DK1054955T3 - Sammensætninger omfattende vira og fremgangsmåde til at opkoncentrere viruspræparater - Google Patents

Sammensætninger omfattende vira og fremgangsmåde til at opkoncentrere viruspræparater

Info

Publication number
DK1054955T3
DK1054955T3 DK99906690T DK99906690T DK1054955T3 DK 1054955 T3 DK1054955 T3 DK 1054955T3 DK 99906690 T DK99906690 T DK 99906690T DK 99906690 T DK99906690 T DK 99906690T DK 1054955 T3 DK1054955 T3 DK 1054955T3
Authority
DK
Denmark
Prior art keywords
viruses
compositions
methods
virus preparations
concentrating virus
Prior art date
Application number
DK99906690T
Other languages
English (en)
Inventor
Andreas Frei
Henry K H Kwan
Varda E Sandweiss
Gary J Vellekamp
Pui-Ho Yuen
Laureano L Bondoc Jr
John Chu-Tay Tang
Peter Ihnat
Frederick William Porter Iv
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of DK1054955T3 publication Critical patent/DK1054955T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10351Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK99906690T 1998-02-17 1999-02-12 Sammensætninger omfattende vira og fremgangsmåde til at opkoncentrere viruspræparater DK1054955T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2446298A 1998-02-17 1998-02-17
US7964398A 1998-05-15 1998-05-15

Publications (1)

Publication Number Publication Date
DK1054955T3 true DK1054955T3 (da) 2007-01-15

Family

ID=26698472

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99906690T DK1054955T3 (da) 1998-02-17 1999-02-12 Sammensætninger omfattende vira og fremgangsmåde til at opkoncentrere viruspræparater

Country Status (25)

