DK1054955T3 - Sammensætninger omfattende vira og fremgangsmåde til at opkoncentrere viruspræparater - Google Patents
Sammensætninger omfattende vira og fremgangsmåde til at opkoncentrere viruspræparaterInfo
- Publication number
- DK1054955T3 DK1054955T3 DK99906690T DK99906690T DK1054955T3 DK 1054955 T3 DK1054955 T3 DK 1054955T3 DK 99906690 T DK99906690 T DK 99906690T DK 99906690 T DK99906690 T DK 99906690T DK 1054955 T3 DK1054955 T3 DK 1054955T3
- Authority
- DK
- Denmark
- Prior art keywords
- viruses
- compositions
- methods
- virus preparations
- concentrating virus
- Prior art date
Links
- 241000700605 Viruses Species 0.000 title 2
- 238000000034 method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10351—Methods of production or purification of viral material
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2446298A | 1998-02-17 | 1998-02-17 | |
| US7964398A | 1998-05-15 | 1998-05-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1054955T3 true DK1054955T3 (da) | 2007-01-15 |
Family
ID=26698472
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99906690T DK1054955T3 (da) | 1998-02-17 | 1999-02-12 | Sammensætninger omfattende vira og fremgangsmåde til at opkoncentrere viruspræparater |
Country Status (25)
| Country | Link |
|---|---|
| EP (4) | EP1526174B1 (id) |
| JP (3) | JP4358434B2 (id) |
| KR (5) | KR100991683B1 (id) |
| CN (2) | CN101164623B (id) |
| AR (3) | AR020054A1 (id) |
| AT (3) | ATE478945T1 (id) |
| AU (1) | AU757976B2 (id) |
| BR (1) | BR9908015A (id) |
| CA (2) | CA2320419C (id) |
| CO (1) | CO4820440A1 (id) |
| DE (3) | DE69933433T2 (id) |
| DK (1) | DK1054955T3 (id) |
| ES (2) | ES2290613T3 (id) |
| HK (3) | HK1028416A1 (id) |
| HU (1) | HU226015B1 (id) |
| ID (1) | ID28298A (id) |
| IL (2) | IL137510A0 (id) |
| MY (1) | MY141641A (id) |
| NO (1) | NO20004104L (id) |
| PE (1) | PE20000265A1 (id) |
| PL (1) | PL197747B1 (id) |
| PT (1) | PT1054955E (id) |
| SK (1) | SK11842000A3 (id) |
| TW (1) | TWI232107B (id) |
| WO (1) | WO1999041416A2 (id) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7732129B1 (en) | 1998-12-01 | 2010-06-08 | Crucell Holland B.V. | Method for the production and purification of adenoviral vectors |
| KR100503701B1 (ko) | 1996-11-20 | 2005-07-26 | 인트로겐 테라페티스, 인코퍼레이티드 | 아데노바이러스 벡터를 생산하고 정제하는 개선된 방법 |
| AU1729600A (en) * | 1998-11-16 | 2000-06-05 | Introgen Therapeutics, Inc. | Formulation of adenovirus for gene therapy |
| US6689600B1 (en) | 1998-11-16 | 2004-02-10 | Introgen Therapeutics, Inc. | Formulation of adenovirus for gene therapy |
| AU4346101A (en) | 2000-03-07 | 2001-09-17 | Merck & Co., Inc. | Adenovirus formulations |
| US7456009B2 (en) | 2000-03-07 | 2008-11-25 | Merck & Co., Inc. | Adenovirus formulations |
| US20020064860A1 (en) | 2000-11-29 | 2002-05-30 | Schering Corporation | Method for purifying adenoviruses |
| AU2002218535A8 (en) * | 2000-12-12 | 2008-01-17 | Japan Tobacco Inc | Pharmaceutical composition containing an active with a hemolytic action and a surfactant |
| CA2469491A1 (en) | 2001-12-12 | 2003-06-19 | Kerrie Setiawan | Composition for viral preservation |
| US20030153065A1 (en) * | 2002-01-14 | 2003-08-14 | Genvec, Inc. | Composition and method for maintaining non-enveloped viral vectors |
| MXPA04006995A (es) * | 2002-01-18 | 2005-07-13 | Schering Ag | Formulaciones estabilizadas de adenovirus. |
