-01 2005-02-10 Invitrogen Corporation Compositions and methods for preparing short rna molecules and other nucleic acids
US7031802B2 (en) * 2003-08-13 2006-04-18 Hewlett-Packard Development Company, L.P. Semi-autonomous operation of a robotic device
JP3714940B2 (ja) * 2003-11-07 2005-11-09 株式会社日立ハイテクノロジーズ Ｒｎａ抽出方法、および生体材料の分析方法
KR20050061767A (ko) * 2003-12-18 2005-06-23 삼성전자주식회사 알루미나를 이용한 핵산의 정제 방법
JP4690656B2 (ja) * 2004-02-12 2011-06-01 ジーエルサイエンス株式会社 核酸の分離精製方法及び分離吸着体
AU2005200670B2 (en) * 2004-02-20 2007-05-03 F. Hoffmann-La Roche Ag Adsorption of nucleic acids to a solid phase
CA2502549C (en) * 2004-04-23 2016-02-16 Becton, Dickinson And Company Use of an extraction control in a method of extracting nucleic acids
DE102004045332B3 (de) * 2004-09-16 2006-03-09 Macherey, Nagel Gmbh & Co. Handelsgesellschaft Verfahren zur Isolierung und Trennung von einzel- und doppelsträngigen Nucleinsäuren aus einer diese Nucleinsäuren enthaltenden Probe sowie Trennsäule zur Durchführung dieses Verfahrens
EP1809744B1 (en) 2004-11-05 2018-06-06 QIAGEN North American Holdings, Inc. Compositions and methods for purifying nucleic acids from stabilization reagents
US20070042384A1 (en) * 2004-12-01 2007-02-22 Weiwei Li Method for isolating and modifying DNA from blood and body fluids
KR20070103417A (ko) * 2005-01-21 2007-10-23 더 뉴욕 블러드 센터, 인코포레이티드 핵산의 추출 및 확인방법
DE102005015005A1 (de) 2005-04-01 2006-10-05 Qiagen Gmbh Verfahren zur Behandlung einer Biomoleküle enthaltenden Probe
JP4699868B2 (ja) 2005-11-04 2011-06-15 株式会社日立ハイテクノロジーズ 核酸精製方法及び核酸精製器具
DE102005053463A1 (de) * 2005-11-06 2007-05-10 Aj Innuscreen Gmbh Vorrichtung und Verfahren zur automatisierten Isolierung und Aufreinigung von Nukleinsäuren aus beliebigen komplexen Ausgangsmaterialien
WO2007070381A2 (en) * 2005-12-09 2007-06-21 Promega Corporation Nucleic acid purification with a binding matrix
US20070202511A1 (en) * 2006-02-28 2007-08-30 Sigma-Aldrich Co. Methods and compositions for the rapid isolation of small RNA molecules
WO2007103485A2 (en) * 2006-03-08 2007-09-13 Promega Corporation Small rna purification
WO2007140417A2 (en) * 2006-05-31 2007-12-06 Sequenom, Inc. Methods and compositions for the extraction and amplification of nucleic acid from a sample
US20080153078A1 (en) * 2006-06-15 2008-06-26 Braman Jeffrey C System for isolating biomolecules from a sample
US8163535B2 (en) * 2006-06-26 2012-04-24 Blood Cell Storage, Inc. Devices and processes for nucleic acid extraction
US20080102493A1 (en) * 2006-06-29 2008-05-01 Millipore Corporation Isolation of RNA and DNA from a biological sample
DE102006031764B4 (de) * 2006-07-06 2009-10-01 Aj Innuscreen Gmbh Verfahren zur parallelen Isolierung doppel- und einzelsträngiger Nukleinsäuren sowie zur selektiven Entfernung doppelsträngiger Nukleinsäuren aus einem Gemisch von doppel- und einzelsträngigen Nukleinsäuren
US10131935B2 (en) * 2006-07-11 2018-11-20 Aj Innuscreen Gmbh Method for parallel isolation of viral nucleic acids
GB2445441B (en) 2006-09-26 2010-06-30 Ge Healthcare Bio Sciences Nucleic acid purification method
EP1911844A1 (en) 2006-10-10 2008-04-16 Qiagen GmbH Methods and kit for isolating nucleic acids
EP2094846B8 (en) * 2006-12-13 2013-10-16 Roche Diagnostics GmbH Use of tde for the isolation of nucleic acids