Country Link
EP (4) EP1526173B1 (da)
JP (3) JP4358434B2 (da)
KR (5) KR101018992B1 (da)
CN (2) CN100374551C (da)
AR (3) AR020054A1 (da)
AT (3) ATE371020T1 (da)
AU (1) AU757976B2 (da)
BR (1) BR9908015A (da)
CA (2) CA2320419C (da)
CO (1) CO4820440A1 (da)
DE (3) DE69936948T2 (da)
DK (1) DK1054955T3 (da)
ES (2) ES2290613T3 (da)
HK (3) HK1028416A1 (da)
HU (1) HU226015B1 (da)
ID (1) ID28298A (da)
IL (2) IL137510A0 (da)
MY (1) MY141641A (da)
NO (1) NO20004104L (da)
PE (1) PE20000265A1 (da)
PL (1) PL197747B1 (da)
PT (1) PT1054955E (da)
SK (1) SK11842000A3 (da)
TW (1) TWI232107B (da)
WO (1) WO1999041416A2 (da)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE550429T1 (de) 1996-11-20 2012-04-15 Crucell Holland Bv Adenovirus-zusammensetzungen erhältlich durch ein verbessertes produktions- und reinigungsverfahren
US7732129B1 (en) 1998-12-01 2010-06-08 Crucell Holland B.V. Method for the production and purification of adenoviral vectors
US6689600B1 (en) 1998-11-16 2004-02-10 Introgen Therapeutics, Inc. Formulation of adenovirus for gene therapy
EP1977764A1 (en) * 1998-11-16 2008-10-08 Introgen Therapeutics, Inc. Formulation of adenovirus for gene therapy
CA2399321C (en) 2000-03-07 2013-04-30 Robert K. Evans Adenovirus formulations
US7456009B2 (en) 2000-03-07 2008-11-25 Merck & Co., Inc. Adenovirus formulations
US20020064860A1 (en) 2000-11-29 2002-05-30 Schering Corporation Method for purifying adenoviruses
AU2002218535A1 (en) * 2000-12-12 2002-06-24 Japan Tobacco Inc. Pharmaceutical composition containing an active with a hemolytic action and a surfactant
EP1453536A4 (en) 2001-12-12 2009-08-26 Mayne Pharma Int Pty Ltd COMPOSITION FOR PRESERVING VIRUSES
US20030153065A1 (en) * 2002-01-14 2003-08-14 Genvec, Inc. Composition and method for maintaining non-enveloped viral vectors
IL162404A0 (en) * 2002-01-18 2005-11-20 Schering Ag Stabilized formulations of adenovirus
EP1718738A2 (en) 2004-02-23 2006-11-08 Crucell Holland B.V. Virus purification methods
AU2005305347A1 (en) 2004-11-03 2006-05-18 Introgen Therapeutics Inc. Method of producing and purifying of adenoviral vectors
CN101208425B (zh) 2004-12-13 2011-01-26 坎吉有限公司 产生复制缺陷型腺病毒的细胞系
ATE412737T1 (de) 2005-04-11 2008-11-15 Crucell Holland Bv Virusreinigung mit ultrafiltration
CN1961961B (zh) * 2005-11-11 2010-05-26 深圳市源兴生物医药科技有限公司 一种药物制剂及其制备方法
WO2007070392A2 (en) 2005-12-12 2007-06-21 Canji, Inc. Adenoviral expression vectors having an expression cassette in the e1 region and an inactivated e2b polymerase
EP2007883B1 (en) * 2006-04-20 2011-12-28 Wyeth LLC Purification processes for isolating purified vesicular stomatitis virus from cell culture
CA2742474C (en) 2008-11-03 2016-05-31 Crucell Holland B.V. Method for the production of adenoviral vectors
CA2759801C (en) 2009-05-02 2019-04-02 Marco A. Passini Gene therapy for neurodegenerative disorders
AU2011214262B2 (en) 2010-02-15 2015-05-21 Crucell Holland B.V. Method for the production of Ad26 adenoviral vectors
AP3390A (en) 2010-09-20 2015-08-31 Crucell Holland Bv Therapeutic vaccination against active tuberculosis
BR112013004582A2 (pt) 2010-09-27 2016-09-06 Crucell Holland Bv método para induzir uma resposta imune em um sujeito contra um antígeno de um parasita que causa a malária
TW201233802A (en) 2010-12-02 2012-08-16 Oncolytics Biotech Inc Liquid viral formulations
DK2646052T3 (da) 2010-12-02 2017-07-17 Oncolytics Biotech Inc Lyofiliserede virale formuleringer
DK2702147T3 (da) * 2011-04-29 2020-09-28 Oncolytics Biotech Inc Fremgangsmåder til oprensning af vira ved hjælp af gelpermeationskromatografi
AU2013231423B2 (en) 2012-03-12 2018-10-04 Janssen Vaccines & Prevention B.V. Batches of recombinant adenovirus with altered terminal ends
US8932607B2 (en) 2012-03-12 2015-01-13 Crucell Holland B.V. Batches of recombinant adenovirus with altered terminal ends
AP2014007993A0 (en) 2012-03-22 2014-10-31 Crucell Holland Bv Vaccine against RSV
US9119813B2 (en) 2012-03-22 2015-09-01 Crucell Holland B.V. Vaccine against RSV
PL2988780T3 (pl) 2013-04-25 2019-06-28 Janssen Vaccines & Prevention B.V. Stabilizowane rozpuszczalne prefuzyjne polipeptydy F RSV
WO2014202570A1 (en) 2013-06-17 2014-12-24 Crucell Holland B.V. Stabilized soluble pre-fusion rsv f polypeptides
SG11201609908VA (en) * 2014-05-28 2016-12-29 Agency Science Tech & Res Virus reduction method
CN107466324B (zh) 2015-04-14 2022-01-14 扬森疫苗与预防公司 具有双向启动子的表达两种转基因的重组腺病毒
US10457708B2 (en) 2015-07-07 2019-10-29 Janssen Vaccines & Prevention B.V. Stabilized soluble pre-fusion RSV F polypeptides
KR102638978B1 (ko) 2015-07-07 2024-02-22 얀센 백신스 앤드 프리벤션 비.브이. Rsv에 대한 백신
KR102506895B1 (ko) 2016-04-05 2023-03-08 얀센 백신스 앤드 프리벤션 비.브이. 안정화된 용해성 융합-전 rsv f 단백질
CA3018139A1 (en) 2016-04-05 2017-10-12 Janssen Vaccines & Prevention B.V. Vaccine against rsv
KR102421049B1 (ko) 2016-05-30 2022-07-15 얀센 백신스 앤드 프리벤션 비.브이. 안정화된 융합-전 rsv f 단백질
CN109312362B (zh) 2016-06-20 2022-06-28 扬森疫苗与预防公司 有效和平衡的双向启动子
US10744196B2 (en) 2016-07-14 2020-08-18 Janssen Vaccines & Prevention B.V. HPV vaccines
CA3061278A1 (en) 2017-05-17 2018-11-22 Janssen Vaccines & Prevention B.V. Methods and compositions for inducing protective immunity against rsv infection
WO2018210871A1 (en) 2017-05-17 2018-11-22 Janssen Vaccines & Prevention B.V. Methods and compositions for inducing protective immunity against rsv infection
WO2019021305A1 (en) * 2017-07-24 2019-01-31 Ella Foundation VACCINE AGAINST FOOT AND MOUTH DISEASE
KR20200053518A (ko) 2017-09-15 2020-05-18 얀센 백신스 앤드 프리벤션 비.브이. Rsv에 대한 면역의 안전한 유도를 위한 방법
CN114173827A (zh) * 2019-06-28 2022-03-11 武田药品工业株式会社 腺相关病毒纯化方法
CN116096732A (zh) 2020-01-31 2023-05-09 贝斯以色列护理医疗中心有限公司 用于预防和治疗冠状病毒感染的组合物和方法-sars-cov-2疫苗
CA3211034A1 (en) 2021-02-19 2022-08-25 Janssen Vaccines & Prevention B.V. Stabilized pre-fusion rsv fb antigens
WO2023020556A1 (zh) * 2021-08-17 2023-02-23 上海行深生物科技有限公司 病毒制剂、用于配制病毒制剂的溶液及其用途
WO2023020939A1 (en) 2021-08-17 2023-02-23 Janssen Pharmaceuticals, Inc. Sars-cov-2 vaccines
WO2023111725A1 (en) 2021-12-14 2023-06-22 Janssen Pharmaceuticals, Inc. Sars-cov-2 vaccines