| CN1922308A (zh) | 2004-02-23 | 2007-02-28 | 克鲁塞尔荷兰公司 | 病毒纯化方法 |
| KR20070104339A (ko) | 2004-11-03 | 2007-10-25 | 인트로겐 테라페티스, 인코퍼레이티드 | 아데노바이러스 벡터의 생산과 정제를 위한 신규한 방법 |
| CA2590943C (en) | 2004-12-13 | 2013-10-22 | Canji, Inc. | Cell lines for production of replication-defective adenovirus |
| ATE412737T1 (de) | 2005-04-11 | 2008-11-15 | Crucell Holland Bv | Virusreinigung mit ultrafiltration |
| CN1961961B (zh) * | 2005-11-11 | 2010-05-26 | 深圳市源兴生物医药科技有限公司 | 一种药物制剂及其制备方法 |
| WO2007070392A2 (en) | 2005-12-12 | 2007-06-21 | Canji, Inc. | Adenoviral expression vectors having an expression cassette in the e1 region and an inactivated e2b polymerase |
| DK2007883T3 (da) * | 2006-04-20 | 2012-02-06 | Wyeth Llc | Rensningsfremgangsmåder til isolering af renset vesikulær stomatitis-virus fra cellekultur |
| MX2011004292A (es) | 2008-11-03 | 2011-05-31 | Crucell Holland Bv | Metodo para la produccion de vectores adenovirales. |
| MX356669B (es) | 2009-05-02 | 2018-06-08 | Genzyme Corp | Terapia genica para trastornos neurodegenerativos. |
| EA023816B1 (ru) | 2010-02-15 | 2016-07-29 | Круселл Холланд Б.В. | СПОСОБ ПРОДУЦИРОВАНИЯ ВИРУСНЫХ ЧАСТИЦ Ad26 |
| AP3390A (en) | 2010-09-20 | 2015-08-31 | Crucell Holland Bv | Therapeutic vaccination against active tuberculosis |
| BR112013004582A2 (pt) | 2010-09-27 | 2016-09-06 | Crucell Holland Bv | método para induzir uma resposta imune em um sujeito contra um antígeno de um parasita que causa a malária |
| US9044498B2 (en) | 2010-12-02 | 2015-06-02 | Oncolytics Biotech Inc. | Lyophilized viral formulations |
| JP6034798B2 (ja) * | 2010-12-02 | 2016-11-30 | オンコリティクス バイオテク，インコーポレーテッド | 液体ウイルス製剤 |
| MX337348B (es) * | 2011-04-29 | 2016-02-29 | Oncolytics Biotech Inc | Metodos para purificar virus utilizando cromatografia de permeacion en gel. |
| US8932607B2 (en) | 2012-03-12 | 2015-01-13 | Crucell Holland B.V. | Batches of recombinant adenovirus with altered terminal ends |
| WO2013135615A1 (en) | 2012-03-12 | 2013-09-19 | Crucell Holland B.V. | Batches of recombinant adenovirus with altered terminal ends |
| AU2013237424B2 (en) | 2012-03-22 | 2017-07-06 | Janssen Vaccines & Prevention B.V. | Vaccine against RSV |
| US9125870B2 (en) | 2012-03-22 | 2015-09-08 | Crucell Holland B.V. | Vaccine against RSV |
| TR201902513T4 (tr) | 2013-04-25 | 2019-03-21 | Janssen Vaccines & Prevention Bv | Stabilize edilmiş çözünebilir prefüzyon RSV F polipeptitleri. |
| MY171210A (en) | 2013-06-17 | 2019-10-02 | Janssen Vaccines & Prevention Bv | Stabilized soluble pre-fusion rsv f polypeptides |
| US10280195B2 (en) * | 2014-05-28 | 2019-05-07 | Agency For Science, Technology And Research | Virus reduction method |
| PL3283634T3 (pl) | 2015-04-14 | 2019-10-31 | Janssen Vaccines & Prevention Bv | Rekombinowany adenowirus eksprymujący dwa transgeny z dwukierunkowym promotorem |
| BR112017028449A2 (pt) | 2015-07-07 | 2018-09-04 | Janssen Vaccines & Prevention Bv | polipeptídeos rsv f pré-fusão solúveis estabilizados |
| EP3319633B1 (en) | 2015-07-07 | 2020-11-11 | Janssen Vaccines & Prevention B.V. | Vaccine against rsv |
| KR102506895B1 (ko) | 2016-04-05 | 2023-03-08 | 얀센 백신스 앤드 프리벤션 비.브이. | 안정화된 용해성 융합-전 rsv f 단백질 |
| EA201892250A1 (ru) | 2016-04-05 | 2019-03-29 | Янссен Вэксинс Энд Превеншн Б.В. | Вакцина против rsv |