US8686129B2 (en) * 2007-03-20 2014-04-01 Agilent Technologies, Inc. Methods for the separation of biological molecules using sulfolane
US9624464B2 (en) * 2007-10-03 2017-04-18 3M Innovative Properties Company Microorganism concentration process
WO2009046191A2 (en) * 2007-10-03 2009-04-09 3M Innovative Properties Company Microorganism concentration process and agent
BRPI0817422A8 (pt) * 2007-10-03 2019-01-29 3M Innovative Properties Co processo de concentração de microorganismos
CN101918829A (zh) * 2007-11-20 2010-12-15 3M创新有限公司 检测装置和方法
DE102008010692A1 (de) 2008-02-22 2009-08-27 Qiagen Gmbh Neue Matrices, Verfahren zu ihrer Herstellung und ihre Verwendung in Verfahren zur Isolierung von Biomolekülen
DE102008010693A1 (de) 2008-02-22 2009-08-27 Qiagen Gmbh Neue Matrixmaterialien, Verfahren zu ihrer Herstellung und ihre Verwendung in Verfahren zur Isolierung von Biomolekülen
US7871764B1 (en) * 2008-03-18 2011-01-18 The United States Of America As Represented By The United States Department Of Energy Universal nucleic acids sample preparation method for cells, spores and their mixture
US20110046361A1 (en) * 2008-04-30 2011-02-24 Ge Healthcare Bio-Sciences Corp. Method for separation of double-stranded and single-stranded nucleic acids
DE102008026058A1 (de) 2008-05-30 2009-12-03 Qiagen Gmbh Lyse, Binde- und/oder Waschreagenz verwendbar zur Isolierung und/oder Reinigung von Nukleinsäuren
EP2128169A1 (de) 2008-05-30 2009-12-02 Qiagen GmbH Verfahren zur Isolierung von kurzkettigen Nukleinsäuren
US8648187B2 (en) * 2008-06-18 2014-02-11 Ge Healthcare Bio-Sciences Corp. Method for separation of double-stranded and single-stranded nucleic acids from the same sample
US20110224913A1 (en) * 2008-08-08 2011-09-15 Juan Cui Methods and systems for predicting proteins that can be secreted into bodily fluids
EP2163620A1 (de) 2008-09-03 2010-03-17 Qiagen GmbH Verfahren zum Isolieren und Reinigen von Nukleinsäuren
CN102325894A (zh) 2008-12-31 2012-01-18 3M创新有限公司 大肠菌检测方法以及其中使用的试剂盒
US8293101B2 (en) 2009-03-13 2012-10-23 Terrasep, Llc Methods and apparatus for centrifugal liquid chromatography
CA2757493C (en) 2009-04-03 2018-11-13 Sequenom, Inc. Nucleic acid preparation compositions and methods
US8039613B2 (en) 2009-08-28 2011-10-18 Promega Corporation Methods of purifying a nucleic acid and formulation and kit for use in performing such methods
US8222397B2 (en) * 2009-08-28 2012-07-17 Promega Corporation Methods of optimal purification of nucleic acids and kit for use in performing such methods
EP2345719A1 (en) 2010-01-18 2011-07-20 Qiagen GmbH Method for isolating small RNA
PL2588609T3 (pl) 2010-06-29 2018-06-29 Exscale Biospecimen Solutions Ab Sposób i zestaw do sekwencyjnej izolacji nukleotydów z próbki
EP2407540A1 (en) 2010-07-15 2012-01-18 Qiagen GmbH Method for purifying a target nucleic acid
ES2617778T3 (es) 2010-09-02 2017-06-19 Qiagen Gmbh Método para aislar un ácido nucleico diana que incluye ácidos nucleicos diana pequeños, con alto rendimiento
US8816064B2 (en) 2010-09-30 2014-08-26 Phynexus, Inc. Purification of nucleic acids
CN104946626A (zh) * 2011-01-12 2015-09-30 积水医疗株式会社 离子交换色谱法用洗脱液以及核酸链的分析方法
US20140147842A1 (en) 2011-01-12 2014-05-29 Sekisui Medical Co. Ltd Method for detecting single nucleotide polymorphisms