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE299213C (da) *
US4147772A (en) * 1976-02-03 1979-04-03 Merck & Co., Inc. Vaccine stabilizer
GB1575155A (en) * 1978-04-11 1980-09-17 Merck & Co Inc Vaccine stabilizer
BE866330A (fr) * 1978-04-25 1978-10-25 Merck & Co Inc Procede de fabrication d'un agent de stabilisation de vaccin
US5532220A (en) 1987-08-31 1996-07-02 The Regents Of The University Of California Genetic mechanisms of tumor suppression
DD299213A7 (de) * 1988-05-04 1992-04-09 Saechsische Landesgewerbefoerderungsgesellschaft M.B.H.,De Verfahren zur stabilisierung eines lebendvirusimpfstoffes gegen temperatureinwirkung
DD295927A5 (de) * 1988-05-06 1991-11-14 Saechsisches Serumwerk Gmbh Dresden, Immobilisiertes immunologisch aktives reagens
PT797676E (pt) 1993-10-25 2006-05-31 Canji Inc Vector adenoviral recombinante e metodos de utilizacao
KR100368686B1 (ko) * 1994-12-29 2003-12-01 주식회사 엘지생명과학 수크로즈를이용한세포와바이러스의분리방법
FR2742756B1 (fr) * 1995-12-22 1998-04-03 Pasteur Merieux Serums Vacc Stabilisants pour vaccins vivants, vaccins les contenant et procedes pour leur preparation
US5789244A (en) 1996-01-08 1998-08-04 Canji, Inc. Compositions and methods for the treatment of cancer using recombinant viral vector delivery systems