| AU2017272504A1 (en) | 2016-05-30 | 2018-11-29 | Janssen Vaccines & Prevention B.V. | Stabilized pre-fusion RSV F proteins |
| RU2745500C2 (ru) | 2016-06-20 | 2021-03-25 | Янссен Вэксинс Энд Превеншн Б.В. | Эффективный и сбалансированный двунаправленный промотор |
| EP3484506A1 (en) | 2016-07-14 | 2019-05-22 | Janssen Vaccines & Prevention B.V. | Hpv vaccines |
| JP2020519663A (ja) | 2017-05-17 | 2020-07-02 | ヤンセン ファッシンズ アンド プリベンション ベーフェーＪａｎｓｓｅｎ Ｖａｃｃｉｎｅｓ ＆ Ｐｒｅｖｅｎｔｉｏｎ Ｂ．Ｖ． | Ｒｓｖ感染に対する防御免疫を誘導するための方法及び組成物 |
| WO2018210871A1 (en) | 2017-05-17 | 2018-11-22 | Janssen Vaccines & Prevention B.V. | Methods and compositions for inducing protective immunity against rsv infection |
| WO2019021305A1 (en) * | 2017-07-24 | 2019-01-31 | Ella Foundation | VACCINE AGAINST FOOT AND MOUTH DISEASE |
| WO2019053109A1 (en) | 2017-09-15 | 2019-03-21 | Janssen Vaccines & Prevention B.V. | METHOD FOR SAFE INDUCTION OF IMMUNITY AGAINST RSV |
| JP2022539148A (ja) * | 2019-06-28 | 2022-09-07 | 武田薬品工業株式会社 | アデノ随伴ウイルスの精製方法 |
| US20230075527A1 (en) | 2020-01-31 | 2023-03-09 | Janssen Pharmaceuticals, Inc | Compositions and Methods for Preventing and Treating Coronavirus Infection - Sars-Cov-2 Vaccines |
| US20240228548A9 (en) | 2021-02-19 | 2024-07-11 | Janssen Vaccines & Prevention B.V. | Stabilized pre-fusion rsv fb antigens |
| WO2023020556A1 (zh) * | 2021-08-17 | 2023-02-23 | 上海行深生物科技有限公司 | 病毒制剂、用于配制病毒制剂的溶液及其用途 |
| WO2023020939A1 (en) | 2021-08-17 | 2023-02-23 | Janssen Pharmaceuticals, Inc. | Sars-cov-2 vaccines |
| WO2023111725A1 (en) | 2021-12-14 | 2023-06-22 | Janssen Pharmaceuticals, Inc. | Sars-cov-2 vaccines |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE299213C (id) * | ||||
| US4147772A (en) * | 1976-02-03 | 1979-04-03 | Merck & Co., Inc. | Vaccine stabilizer |
| GB1575155A (en) * | 1978-04-11 | 1980-09-17 | Merck & Co Inc | Vaccine stabilizer |
| BE866330A (fr) * | 1978-04-25 | 1978-10-25 | Merck & Co Inc | Procede de fabrication d'un agent de stabilisation de vaccin |
| US5532220A (en) | 1987-08-31 | 1996-07-02 | The Regents Of The University Of California | Genetic mechanisms of tumor suppression |
| DD299213A7 (de) * | 1988-05-04 | 1992-04-09 | Saechsische Landesgewerbefoerderungsgesellschaft M.B.H.,De | Verfahren zur stabilisierung eines lebendvirusimpfstoffes gegen temperatureinwirkung |
| DD295927A5 (de) * | 1988-05-06 | 1991-11-14 | Saechsisches Serumwerk Gmbh Dresden, | Immobilisiertes immunologisch aktives reagens |
| SK283703B6 (sk) | 1993-10-25 | 2003-12-02 | Canji, Inc. | Rekombinantný adenovírusový vektor a jeho použitie |
| KR100368686B1 (ko) * | 1994-12-29 | 2003-12-01 | 주식회사 엘지생명과학 | 수크로즈를이용한세포와바이러스의분리방법 |
| FR2742756B1 (fr) * | 1995-12-22 | 1998-04-03 | Pasteur Merieux Serums Vacc | Stabilisants pour vaccins vivants, vaccins les contenant et procedes pour leur preparation |
| US5789244A (en) * | 1996-01-08 | 1998-08-04 | Canji, Inc. | Compositions and methods for the treatment of cancer using recombinant viral vector delivery systems |
-
1999
- 1999-02-12 KR KR1020097004676A patent/KR100991683B1/ko not_active IP Right Cessation
- 1999-02-12 KR KR1020087008928A patent/KR100912362B1/ko not_active IP Right Cessation
- 1999-02-12 DE DE69933433T patent/DE69933433T2/de not_active Expired - Lifetime