AU2012253366A1 (en) * 2011-05-11 2014-01-09 Exosome Diagnostics, Inc. Nucleic acid extraction from heterogeneous biological materials
CN102250876B (zh) 2011-05-18 2014-08-13 李学敬 从生物材料中分离纯化rna的方法
EP3216877B1 (en) * 2011-08-12 2020-10-21 QIAGEN GmbH Method for isolating nucleic acids
JP2014526255A (ja) 2011-09-13 2014-10-06 キアゲン ゲーエムベーハー 獣医学的全血試料から核酸を単離するための方法
AU2012314515B2 (en) 2011-09-26 2018-03-15 Preanalytix Gmbh Stabilisation and isolation of extracellular nucleic acids
EP4397770A1 (en) 2011-09-26 2024-07-10 PreAnalytiX GmbH Stabilisation and isolation of extracellular nucleic acids
US11021733B2 (en) 2011-09-26 2021-06-01 Qiagen Gmbh Stabilization and isolation of extracellular nucleic acids
ES2693672T3 (es) 2011-09-26 2018-12-13 Qiagen Gmbh Método rápido para aislar ácidos nucleicos extracelulares
US20150225712A1 (en) 2012-08-21 2015-08-13 Qiagen Gmbh Method for isolating nucleic acids from a formaldehyde releaser stabilized sample
EP2888354B1 (en) 2012-08-21 2020-04-01 Qiagen GmbH Virus particle stabilisation and method for isolating viral nucleic acids
SG11201500655VA (en) 2012-09-03 2015-05-28 Qiagen Gmbh Method for isolating rna including small rna with high yield
WO2014044724A1 (en) 2012-09-18 2014-03-27 Qiagen Gmbh Method and kit for preparing a target rna depleted sample
US10724074B2 (en) 2012-09-25 2020-07-28 Qiagen Gmbh Stabilisation of biological samples
WO2014071070A1 (en) * 2012-11-01 2014-05-08 Pacific Biosciences Of California, Inc. Compositions and methods for selection of nucleic acids
KR101984700B1 (ko) 2012-11-19 2019-05-31 삼성전자주식회사 폴리뉴클레오티드 및 그의 용도
EP2931661B1 (en) 2012-12-11 2017-11-08 Qiagen GmbH Preparation of silica particles
US9556427B2 (en) * 2013-02-27 2017-01-31 Syngenta Participations Ag Methods and compositions for preparation of nucleic acids
WO2014160233A1 (en) * 2013-03-13 2014-10-02 Abbott Molecular Inc. Systems and methods for isolating nucleic acids
SG11201507425RA (en) * 2013-03-14 2015-10-29 Shire Human Genetic Therapies Methods for purification of messenger rna
US10077439B2 (en) * 2013-03-15 2018-09-18 Modernatx, Inc. Removal of DNA fragments in mRNA production process
EP2969140B1 (en) * 2013-03-15 2021-02-17 Abbott Molecular Inc. One-step procedure for the purification of nucleic acids
US11525155B2 (en) 2013-03-18 2022-12-13 Qiagen Gmbh Stabilisation of biological samples
JP6407248B2 (ja) 2013-03-18 2018-10-17 キアゲン ゲーエムベーハー 細胞外核酸の安定化および単離
CA2940692A1 (en) 2014-03-18 2015-09-24 Qiagen Gmbh Stabilization and isolation of extracellular nucleic acids
SG11201608575QA (en) * 2014-04-18 2016-11-29 Toppan Printing Co Ltd Method for recovering short-chain nucleic acids
JP6571679B2 (ja) * 2014-04-25 2019-09-04 トランスレイト バイオ， インコーポレイテッド メッセンジャーｒｎａの精製方法
EP2940136A1 (en) 2014-04-30 2015-11-04 QIAGEN GmbH Method for isolating poly(A) nucleic acids
US11091810B2 (en) * 2015-01-27 2021-08-17 BioSpyder Technologies, Inc. Focal gene expression profiling of stained FFPE tissues with spatial correlation to morphology
WO2016094465A1 (en) * 2014-12-09 2016-06-16 Corning Incorporated Methods and kits for purifying plasmid dna
GB201504459D0 (en) 2015-03-17 2015-04-29 Moorlodge Biotech Ventures Ltd Isolation of DNA
EP3719141B1 (en) 2015-04-20 2023-01-25 QIAGEN GmbH Method, lysis solution and kit for selectively depleting animal nucleic acids in a sample