Also Published As

Publication number Publication date
KR100918187B1 (ko) 2009-09-22
HK1073481A1 (en) 2005-10-07
IL137510A0 (en) 2001-07-24
EP1526173A3 (en) 2005-08-10
KR20090038927A (ko) 2009-04-21
ATE478945T1 (de) 2010-09-15
SK11842000A3 (sk) 2001-05-10
EP1526174B1 (en) 2007-08-22
CN1297478A (zh) 2001-05-30
ES2290613T3 (es) 2008-02-16
BR9908015A (pt) 2001-04-24
IL137510A (en) 2012-10-31
HUP0100670A2 (hu) 2001-06-28
EP1526173A2 (en) 2005-04-27
EP1741777B1 (en) 2010-08-25
KR101018992B1 (ko) 2011-03-07
DE69942708D1 (de) 2010-10-07
TWI232107B (en) 2005-05-11
NO20004104L (no) 2000-10-17
KR100912362B1 (ko) 2009-08-19
KR20080065614A (ko) 2008-07-14
MY141641A (en) 2010-05-31
HK1097413A1 (en) 2007-06-22
NO20004104D0 (no) 2000-08-16
HK1028416A1 (en) 2001-02-16
ID28298A (id) 2001-05-10
CA2320419C (en) 2011-02-08
EP1526174A2 (en) 2005-04-27
PT1054955E (pt) 2007-01-31
AR020054A1 (es) 2002-04-10
EP1526174A3 (en) 2005-08-31
DE69933433D1 (de) 2006-11-16
WO1999041416A3 (en) 1999-11-18
CN100374551C (zh) 2008-03-12
EP1526173B1 (en) 2012-11-21
DE69936948D1 (de) 2007-10-04
PE20000265A1 (es) 2000-04-25
CA2723040A1 (en) 1999-08-19
JP2006166925A (ja) 2006-06-29
ATE341614T1 (de) 2006-10-15
JP2010213727A (ja) 2010-09-30
KR20090127947A (ko) 2009-12-14
JP2002503484A (ja) 2002-02-05
PL197747B1 (pl) 2008-04-30
KR20080065615A (ko) 2008-07-14
CN101164623B (zh) 2012-11-14
JP4358434B2 (ja) 2009-11-04
KR100991683B1 (ko) 2010-11-04
CN101164623A (zh) 2008-04-23
DE69936948T2 (de) 2008-05-15
KR20010072547A (ko) 2001-07-31
AR063315A2 (es) 2009-01-21
DE69933433T2 (de) 2007-08-23
ES2272053T3 (es) 2007-04-16
EP1054955B1 (en) 2006-10-04
HU226015B1 (en) 2008-02-28
CA2320419A1 (en) 1999-08-19
EP1054955A2 (en) 2000-11-29
EP1741777A1 (en) 2007-01-10
WO1999041416A2 (en) 1999-08-19
PL342847A1 (en) 2001-07-16
CO4820440A1 (es) 1999-07-28
AU2653899A (en) 1999-08-30
AR063314A2 (es) 2009-01-21
AU757976B2 (en) 2003-03-13
HUP0100670A3 (en) 2003-10-28
KR100862169B1 (ko) 2008-10-09
ATE371020T1 (de) 2007-09-15

Similar Documents

Publication Publication Date Title
DK1054955T3 (da) Sammensætninger omfattende vira og fremgangsmåde til at opkoncentrere viruspræparater
NO20025627L (no) Fremgangsmåter og sammensetninger for å behandle hepatitt C virus
IS5953A (is) Lyfjablöndur úr örgerðum eplerenonum
ID21649A (id) Inhibitor serum protease, terutama virus hepatitis c ns3 protease
DK1109453T3 (da) Sammensætninger og fremgangsmåder til behandling af mitokondrielle sygdomme
GB2337755B (en) Virus vaccine
ID27457A (id) Komposisi untuk pengobatan hiv dan infeksi virus lainnya
DK1152765T3 (da) Ethanolat af azithromycin, fremgangsmåde til fremstilling og farmaceutiske sammensætninger deraf
EP1305438A4 (en) IMPROVED VIRUS-SIMILAR PARTICLES BUILDING ON THE HEPATITIS B SMALL SLEEP PROTEIN
NO20011162L (no) Fremgangsmåter og preparater for modulering av interaksjonen mellom APJ-reseptoren og HIV-viruset
NO971495D0 (no) Svekkede virus og fremgangsmåte til deres fremstilling
ATE297761T1 (de) Zubereitungen zur stabilisierung von peg- interferon alpha konjugaten
IS5777A (is) Bóluefnisvakið lifrarbólgu B veiruafbrigði og notkun þess
NO983472D0 (no) Taxoider, deres fremstilling og farmas°ytiske preparater inneholdende taxoidene
NO20010464L (no) FremgangsmÕter og preparater for behandling av gastro- øsofagealt-reflukssyndrom
NO20022969L (no) Sammensetninger og metoder for L-nukleosider, L-nukleotider og analoger derav
DK0672352T3 (da) Fremgangsmåder til fremstilling af glutaminrige peptider og næringsmiddelsammensætninger fremstillet dermed
NO20024325D0 (no) Rensede hepatitt C-viruskappeproteiner for diagnostisk og terapeutisk anvendelse
ZA991235B (en) Compositions comprising viruses and methods for concentrating virus preparations.
NO991227D0 (no) PTX-sensitive G-proteiner, deres fremstilling og bruk
NO20041815L (no) Fremgangsmater for a behandle leverfibrose og hepatitt C-virusinfeksjon
DE69824881D1 (de) Kompakte replikons des epstein-barr-virus.
JP2002519670A5 (ja) C型レトロウイルス感染の検出のための方法および組成物
DK1064393T3 (da) Sammensætninger og fremgangsmåder til hjælper-fri produktion af rekombinante adenoassocierede virusser
HU0800022D0 (en) Method for concentrating virus preparations