DK1128815T3 - Fremgangsmåde til fremstilling af orale calcium-kompositioner - Google Patents

Fremgangsmåde til fremstilling af orale calcium-kompositioner

Info

Publication number
DK1128815T3
DK1128815T3 DK99952710T DK99952710T DK1128815T3 DK 1128815 T3 DK1128815 T3 DK 1128815T3 DK 99952710 T DK99952710 T DK 99952710T DK 99952710 T DK99952710 T DK 99952710T DK 1128815 T3 DK1128815 T3 DK 1128815T3
Authority
DK
Denmark
Prior art keywords
granulate
preparation
produce
mixing
calcium compound
Prior art date
Application number
DK99952710T
Other languages
Danish (da)
English (en)
Inventor
Dina Dogger Schmidt
Jan Yngvar Piene
Original Assignee
Nycomed Pharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Pharma As filed Critical Nycomed Pharma As
Application granted granted Critical
Publication of DK1128815T3 publication Critical patent/DK1128815T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
DK99952710T 1998-11-13 1999-11-05 Fremgangsmåde til fremstilling af orale calcium-kompositioner DK1128815T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9825033.5A GB9825033D0 (en) 1998-11-13 1998-11-13 Process
PCT/GB1999/003666 WO2000028973A1 (en) 1998-11-13 1999-11-05 Process for preparing oral calcium compositions

Publications (1)

Publication Number Publication Date
DK1128815T3 true DK1128815T3 (da) 2007-02-05

Family

ID=10842483

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99952710T DK1128815T3 (da) 1998-11-13 1999-11-05 Fremgangsmåde til fremstilling af orale calcium-kompositioner

Country Status (22)

Country Link
US (3) US20050232989A1 (el)
EP (2) EP1128815B1 (el)
JP (1) JP4213867B2 (el)
CN (1) CN1183902C (el)
AT (1) ATE342714T1 (el)
AU (1) AU6481999A (el)
CA (1) CA2349565C (el)
CY (1) CY1106299T1 (el)
DE (1) DE69933689T2 (el)
DK (1) DK1128815T3 (el)
EA (1) EA004951B1 (el)
EE (1) EE04740B1 (el)
ES (1) ES2273510T3 (el)
GB (1) GB9825033D0 (el)
HK (1) HK1040615B (el)
NO (1) NO331462B1 (el)
PL (1) PL197146B1 (el)
PT (1) PT1128815E (el)
SI (1) SI1128815T1 (el)
TR (1) TR200101347T2 (el)
UA (1) UA73727C2 (el)
WO (1) WO2000028973A1 (el)

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US7198653B2 (en) 2003-07-31 2007-04-03 Delavau Llc Calcium carbonate granulation
JP4601934B2 (ja) * 2003-10-06 2010-12-22 ナガセ医薬品株式会社 ユビデカレノン錠
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NZ551536A (en) 2004-05-24 2010-10-29 Nycomed Pharma As Particulate comprising a calcium-containing compound and a sugar alcohol
WO2005117829A2 (en) * 2004-06-01 2005-12-15 Nycomed Pharma As Chewable, suckable and swallowable tablet containing a calcium-containing compound as an active substance
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EP1845950A2 (en) * 2005-02-03 2007-10-24 Nycomed Pharma AS Fast wet-massing method for the preparation of calcium-containing compositions
CA2601755C (en) 2005-02-03 2014-07-29 Nycomed Pharma As Melt granulation of a composition containing a calcium-containing compound
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CN105106233A (zh) * 2015-08-28 2015-12-02 江苏福邦药业有限公司 一种高溶出度小儿碳酸钙d3颗粒及其制备方法
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Also Published As

Publication number Publication date
AU6481999A (en) 2000-06-05
US20100119621A1 (en) 2010-05-13
WO2000028973A1 (en) 2000-05-25
PL348040A1 (en) 2002-05-06
SI1128815T1 (sl) 2007-04-30
US20050232989A1 (en) 2005-10-20
EA004951B1 (ru) 2004-10-28
CN1326338A (zh) 2001-12-12
TR200101347T2 (tr) 2001-08-21
GB9825033D0 (en) 1999-01-13
PT1128815E (pt) 2007-01-31
NO20012348D0 (no) 2001-05-11
EA200100415A1 (ru) 2001-12-24
CN1183902C (zh) 2005-01-12
CA2349565A1 (en) 2000-05-25
PL197146B1 (pl) 2008-03-31
JP2002529496A (ja) 2002-09-10
NO20012348L (no) 2001-07-03
EP1128815A1 (en) 2001-09-05
US8007752B2 (en) 2011-08-30
UA73727C2 (uk) 2005-09-15
EE04740B1 (et) 2006-12-15
US20070224268A1 (en) 2007-09-27
ES2273510T3 (es) 2007-05-01
DE69933689T2 (de) 2007-08-23
ATE342714T1 (de) 2006-11-15
DE69933689D1 (de) 2006-11-30
EP1743629A1 (en) 2007-01-17
US7638143B2 (en) 2009-12-29
CY1106299T1 (el) 2011-10-12
HK1040615B (zh) 2007-05-25
HK1040615A1 (en) 2002-06-21
JP4213867B2 (ja) 2009-01-21
NO331462B1 (no) 2012-01-09
EE200100260A (et) 2002-12-16
EP1128815B1 (en) 2006-10-18
CA2349565C (en) 2007-01-16

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