EP3885438A1 (en) 2015-06-10 2021-09-29 QIAGEN GmbH Method for isolating extracellular nucleic acids using anion exchange particles
WO2017040992A1 (en) 2015-09-04 2017-03-09 Mo Bio Laboratories, Inc. Methods for co-isolation of nucelic acids and proteins
CN105087549A (zh) * 2015-09-16 2015-11-25 吉林大学 一种同时高效提取rna和dna的方法及试剂
US10214739B2 (en) * 2015-10-30 2019-02-26 Axagarius Gmbh & Co. Kg RNA binding solution
JP7166169B2 (ja) 2015-11-20 2022-11-07 キアゲン ゲーエムベーハー 細胞外核酸の滅菌のための滅菌組成物を調製する方法
US10287625B2 (en) * 2016-03-18 2019-05-14 Norgen Biotek Corp. Methods and kits for separating nucleic acids by size
AU2017261283B2 (en) * 2016-05-04 2023-02-09 Children's Hospital & Research Center At Oakland Rapid extraction of nucleic acids from clinical samples for downstream applications
US10428370B2 (en) 2016-09-15 2019-10-01 Sun Genomics, Inc. Universal method for extracting nucleic acid molecules from a diverse population of one or more types of microbes in a sample
US11959125B2 (en) * 2016-09-15 2024-04-16 Sun Genomics, Inc. Universal method for extracting nucleic acid molecules from a diverse population of one or more types of microbes in a sample
CN110249048A (zh) * 2016-09-15 2019-09-17 太阳基因组学公司 用于从样品中的一种或多种类型的微生物的多样性群体中提取核酸分子的通用方法
CN110050070B (zh) * 2016-12-22 2023-12-22 文塔纳医疗系统公司 用于组织样品的全自动化核酸提取方法
WO2018157141A1 (en) * 2017-02-27 2018-08-30 Translate Bio, Inc. Methods for purification of messenger rna
WO2019014486A1 (en) 2017-07-12 2019-01-17 Exosome Diagnostics, Inc. METHODS FOR ISOLATING AND ENRICHING POPULATIONS OF EXTRACELLULAR VESICLES DERIVED FROM BIOFLUIDS, AND METHODS OF USE THEREOF
WO2019063071A1 (en) 2017-09-27 2019-04-04 Qiagen Gmbh METHOD FOR HIGH-PERFORMANCE RNA ISOLATION
WO2019067388A1 (en) * 2017-09-30 2019-04-04 The Regents Of The University Of California EXTRACTION OF SHORT NUCLEIC ACIDS BY NANOFIBERS
EP4410977A2 (en) * 2018-04-24 2024-08-07 QIAGEN Sciences, LLC Nucleic acid isolation and inhibitor removal from complex samples
KR102117833B1 (ko) * 2019-01-04 2020-06-02 남장희 생물시료로부터 유전물질을 신속하게 분리하는 핵산 흡착 물질을 포함하는 조성물 및 그를 이용하여 생물시료로부터 유전물질을 신속하게 분리하는 방법
CN118599961A (zh) 2019-01-04 2024-09-06 凯杰有限公司 尿液稳定化
MX2022001468A (es) 2019-08-09 2022-07-19 Nutcracker Therapeutics Inc Metodos y aparatos de fabricación para remover material de una composición terapeutica.
CN111808844A (zh) * 2020-07-29 2020-10-23 广州捷倍斯生物科技有限公司 一种同时提取dna和rna的试剂盒及其使用方法
CN115197935A (zh) * 2021-04-08 2022-10-18 上海细胞治疗集团有限公司 纤维素色谱纯化rna的方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4493892A (en) * 1982-12-20 1985-01-15 Memorial Hospital For Cancer & Allied Diseases Solvent system for peroxidase inhibitor reagent for fecal occult blood determinations
JPH01135792A (ja) * 1987-11-20 1989-05-29 Mitsui Toatsu Chem Inc 核酸の分離・精製方法
DE68907519T2 (de) 1988-05-10 1993-10-21 Amersham Int Plc Biosensoren.
US5017726A (en) 1988-11-09 1991-05-21 Union Camp Corporation Processes for the conversion of myrcene to nerol and citral
US5075430A (en) 1988-12-12 1991-12-24 Bio-Rad Laboratories, Inc. Process for the purification of DNA on diatomaceous earth
NL8900725A (nl) 1989-03-23 1990-10-16 Az Univ Amsterdam Werkwijze en combinatie van middelen voor het isoleren van nucleinezuur.