- 1999-02-12 ES ES04030395T patent/ES2290613T3/es not_active Expired - Lifetime
- 1999-02-12 AT AT06019642T patent/ATE478945T1/de not_active IP Right Cessation
- 1999-02-12 DE DE69942708T patent/DE69942708D1/de not_active Expired - Lifetime
- 1999-02-12 CN CN2007101670867A patent/CN101164623B/zh not_active Expired - Fee Related
- 1999-02-12 EP EP04030395A patent/EP1526174B1/en not_active Expired - Lifetime
- 1999-02-12 CN CNB998050989A patent/CN100374551C/zh not_active Expired - Fee Related
- 1999-02-12 IL IL13751099A patent/IL137510A0/xx unknown
- 1999-02-12 AT AT04030395T patent/ATE371020T1/de not_active IP Right Cessation
- 1999-02-12 EP EP06019642A patent/EP1741777B1/en not_active Expired - Lifetime
- 1999-02-12 AU AU26538/99A patent/AU757976B2/en not_active Ceased
- 1999-02-12 KR KR1020097022935A patent/KR101018992B1/ko not_active IP Right Cessation
- 1999-02-12 EP EP04030394A patent/EP1526173B1/en not_active Expired - Lifetime
- 1999-02-12 KR KR1020087008929A patent/KR100918187B1/ko not_active IP Right Cessation
- 1999-02-12 CA CA2320419A patent/CA2320419C/en not_active Expired - Fee Related
- 1999-02-12 TW TW088102219A patent/TWI232107B/zh not_active IP Right Cessation
- 1999-02-12 HU HU0100670A patent/HU226015B1/hu not_active IP Right Cessation
- 1999-02-12 SK SK1184-2000A patent/SK11842000A3/sk unknown
- 1999-02-12 PL PL342847A patent/PL197747B1/pl not_active IP Right Cessation
- 1999-02-12 CA CA2723040A patent/CA2723040A1/en not_active Abandoned
- 1999-02-12 ES ES99906690T patent/ES2272053T3/es not_active Expired - Lifetime
- 1999-02-12 EP EP99906690A patent/EP1054955B1/en not_active Expired - Lifetime
- 1999-02-12 ID IDW20001574A patent/ID28298A/id unknown
- 1999-02-12 PT PT99906690T patent/PT1054955E/pt unknown
- 1999-02-12 DE DE69936948T patent/DE69936948T2/de not_active Expired - Lifetime
- 1999-02-12 WO PCT/US1999/001873 patent/WO1999041416A2/en active IP Right Grant
- 1999-02-12 JP JP2000531596A patent/JP4358434B2/ja not_active Expired - Fee Related
- 1999-02-12 KR KR1020007008878A patent/KR100862169B1/ko not_active IP Right Cessation
- 1999-02-12 BR BR9908015-0A patent/BR9908015A/pt not_active Application Discontinuation
- 1999-02-12 AT AT99906690T patent/ATE341614T1/de not_active IP Right Cessation
- 1999-02-12 DK DK99906690T patent/DK1054955T3/da active
- 1999-02-15 MY MYPI99000542A patent/MY141641A/en unknown
- 1999-02-16 PE PE1999000137A patent/PE20000265A1/es not_active Application Discontinuation
- 1999-02-16 CO CO99009282A patent/CO4820440A1/es unknown
- 1999-02-23 AR ARP990100656A patent/AR020054A1/es active IP Right Grant
-
2000
- 2000-07-25 IL IL137510A patent/IL137510A/en not_active IP Right Cessation
- 2000-08-16 NO NO20004104A patent/NO20004104L/no not_active Application Discontinuation
- 2000-12-01 HK HK00107727A patent/HK1028416A1/xx not_active IP Right Cessation
- 2000-12-01 HK HK05106734A patent/HK1073481A1/xx not_active IP Right Cessation
-
2006
- 2006-02-07 JP JP2006030336A patent/JP2006166925A/ja not_active Withdrawn
-
2007
- 2007-05-10 HK HK07104995.0A patent/HK1097413A1/xx not_active IP Right Cessation
- 2007-10-16 AR ARP070104577A patent/AR063315A2/es unknown
- 2007-10-16 AR ARP070104576A patent/AR063314A2/es unknown
-
2010
- 2010-07-08 JP JP2010156257A patent/JP2010213727A/ja not_active Withdrawn
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