US5232830A (en) * 1990-05-11 1993-08-03 Microprobe Corporation Intrinsic fluorescent quenching methods
EP0519338B1 (en) * 1991-06-20 1996-08-28 F. Hoffmann-La Roche Ag Improved methods for nucleic acid amplification
US5155018A (en) * 1991-07-10 1992-10-13 Hahnemann University Process and kit for isolating and purifying RNA from biological sources
DE4139664A1 (de) * 1991-12-02 1993-06-03 Diagen Inst Molekularbio Vorrichtung und verfahren zur isolierung und reinigung von nukleinsaeuren
US5268097A (en) * 1992-06-19 1993-12-07 Sepracor Inc. Passivated and stabilized porous mineral oxide supports and method for the preparation and use of same
DE69326507T2 (de) * 1992-07-02 2000-04-27 Edge Biosystems Inc., Gaithersburg Verfahren und Material für Reinigung von Nukleinsäuren
EP1146049B1 (de) * 1994-02-11 2005-08-17 Qiagen GmbH Verfahren zur Trennung von Doppelstrang/Einzelstrangnukleinsäurestrukturen

Also Published As

Publication number Publication date
JPH09508638A (ja) 1997-09-02
US6180778B1 (en) 2001-01-30
EP1146049B1 (de) 2005-08-17
EP1146049A3 (de) 2001-10-24
US20020081619A1 (en) 2002-06-27
JP3256238B2 (ja) 2002-02-12
DE59509941D1 (de) 2002-01-24
US20030224389A1 (en) 2003-12-04
WO1995021849A1 (de) 1995-08-17
JP2002187897A (ja) 2002-07-05
ATE210671T1 (de) 2001-12-15
EP1146049A2 (de) 2001-10-17
US6946250B2 (en) 2005-09-20
ATE302208T1 (de) 2005-09-15
DE59511013D1 (de) 2005-09-22
EP0743950B1 (de) 2001-12-12
DK0743950T3 (da) 2002-03-25
US7074916B2 (en) 2006-07-11
EP0743950A1 (de) 1996-11-27
JP4036625B2 (ja) 2008-01-23

Similar Documents

Publication Publication Date Title
DK1146049T3 (da) Fremgangsmåde til separering af dobbeltstrengede/enkeltstrengede nucleinsyrestrukturer
IN2001KO01049A (da)
WO2002004358A8 (en) System and method for removal of arsenic from aqueous solutions
CA2041121A1 (en) High speed electroplating of tinplate
GB9603741D0 (en) Treatment of water by electrolysis
DE536017T1 (de) Verfahren und anlage fuer die biologische abwasserbehandlung.
CA2236125A1 (en) Method for purifying nickel sulfate
ATE209165T1 (de) Terpolymer als inhibierungsmittel von krustenbildung und wasserbehandlungsverfahren
AU2001276862A1 (en) Method of cleaning a metal surface
EP1364914A4 (en) METHOD AND SYSTEM FOR TREATING NITROGEN-CONTAINING COMPONENTS
CA2121387A1 (en) Method for Bleaching Lignocellulose-Containing Pulp
CA2031229A1 (en) Fluoride removal from sulphuric acid
DK0613391T3 (da) Immobilisering af metalurenheder fra et flydende til et fast medium
PL342141A1 (en) Method of purifying recalculated water in a painting equipment
AU6400401A (en) Method for oxidising treatment of steel works slag and resulting ld slag
WO2001038605A3 (de) Verfahren zur phosphatierung mit metallhaltiger nachspülung
EP0864533A3 (en) Method of purifying alkaline solution and method of etching semiconductor wafers
DE60000499D1 (de) Verfahren und Bad zur selektiven Bleientfernung von Sanitärkomponenten aus Kupferlegierungen
DE10344198A1 (de) Verfahren und Anlage zum Erhöhen der Produktivität beim Stahlherstellen, insbesondere zum Verkürzen der Lieferzeiten, bei Vermehrung der Stahlgüten und Kontrollieren der Qualität von Massen- und hochwertigen Stählen
WO2001068930A3 (en) Removal of 'copper kiss' from pickling high copper alloys
CA2031028A1 (en) Process for purification of nickel plating baths
AU2002214520A1 (en) Method for the recovery of iron from acidic, metal-contaminated water
KR970043338A (ko) 밀 스케일을 이용한 산세 폐액 정제방법
JPH06170366A (ja) 洗浄廃液の処理方法
UA28465A (uk) Спосіб окислення заліза у воді перед підготовкою води до електродіалізу